MY185134A - 6-substituted phenoxychroman carboxylic acis derivatives - Google Patents

6-substituted phenoxychroman carboxylic acis derivatives

Info

Publication number
MY185134A
MY185134A MYPI2014001094A MYPI2014001094A MY185134A MY 185134 A MY185134 A MY 185134A MY PI2014001094 A MYPI2014001094 A MY PI2014001094A MY PI2014001094 A MYPI2014001094 A MY PI2014001094A MY 185134 A MY185134 A MY 185134A
Authority
MY
Malaysia
Prior art keywords
derivatives
substituted
acis
phenoxychroman carboxylic
carboxylic acis
Prior art date
Application number
MYPI2014001094A
Other languages
English (en)
Inventor
Laurence E Burgess
Christopher T Clark
Adam Cook
Christopher P Corrette
Kirk Delisle Robert
George A Doherty
Kevin W Hunt
Todd Romoff
Ganghyeok Kim
Original Assignee
Array Biopharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Array Biopharma Inc filed Critical Array Biopharma Inc
Publication of MY185134A publication Critical patent/MY185134A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/20Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 hydrogenated in the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Otolaryngology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
MYPI2014001094A 2008-06-25 2009-06-24 6-substituted phenoxychroman carboxylic acis derivatives MY185134A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7561508P 2008-06-25 2008-06-25

Publications (1)

Publication Number Publication Date
MY185134A true MY185134A (en) 2021-04-30

Family

ID=40996727

Family Applications (2)

Application Number Title Priority Date Filing Date
MYPI2010006174A MY161425A (en) 2008-06-25 2009-06-24 6-substituted phenoxychroman carboxylic acid derivatives
MYPI2014001094A MY185134A (en) 2008-06-25 2009-06-24 6-substituted phenoxychroman carboxylic acis derivatives

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MYPI2010006174A MY161425A (en) 2008-06-25 2009-06-24 6-substituted phenoxychroman carboxylic acid derivatives

Country Status (33)

Country Link
US (4) US8569522B2 (ru)
EP (3) EP2826774B1 (ru)
JP (2) JP5753780B2 (ru)
KR (1) KR101728175B1 (ru)
CN (2) CN103450138B (ru)
AR (1) AR072301A1 (ru)
AU (1) AU2009262274B2 (ru)
BR (1) BRPI0915513B8 (ru)
CA (1) CA2729217C (ru)
CL (1) CL2010001528A1 (ru)
CO (1) CO6362002A2 (ru)
CR (1) CR20110037A (ru)
CY (1) CY1115650T1 (ru)
DK (1) DK2307397T3 (ru)
ES (2) ES2582161T3 (ru)
HK (1) HK1155735A1 (ru)
HR (1) HRP20140988T1 (ru)
IL (2) IL210198A (ru)
MX (1) MX2011000173A (ru)
MY (2) MY161425A (ru)
NZ (1) NZ590437A (ru)
PH (1) PH12014500079A1 (ru)
PL (1) PL2307397T3 (ru)
PT (1) PT2307397E (ru)
RS (1) RS53665B1 (ru)
RU (1) RU2507200C2 (ru)
SG (2) SG2014013528A (ru)
SI (1) SI2307397T1 (ru)
TW (2) TWI436990B (ru)
UA (1) UA104867C2 (ru)
UY (1) UY31938A (ru)
WO (1) WO2009158426A1 (ru)
ZA (1) ZA201100604B (ru)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2507200C2 (ru) 2008-06-25 2014-02-20 Эррэй Биофарма Инк. Производные феноксихроманкарбоновой кислоты, замещенные в 6-ом положении
WO2010075200A1 (en) * 2008-12-22 2010-07-01 Array Biopharma Inc. 7-phenoxychroman carboxylic acid derivatives
EP2457900A1 (en) 2010-11-25 2012-05-30 Almirall, S.A. New pyrazole derivatives having CRTh2 antagonistic behaviour
TWI654180B (zh) 2012-06-29 2019-03-21 美商艾佛艾姆希公司 殺真菌之雜環羧醯胺
TW201507722A (zh) * 2013-04-30 2015-03-01 Bayer Cropscience Ag 做為殺線蟲劑及殺體內寄生蟲劑的n-(2-鹵素-2-苯乙基)-羧醯胺類
WO2015126750A1 (en) 2014-02-19 2015-08-27 Array Biopharma Inc. BIOMARKERS PREDICTIVE OF RESPONSIVENESS TO TREATMENT WITH A CRTh2 INHIBITOR
CN111057003A (zh) * 2019-12-06 2020-04-24 广安凯特制药有限公司 一种立他司特中间体5,7-二氯-1,2,3,4-四氢异喹啉的合成方法
SE2151519A1 (en) * 2021-12-10 2023-06-11 Amidea Sweden Ab 2-(2,5-dimethoxyphenyl)ethanamine and uses thereof
CN114181039A (zh) * 2021-12-23 2022-03-15 凯美克(上海)医药科技有限公司 一种4,4-二苯基-3-丁烯-1-醇的合成方法

Family Cites Families (16)

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US5059609A (en) 1987-10-19 1991-10-22 Pfizer Inc. Substituted tetralins, chromans and related compounds in the treatment of asthma, arthritis and related diseases
US5006550A (en) * 1989-12-29 1991-04-09 Allergan, Inc. Chroman esters of phenols and benzoic acids having retinoid-like activity
US5952326A (en) 1997-12-10 1999-09-14 Pfizer Inc. Tetralin and chroman derivatives useful in the treatment of asthma, arthritis and related diseases
DE19850131A1 (de) * 1998-10-30 2000-05-04 Merck Patent Gmbh Chromenon- und Chromanonderivate
DK1178984T3 (da) 1999-05-21 2003-06-10 Pfizer Prod Inc 1-trifluormethyl-4-hydroxy-7-piperidinylaminomethylchroman-derivater
KR100884709B1 (ko) * 2000-09-14 2009-02-19 미쓰비시 타나베 파마 코퍼레이션 신규한 아미드 유도체의 광학 활성체 및 그의 의약적 용도
WO2003029239A1 (en) * 2001-10-04 2003-04-10 Wyeth Chroman and benzofuran derivatives as 5-hydroxytryptamine-6 ligands
BR0317591A (pt) 2002-12-20 2005-11-22 Amgen Inc Composto, sal ou pró-medicamento farmaceuticamente aceitáveis, composição farmacêutica, e, métodos para tratar uma doença ou condição, para modular a função de crth2 e/ou um ou mais outros receptores de pgd2 em uma célula e para modular crth2 e/ou um ou mais outros receptores de pgd2
CA2599352A1 (en) * 2005-02-25 2006-09-08 Eli Lilly And Company Novel lipoxygenase inhibitors
GB0611781D0 (en) * 2006-06-14 2006-07-26 Argenta Discovery Ltd 2-Oxo-2H-Chromene Compounds
AU2007286829B2 (en) 2006-08-21 2013-05-02 Array Biopharma, Inc. 4-substituted phenoxyphenylacetic acid derivatives
CA2667249A1 (en) * 2006-10-31 2008-05-08 Merck & Co., Inc. Antidiabetic bicyclic compounds
US7960567B2 (en) * 2007-05-02 2011-06-14 Amgen Inc. Compounds and methods useful for treating asthma and allergic inflammation
US8362056B2 (en) 2007-11-05 2013-01-29 Array Biopharma Inc. 4-heteroaryl-substituted phenoxyphenylacetic acid derivatives
RU2507200C2 (ru) 2008-06-25 2014-02-20 Эррэй Биофарма Инк. Производные феноксихроманкарбоновой кислоты, замещенные в 6-ом положении
WO2010075200A1 (en) * 2008-12-22 2010-07-01 Array Biopharma Inc. 7-phenoxychroman carboxylic acid derivatives

Also Published As

Publication number Publication date
EP3144303A1 (en) 2017-03-22
IL241754A0 (en) 2015-11-30
CA2729217C (en) 2016-09-06
PL2307397T3 (pl) 2015-02-27
HK1155735A1 (en) 2012-05-25
UY31938A (es) 2011-01-31
HRP20140988T1 (hr) 2014-12-05
KR101728175B1 (ko) 2017-04-18
CN103450138A (zh) 2013-12-18
CL2010001528A1 (es) 2011-07-01
US20140221342A1 (en) 2014-08-07
SG2014013544A (en) 2014-07-30
US9556139B2 (en) 2017-01-31
MX2011000173A (es) 2011-06-20
EP2307397A1 (en) 2011-04-13
PH12014500079B1 (en) 2015-02-09
US9096567B2 (en) 2015-08-04
AU2009262274B2 (en) 2013-08-01
CA2729217A1 (en) 2009-12-30
CY1115650T1 (el) 2017-01-04
KR20110027798A (ko) 2011-03-16
US8716498B2 (en) 2014-05-06
RS53665B1 (en) 2015-04-30
BRPI0915513A2 (pt) 2016-01-26
IL241754A (en) 2017-02-28
US20140005418A1 (en) 2014-01-02
ES2582161T3 (es) 2016-09-09
WO2009158426A1 (en) 2009-12-30
MY161425A (en) 2017-04-14
UA104867C2 (ru) 2014-03-25
SG2014013528A (en) 2014-07-30
CO6362002A2 (es) 2012-01-20
US8569522B2 (en) 2013-10-29
TW201022222A (en) 2010-06-16
EP2307397B1 (en) 2014-08-20
AU2009262274A1 (en) 2009-12-30
IL210198A0 (en) 2011-03-31
DK2307397T3 (da) 2014-11-03
US20150232442A1 (en) 2015-08-20
EP3144303B1 (en) 2018-09-26
BRPI0915513B8 (pt) 2021-05-25
IL210198A (en) 2015-10-29
SI2307397T1 (sl) 2014-11-28
JP5753780B2 (ja) 2015-07-22
TW201427965A (zh) 2014-07-16
JP2011526290A (ja) 2011-10-06
US20110105463A1 (en) 2011-05-05
EP2826774B1 (en) 2016-05-25
JP2014122241A (ja) 2014-07-03
ZA201100604B (en) 2015-08-26
BRPI0915513B1 (pt) 2019-11-19
CN102131794B (zh) 2013-09-25
CN102131794A (zh) 2011-07-20
RU2011102595A (ru) 2012-07-27
NZ590437A (en) 2012-07-27
PH12014500079A1 (en) 2015-02-09
PT2307397E (pt) 2014-10-29
CN103450138B (zh) 2015-04-08
TWI476186B (zh) 2015-03-11
ES2524314T3 (es) 2014-12-05
EP2826774A1 (en) 2015-01-21
TWI436990B (zh) 2014-05-11
CR20110037A (es) 2011-03-14
RU2507200C2 (ru) 2014-02-20
AR072301A1 (es) 2010-08-18

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