ES2705066T3 - Oligonucleótidos antisentido como inhibidores de la señalización TGF-R - Google Patents

Oligonucleótidos antisentido como inhibidores de la señalización TGF-R Download PDF

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Publication number
ES2705066T3
ES2705066T3 ES15797640T ES15797640T ES2705066T3 ES 2705066 T3 ES2705066 T3 ES 2705066T3 ES 15797640 T ES15797640 T ES 15797640T ES 15797640 T ES15797640 T ES 15797640T ES 2705066 T3 ES2705066 T3 ES 2705066T3
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seq
lna
tgf
antisense oligonucleotide
nucleotides
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Spanish (es)
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Markus Hossbach
Monika Krampert
Hans-Lothar Arth
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Neurovision Pharma GmbH
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Neurovision Pharma GmbH
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ES15797640T 2014-11-16 2015-11-16 Oligonucleótidos antisentido como inhibidores de la señalización TGF-R Active ES2705066T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14193368.9A EP3020813A1 (en) 2014-11-16 2014-11-16 Antisense-oligonucleotides as inhibitors of TGF-R signaling
PCT/EP2015/076730 WO2016075339A1 (en) 2014-11-16 2015-11-16 Antisense-oligonucleotides as inhibitors of tgf-r signaling

Publications (1)

Publication Number Publication Date
ES2705066T3 true ES2705066T3 (es) 2019-03-21

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ES15797640T Active ES2705066T3 (es) 2014-11-16 2015-11-16 Oligonucleótidos antisentido como inhibidores de la señalización TGF-R

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US (4) US11213541B2 (enExample)
EP (3) EP3020813A1 (enExample)
JP (2) JP6832285B2 (enExample)
KR (2) KR102310899B1 (enExample)
CN (2) CN107002082B (enExample)
AU (3) AU2015345006B2 (enExample)
BR (1) BR112017006201B1 (enExample)
CA (2) CA3201845C (enExample)
CL (2) CL2017001233A1 (enExample)
CY (1) CY1121110T1 (enExample)
DK (1) DK3218488T3 (enExample)
ES (1) ES2705066T3 (enExample)
HU (1) HUE041793T2 (enExample)
IL (2) IL251565B (enExample)
MX (2) MX2017006369A (enExample)
MY (1) MY181404A (enExample)
PL (1) PL3218488T3 (enExample)
PT (1) PT3218488T (enExample)
RU (1) RU2717454C2 (enExample)
SG (1) SG11201703127SA (enExample)
TR (1) TR201900844T4 (enExample)
WO (1) WO2016075339A1 (enExample)

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EP3020813A1 (en) * 2014-11-16 2016-05-18 Neurovision Pharma GmbH Antisense-oligonucleotides as inhibitors of TGF-R signaling
WO2019010226A1 (en) * 2017-07-03 2019-01-10 The Regents Of The University Of California CHEMICALLY MODIFIED MICROARN-214 ANTISENS AND USE THEREOF FOR THE TREATMENT OF HEMORRHAGIC RECTOCOLITE AND PROCTITE
US20230061455A1 (en) * 2017-11-01 2023-03-02 Editas Medicine, Inc. Methods, compositions and components for crispr-cas9 editing of tgfbr2 in t cells for immunotherapy
CN111757936B (zh) * 2017-12-22 2025-07-04 罗氏创新中心哥本哈根有限公司 包含二硫代磷酸酯核苷间连接的寡核苷酸
US20200332289A1 (en) * 2017-12-22 2020-10-22 Roche Innovation Center Copenhagen A/S Gapmer oligonucleotides comprising a phosphorodithioate internucleoside linkage
US11597926B2 (en) * 2017-12-22 2023-03-07 Roche Innovation Center Copenhagen A/S Thiophosphoramidites
MY200352A (en) 2018-05-22 2023-12-21 Ionis Pharmaceuticals Inc Modulators of apol1 expression
CN112513060B (zh) * 2018-07-31 2024-08-06 罗氏创新中心哥本哈根有限公司 包含三硫代磷酸酯核苷间键的寡核苷酸
US20210221837A1 (en) * 2018-07-31 2021-07-22 Roche Innovation Center Copenhagen A/S Oligonucleotides comprising a phosphorotrithioate internucleoside linkage
CN113490742A (zh) * 2019-02-20 2021-10-08 罗氏创新中心哥本哈根有限公司 膦酰基乙酸酯缺口聚物寡核苷酸
EP4237436A4 (en) * 2020-10-29 2025-09-10 Garcia Blanco Mariano A SOLUBLE INTERLEUKIN-7 RECEPTOR (SIL7R) MODULATION THERAPY FOR CANCERS
CN114588160A (zh) * 2020-12-07 2022-06-07 四川大学华西医院 具有抗肺纤维化作用的次黄碱衍生物
CN113992687B (zh) * 2021-12-28 2022-04-08 浙江宇视科技有限公司 智能业务集群调度方法、装置、电子设备及存储介质
TW202442689A (zh) 2023-03-03 2024-11-01 美商亞森諾生物科學公司 靶向ｐｓｍａ及ｃａ９之系統

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