MXPA03000619A - Compuestos de carbamato para utilizarlos en la prevencion o el tratamiento del dolor y la cefalea neuropaticos y el dolor asociado con la migrana. - Google Patents

Compuestos de carbamato para utilizarlos en la prevencion o el tratamiento del dolor y la cefalea neuropaticos y el dolor asociado con la migrana.

Info

Publication number
MXPA03000619A
MXPA03000619A MXPA03000619A MXPA03000619A MXPA03000619A MX PA03000619 A MXPA03000619 A MX PA03000619A MX PA03000619 A MXPA03000619 A MX PA03000619A MX PA03000619 A MXPA03000619 A MX PA03000619A MX PA03000619 A MXPA03000619 A MX PA03000619A
Authority
MX
Mexico
Prior art keywords
pain
cluster
preventing
migraine headache
treating neuropathic
Prior art date
Application number
MXPA03000619A
Other languages
English (en)
Inventor
Katherine E Rogers
Original Assignee
Johnson & Johnson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22820176&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MXPA03000619(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Johnson & Johnson filed Critical Johnson & Johnson
Publication of MXPA03000619A publication Critical patent/MXPA03000619A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Esta invencion se refiere a un metodo para prevenir o tratar el dolor y la cefalea neuropaticos y el dolor asociado con migrana, que comprende administrar a un sujeto que tenga necesidad del mismo una cantidad terapeuticamente efectiva de un enantiomero de la formula (I) sustancialmente libre de otros enantiomeros o una mezcla enantiomerica en donde predomina un enantiomero de la formula (I): (ver formula) en donde el fenilo se sustituye en X con de uno a cinco atomos de alogeno seleccionados independientemente del grupo que consiste en fluor, cloro, bromo y yodo; y R1 y R2 se seleccionan independientemente del grupo que consiste en hidrogeno y alquilo de C1-C4; en donde el alquilo de C1-C4 se sustituye opcionalmente con fenilo (en donde el fenilo se sustituye opcionalmente con sustituyentes seleccionados en forma independiente del grupo que consiste en hidrogeno, halogeno, alquilo de C1-C4 alcoxi de C1-C4, amino, nitro, y ciano).
MXPA03000619A 2000-07-21 2001-07-16 Compuestos de carbamato para utilizarlos en la prevencion o el tratamiento del dolor y la cefalea neuropaticos y el dolor asociado con la migrana. MXPA03000619A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21965700P 2000-07-21 2000-07-21
PCT/US2001/022322 WO2002007822A2 (en) 2000-07-21 2001-07-16 Carbamate compounds for use in preventing or treating neuropathic pain and cluster and migraine headache-associated pain

Publications (1)

Publication Number Publication Date
MXPA03000619A true MXPA03000619A (es) 2004-07-30

Family

ID=22820176

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03000619A MXPA03000619A (es) 2000-07-21 2001-07-16 Compuestos de carbamato para utilizarlos en la prevencion o el tratamiento del dolor y la cefalea neuropaticos y el dolor asociado con la migrana.

Country Status (28)

Country Link
US (4) US20020107283A1 (es)
EP (1) EP1305082B1 (es)
JP (1) JP5271473B2 (es)
KR (1) KR100792814B1 (es)
CN (1) CN1250213C (es)
AT (1) ATE267629T1 (es)
AU (2) AU7349301A (es)
BG (1) BG107529A (es)
BR (1) BR0112713A (es)
CA (1) CA2416819C (es)
CZ (1) CZ2003445A3 (es)
DE (1) DE60103546T2 (es)
DK (1) DK1305082T3 (es)
EA (1) EA005648B1 (es)
ES (1) ES2221651T3 (es)
HU (1) HUP0302940A3 (es)
IL (2) IL154052A0 (es)
MX (1) MXPA03000619A (es)
MY (1) MY127317A (es)
NO (1) NO330055B1 (es)
NZ (1) NZ523851A (es)
PL (1) PL365701A1 (es)
PT (1) PT1305082E (es)
SK (1) SK1962003A3 (es)
TR (1) TR200401511T4 (es)
UA (1) UA74195C2 (es)
WO (1) WO2002007822A2 (es)
ZA (1) ZA200301403B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4276838B2 (ja) 2001-02-27 2009-06-10 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド 疼痛(pain)の治療における使用のためのカルバメート化合物
HUP0401367A2 (hu) 2001-07-16 2004-12-28 Ortho-Mcneil Pharmaceutical, Inc. Karbamátvegyületek alkalmazása neuropátiás fájdalom, valamint cluster és migrénes fejfájással társuló fájdalom megelőzésére vagy kezelésére
PT1406606E (pt) * 2001-07-16 2007-03-30 Ortho Mcneil Pharm Inc Compostos de carbamato para utilização na prevenção ou tratamento da dor neuropática e da dor associada a cefaleia em salvas e enxaqueca
US20040087642A1 (en) * 2002-10-24 2004-05-06 Zeldis Jerome B. Methods of using and compositions comprising a JNK inhibitor for the treatment, prevention, management and/or modification of pain
WO2004054608A2 (en) * 2002-12-12 2004-07-01 Agennix Incorporated Lactoferrin in the reduction of pain
US7183381B2 (en) * 2004-10-26 2007-02-27 Agennix, Inc. Composition of lactoferrin related peptides and uses thereof
US7846968B2 (en) * 2005-01-20 2010-12-07 Janssen Pharmaceutica, N.V. Methods for QT interval control
EP2476434A1 (en) 2006-03-30 2012-07-18 GlaxoSmithKline Biologicals S.A. Immunogenic composition
US20080194860A1 (en) * 2006-10-10 2008-08-14 Transform Pharmaceuticals, Inc. Novel crystal of (s)-(+)-2-(2-chlorophenyl)-2-hydroxy-ethyl carbamate
US8609849B1 (en) 2010-11-30 2013-12-17 Fox Chase Chemical Diversity Center, Inc. Hydroxylated sulfamides exhibiting neuroprotective action and their method of use
US20150057351A1 (en) * 2013-08-22 2015-02-26 Sucampo Ag Method for treating neuropathic pain

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3278380A (en) * 1962-02-06 1966-10-11 Armour Pharma Methods of calming employing diphenyl hydroxy carbamate compounds
US3265728A (en) 1962-07-18 1966-08-09 Armour Pharma Substituted phenethyl carbamates
HU191549B (en) * 1984-04-11 1987-03-30 Richter Gedeon Vegyeszet Process for producing 1-/6-/2 comma above-substituted-5 comma above, 6 comma above, 7 comma above, 8 comma above-tetrahydro-4 comma above-oxo-quinazolino//-3,4-dihydro-6,7-disubstituted-isoquinoline derivatives
US4868190A (en) * 1988-12-27 1989-09-19 Hoechst-Roussel Pharmaceuticals, Inc. N-pyridinyl-9H-carbazol-9-amines
GB9518027D0 (en) * 1995-09-05 1995-11-08 Wellcome Found Pharmacologically active compound
US5698588A (en) * 1996-01-16 1997-12-16 Yukong Limited Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol
WO1998055474A1 (fr) * 1997-06-05 1998-12-10 Sanofi-Synthelabo Derives de 5-naphtalen-1-yl-1,3-dioxane, leur preparation et leur application en therapeutique
RU2302240C2 (ru) * 2001-02-27 2007-07-10 Орто-Макнейл Фармасьютикал, Инк. Производные карбаматов для предотвращения или лечения психотических нарушений
CZ20032299A3 (cs) * 2001-02-27 2004-08-18 Ortho@Mcneilápharmaceuticalźáinc Léčivo pro prevenci nebo léčbu motorických poruch
EP1408953B1 (en) * 2001-02-27 2006-04-26 Ortho-Mcneil Pharmaceutical, Inc. Carbamate compounds for use in preventing or treating bipolar disorder

Also Published As

Publication number Publication date
DK1305082T3 (da) 2004-09-13
KR100792814B1 (ko) 2008-01-14
CA2416819A1 (en) 2002-01-31
HUP0302940A3 (en) 2012-02-28
US20020107283A1 (en) 2002-08-08
NO20030299D0 (no) 2003-01-20
NO20030299L (no) 2003-03-12
MY127317A (en) 2006-11-30
WO2002007822A2 (en) 2002-01-31
US20090281179A1 (en) 2009-11-12
HUP0302940A2 (hu) 2003-12-29
ES2221651T3 (es) 2005-01-01
AU2001273493B2 (en) 2005-08-11
CA2416819C (en) 2011-03-22
DE60103546D1 (de) 2004-07-01
NZ523851A (en) 2004-09-24
ATE267629T1 (de) 2004-06-15
WO2002007822A3 (en) 2002-05-30
IL154052A (en) 2008-07-08
EP1305082B1 (en) 2004-05-26
JP5271473B2 (ja) 2013-08-21
AU7349301A (en) 2002-02-05
JP2004504362A (ja) 2004-02-12
PL365701A1 (en) 2005-01-10
NO330055B1 (no) 2011-02-14
DE60103546T2 (de) 2005-06-09
BR0112713A (pt) 2003-07-22
BG107529A (bg) 2003-09-30
KR20030022300A (ko) 2003-03-15
US20060183795A1 (en) 2006-08-17
US20040266866A1 (en) 2004-12-30
CN1250213C (zh) 2006-04-12
ZA200301403B (en) 2004-06-15
CN1458853A (zh) 2003-11-26
PT1305082E (pt) 2004-09-30
IL154052A0 (en) 2003-07-31
UA74195C2 (uk) 2005-11-15
EA005648B1 (ru) 2005-04-28
EP1305082A2 (en) 2003-05-02
EA200300042A1 (ru) 2003-06-26
SK1962003A3 (en) 2004-08-03
TR200401511T4 (tr) 2004-08-23
CZ2003445A3 (cs) 2004-08-18

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