MY146017A - Antibodies that bind human interleukin-18 and methods of making and using - Google Patents
Antibodies that bind human interleukin-18 and methods of making and usingInfo
- Publication number
- MY146017A MY146017A MYPI20010574A MYPI20010574A MY146017A MY 146017 A MY146017 A MY 146017A MY PI20010574 A MYPI20010574 A MY PI20010574A MY PI20010574 A MYPI20010574 A MY PI20010574A MY 146017 A MY146017 A MY 146017A
- Authority
- MY
- Malaysia
- Prior art keywords
- antibodies
- hil
- making
- activity
- human
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18160800P | 2000-02-10 | 2000-02-10 |
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| MY146017A true MY146017A (en) | 2012-06-15 |
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| MYPI20010574A MY146017A (en) | 2000-02-10 | 2001-02-09 | Antibodies that bind human interleukin-18 and methods of making and using |
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| EP1761552B1 (en) * | 2004-06-29 | 2008-09-17 | Ares Trading S.A. | Process for the purification of il-18 binding protein |
| AU2005264453B2 (en) * | 2004-07-16 | 2011-07-14 | Atsuo Sekiyama | IL-18 receptor antagonist and pharmaceutical composition containing the antagonist |
| EP2161032B1 (en) * | 2004-08-20 | 2011-09-28 | GlaxoSmithKline LLC | Healing of wounds by administering human IL-18 |
| EP1885753B1 (en) * | 2005-06-03 | 2011-07-27 | Ares Trading S.A. | Production of recombinant Il-18 binding protein |
| US7612181B2 (en) * | 2005-08-19 | 2009-11-03 | Abbott Laboratories | Dual variable domain immunoglobulin and uses thereof |
| WO2007117577A2 (en) * | 2006-04-07 | 2007-10-18 | Regeneron Pharmaceuticals, Inc. | High affinity human antibodies to human il-18 receptor |
| PE20090190A1 (es) * | 2007-03-23 | 2009-03-22 | Smithkline Beecham Corp | Combinacion de anticuerpos anti-cd20 y polipeptidos de il-18 |
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2001
- 2001-02-09 EP EP01909010A patent/EP1257585A2/en not_active Withdrawn
- 2001-02-09 KR KR1020027010336A patent/KR100951067B1/ko not_active Expired - Fee Related
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- 2001-02-09 BR BR0108188-8A patent/BR0108188A/pt not_active IP Right Cessation
- 2001-02-09 EP EP10183844A patent/EP2360184A3/en not_active Withdrawn
- 2001-02-09 SK SK1294-2002A patent/SK12942002A3/sk not_active Application Discontinuation
- 2001-02-09 CA CA002399148A patent/CA2399148A1/en not_active Abandoned
- 2001-02-09 MX MXPA02007756A patent/MXPA02007756A/es active IP Right Grant
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- 2001-02-09 TW TW090102913A patent/TWI335336B/zh not_active IP Right Cessation
- 2001-02-09 US US09/780,035 patent/US7767207B2/en not_active Expired - Fee Related
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- 2001-02-09 CN CN2011100884013A patent/CN102206277A/zh active Pending
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- 2001-02-09 NZ NZ520392A patent/NZ520392A/en not_active IP Right Cessation
- 2001-02-09 EP EP10185308A patent/EP2338515A3/en not_active Withdrawn
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- 2001-02-09 AU AU2001236807A patent/AU2001236807A1/en not_active Abandoned
- 2001-02-09 KR KR1020117006339A patent/KR20110032012A/ko not_active Ceased
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2002
- 2002-08-06 ZA ZA200206266A patent/ZA200206266B/xx unknown
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2006
- 2006-12-18 AU AU2006252098A patent/AU2006252098B9/en not_active Ceased
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2010
- 2010-05-24 US US12/786,095 patent/US20110008357A1/en not_active Abandoned
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