MY181404A - Antisense-oligonucleotides as inhibitors of tgf-r signaling - Google Patents

Antisense-oligonucleotides as inhibitors of tgf-r signaling

Info

Publication number
MY181404A
MY181404A MYPI2017701692A MYPI2017701692A MY181404A MY 181404 A MY181404 A MY 181404A MY PI2017701692 A MYPI2017701692 A MY PI2017701692A MY PI2017701692 A MYPI2017701692 A MY PI2017701692A MY 181404 A MY181404 A MY 181404A
Authority
MY
Malaysia
Prior art keywords
antisense
oligonucleotides
tgf
inhibitors
signaling
Prior art date
Application number
MYPI2017701692A
Other languages
English (en)
Inventor
Markus Hossbach
Monika Krampert
Hans-Lothar Arth
Original Assignee
Neurovision Pharma GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurovision Pharma GmbH filed Critical Neurovision Pharma GmbH
Publication of MY181404A publication Critical patent/MY181404A/en

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    • A61K31/7125—Nucleic acids or oligonucleotides having modified internucleoside linkage, i.e. other than 3'-5' phosphodiesters
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    • C12N2310/341—Gapmers, i.e. of the type ===---===
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    • C12Y207/11—Protein-serine/threonine kinases (2.7.11)
    • C12Y207/1103—Receptor protein serine/threonine kinase (2.7.11.30)

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MYPI2017701692A 2014-11-16 2015-11-16 Antisense-oligonucleotides as inhibitors of tgf-r signaling MY181404A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP14193368.9A EP3020813A1 (en) 2014-11-16 2014-11-16 Antisense-oligonucleotides as inhibitors of TGF-R signaling

Publications (1)

Publication Number Publication Date
MY181404A true MY181404A (en) 2020-12-21

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MYPI2017701692A MY181404A (en) 2014-11-16 2015-11-16 Antisense-oligonucleotides as inhibitors of tgf-r signaling

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US (4) US10363266B2 (enExample)
EP (3) EP3020813A1 (enExample)
JP (2) JP6832285B2 (enExample)
KR (2) KR102310899B1 (enExample)
CN (2) CN107002082B (enExample)
AU (3) AU2015345006B2 (enExample)
BR (1) BR112017006201B1 (enExample)
CA (2) CA2964834C (enExample)
CL (2) CL2017001233A1 (enExample)
CY (1) CY1121110T1 (enExample)
DK (1) DK3218488T3 (enExample)
ES (1) ES2705066T3 (enExample)
HU (1) HUE041793T2 (enExample)
IL (2) IL251565B (enExample)
MX (2) MX2017006369A (enExample)
MY (1) MY181404A (enExample)
PL (1) PL3218488T3 (enExample)
PT (1) PT3218488T (enExample)
RU (1) RU2717454C2 (enExample)
SG (1) SG11201703127SA (enExample)
TR (1) TR201900844T4 (enExample)
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EP3020813A1 (en) * 2014-11-16 2016-05-18 Neurovision Pharma GmbH Antisense-oligonucleotides as inhibitors of TGF-R signaling
WO2019010226A1 (en) * 2017-07-03 2019-01-10 The Regents Of The University Of California CHEMICALLY MODIFIED MICROARN-214 ANTISENS AND USE THEREOF FOR THE TREATMENT OF HEMORRHAGIC RECTOCOLITE AND PROCTITE
CA3081456A1 (en) * 2017-11-01 2019-05-09 Editas Medicine, Inc. Methods, compositions and components for crispr-cas9 editing of tgfbr2 in t cells for immunotherapy
CN111448316B (zh) * 2017-12-22 2025-02-14 罗氏创新中心哥本哈根有限公司 新的硫代亚磷酰胺
CN111448317B (zh) * 2017-12-22 2025-07-04 罗氏创新中心哥本哈根有限公司 包含二硫代磷酸酯核苷间键的缺口聚物寡核苷酸
US20200339982A1 (en) * 2017-12-22 2020-10-29 Roche Innovation Center Copenhagen A/S Oligonucleotides comprising a phosphorodithioate internucleoside linkage
CN118127019A (zh) 2018-05-22 2024-06-04 Ionis制药公司 Apol1表达的调节剂
CA3098267A1 (en) * 2018-07-31 2020-02-06 Roche Innovation Center Copenhagen A/S Oligonucleotides comprising a phosphorotrithioate internucleoside linkage
BR112021001756A2 (pt) * 2018-07-31 2021-05-11 Roche Innovation Center Copenhagen A/S oligonucleotídeos, oligonucleotídeo gapmer, sal farmaceuticamente aceitável, conjugado, composição farmacêutica, usos de um oligonucleotídeo, método para o tratamento ou profilaxia de uma doença, processo para a fabricação de um oligonucleotídeo e invenção
MX2021009950A (es) * 2019-02-20 2021-09-21 Roche Innovation Ct Copenhagen As Oligonucleotidos gapmeros de fosfonoacetato.
EP4237436A4 (en) * 2020-10-29 2025-09-10 Garcia Blanco Mariano A SOLUBLE INTERLEUKIN-7 RECEPTOR (SIL7R) MODULATION THERAPY FOR CANCERS
CN114588160A (zh) * 2020-12-07 2022-06-07 四川大学华西医院 具有抗肺纤维化作用的次黄碱衍生物
CN113992687B (zh) * 2021-12-28 2022-04-08 浙江宇视科技有限公司 智能业务集群调度方法、装置、电子设备及存储介质
TW202442689A (zh) 2023-03-03 2024-11-01 美商亞森諾生物科學公司 靶向ｐｓｍａ及ｃａ９之系統
WO2025254160A1 (ja) * 2024-06-05 2025-12-11 湧永製薬株式会社 ＴＧＦ－βシグナル阻害剤又は抗線維化剤のスクリーニング方法

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