MY124273A - Methods for separating a tocotrienol from a tocol-containing mixture and compositions thereof. - Google Patents
Methods for separating a tocotrienol from a tocol-containing mixture and compositions thereof.Info
- Publication number
- MY124273A MY124273A MYPI99000291A MYPI9900291A MY124273A MY 124273 A MY124273 A MY 124273A MY PI99000291 A MYPI99000291 A MY PI99000291A MY PI9900291 A MYPI9900291 A MY PI9900291A MY 124273 A MY124273 A MY 124273A
- Authority
- MY
- Malaysia
- Prior art keywords
- tocotrienol
- tocol
- tocol admixture
- fatty acid
- tocopherol
- Prior art date
Links
- DFUSDJMZWQVQSF-XLGIIRLISA-N (2r)-2-methyl-2-[(4r,8r)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-ol Chemical compound OC1=CC=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1 DFUSDJMZWQVQSF-XLGIIRLISA-N 0.000 title abstract 11
- GJJVAFUKOBZPCB-UHFFFAOYSA-N 2-methyl-2-(4,8,12-trimethyltrideca-3,7,11-trienyl)-3,4-dihydrochromen-6-ol Chemical compound OC1=CC=C2OC(CCC=C(C)CCC=C(C)CCC=C(C)C)(C)CCC2=C1 GJJVAFUKOBZPCB-UHFFFAOYSA-N 0.000 title abstract 9
- 229930003802 tocotrienol Natural products 0.000 title abstract 9
- 239000011731 tocotrienol Substances 0.000 title abstract 9
- 235000019148 tocotrienols Nutrition 0.000 title abstract 9
- 238000000034 method Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 6
- 229930195729 fatty acid Natural products 0.000 abstract 6
- 239000000194 fatty acid Substances 0.000 abstract 6
- 150000004665 fatty acids Chemical class 0.000 abstract 6
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 abstract 5
- 229930003799 tocopherol Natural products 0.000 abstract 5
- 239000011732 tocopherol Substances 0.000 abstract 5
- 229960001295 tocopherol Drugs 0.000 abstract 5
- 235000010384 tocopherol Nutrition 0.000 abstract 5
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 abstract 5
- 238000000605 extraction Methods 0.000 abstract 4
- 239000002904 solvent Substances 0.000 abstract 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
- C07D311/72—3,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Fats And Perfumes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7296398P | 1998-01-29 | 1998-01-29 | |
| US7296298P | 1998-01-29 | 1998-01-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY124273A true MY124273A (en) | 2006-06-30 |
Family
ID=26753962
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI99000291A MY124273A (en) | 1998-01-29 | 1999-01-28 | Methods for separating a tocotrienol from a tocol-containing mixture and compositions thereof. |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US6159347A (cg-RX-API-DMAC10.html) |
| EP (2) | EP1051412B1 (cg-RX-API-DMAC10.html) |
| JP (2) | JP2002501915A (cg-RX-API-DMAC10.html) |
| CN (2) | CN1221542C (cg-RX-API-DMAC10.html) |
| BR (2) | BR9908141A (cg-RX-API-DMAC10.html) |
| ES (2) | ES2178384T3 (cg-RX-API-DMAC10.html) |
| MY (1) | MY124273A (cg-RX-API-DMAC10.html) |
| WO (2) | WO1999038860A1 (cg-RX-API-DMAC10.html) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6706898B2 (en) | 1998-01-29 | 2004-03-16 | Archer-Daniels-Midland Company | Methods for separating a tocopherol from a tocopherol-containing mixture |
| AU5041400A (en) | 1999-05-24 | 2000-12-12 | America River Nutrition, Inc. | Tocotrienols and geranylgeraniol from LTiGTbixa orellanaLT/iGT byproducts |
| US6395915B1 (en) | 1999-09-10 | 2002-05-28 | Technikrom, Inc. | Method for producing purified tocotrienols and tocopherols using liquid chromatography |
| US6706474B1 (en) * | 2000-06-27 | 2004-03-16 | Board Of Trustees Of The University Of Illinois | Nucleic acid enzyme biosensors for ions |
| US6838104B2 (en) * | 2000-12-20 | 2005-01-04 | Archer Daniels Midland Company | Process for the production of tocotrienols |
| US6867308B2 (en) | 2001-09-19 | 2005-03-15 | Archer-Daniels-Midland Company | Process for separation of tocopherols |
| US6890719B2 (en) | 2002-05-10 | 2005-05-10 | The Board Of Trustess Of The University Of Illinois | Fluorescence based biosensor |
| US7461048B2 (en) * | 2003-07-21 | 2008-12-02 | Aureon Laboratories, Inc. | Systems and methods for treating, diagnosing and predicting the occurrence of a medical condition |
| KR20060134913A (ko) * | 2003-09-10 | 2006-12-28 | 이스트만 케미칼 컴파니 | 피토리피드 조성물의 회수 방법 |
| US7416756B2 (en) * | 2003-09-10 | 2008-08-26 | Eastman Chemical Company | Process for the recovery of a phytolipid composition |
| WO2005035491A2 (en) * | 2003-10-10 | 2005-04-21 | Yasoo Health, Inc. | PROCESS FOR SYNTHESIZING d-TOCOTRIENOLS FROM 2- VINYLCHROMANE COMPOUND |
| MY173044A (en) * | 2003-11-19 | 2019-12-20 | Carotech Bhd | Recovery of phytonutriens from oils |
| EA035619B1 (ru) | 2005-06-01 | 2020-07-16 | ПиТиСи ТЕРАПЬЮТИКС, ИНК. | Композиции для использования в способе лечения митохондриальных нарушений |
| US7892734B2 (en) * | 2005-08-11 | 2011-02-22 | The Board Of Trustees Of The University Of Illinois | Aptamer based colorimetric sensor systems |
| EP1986636B1 (en) | 2006-02-22 | 2013-04-24 | Edison Pharmaceuticals, Inc. | Phenol and 1,4-benzoquinone derivatives for use in the treatment of mitochondrial diseases |
| US7799554B2 (en) * | 2006-03-16 | 2010-09-21 | The Board Of Trustees Of The University Of Illinois | Lateral flow devices |
| US8415461B2 (en) * | 2007-01-19 | 2013-04-09 | The Board Of Trustees Of The University Of Illinois | Amphiphilic substances and functionalized lipid vesicles including the same |
| US8058415B2 (en) * | 2007-04-24 | 2011-11-15 | The Board Of Trustees Of The University Of Illinois | Aptamer- and nucleic acid enzyme-based systems for simultaneous detection of multiple analytes |
| KR101481197B1 (ko) * | 2007-05-24 | 2015-01-09 | 로더스 크로클란 비.브이. | 토코페롤 및 토코트리에놀을 함유하는 조성물의 제조방법 |
| WO2009012309A2 (en) * | 2007-07-16 | 2009-01-22 | The Board Of Trustees Of The University Of Illinois | Nucleic acid based fluorescent sensor for divalent copper ion detection |
| US8568690B2 (en) * | 2007-07-31 | 2013-10-29 | The Board Of Trustees Of The University Of Illinois | MRI contrast agents and high-throughput screening by MRI |
| WO2009045632A2 (en) | 2007-08-10 | 2009-04-09 | The Board Of Trustees Of The University Of Illinois | Nucleic acid based fluorescent sensor for mercury detection |
| US20090090894A1 (en) * | 2007-10-05 | 2009-04-09 | Bin Wang | Separation and extraction system |
| US20100105039A1 (en) * | 2008-06-03 | 2010-04-29 | Yi Lu | Label-free colorimetric detection |
| EP2344142B1 (en) | 2008-09-10 | 2024-06-26 | PTC Therapeutics, Inc. | Treatment of pervasive developmental disorders with redox-active therapeutics |
| US8062893B2 (en) | 2008-10-10 | 2011-11-22 | The Board Of Trustees Of The University Of Illinois | Fluorescent sensor for mercury |
| WO2010051277A1 (en) * | 2008-10-28 | 2010-05-06 | Edison Pharmaceuticals, Inc. | Process for the production of alpha-tocotrienol and derivatives |
| CA2777479C (en) | 2009-04-28 | 2017-10-17 | Ptc Therapeutics, Inc. | Treatment of leber's hereditary optic neuropathy and dominant optic atrophy with tocotrienol quinones |
| JP2012531411A (ja) | 2009-06-25 | 2012-12-10 | アンペア ライフ サイエンシーズ，インコーポレイテッド | トコトリエノールまたはトコトリエノール濃縮抽出物を用いた広汎性発達障害の処置 |
| US8815156B2 (en) | 2010-07-19 | 2014-08-26 | Andalyze, Inc. | Sensor housing and reagent chemistry |
| CA2842486C (en) | 2011-07-19 | 2022-09-06 | Edison Pharmaceuticals, Inc. | Methods for oxidation of alpha tocotrienol in the presence of non-alpha tocotrienols |
| EA201390236A1 (ru) | 2012-01-25 | 2014-10-30 | Асахи Касеи Кемикалз Корпорейшн | Способ разделения |
| EP2810940A1 (en) * | 2013-06-06 | 2014-12-10 | Sulzer Chemtech AG | A Process to Prepare A Tocopherol Concentrate |
| US9512098B1 (en) | 2014-02-03 | 2016-12-06 | Board Of Trustees Of The University Of Arkansas | Process of producing purified gamma- and delta-tocotrienols from tocol-rich oils or distillates |
| SG11201606162XA (en) | 2014-02-11 | 2016-08-30 | Evonik Membrane Extraction Technology Ltd | Method for producing vitamine e-enriched, especially tocotrienol-enriched, compositions from natural oils |
| JP7117241B2 (ja) | 2015-12-16 | 2022-08-12 | ピーティーシー セラピューティクス， インコーポレイテッド | 混合されたトコール組成物からアルファ－トコトリエノールを富化するための改良された方法 |
| EP3389646A1 (en) | 2015-12-17 | 2018-10-24 | BioElectron Technology Corporation | Flouroalkyl, flouroalkoxy, phenoxy, heteroaryloxy, alkoxy, and amine 1,4-benzoquinone derivatives for treatment of oxidative stress disorders |
| MY184673A (en) * | 2018-03-16 | 2021-04-15 | Palm Nutraceuticals Sdn Bhd | A process of preparing vitamin e concentrate |
| CN110251980B (zh) * | 2019-04-22 | 2021-03-23 | 中建安装集团有限公司 | 一种二恶烷水溶液中提纯优品级二恶烷的装置及方法 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2866797A (en) | 1954-11-01 | 1958-12-30 | Gen Mills Inc | Improved process of isolating sterols |
| US3153055A (en) * | 1962-03-20 | 1964-10-13 | Eastman Kodak Co | Process for separating tocopherols and sterols from deodorizer sludge and the like |
| US3335154A (en) * | 1963-06-04 | 1967-08-08 | Eastman Kodak Co | Separation of tocopherols and sterols from deodorizer sludge and the like |
| US4454329A (en) * | 1980-07-04 | 1984-06-12 | The Nisshin Oil Mills, Ltd. | Process for preparation of tocopherol concentrates |
| US4480108A (en) * | 1983-08-01 | 1984-10-30 | Eastman Kodak Company | Process for separation of tocopherol homologues |
| JPS6048981A (ja) | 1983-08-29 | 1985-03-16 | Showa Denko Kk | 高純度トコフェロ−ルの製造方法 |
| JPS60149582A (ja) | 1984-01-14 | 1985-08-07 | Mitsui Petrochem Ind Ltd | トコフエロ−ルの精製方法 |
| JPS60185776A (ja) | 1984-03-05 | 1985-09-21 | Riken Vitamin Co Ltd | トコフエロ−ルの精製濃縮法 |
| US4550183A (en) * | 1984-08-02 | 1985-10-29 | Henkel Corporation | Purification of tocopherols |
| EP0171009B1 (en) * | 1984-08-02 | 1991-05-22 | HENKEL CORPORATION (a Delaware corp.) | Purification of tocopherols by extraction |
| JPS6160619A (ja) * | 1984-08-31 | 1986-03-28 | Eisai Co Ltd | 分散性粉末 |
| JPS6193178A (ja) * | 1984-10-12 | 1986-05-12 | Agency Of Ind Science & Technol | トコトリエノ−ル類の分離方法 |
| JPS61151186A (ja) * | 1984-12-24 | 1986-07-09 | Nisshin Oil Mills Ltd:The | トコトリエノ−ル類およびトコフエロ−ル類の濃縮法 |
| DE3615029A1 (de) | 1985-05-06 | 1986-11-06 | Henkel Corp., Minneapolis, Minn. | Methanol-extraktion von tocopherol |
| AU618791B2 (en) * | 1988-03-16 | 1992-01-09 | Bioindustry Development Centre | Production of high concentration tocopherols and tocotrienols from palm oil by-product |
| JPH03127730A (ja) | 1989-10-11 | 1991-05-30 | Kikaku Nijiyuuichi:Kk | ビタミンｅの製造方法 |
| WO1991017985A1 (en) * | 1990-05-23 | 1991-11-28 | Lipogenics, Inc. | Processes for recovering tocotrienols, tocopherols and tocotrienol-like compounds |
| US5487817A (en) * | 1993-02-11 | 1996-01-30 | Hoffmann-La Roche Inc. | Process for tocopherols and sterols from natural sources |
| BR9407179A (pt) * | 1993-08-06 | 1996-09-17 | Henkel Corp | Processos de recuperação tocoferóis a partir de uma mistura gordurosa compreendida de ácidos graxos e tocoferóis de evaporação para a separação de alquil ésteres inferiores de ácido graxo de uma mistura que compreende adicionalmente tocoferóis e esteróis e de separação de um ou mais compostos de tocoferol de um ou mais compostos de esterol |
| US5512691A (en) * | 1994-11-07 | 1996-04-30 | Eastman Chemical Company | Process for the production of tocopherol concentrates |
| US5660691A (en) * | 1995-11-13 | 1997-08-26 | Eastman Chemical Company | Process for the production of tocotrienol/tocopherol blend concentrates |
| US5703252A (en) * | 1995-12-13 | 1997-12-30 | Henkel Corporation | Recovery of Tocopherols |
-
1999
- 1999-01-26 EP EP99904267A patent/EP1051412B1/en not_active Expired - Lifetime
- 1999-01-26 CN CNB998024449A patent/CN1221542C/zh not_active Expired - Fee Related
- 1999-01-26 WO PCT/US1999/001571 patent/WO1999038860A1/en not_active Ceased
- 1999-01-26 EP EP99904266A patent/EP1051411B1/en not_active Expired - Lifetime
- 1999-01-26 US US09/237,406 patent/US6159347A/en not_active Expired - Fee Related
- 1999-01-26 JP JP2000529327A patent/JP2002501915A/ja active Pending
- 1999-01-26 JP JP2000529328A patent/JP2002501916A/ja active Pending
- 1999-01-26 BR BR9908141-5A patent/BR9908141A/pt not_active IP Right Cessation
- 1999-01-26 ES ES99904266T patent/ES2178384T3/es not_active Expired - Lifetime
- 1999-01-26 ES ES99904267T patent/ES2207931T3/es not_active Expired - Lifetime
- 1999-01-26 WO PCT/US1999/001570 patent/WO1999038859A1/en not_active Ceased
- 1999-01-26 US US09/237,384 patent/US6224717B1/en not_active Expired - Fee Related
- 1999-01-26 BR BR9907278-5A patent/BR9907278A/pt not_active IP Right Cessation
- 1999-01-26 CN CN99802443A patent/CN1295568A/zh active Pending
- 1999-01-28 MY MYPI99000291A patent/MY124273A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1314901A (zh) | 2001-09-26 |
| JP2002501915A (ja) | 2002-01-22 |
| ES2207931T3 (es) | 2004-06-01 |
| JP2002501916A (ja) | 2002-01-22 |
| EP1051411B1 (en) | 2002-08-28 |
| EP1051411A1 (en) | 2000-11-15 |
| WO1999038859A1 (en) | 1999-08-05 |
| CN1221542C (zh) | 2005-10-05 |
| CN1295568A (zh) | 2001-05-16 |
| BR9908141A (pt) | 2000-11-28 |
| US6224717B1 (en) | 2001-05-01 |
| ES2178384T3 (es) | 2002-12-16 |
| BR9907278A (pt) | 2000-10-24 |
| WO1999038860A1 (en) | 1999-08-05 |
| US6159347A (en) | 2000-12-12 |
| EP1051412A1 (en) | 2000-11-15 |
| EP1051412B1 (en) | 2003-09-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR9907278A (pt) | Processos para separar um tocotrienol de uma primeira mistura de tocol, e, composição | |
| CA2143441C (en) | Recovery of tocopherol and sterol | |
| WO2000043095A3 (en) | Methods for separating a tocopherol from a tocopherol-containing mixture and compositions thereof | |
| US5660691A (en) | Process for the production of tocotrienol/tocopherol blend concentrates | |
| JP2002501916A5 (cg-RX-API-DMAC10.html) | ||
| EP1689353B1 (en) | Recovery of phytonutrients from oils | |
| EP0992500A3 (en) | Recovery of tocopherols | |
| US5703252A (en) | Recovery of Tocopherols | |
| CA1276645C (en) | Purification of tocopherols | |
| CA2492831C (en) | Color-stable, low impurity tocopherol compositions and processes for preparing the same | |
| TH40846A (th) | วิธีการแยกโทโคไตรอีนอลจากสารผสม ซึ่งมีโทคอลและองค์ประกอบของสิ่งเหล่านั้น | |
| TH40845A (th) | วิธีการสำหรับการแยกโทคอลออกจากของผสมที่มีโทคอล | |
| EP1305022A1 (en) | Processes for the purification of tocopherol and/or sterol compounds and compositions containing orthoborate ester mixtures | |
| GB774855A (en) | Improvements in or relating to the recovery of tocopherols from deodorizer sludges | |
| RU1771474C (ru) | Способ концентрировани природных токоферолов из дистиллатов растительного масла | |
| JPS5934191B2 (ja) | 植物油脂よりトコフェロ−ル類及びトコトリエノ−ル類の濃縮法 | |
| TH40846A3 (th) | วิธีการแยกโทโคไตรอีนอลจากสารผสม ซึ่งมีโทคอลและองค์ประกอบของสิ่งเหล่านั้น | |
| KR920004554A (ko) | 대두유 탈취 증류분으로부터 스테롤 및 토코페롤을 분리, 농축하는 방법 | |
| KR910018370A (ko) | 천연토코페롤류의 추출 방법 | |
| MY153188A (en) | Recovery of minor components and refining of vegetable oils and fats. | |
| JPS57154181A (en) | Preparation of concentrate of tocopherols | |
| JPS6157309B2 (cg-RX-API-DMAC10.html) | ||
| WO1999043316A1 (en) | Production of coenzyme q | |
| KR960031583A (ko) | 신규의 c_22 지방산락톤 유도체 및 그 추출방법 | |
| TH74291A (th) | การสกัดแยกไฟโตนิวเทรียนท์ออกจากน้ำมัน |