MY139601A - Thiadiazoledioxides and thiadiazoleoxides as cxc-and cc-chemokine receptor ligands - Google Patents
Thiadiazoledioxides and thiadiazoleoxides as cxc-and cc-chemokine receptor ligandsInfo
- Publication number
- MY139601A MY139601A MYPI20033827A MYPI20033827A MY139601A MY 139601 A MY139601 A MY 139601A MY PI20033827 A MYPI20033827 A MY PI20033827A MY PI20033827 A MYPI20033827 A MY PI20033827A MY 139601 A MY139601 A MY 139601A
- Authority
- MY
- Malaysia
- Prior art keywords
- aryl
- thiadiazoleoxides
- thiadiazoledioxides
- cxc
- substituent
- Prior art date
Links
- 108091008927 CC chemokine receptors Proteins 0.000 title 1
- 102000005674 CCR Receptors Human genes 0.000 title 1
- 108091008928 CXC chemokine receptors Proteins 0.000 title 1
- 102000054900 CXCR Receptors Human genes 0.000 title 1
- 239000003446 ligand Substances 0.000 title 1
- LKHDXIBHVSGUHN-UHFFFAOYSA-N thiadiazole 1,1-dioxide Chemical class O=S1(=O)C=CN=N1 LKHDXIBHVSGUHN-UHFFFAOYSA-N 0.000 title 1
- XWMXMWHHTIEXRE-UHFFFAOYSA-N thiadiazole 1-oxide Chemical class O=S1C=CN=N1 XWMXMWHHTIEXRE-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- -1 AMINO Chemical class 0.000 abstract 1
- 102000019034 Chemokines Human genes 0.000 abstract 1
- 108010012236 Chemokines Proteins 0.000 abstract 1
- 206010065390 Inflammatory pain Diseases 0.000 abstract 1
- 208000019693 Lung disease Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 208000002193 Pain Diseases 0.000 abstract 1
- 206010063837 Reperfusion injury Diseases 0.000 abstract 1
- 208000006011 Stroke Diseases 0.000 abstract 1
- 230000001154 acute effect Effects 0.000 abstract 1
- 208000005298 acute pain Diseases 0.000 abstract 1
- 230000033115 angiogenesis Effects 0.000 abstract 1
- 230000002491 angiogenic effect Effects 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 230000000747 cardiac effect Effects 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 201000006417 multiple sclerosis Diseases 0.000 abstract 1
- 208000004296 neuralgia Diseases 0.000 abstract 1
- 208000021722 neuropathic pain Diseases 0.000 abstract 1
- 201000008482 osteoarthritis Diseases 0.000 abstract 1
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/10—1,2,5-Thiadiazoles; Hydrogenated 1,2,5-thiadiazoles
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- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41737102P | 2002-10-09 | 2002-10-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY139601A true MY139601A (en) | 2009-10-30 |
Family
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Family Applications (1)
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| MYPI20033827A MY139601A (en) | 2002-10-09 | 2003-10-07 | Thiadiazoledioxides and thiadiazoleoxides as cxc-and cc-chemokine receptor ligands |
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| JP (2) | JP4664074B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN1720240B (cg-RX-API-DMAC7.html) |
| AR (1) | AR043052A1 (cg-RX-API-DMAC7.html) |
| AT (1) | ATE422203T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2003288922A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2501535A1 (cg-RX-API-DMAC7.html) |
| DE (1) | DE60326080D1 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2321186T3 (cg-RX-API-DMAC7.html) |
| MX (1) | MXPA05003867A (cg-RX-API-DMAC7.html) |
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| PE (1) | PE20040570A1 (cg-RX-API-DMAC7.html) |
| TW (1) | TW200413342A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2004033440A1 (cg-RX-API-DMAC7.html) |
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| US20040106794A1 (en) * | 2001-04-16 | 2004-06-03 | Schering Corporation | 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands |
| WO2003080053A1 (en) * | 2002-03-18 | 2003-10-02 | Schering Corporation | Combination treatments for chemokine-mediated diseases |
| DE60326080D1 (en) | 2002-10-09 | 2009-03-19 | Schering Corp | Thiadiazoldioxide und thiadiazoloxide als cxc- und cc-chemokinrezeptor liganden |
| WO2004037804A1 (en) * | 2002-10-22 | 2004-05-06 | Oscotec Inc. | Furan derivatives for preventing and curing osteoporosis and pharmaceutical compositions containing the same |
| AR047759A1 (es) * | 2003-09-26 | 2006-02-22 | Vertex Pharma | Derivados de fenil - piperazina como moduladores de receptores muscarnicos |
| ATE406356T1 (de) * | 2003-12-19 | 2008-09-15 | Schering Corp | Thiadiazole als cxc- und cc- chemokinrezeptorliganden |
| TW200530231A (en) * | 2003-12-22 | 2005-09-16 | Schering Corp | Isothiazole dioxides as CXC-and CC-chemokine receptor ligands |
| US7326729B2 (en) * | 2004-05-12 | 2008-02-05 | Schering Corporation | CXCR1 and CXCR2 chemokine antagonists |
| AR049384A1 (es) | 2004-05-24 | 2006-07-26 | Glaxo Group Ltd | Derivados de purina |
| JP2008500372A (ja) * | 2004-05-26 | 2008-01-10 | カリフォルニア インスティテュート オブ テクノロジー | ニューロン成長の低分子刺激物質 |
| EA200700117A1 (ru) | 2004-06-24 | 2007-06-29 | Инсайт Корпорейшн | N-замещенные пиперидины и их применение в качестве фармацевтических препаратов |
| GB0510140D0 (en) | 2005-05-18 | 2005-06-22 | Addex Pharmaceuticals Sa | Novel compounds B2 |
| CA2613607A1 (en) * | 2005-06-29 | 2007-01-04 | Schering Corporation | Di-substituted oxadiazoles as cxc-chemokine receptor ligands |
| ES2353401T3 (es) * | 2005-06-29 | 2011-03-01 | Schering Corporation | Oxidiazolopirazinas y tiadiazolopirazinas 5,6-di-sustituidas como ligandos del receptor de cxc-quimiocina. |
| GB0514809D0 (en) | 2005-07-19 | 2005-08-24 | Glaxo Group Ltd | Compounds |
| WO2008005570A1 (en) * | 2006-07-07 | 2008-01-10 | Schering Corporation | 3,4-di-substituted cyclobutene-1,2-diones as cxc-chemokine receptor ligands |
| WO2010050445A1 (ja) * | 2008-10-27 | 2010-05-06 | 武田薬品工業株式会社 | 二環性化合物 |
| EP2593447B1 (de) | 2010-07-15 | 2016-08-17 | Bayer Intellectual Property GmbH | 3-pyridyl-heteroarylcarboxamidverbindungen als schädlingsbekämpfungsmittel |
| US9670277B2 (en) | 2011-02-24 | 2017-06-06 | The Schepens Eye Reasearch Institute, Inc. | Compositions and methods for treating inflammatory conditions of the ocular surface |
| US8865723B2 (en) | 2012-10-25 | 2014-10-21 | Tetra Discovery Partners Llc | Selective PDE4 B inhibition and improvement in cognition in subjects with brain injury |
| US10227370B2 (en) | 2013-08-02 | 2019-03-12 | California Institute Of Technology | Heparan sulfate/heparin mimetics with anti-chemokine and anti-inflammatory activity |
| US9770461B2 (en) | 2013-08-02 | 2017-09-26 | California Institute Of Technology | Tailored glycopolymers as anticoagulant heparin mimetics |
| CN103724304B (zh) * | 2013-12-24 | 2016-08-17 | 定陶县友帮化工有限公司 | 5-溴苯并呋喃的制备方法 |
| CN103787956B (zh) * | 2014-01-20 | 2016-03-30 | 上海医药工业研究院 | 用于制备泊马度胺的中间体的制备方法 |
| US9763992B2 (en) | 2014-02-13 | 2017-09-19 | Father Flanagan's Boys' Home | Treatment of noise induced hearing loss |
| WO2018073248A1 (en) | 2016-10-17 | 2018-04-26 | Icm (Institut Du Cerveau Et De La Moelle Épinière) | Prognosis of demyelinating diseases patients and treatment thereof |
| US20180193003A1 (en) | 2016-12-07 | 2018-07-12 | Progenity Inc. | Gastrointestinal tract detection methods, devices and systems |
| WO2018112264A1 (en) | 2016-12-14 | 2018-06-21 | Progenity Inc. | Treatment of a disease of the gastrointestinal tract with a chemokine/chemokine receptor inhibitor |
| WO2018236738A1 (en) | 2017-06-20 | 2018-12-27 | Dow Global Technologies Llc | Biaryl phenoxy group iv transition metal catalysts for olefin polymerization |
| BR112021003956A2 (pt) * | 2018-09-21 | 2021-05-25 | Pfizer Inc. | dioxociclobutenilamino-3-hidróxi-picolinamidas n-substituídas úteis como inibidores de ccr6 |
| JP7482866B2 (ja) | 2018-11-19 | 2024-05-14 | ビオラ・セラピューティクス・インコーポレイテッド | 生物学的治療薬による疾患処置方法およびデバイス |
| CN109970588B (zh) * | 2019-03-14 | 2024-03-08 | 武汉南望环保技术研究有限责任公司 | 一种无毒耐久型防污涂料及其制备方法 |
| CN121197633A (zh) | 2019-12-13 | 2025-12-26 | 比特比德科有限责任公司 | 用于将治疗剂递送至胃肠道的可摄取装置 |
| BG67727B1 (bg) | 2022-04-04 | 2025-05-15 | "Мицар Иновейшън" ООД | Пан-хемокинови антагонисти за използване при превенция и намаляване на метастази при рак |
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-
2003
- 2003-10-07 DE DE60326080T patent/DE60326080D1/de not_active Expired - Lifetime
- 2003-10-07 CA CA002501535A patent/CA2501535A1/en not_active Abandoned
- 2003-10-07 CN CN2003801051392A patent/CN1720240B/zh not_active Expired - Fee Related
- 2003-10-07 AU AU2003288922A patent/AU2003288922A1/en not_active Abandoned
- 2003-10-07 PE PE2003001019A patent/PE20040570A1/es not_active Application Discontinuation
- 2003-10-07 EP EP03781311A patent/EP1551818B1/en not_active Expired - Lifetime
- 2003-10-07 ES ES03781311T patent/ES2321186T3/es not_active Expired - Lifetime
- 2003-10-07 MY MYPI20033827A patent/MY139601A/en unknown
- 2003-10-07 WO PCT/US2003/031707 patent/WO2004033440A1/en not_active Ceased
- 2003-10-07 AT AT03781311T patent/ATE422203T1/de not_active IP Right Cessation
- 2003-10-07 MX MXPA05003867A patent/MXPA05003867A/es not_active Application Discontinuation
- 2003-10-07 JP JP2004543449A patent/JP4664074B2/ja not_active Expired - Fee Related
- 2003-10-07 US US10/680,393 patent/US20040186142A1/en not_active Abandoned
- 2003-10-08 AR ARP030103663A patent/AR043052A1/es unknown
- 2003-10-08 TW TW092127957A patent/TW200413342A/zh unknown
-
2007
- 2007-01-09 US US11/651,128 patent/US7691856B2/en not_active Expired - Fee Related
-
2010
- 2010-09-02 JP JP2010197184A patent/JP2010270151A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| ES2321186T3 (es) | 2009-06-03 |
| MXPA05003867A (es) | 2005-11-23 |
| JP2010270151A (ja) | 2010-12-02 |
| TW200413342A (en) | 2004-08-01 |
| CN1720240A (zh) | 2006-01-11 |
| CA2501535A1 (en) | 2004-04-22 |
| CN1720240B (zh) | 2010-10-27 |
| DE60326080D1 (en) | 2009-03-19 |
| JP4664074B2 (ja) | 2011-04-06 |
| EP1551818A1 (en) | 2005-07-13 |
| EP1551818B1 (en) | 2009-02-04 |
| US7691856B2 (en) | 2010-04-06 |
| HK1072432A1 (en) | 2005-10-28 |
| PE20040570A1 (es) | 2004-08-30 |
| US20070264230A1 (en) | 2007-11-15 |
| ATE422203T1 (de) | 2009-02-15 |
| AR043052A1 (es) | 2005-07-13 |
| WO2004033440A1 (en) | 2004-04-22 |
| WO2004033440A8 (en) | 2005-06-02 |
| US20040186142A1 (en) | 2004-09-23 |
| AU2003288922A1 (en) | 2004-05-04 |
| JP2006508079A (ja) | 2006-03-09 |
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