PL431139A1 - Kompozycja farmaceutyczna bimatoprostu i tymololu - Google Patents
Kompozycja farmaceutyczna bimatoprostu i tymololuInfo
- Publication number
- PL431139A1 PL431139A1 PL431139A PL43113919A PL431139A1 PL 431139 A1 PL431139 A1 PL 431139A1 PL 431139 A PL431139 A PL 431139A PL 43113919 A PL43113919 A PL 43113919A PL 431139 A1 PL431139 A1 PL 431139A1
- Authority
- PL
- Poland
- Prior art keywords
- bimatoprost
- timolol
- pharmaceutical composition
- application
- preservative
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
Abstract
Przedmiotem zgłoszenia jest kompozycja farmaceutyczna bimatoprostu i tymololu, do stosowania w celu obniżenia ciśnienia wewnątrzgałkowego u pacjenta, która stanowi niezawierający konserwantów sterylny roztwór wodny o następującej recepturze: 0,03% wag. bimatoprostu, 0,5% wag. tymololu, 0,358% wag. dodekahydratu dwuzasadowego fosforanu sodu, 0,014% wag. monohydratu kwasu cytrynowego, 0,72% wag. chlorku sodu, woda z pH na poziomie 7,3. Zgłoszenie obejmuje także sposób otrzymywania powyższej kompozycji.
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL431139A PL431139A1 (pl) | 2019-09-13 | 2019-09-13 | Kompozycja farmaceutyczna bimatoprostu i tymololu |
PCT/PL2020/050066 WO2021049963A1 (en) | 2019-09-13 | 2020-09-13 | Pharmaceutical composition of bimatoprost and timolol |
EP20797887.5A EP4027977A1 (en) | 2019-09-13 | 2020-09-13 | Pharmaceutical composition of bimatoprost and timolol |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL431139A PL431139A1 (pl) | 2019-09-13 | 2019-09-13 | Kompozycja farmaceutyczna bimatoprostu i tymololu |
Publications (1)
Publication Number | Publication Date |
---|---|
PL431139A1 true PL431139A1 (pl) | 2021-03-22 |
Family
ID=73030187
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL431139A PL431139A1 (pl) | 2019-09-13 | 2019-09-13 | Kompozycja farmaceutyczna bimatoprostu i tymololu |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP4027977A1 (pl) |
PL (1) | PL431139A1 (pl) |
WO (1) | WO2021049963A1 (pl) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2024003078A1 (en) * | 2022-06-27 | 2024-01-04 | Warszawskie Zaklady Farmaceutyczne Polfa Sa | Preservative-free ophthalmic composition comprising a prostaglandin analogue |
CN115998888A (zh) * | 2023-01-16 | 2023-04-25 | 广州楷石医药有限公司 | 用于治疗青光眼或高眼压症的药物组合物及其用途 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2807081C (en) * | 2010-07-29 | 2018-09-18 | Allergan, Inc. | Preservative free bimatoprost and timolol solutions |
GR1009006B (el) * | 2016-04-01 | 2017-04-04 | Φαρματεν Ανωνυμος Βιομηχανικη Και Εμπορικη Εταιρεια Φαρμακευτικων Ιατρικων Και Καλλυντικων Προϊοντων | Φαρμακευτικο σκευασμα ελευθερο συντηρητικου για οφθαλμικη χρηση περιεχον βιματοπροστη και τιμολολη |
CN108236721A (zh) * | 2016-12-26 | 2018-07-03 | 上海创诺医药集团有限公司 | 一种稳定的贝伐单抗制剂 |
-
2019
- 2019-09-13 PL PL431139A patent/PL431139A1/pl unknown
-
2020
- 2020-09-13 WO PCT/PL2020/050066 patent/WO2021049963A1/en unknown
- 2020-09-13 EP EP20797887.5A patent/EP4027977A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
EP4027977A1 (en) | 2022-07-20 |
WO2021049963A1 (en) | 2021-03-18 |
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