MXPA06014896A - Medicion no invasiva de la glucosa. - Google Patents
Medicion no invasiva de la glucosa.Info
- Publication number
- MXPA06014896A MXPA06014896A MXPA06014896A MXPA06014896A MXPA06014896A MX PA06014896 A MXPA06014896 A MX PA06014896A MX PA06014896 A MXPA06014896 A MX PA06014896A MX PA06014896 A MXPA06014896 A MX PA06014896A MX PA06014896 A MXPA06014896 A MX PA06014896A
- Authority
- MX
- Mexico
- Prior art keywords
- glucose
- patch
- skin
- sweat
- detector
- Prior art date
Links
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- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
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- A—HUMAN NECESSITIES
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- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
- A61B5/14517—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for sweat
- A61B5/14521—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for sweat using means for promoting sweat production, e.g. heating the skin
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- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/54—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
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- A—HUMAN NECESSITIES
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- A61B2562/02—Details of sensors specially adapted for in-vivo measurements
- A61B2562/0295—Strip shaped analyte sensors for apparatus classified in A61B5/145 or A61B5/157
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
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| US58541404P | 2004-07-01 | 2004-07-01 | |
| PCT/US2005/022139 WO2006007472A2 (en) | 2004-07-01 | 2005-06-22 | Non-invasive glucose measurement |
Publications (1)
| Publication Number | Publication Date |
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| MXPA06014896A true MXPA06014896A (es) | 2007-08-20 |
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| MXPA06014896A MXPA06014896A (es) | 2004-07-01 | 2005-06-22 | Medicion no invasiva de la glucosa. |
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| EP (1) | EP1776035A2 (https=) |
| JP (2) | JP2008504881A (https=) |
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| CA (1) | CA2572313A1 (https=) |
| IL (1) | IL180034A0 (https=) |
| MX (1) | MXPA06014896A (https=) |
| WO (1) | WO2006007472A2 (https=) |
Families Citing this family (252)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8734339B2 (en) | 1996-12-16 | 2014-05-27 | Ip Holdings, Inc. | Electronic skin patch for real time monitoring of cardiac activity and personal health management |
| US6036924A (en) * | 1997-12-04 | 2000-03-14 | Hewlett-Packard Company | Cassette of lancet cartridges for sampling blood |
| US6391005B1 (en) | 1998-03-30 | 2002-05-21 | Agilent Technologies, Inc. | Apparatus and method for penetration with shaft having a sensor for sensing penetration depth |
| US8465425B2 (en) | 1998-04-30 | 2013-06-18 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US8346337B2 (en) | 1998-04-30 | 2013-01-01 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US8688188B2 (en) | 1998-04-30 | 2014-04-01 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US8480580B2 (en) | 1998-04-30 | 2013-07-09 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US6949816B2 (en) | 2003-04-21 | 2005-09-27 | Motorola, Inc. | Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same |
| US9066695B2 (en) | 1998-04-30 | 2015-06-30 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US6175752B1 (en) | 1998-04-30 | 2001-01-16 | Therasense, Inc. | Analyte monitoring device and methods of use |
| US8974386B2 (en) | 1998-04-30 | 2015-03-10 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US8715177B2 (en) | 2000-10-06 | 2014-05-06 | Ip Holdings, Inc. | Intelligent drug delivery appliance |
| US8641644B2 (en) | 2000-11-21 | 2014-02-04 | Sanofi-Aventis Deutschland Gmbh | Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means |
| DE10057832C1 (de) * | 2000-11-21 | 2002-02-21 | Hartmann Paul Ag | Blutanalysegerät |
| US6560471B1 (en) * | 2001-01-02 | 2003-05-06 | Therasense, Inc. | Analyte monitoring device and methods of use |
| EP1397068A2 (en) | 2001-04-02 | 2004-03-17 | Therasense, Inc. | Blood glucose tracking apparatus and methods |
| US6748250B1 (en) * | 2001-04-27 | 2004-06-08 | Medoptix, Inc. | Method and system of monitoring a patient |
| US20090137888A9 (en) * | 2001-04-27 | 2009-05-28 | Berman Herbert L | System for monitoring of patients |
| US7025774B2 (en) | 2001-06-12 | 2006-04-11 | Pelikan Technologies, Inc. | Tissue penetration device |
| DE60234598D1 (de) | 2001-06-12 | 2010-01-14 | Pelikan Technologies Inc | Selbstoptimierende lanzettenvorrichtung mit adaptationsmittel für zeitliche schwankungen von hauteigenschaften |
| AU2002315180A1 (en) | 2001-06-12 | 2002-12-23 | Pelikan Technologies, Inc. | Electric lancet actuator |
| AU2002320094A1 (en) | 2001-06-12 | 2002-12-23 | Pelikan Technologies, Inc. | Integrated blood sampling analysis system with multi-use sampling module |
| US9427532B2 (en) | 2001-06-12 | 2016-08-30 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
| US9226699B2 (en) | 2002-04-19 | 2016-01-05 | Sanofi-Aventis Deutschland Gmbh | Body fluid sampling module with a continuous compression tissue interface surface |
| US8337419B2 (en) | 2002-04-19 | 2012-12-25 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
| EP1404235A4 (en) * | 2001-06-12 | 2008-08-20 | Pelikan Technologies Inc | METHOD AND DEVICE FOR A LANZETTING DEVICE INTEGRATED ON A BLOOD CARTRIDGE CARTRIDGE |
| US20070100255A1 (en) * | 2002-04-19 | 2007-05-03 | Pelikan Technologies, Inc. | Method and apparatus for body fluid sampling and analyte sensing |
| WO2002100252A2 (en) * | 2001-06-12 | 2002-12-19 | Pelikan Technologies, Inc. | Blood sampling apparatus and method |
| US9795747B2 (en) | 2010-06-02 | 2017-10-24 | Sanofi-Aventis Deutschland Gmbh | Methods and apparatus for lancet actuation |
| US7981056B2 (en) | 2002-04-19 | 2011-07-19 | Pelikan Technologies, Inc. | Methods and apparatus for lancet actuation |
| DE60239132D1 (de) * | 2001-06-12 | 2011-03-24 | Pelikan Technologies Inc | Gerät zur erhöhung der erfolgsrate im hinblick auf die durch einen fingerstich erhaltene blutausbeute |
| US7344894B2 (en) | 2001-10-16 | 2008-03-18 | Agilent Technologies, Inc. | Thermal regulation of fluidic samples within a diagnostic cartridge |
| US7331931B2 (en) | 2002-04-19 | 2008-02-19 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
| US7892183B2 (en) | 2002-04-19 | 2011-02-22 | Pelikan Technologies, Inc. | Method and apparatus for body fluid sampling and analyte sensing |
| US7717863B2 (en) | 2002-04-19 | 2010-05-18 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
| US7232451B2 (en) * | 2002-04-19 | 2007-06-19 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
| US7901362B2 (en) * | 2002-04-19 | 2011-03-08 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
| US7582099B2 (en) | 2002-04-19 | 2009-09-01 | Pelikan Technologies, Inc | Method and apparatus for penetrating tissue |
| US8221334B2 (en) | 2002-04-19 | 2012-07-17 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
| US7547287B2 (en) * | 2002-04-19 | 2009-06-16 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
| US9314194B2 (en) | 2002-04-19 | 2016-04-19 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
| US7485128B2 (en) * | 2002-04-19 | 2009-02-03 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
| US7674232B2 (en) * | 2002-04-19 | 2010-03-09 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
| US7198606B2 (en) | 2002-04-19 | 2007-04-03 | Pelikan Technologies, Inc. | Method and apparatus for a multi-use body fluid sampling device with analyte sensing |
| US8579831B2 (en) | 2002-04-19 | 2013-11-12 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
| US7371247B2 (en) * | 2002-04-19 | 2008-05-13 | Pelikan Technologies, Inc | Method and apparatus for penetrating tissue |
| US7175642B2 (en) | 2002-04-19 | 2007-02-13 | Pelikan Technologies, Inc. | Methods and apparatus for lancet actuation |
| US8267870B2 (en) | 2002-04-19 | 2012-09-18 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for body fluid sampling with hybrid actuation |
| US7410468B2 (en) * | 2002-04-19 | 2008-08-12 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
| US7648468B2 (en) | 2002-04-19 | 2010-01-19 | Pelikon Technologies, Inc. | Method and apparatus for penetrating tissue |
| US9248267B2 (en) | 2002-04-19 | 2016-02-02 | Sanofi-Aventis Deustchland Gmbh | Tissue penetration device |
| US7374544B2 (en) | 2002-04-19 | 2008-05-20 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
| US7481776B2 (en) * | 2002-04-19 | 2009-01-27 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
| US7909778B2 (en) * | 2002-04-19 | 2011-03-22 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
| US7229458B2 (en) | 2002-04-19 | 2007-06-12 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
| US7976476B2 (en) * | 2002-04-19 | 2011-07-12 | Pelikan Technologies, Inc. | Device and method for variable speed lancet |
| US9795334B2 (en) | 2002-04-19 | 2017-10-24 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
| US8784335B2 (en) | 2002-04-19 | 2014-07-22 | Sanofi-Aventis Deutschland Gmbh | Body fluid sampling device with a capacitive sensor |
| US7491178B2 (en) * | 2002-04-19 | 2009-02-17 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
| US7291117B2 (en) | 2002-04-19 | 2007-11-06 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
| US7563232B2 (en) * | 2002-04-19 | 2009-07-21 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
| US7297122B2 (en) | 2002-04-19 | 2007-11-20 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
| US7141058B2 (en) * | 2002-04-19 | 2006-11-28 | Pelikan Technologies, Inc. | Method and apparatus for a body fluid sampling device using illumination |
| US7524293B2 (en) * | 2002-04-19 | 2009-04-28 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
| US8702624B2 (en) | 2006-09-29 | 2014-04-22 | Sanofi-Aventis Deutschland Gmbh | Analyte measurement device with a single shot actuator |
| US7727181B2 (en) * | 2002-10-09 | 2010-06-01 | Abbott Diabetes Care Inc. | Fluid delivery device with autocalibration |
| US7993108B2 (en) * | 2002-10-09 | 2011-08-09 | Abbott Diabetes Care Inc. | Variable volume, shape memory actuated insulin dispensing pump |
| AU2003279237A1 (en) * | 2002-10-09 | 2004-05-04 | Therasense, Inc. | Fluid delivery device, system and method |
| US8574895B2 (en) | 2002-12-30 | 2013-11-05 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus using optical techniques to measure analyte levels |
| US7811231B2 (en) | 2002-12-31 | 2010-10-12 | Abbott Diabetes Care Inc. | Continuous glucose monitoring system and methods of use |
| WO2004060174A2 (en) * | 2002-12-31 | 2004-07-22 | Pelikan Technologies Inc. | Method and apparatus for loading penetrating members |
| US7679407B2 (en) * | 2003-04-28 | 2010-03-16 | Abbott Diabetes Care Inc. | Method and apparatus for providing peak detection circuitry for data communication systems |
| WO2004107964A2 (en) | 2003-06-06 | 2004-12-16 | Pelikan Technologies, Inc. | Blood harvesting device with electronic control |
| US8066639B2 (en) | 2003-06-10 | 2011-11-29 | Abbott Diabetes Care Inc. | Glucose measuring device for use in personal area network |
| WO2005006939A2 (en) * | 2003-06-11 | 2005-01-27 | Pelikan Technologies, Inc. | Method and apparatus for body fluid sampling and analyte sensing |
| WO2006001797A1 (en) | 2004-06-14 | 2006-01-05 | Pelikan Technologies, Inc. | Low pain penetrating |
| US7604592B2 (en) | 2003-06-13 | 2009-10-20 | Pelikan Technologies, Inc. | Method and apparatus for a point of care device |
| US8282576B2 (en) * | 2003-09-29 | 2012-10-09 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for an improved sample capture device |
| EP1680014A4 (en) * | 2003-10-14 | 2009-01-21 | Pelikan Technologies Inc | METHOD AND DEVICE FOR A VARIABLE USER INTERFACE |
| EP3175780A1 (en) | 2003-12-18 | 2017-06-07 | Metronom Health, Inc. | Implantable biosensor and methods of use thereof |
| US7822454B1 (en) | 2005-01-03 | 2010-10-26 | Pelikan Technologies, Inc. | Fluid sampling device with improved analyte detecting member configuration |
| EP1706026B1 (en) | 2003-12-31 | 2017-03-01 | Sanofi-Aventis Deutschland GmbH | Method and apparatus for improving fluidic flow and sample capture |
| WO2005089103A2 (en) | 2004-02-17 | 2005-09-29 | Therasense, Inc. | Method and system for providing data communication in continuous glucose monitoring and management system |
| WO2006011062A2 (en) | 2004-05-20 | 2006-02-02 | Albatros Technologies Gmbh & Co. Kg | Printable hydrogel for biosensors |
| WO2005120365A1 (en) | 2004-06-03 | 2005-12-22 | Pelikan Technologies, Inc. | Method and apparatus for a fluid sampling device |
| US20070027383A1 (en) * | 2004-07-01 | 2007-02-01 | Peyser Thomas A | Patches, systems, and methods for non-invasive glucose measurement |
| AU2005262444A1 (en) | 2004-07-01 | 2006-01-19 | Vivomedical, Inc. | Non-invasive glucose measurement |
| US8652831B2 (en) | 2004-12-30 | 2014-02-18 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for analyte measurement test time |
| US20060166629A1 (en) * | 2005-01-24 | 2006-07-27 | Therasense, Inc. | Method and apparatus for providing EMC Class-B compliant RF transmitter for data monitoring an detection systems |
| JP2008535548A (ja) | 2005-03-21 | 2008-09-04 | アボット ダイアビーティーズ ケア インコーポレイテッド | 統合医薬注入／検体モニタリングシステムを提供するための方法及びシステム |
| US8388523B2 (en) * | 2005-04-01 | 2013-03-05 | Welch Allyn, Inc. | Medical diagnostic instrument having portable illuminator |
| CA2603285C (en) * | 2005-04-01 | 2015-09-01 | Welch Allyn, Inc. | Vaginal speculum |
| US8112240B2 (en) * | 2005-04-29 | 2012-02-07 | Abbott Diabetes Care Inc. | Method and apparatus for providing leak detection in data monitoring and management systems |
| US7768408B2 (en) | 2005-05-17 | 2010-08-03 | Abbott Diabetes Care Inc. | Method and system for providing data management in data monitoring system |
| US7620437B2 (en) * | 2005-06-03 | 2009-11-17 | Abbott Diabetes Care Inc. | Method and apparatus for providing rechargeable power in data monitoring and management systems |
| US20060281187A1 (en) | 2005-06-13 | 2006-12-14 | Rosedale Medical, Inc. | Analyte detection devices and methods with hematocrit/volume correction and feedback control |
| US7756561B2 (en) | 2005-09-30 | 2010-07-13 | Abbott Diabetes Care Inc. | Method and apparatus for providing rechargeable power in data monitoring and management systems |
| US8801631B2 (en) | 2005-09-30 | 2014-08-12 | Intuity Medical, Inc. | Devices and methods for facilitating fluid transport |
| EP1928316B1 (en) | 2005-09-30 | 2014-02-26 | Intuity Medical, Inc. | Multi-site body fluid sampling and analysis cartridge |
| US20090196580A1 (en) * | 2005-10-06 | 2009-08-06 | Freeman Dominique M | Method and apparatus for an analyte detecting device |
| US7583190B2 (en) | 2005-10-31 | 2009-09-01 | Abbott Diabetes Care Inc. | Method and apparatus for providing data communication in data monitoring and management systems |
| US7766829B2 (en) | 2005-11-04 | 2010-08-03 | Abbott Diabetes Care Inc. | Method and system for providing basal profile modification in analyte monitoring and management systems |
| US8344966B2 (en) | 2006-01-31 | 2013-01-01 | Abbott Diabetes Care Inc. | Method and system for providing a fault tolerant display unit in an electronic device |
| US7620438B2 (en) | 2006-03-31 | 2009-11-17 | Abbott Diabetes Care Inc. | Method and system for powering an electronic device |
| US8226891B2 (en) | 2006-03-31 | 2012-07-24 | Abbott Diabetes Care Inc. | Analyte monitoring devices and methods therefor |
| US8142352B2 (en) * | 2006-04-03 | 2012-03-27 | Welch Allyn, Inc. | Vaginal speculum assembly having portable illuminator |
| US8679630B2 (en) * | 2006-05-17 | 2014-03-25 | Purdue Research Foundation | Vertical carbon nanotube device in nanoporous templates |
| US20090054749A1 (en) * | 2006-05-31 | 2009-02-26 | Abbott Diabetes Care, Inc. | Method and System for Providing Data Transmission in a Data Management System |
| US7920907B2 (en) | 2006-06-07 | 2011-04-05 | Abbott Diabetes Care Inc. | Analyte monitoring system and method |
| US20080119710A1 (en) * | 2006-10-31 | 2008-05-22 | Abbott Diabetes Care, Inc. | Medical devices and methods of using the same |
| US8579853B2 (en) | 2006-10-31 | 2013-11-12 | Abbott Diabetes Care Inc. | Infusion devices and methods |
| US20080214919A1 (en) * | 2006-12-26 | 2008-09-04 | Lifescan, Inc. | System and method for implementation of glycemic control protocols |
| US9487877B2 (en) * | 2007-02-01 | 2016-11-08 | Purdue Research Foundation | Contact metallization of carbon nanotubes |
| US8732188B2 (en) | 2007-02-18 | 2014-05-20 | Abbott Diabetes Care Inc. | Method and system for providing contextual based medication dosage determination |
| US8930203B2 (en) | 2007-02-18 | 2015-01-06 | Abbott Diabetes Care Inc. | Multi-function analyte test device and methods therefor |
| US8123686B2 (en) | 2007-03-01 | 2012-02-28 | Abbott Diabetes Care Inc. | Method and apparatus for providing rolling data in communication systems |
| RU2444980C2 (ru) | 2007-03-07 | 2012-03-20 | Эко Терапьютикс, Инк. | Трансдермальная система мониторинга аналита и способы детекции аналита |
| EP2170160A4 (en) * | 2007-05-07 | 2013-01-23 | Cybiocare Inc | NON-INVASIVE PRESSURE DIRECTION |
| US8461985B2 (en) | 2007-05-08 | 2013-06-11 | Abbott Diabetes Care Inc. | Analyte monitoring system and methods |
| US8456301B2 (en) | 2007-05-08 | 2013-06-04 | Abbott Diabetes Care Inc. | Analyte monitoring system and methods |
| US7928850B2 (en) | 2007-05-08 | 2011-04-19 | Abbott Diabetes Care Inc. | Analyte monitoring system and methods |
| US8665091B2 (en) | 2007-05-08 | 2014-03-04 | Abbott Diabetes Care Inc. | Method and device for determining elapsed sensor life |
| US20080306362A1 (en) * | 2007-06-05 | 2008-12-11 | Owen Davis | Device and system for monitoring contents of perspiration |
| US8083677B2 (en) * | 2007-09-24 | 2011-12-27 | Baxter International Inc. | Access disconnect detection using glucose |
| JP5186887B2 (ja) * | 2007-11-09 | 2013-04-24 | オムロンヘルスケア株式会社 | 血中成分濃度測定装置および血中成分濃度測定方法 |
| WO2009126900A1 (en) | 2008-04-11 | 2009-10-15 | Pelikan Technologies, Inc. | Method and apparatus for analyte detecting device |
| WO2009145920A1 (en) | 2008-05-30 | 2009-12-03 | Intuity Medical, Inc. | Body fluid sampling device -- sampling site interface |
| US20100069726A1 (en) * | 2008-06-04 | 2010-03-18 | Seventh Sense Biosystems, Inc. | Compositions and methods for rapid one-step diagnosis |
| JP5642066B2 (ja) | 2008-06-06 | 2014-12-17 | インテュイティ メディカル インコーポレイテッド | 体液の試料内に含まれている検体の存在または濃度を決定する検定を行う方法および装置 |
| EP2299904B1 (en) | 2008-06-06 | 2019-09-11 | Intuity Medical, Inc. | Medical measurement method |
| WO2010013808A1 (ja) * | 2008-07-31 | 2010-02-04 | シスメックス株式会社 | 生体内成分測定方法、生体内成分測定のためのデータ処理方法、生体内成分測定装置および収集部材 |
| WO2010030609A1 (en) * | 2008-09-09 | 2010-03-18 | Vivomedical, Inc. | Sweat collection devices for glucose measurement |
| WO2010045247A1 (en) * | 2008-10-14 | 2010-04-22 | Vivomedical, Inc. | Sweat glucose sensors and collection devices for glucose measurement |
| CA2740421C (en) * | 2008-10-15 | 2018-08-28 | The University Of Memphis Research Foundation | Method and device for detection of bioavailable drug concentration in a fluid sample |
| US11375929B2 (en) | 2008-10-15 | 2022-07-05 | The University Of Tennessee Research Foundation | Method and device for detection of bioavailable drug concentration in a fluid sample |
| JP2010167130A (ja) * | 2009-01-23 | 2010-08-05 | Omron Healthcare Co Ltd | 体液収集装置および体液分析装置 |
| US8715981B2 (en) * | 2009-01-27 | 2014-05-06 | Purdue Research Foundation | Electrochemical biosensor |
| US8103456B2 (en) | 2009-01-29 | 2012-01-24 | Abbott Diabetes Care Inc. | Method and device for early signal attenuation detection using blood glucose measurements |
| JP5218106B2 (ja) * | 2009-01-30 | 2013-06-26 | オムロンヘルスケア株式会社 | 血中成分濃度変化測定装置 |
| US20100198196A1 (en) * | 2009-01-30 | 2010-08-05 | Abbott Diabetes Care, Inc. | Therapy Delivery Device Programming Tool |
| US8560082B2 (en) | 2009-01-30 | 2013-10-15 | Abbott Diabetes Care Inc. | Computerized determination of insulin pump therapy parameters using real time and retrospective data processing |
| US9375169B2 (en) | 2009-01-30 | 2016-06-28 | Sanofi-Aventis Deutschland Gmbh | Cam drive for managing disposable penetrating member actions with a single motor and motor and control system |
| WO2012018486A2 (en) | 2010-07-26 | 2012-02-09 | Seventh Sense Biosystems, Inc. | Rapid delivery and/or receiving of fluids |
| CN102405018B (zh) | 2009-03-02 | 2014-11-19 | 第七感生物系统有限公司 | 与血液取样相关联的技术和装置 |
| US20110105872A1 (en) * | 2009-10-30 | 2011-05-05 | Seventh Sense Biosystems, Inc. | Systems and methods for application to skin and control of actuation, delivery, and/or perception thereof |
| US9041541B2 (en) * | 2010-01-28 | 2015-05-26 | Seventh Sense Biosystems, Inc. | Monitoring or feedback systems and methods |
| US9295417B2 (en) | 2011-04-29 | 2016-03-29 | Seventh Sense Biosystems, Inc. | Systems and methods for collecting fluid from a subject |
| US8872154B2 (en) * | 2009-04-06 | 2014-10-28 | Purdue Research Foundation | Field effect transistor fabrication from carbon nanotubes |
| US9226701B2 (en) | 2009-04-28 | 2016-01-05 | Abbott Diabetes Care Inc. | Error detection in critical repeating data in a wireless sensor system |
| US8467972B2 (en) * | 2009-04-28 | 2013-06-18 | Abbott Diabetes Care Inc. | Closed loop blood glucose control algorithm analysis |
| WO2010138856A1 (en) | 2009-05-29 | 2010-12-02 | Abbott Diabetes Care Inc. | Medical device antenna systems having external antenna configurations |
| DK3936032T3 (da) | 2009-07-23 | 2024-07-29 | Abbott Diabetes Care Inc | Realtidshåndtering af data relateret til fysiologisk styring af glukoseniveauer |
| JP5572016B2 (ja) * | 2009-08-04 | 2014-08-13 | シスメックス株式会社 | 組織液抽出用デバイス、その製造方法、及び該デバイスを用いた組織液の分析方法 |
| US8993331B2 (en) | 2009-08-31 | 2015-03-31 | Abbott Diabetes Care Inc. | Analyte monitoring system and methods for managing power and noise |
| EP2473098A4 (en) | 2009-08-31 | 2014-04-09 | Abbott Diabetes Care Inc | ANALYTICAL SIGNAL PROCESSING APPARATUS AND METHOD |
| US9320461B2 (en) * | 2009-09-29 | 2016-04-26 | Abbott Diabetes Care Inc. | Method and apparatus for providing notification function in analyte monitoring systems |
| JP2011232320A (ja) * | 2009-10-01 | 2011-11-17 | Sony Corp | 生体内物質検出用プローブ、および該生体内物質検出用プローブを用いた生体内物質検出装置 |
| WO2011065972A2 (en) * | 2009-11-24 | 2011-06-03 | Seventh Sense Biosystems, Inc. | Patient-enacted sampling technique |
| EP2506768B1 (en) | 2009-11-30 | 2016-07-06 | Intuity Medical, Inc. | Calibration material delivery devices and methods |
| WO2011081596A1 (en) * | 2009-12-30 | 2011-07-07 | Cma Microdialysis Ab | Sensor arrangement for continuously measuring analytes in a biological fluid |
| CN102119860B (zh) * | 2010-01-12 | 2013-07-17 | 长庚医学科技股份有限公司 | 非侵入式血糖量测系统和测量方法 |
| JP5826766B2 (ja) * | 2010-01-13 | 2015-12-02 | セブンス センス バイオシステムズ，インコーポレーテッド | 試料採取デバイスインタフェース |
| CN102811754B (zh) * | 2010-01-13 | 2017-05-17 | 第七感生物系统有限公司 | 流体的快速输送和/或抽出 |
| JP5735773B2 (ja) * | 2010-03-29 | 2015-06-17 | シスメックス株式会社 | 生体成分分析方法及び生体成分分析装置 |
| US8965476B2 (en) | 2010-04-16 | 2015-02-24 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
| CN103108587B (zh) * | 2010-05-17 | 2016-09-21 | 申提留斯控股有限公司 | 检测装置和相关使用方法 |
| GB201008448D0 (en) * | 2010-05-20 | 2010-07-07 | Univ Strathclyde | Transdermal device |
| WO2011163347A2 (en) | 2010-06-23 | 2011-12-29 | Seventh Sense Biosystems, Inc. | Sampling devices and methods involving relatively little pain |
| WO2012009613A1 (en) | 2010-07-16 | 2012-01-19 | Seventh Sense Biosystems, Inc. | Low-pressure environment for fluid transfer devices |
| WO2012021801A2 (en) | 2010-08-13 | 2012-02-16 | Seventh Sense Biosystems, Inc. | Systems and techniques for monitoring subjects |
| EP2992827B1 (en) | 2010-11-09 | 2017-04-19 | Seventh Sense Biosystems, Inc. | Systems and interfaces for blood sampling |
| JP5801590B2 (ja) * | 2011-04-11 | 2015-10-28 | シスメックス株式会社 | 生体成分測定方法 |
| US20130158468A1 (en) | 2011-12-19 | 2013-06-20 | Seventh Sense Biosystems, Inc. | Delivering and/or receiving material with respect to a subject surface |
| CN103874460B (zh) | 2011-04-29 | 2016-06-22 | 第七感生物系统有限公司 | 一种用于从受验者的皮肤接收血液或其它物质的装置 |
| KR20140034200A (ko) | 2011-04-29 | 2014-03-19 | 세븐쓰 센스 바이오시스템즈, 인크. | 혈액 스폿들 또는 다른 신체 유체들을 수집 및/또는 조작하기 위한 시스템들 및 방법들 |
| CA2843945C (en) | 2011-08-03 | 2022-06-21 | Intuity Medical, Inc. | Devices and methods for body fluid sampling and analysis |
| US20130060106A1 (en) | 2011-09-06 | 2013-03-07 | Medtronic Minimed, Inc. | Optical sensing systems and methods |
| WO2013064313A1 (en) | 2011-10-31 | 2013-05-10 | Sentec Ag | A device for application of a sensor to a measurement site, a sensor head, a kit of an application device and sensor and use of an application device for optical measurements of physiological parameters |
| EP3677182B1 (en) | 2011-11-07 | 2022-05-04 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods |
| RU2653633C2 (ru) * | 2012-03-01 | 2018-05-11 | Конинклейке Филипс Н.В. | Датчик определения концентрации газа |
| EP2834007B1 (en) | 2012-04-04 | 2019-06-26 | University of Cincinnati | Device and method for sweat collection |
| US9968306B2 (en) | 2012-09-17 | 2018-05-15 | Abbott Diabetes Care Inc. | Methods and apparatuses for providing adverse condition notification with enhanced wireless communication range in analyte monitoring systems |
| DK2941195T3 (en) | 2013-01-02 | 2017-03-06 | Fibrotx Oü | Device for measuring analytes in the skin |
| CN105408493A (zh) * | 2013-07-31 | 2016-03-16 | 圣铁克私人有限公司 | 用于测量生物流体中的分析物的系统、装置、媒介及方法 |
| WO2015051288A1 (en) * | 2013-10-03 | 2015-04-09 | Leszinske Alan J | Apparatus and method for automated blood analyte monitoring |
| WO2015057743A1 (en) * | 2013-10-14 | 2015-04-23 | Theranos, Inc. | Methods and systems for obtaining clinical samples |
| CA2927213A1 (en) | 2013-10-18 | 2015-04-23 | University Of Cincinnati | Sweat sensing with chronological assurance |
| US10888244B2 (en) | 2013-10-18 | 2021-01-12 | University Of Cincinnati | Sweat sensing with chronological assurance |
| EP3165154A3 (en) | 2013-10-18 | 2017-07-26 | University of Cincinnati | Devices for integrated, repeated, prolonged, and/or reliable sweat stimulation and biosensing |
| US9459089B2 (en) * | 2014-04-09 | 2016-10-04 | Qualcomm Incorporated | Method, devices and systems for detecting an attachment of an electronic patch |
| WO2015184097A2 (en) | 2014-05-28 | 2015-12-03 | University Of Cincinnati | Devices with reduced sweat volumes between sensors and sweat glands |
| EP3148420A4 (en) | 2014-05-28 | 2018-09-19 | University of Cincinnati | Sweat monitoring and control of drug delivery |
| US10932761B2 (en) | 2014-05-28 | 2021-03-02 | University Of Cincinnati | Advanced sweat sensor adhesion, sealing, and fluidic strategies |
| EP2974656A1 (en) * | 2014-07-14 | 2016-01-20 | Universität Zürich | Device for measuring the concentration of an analyte in the blood or tissue of an animal or a human, particularly a premature infant, in a self-calibrating manner |
| US9532706B2 (en) | 2014-08-07 | 2017-01-03 | Welch Allyn, Inc. | Vaginal speculum with illuminator |
| EP3197343A4 (en) * | 2014-09-22 | 2018-04-18 | University of Cincinnati | Sweat sensing with analytical assurance |
| CN104280444B (zh) * | 2014-10-15 | 2019-12-17 | 南京皓运投资管理有限公司 | 汗液收集及分析系统及其制作方法 |
| KR102335739B1 (ko) * | 2014-12-19 | 2021-12-06 | 삼성전자주식회사 | 비 침습적 혈당 측정 방법 및 이를 위한 장치 |
| KR20160089718A (ko) | 2015-01-20 | 2016-07-28 | 삼성전자주식회사 | 센서 모듈 및 그를 구비하는 착용형 체성분 분석 장치 |
| WO2016117520A1 (ja) * | 2015-01-21 | 2016-07-28 | 国立研究開発法人日本原子力研究開発機構 | 血中物質濃度測定装置及び血中物質濃度測定方法 |
| CN104545817B (zh) * | 2015-01-29 | 2017-09-29 | 长沙一卫医疗科技有限公司 | 一种非介入检测汗腺汗液离子状况的传感器 |
| US10485460B2 (en) | 2015-02-13 | 2019-11-26 | University Of Cincinnati | Devices for integrated indirect sweat stimulation and sensing |
| US20180042585A1 (en) * | 2015-02-20 | 2018-02-15 | University Of Cincinnati | Sweat sensing devices with prioritized sweat data from a subset of sensors |
| KR101789703B1 (ko) * | 2015-06-12 | 2017-10-25 | 서울대학교산학협력단 | 바이오 센서 및 그 형성 방법 |
| GB201510909D0 (en) * | 2015-06-22 | 2015-08-05 | Surescreen Diagnostics Ltd | Detection apparatus |
| US20180292325A1 (en) * | 2015-06-23 | 2018-10-11 | Case Western Reserve University | Systems and methods for optochemical imaging of a chemically active surface |
| US10695000B2 (en) | 2015-09-02 | 2020-06-30 | Metronom Health, Inc. | Systems and methods for continuous health monitoring using an opto-enzymatic analyte sensor |
| US20170065231A1 (en) * | 2015-09-04 | 2017-03-09 | Goldensunda Technology Co., Ltd. | Noninvasive blood sugar measurement device |
| ITUB20154036A1 (it) * | 2015-09-30 | 2017-03-30 | St Microelectronics Srl | Biosensore per il rilevamento di analiti nel sudore, e metodo di fabbricazione del biosensore |
| CN108430308A (zh) | 2015-10-30 | 2018-08-21 | 辛辛那提大学 | 具有电磁屏蔽传感器、互连和电子器件的汗液感测设备 |
| WO2017087912A2 (en) * | 2015-11-20 | 2017-05-26 | Duke University | Ratiometric biosensors and non-geometrically modulated fret |
| GB2535614B (en) | 2015-12-22 | 2017-06-14 | Tfm Invent Ltd | A skin patch |
| US10993657B1 (en) * | 2015-12-30 | 2021-05-04 | Halo Wearables, Llc | Wearable hydration monitor sensors |
| CN106983516A (zh) * | 2016-01-20 | 2017-07-28 | 金上达科技股份有限公司 | 非侵入式血糖检测装置 |
| US10746663B2 (en) * | 2016-02-26 | 2020-08-18 | DermaTec LLC | Methods and apparatuses relating to dermal biochemical sensors |
| PT3216395T (pt) * | 2016-03-11 | 2021-10-15 | Hoffmann La Roche | Adesivo de medição de analito |
| US10471249B2 (en) | 2016-06-08 | 2019-11-12 | University Of Cincinnati | Enhanced analyte access through epithelial tissue |
| US11253190B2 (en) | 2016-07-01 | 2022-02-22 | University Of Cincinnati | Devices with reduced microfluidic volume between sensors and sweat glands |
| WO2018035443A1 (en) | 2016-08-19 | 2018-02-22 | University Of Cincinnati | Prolonged sweat stimulation |
| WO2018039652A1 (en) * | 2016-08-26 | 2018-03-01 | Cardiac Pacemakers, Inc. | Systems and methods for determining an abnormal glycemic event using surrogates for glucose |
| AU2017340405B2 (en) * | 2016-10-04 | 2023-06-29 | Ch2M Hill, Inc. | Passive device for vapor intrusion sampling |
| GB2559627A (en) * | 2017-02-14 | 2018-08-15 | Ndm Tech Ltd | Device |
| US10506926B2 (en) | 2017-02-18 | 2019-12-17 | Arc Devices Limited | Multi-vital sign detector in an electronic medical records system |
| US10492684B2 (en) | 2017-02-21 | 2019-12-03 | Arc Devices Limited | Multi-vital-sign smartphone system in an electronic medical records system |
| WO2018165180A1 (en) | 2017-03-06 | 2018-09-13 | Medtronic Minimed, Inc. | Colorometric sensor for the non-invasive screening of glucose in sweat in pre and type 2 diabetes |
| US20180249935A1 (en) * | 2017-03-06 | 2018-09-06 | Medtronic Minimed, Inc. | Colorometric sensor for the non-invasive screening of glucose in sweat in pre and type 2 diabetes |
| KR101947586B1 (ko) * | 2017-05-31 | 2019-04-29 | 광운대학교 산학협력단 | 혈당 측정기 및 이를 이용한 혈당 측정 시스템 |
| US10602987B2 (en) | 2017-08-10 | 2020-03-31 | Arc Devices Limited | Multi-vital-sign smartphone system in an electronic medical records system |
| WO2019051107A1 (en) * | 2017-09-07 | 2019-03-14 | The Regents Of The University Of California | PORTABLE MULTI-PUSH SENSOR EXTRACTION AND DETECTION DEVICE FOR STANDARDIZED AND SEQUENTIAL SWEAT ANALYSIS IN TIME |
| US11857313B2 (en) | 2017-09-11 | 2024-01-02 | University Of Cincinnati | Sweat biosensing companion devices and subsystems |
| US11490862B2 (en) * | 2017-11-13 | 2022-11-08 | Senseonics, Incorporated | Analyte monitoring system and method for determining system usage |
| US20210076991A1 (en) * | 2018-01-16 | 2021-03-18 | The Regents Of The University Of California | In-situ sweat rate monitoring for normalization of sweat analyte concentrations |
| CN108451550B (zh) * | 2018-01-29 | 2021-03-19 | 肖向梅 | 一种化验科医用手部体液采验器 |
| CN108742647A (zh) * | 2018-04-30 | 2018-11-06 | 中山市京春电子科技有限公司 | 一种便携式血糖检测设备 |
| US10485431B1 (en) | 2018-05-21 | 2019-11-26 | ARC Devices Ltd. | Glucose multi-vital-sign system in an electronic medical records system |
| US20210338117A1 (en) * | 2018-09-05 | 2021-11-04 | Kwangwoon University Industry-Academic Collaboration Foundation | Blood glucose measurement device and blood glucose measurement system using same |
| KR102655742B1 (ko) * | 2018-09-11 | 2024-04-05 | 삼성전자주식회사 | 분석 물질의 혈중 농도 측정 장치 및 방법 |
| CN113194814A (zh) * | 2018-11-13 | 2021-07-30 | 辛辛那提大学 | 所采集的间质液样本的质量保证 |
| CN109646018A (zh) * | 2019-01-17 | 2019-04-19 | 浙江大学 | 一种用于汗液葡萄糖检测的无线无源柔性传感装置及方法 |
| EP3756544A1 (en) * | 2019-06-26 | 2020-12-30 | Koninklijke Philips N.V. | System and method for correcting a sweat analyte measurement |
| US20210106260A1 (en) * | 2019-10-11 | 2021-04-15 | The Regents Of The University Of California | Mediator-free biochemical sensing device and method for noninvasively and electrochemically sensing in vivo biochemicals |
| WO2021247300A1 (en) | 2020-06-01 | 2021-12-09 | Arc Devices Limited | Apparatus and methods for measuring blood pressure and other vital signs via a finger |
| KR102334848B1 (ko) * | 2020-06-12 | 2021-12-06 | 국민대학교산학협력단 | 바이오 센싱 모듈, 이의 동작 방법, 및 이를 이용하는 바이오 센싱 시스템 |
| US20220061705A1 (en) * | 2020-08-05 | 2022-03-03 | The Regents Of The University Of California | Programmable epidermal microfluidic valving system for wearable biofluid management and contextual biomarker analysis |
| CN111982869B (zh) * | 2020-08-06 | 2023-09-19 | 中国科学院合肥物质科学研究院 | 一种用于定量荧光测量的校准方法及校准配件 |
| KR102758471B1 (ko) * | 2021-11-30 | 2025-01-22 | 계명대학교 산학협력단 | 글루코스 및 락테이트 동시측정 바이오 센서 |
| CN114652306A (zh) * | 2022-03-17 | 2022-06-24 | 电子科技大学 | 基于MOFs的指尖接触式无创汗液葡萄糖传感器及方法 |
| JP2025521184A (ja) | 2022-06-03 | 2025-07-08 | アーク デヴァイシズ リミテッド | 手指を介して血圧及び他のバイタルサインを測定する装置及び方法 |
| CN115655957A (zh) * | 2022-09-27 | 2023-01-31 | 安阳工学院 | 一种以汗液测血糖的血糖仪 |
| CN116195997A (zh) * | 2022-11-22 | 2023-06-02 | 厦门大学深圳研究院 | 汗液葡萄糖浓度检测系统 |
| CN116297734A (zh) * | 2023-02-22 | 2023-06-23 | 桂林电子科技大学 | 一种基于多步电压阶跃法的汗液葡萄糖检测装置及方法 |
| CN119174607A (zh) * | 2024-08-19 | 2024-12-24 | 宁波大学 | 一种用于汗液中葡萄糖检测的可穿戴贴片及其制备方法与应用 |
Family Cites Families (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3551554A (en) | 1968-08-16 | 1970-12-29 | Crown Zellerbach Corp | Enhancing tissue penetration of physiologically active agents with dmso |
| US4444193A (en) * | 1982-01-11 | 1984-04-24 | Medtronic, Inc. | Fluid absorbent quantitative test device |
| JPH06119B2 (ja) * | 1985-09-26 | 1994-01-05 | 株式会社日立製作所 | 汗中有機物及び電解質検出用経皮センサ |
| JPH06121B2 (ja) * | 1986-07-26 | 1994-01-05 | 株式会社日立製作所 | 無侵襲生化学物質計測装置 |
| US4821733A (en) * | 1987-08-18 | 1989-04-18 | Dermal Systems International | Transdermal detection system |
| US5441048A (en) | 1988-09-08 | 1995-08-15 | Sudor Partners | Method and apparatus for determination of chemical species in perspiration |
| US5465713A (en) * | 1988-09-08 | 1995-11-14 | Sudor Partners | Energy-assisted transdermal collection patch for accelerated analyte collection and method of use |
| US5140985A (en) * | 1989-12-11 | 1992-08-25 | Schroeder Jon M | Noninvasive blood glucose measuring device |
| US5036861A (en) | 1990-01-11 | 1991-08-06 | Sembrowich Walter L | Method and apparatus for non-invasively monitoring plasma glucose levels |
| US5306861A (en) | 1990-10-31 | 1994-04-26 | Amos Philip I | Temporary wall covering |
| US20020169394A1 (en) * | 1993-11-15 | 2002-11-14 | Eppstein Jonathan A. | Integrated tissue poration, fluid harvesting and analysis device, and method therefor |
| US5443080A (en) * | 1993-12-22 | 1995-08-22 | Americate Transtech, Inc. | Integrated system for biological fluid constituent analysis |
| CZ288371B6 (en) | 1994-06-30 | 2001-06-13 | Procter & Gamble | Structure for transport of liquids and process for producing thereof |
| GB9415499D0 (en) * | 1994-08-01 | 1994-09-21 | Bartlett Philip N | Electrodes and their use in analysis |
| SE510733C2 (sv) | 1995-01-03 | 1999-06-21 | Chemel Ab | Kemisk sensor baserad på utbytbar igenkänningskomponent samt användning därav |
| EP0836407A4 (en) * | 1995-06-07 | 1999-09-22 | Sudor Partners | TRANSDERMAL STAMP WITHOUT SEPARATE ABSORBENT MATERIAL |
| US5954685A (en) * | 1996-05-24 | 1999-09-21 | Cygnus, Inc. | Electrochemical sensor with dual purpose electrode |
| WO1998022820A1 (en) | 1996-11-21 | 1998-05-28 | Lawrence Livermore National Laboratory | Detection of biological molecules using boronate-based chemical amplification and optical sensors |
| US6420622B1 (en) * | 1997-08-01 | 2002-07-16 | 3M Innovative Properties Company | Medical article having fluid control film |
| US6503198B1 (en) | 1997-09-11 | 2003-01-07 | Jack L. Aronowtiz | Noninvasive transdermal systems for detecting an analyte obtained from or underneath skin and methods |
| US6117290A (en) | 1997-09-26 | 2000-09-12 | Pepex Biomedical, Llc | System and method for measuring a bioanalyte such as lactate |
| US6479015B1 (en) | 1998-03-03 | 2002-11-12 | Pepex Biomedical, Llc | Apparatus for monitoring a level of a chemical species in a body fluid |
| US9066695B2 (en) | 1998-04-30 | 2015-06-30 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US6175752B1 (en) * | 1998-04-30 | 2001-01-16 | Therasense, Inc. | Analyte monitoring device and methods of use |
| PT1077636E (pt) * | 1998-05-13 | 2004-06-30 | Cygnus Therapeutic Systems | Processamento de sinal para medicao de analitos fisiologicos |
| JP3507437B2 (ja) * | 1998-05-13 | 2004-03-15 | シグナス， インコーポレイテッド | 経皮サンプリング系のための収集アセンブリ |
| US6128519A (en) | 1998-12-16 | 2000-10-03 | Pepex Biomedical, Llc | System and method for measuring a bioanalyte such as lactate |
| US20040171980A1 (en) | 1998-12-18 | 2004-09-02 | Sontra Medical, Inc. | Method and apparatus for enhancement of transdermal transport |
| DE60028991T2 (de) | 1999-10-07 | 2007-02-08 | Pepex Biomedical, LLC, Alameda | Sensor, bestehend aus einer isolierenden Ummantelung, enthaltend darin eine Vielzahl von leitfähigen Fasern, die zumindestens teilweise von einem sensitiven Material umgeben sind und Hohlräume zwischen den Fasern enthalten |
| US6464849B1 (en) | 1999-10-07 | 2002-10-15 | Pepex Biomedical, L.L.C. | Sensor for measuring a bioanalyte such as lactate |
| US7323143B2 (en) | 2000-05-25 | 2008-01-29 | President And Fellows Of Harvard College | Microfluidic systems including three-dimensionally arrayed channel networks |
| CA2409826C (en) | 2000-06-01 | 2010-02-02 | Science Applications International Corporation | Systems and methods for monitoring health and delivering drugs transdermally |
| US6905816B2 (en) | 2000-11-27 | 2005-06-14 | Intelligent Medical Devices, Inc. | Clinically intelligent diagnostic devices and methods |
| GB0030929D0 (en) * | 2000-12-19 | 2001-01-31 | Inverness Medical Ltd | Analyte measurement |
| US20050009101A1 (en) | 2001-05-17 | 2005-01-13 | Motorola, Inc. | Microfluidic devices comprising biochannels |
| GB0120202D0 (en) * | 2001-08-18 | 2001-10-10 | Psimedica | Body fluid collection and analysis |
| CA2464738A1 (en) * | 2001-11-09 | 2003-05-15 | Dow Global Technologies Inc. | Hand-held medical apparatus |
| US7892183B2 (en) * | 2002-04-19 | 2011-02-22 | Pelikan Technologies, Inc. | Method and apparatus for body fluid sampling and analyte sensing |
| US7198606B2 (en) * | 2002-04-19 | 2007-04-03 | Pelikan Technologies, Inc. | Method and apparatus for a multi-use body fluid sampling device with analyte sensing |
| KR101124876B1 (ko) * | 2002-04-22 | 2012-03-28 | 마시오 마크 아우렐리오 마틴스 애브리우 | 생물학적 파라미터 측정 장치 및 방법 |
| US8849379B2 (en) * | 2002-04-22 | 2014-09-30 | Geelux Holdings, Ltd. | Apparatus and method for measuring biologic parameters |
| US20030215487A1 (en) * | 2002-05-17 | 2003-11-20 | Il Yang Pharm Co., Ltd. Republic Of Korea | Matrix-type device for the transdermal delivery of testosterone applied to the non-scrotal skin |
| US6998598B2 (en) * | 2002-08-02 | 2006-02-14 | Sandia National Labroatories | Modular optical detector system |
| US7381184B2 (en) | 2002-11-05 | 2008-06-03 | Abbott Diabetes Care Inc. | Sensor inserter assembly |
| US20040214492A1 (en) | 2003-04-22 | 2004-10-28 | Martz Joel D. | Hybrid microporous membrane |
| US7494465B2 (en) | 2004-07-13 | 2009-02-24 | Dexcom, Inc. | Transcutaneous analyte sensor |
| WO2005084257A2 (en) | 2004-02-26 | 2005-09-15 | Vpn Solutions, Llc | Composite thin-film glucose sensor |
| US20070027383A1 (en) | 2004-07-01 | 2007-02-01 | Peyser Thomas A | Patches, systems, and methods for non-invasive glucose measurement |
| AU2005262444A1 (en) | 2004-07-01 | 2006-01-19 | Vivomedical, Inc. | Non-invasive glucose measurement |
| US8989833B2 (en) | 2004-07-13 | 2015-03-24 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US8512243B2 (en) | 2005-09-30 | 2013-08-20 | Abbott Diabetes Care Inc. | Integrated introducer and transmitter assembly and methods of use |
| US20070027381A1 (en) | 2005-07-29 | 2007-02-01 | Therasense, Inc. | Inserter and methods of use |
| US9521968B2 (en) | 2005-09-30 | 2016-12-20 | Abbott Diabetes Care Inc. | Analyte sensor retention mechanism and methods of use |
| US20070179373A1 (en) | 2005-12-22 | 2007-08-02 | Provex Technologies, Llc. | Integrated patch and assay device with visual detection means |
| JP2006250949A (ja) | 2006-05-15 | 2006-09-21 | Japan Science & Technology Agency | 皮膚表面に存在するグルコース測定方法 |
-
2005
- 2005-06-22 AU AU2005262444A patent/AU2005262444A1/en not_active Abandoned
- 2005-06-22 CN CN200910145623A patent/CN101623199A/zh active Pending
- 2005-06-22 JP JP2007519286A patent/JP2008504881A/ja not_active Withdrawn
- 2005-06-22 KR KR1020077000105A patent/KR20070043768A/ko not_active Withdrawn
- 2005-06-22 MX MXPA06014896A patent/MXPA06014896A/es not_active Application Discontinuation
- 2005-06-22 CN CNB2005800250985A patent/CN100512747C/zh not_active Expired - Fee Related
- 2005-06-22 WO PCT/US2005/022139 patent/WO2006007472A2/en not_active Ceased
- 2005-06-22 EP EP05762354A patent/EP1776035A2/en not_active Withdrawn
- 2005-06-22 CA CA002572313A patent/CA2572313A1/en not_active Abandoned
- 2005-06-22 US US11/159,587 patent/US7725149B2/en not_active Expired - Fee Related
-
2006
- 2006-12-13 IL IL180034A patent/IL180034A0/en unknown
-
2009
- 2009-09-24 JP JP2009219800A patent/JP2010017572A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| US20060004271A1 (en) | 2006-01-05 |
| WO2006007472A3 (en) | 2006-06-08 |
| CA2572313A1 (en) | 2006-01-19 |
| JP2008504881A (ja) | 2008-02-21 |
| KR20070043768A (ko) | 2007-04-25 |
| CN101623199A (zh) | 2010-01-13 |
| US7725149B2 (en) | 2010-05-25 |
| IL180034A0 (en) | 2007-05-15 |
| EP1776035A2 (en) | 2007-04-25 |
| CN100512747C (zh) | 2009-07-15 |
| WO2006007472A2 (en) | 2006-01-19 |
| CN101005798A (zh) | 2007-07-25 |
| WO2006007472B1 (en) | 2006-07-06 |
| AU2005262444A1 (en) | 2006-01-19 |
| JP2010017572A (ja) | 2010-01-28 |
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| FA | Abandonment or withdrawal |