MXPA03000619A - Compuestos de carbamato para utilizarlos en la prevencion o el tratamiento del dolor y la cefalea neuropaticos y el dolor asociado con la migrana. - Google Patents
Compuestos de carbamato para utilizarlos en la prevencion o el tratamiento del dolor y la cefalea neuropaticos y el dolor asociado con la migrana.Info
- Publication number
- MXPA03000619A MXPA03000619A MXPA03000619A MXPA03000619A MXPA03000619A MX PA03000619 A MXPA03000619 A MX PA03000619A MX PA03000619 A MXPA03000619 A MX PA03000619A MX PA03000619 A MXPA03000619 A MX PA03000619A MX PA03000619 A MXPA03000619 A MX PA03000619A
- Authority
- MX
- Mexico
- Prior art keywords
- pain
- cluster
- preventing
- migraine headache
- treating neuropathic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Esta invencion se refiere a un metodo para prevenir o tratar el dolor y la cefalea neuropaticos y el dolor asociado con migrana, que comprende administrar a un sujeto que tenga necesidad del mismo una cantidad terapeuticamente efectiva de un enantiomero de la formula (I) sustancialmente libre de otros enantiomeros o una mezcla enantiomerica en donde predomina un enantiomero de la formula (I): (ver formula) en donde el fenilo se sustituye en X con de uno a cinco atomos de alogeno seleccionados independientemente del grupo que consiste en fluor, cloro, bromo y yodo; y R1 y R2 se seleccionan independientemente del grupo que consiste en hidrogeno y alquilo de C1-C4; en donde el alquilo de C1-C4 se sustituye opcionalmente con fenilo (en donde el fenilo se sustituye opcionalmente con sustituyentes seleccionados en forma independiente del grupo que consiste en hidrogeno, halogeno, alquilo de C1-C4 alcoxi de C1-C4, amino, nitro, y ciano).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US21965700P | 2000-07-21 | 2000-07-21 | |
PCT/US2001/022322 WO2002007822A2 (en) | 2000-07-21 | 2001-07-16 | Carbamate compounds for use in preventing or treating neuropathic pain and cluster and migraine headache-associated pain |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA03000619A true MXPA03000619A (es) | 2004-07-30 |
Family
ID=22820176
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA03000619A MXPA03000619A (es) | 2000-07-21 | 2001-07-16 | Compuestos de carbamato para utilizarlos en la prevencion o el tratamiento del dolor y la cefalea neuropaticos y el dolor asociado con la migrana. |
Country Status (28)
Country | Link |
---|---|
US (4) | US20020107283A1 (es) |
EP (1) | EP1305082B1 (es) |
JP (1) | JP5271473B2 (es) |
KR (1) | KR100792814B1 (es) |
CN (1) | CN1250213C (es) |
AT (1) | ATE267629T1 (es) |
AU (2) | AU7349301A (es) |
BG (1) | BG107529A (es) |
BR (1) | BR0112713A (es) |
CA (1) | CA2416819C (es) |
CZ (1) | CZ2003445A3 (es) |
DE (1) | DE60103546T2 (es) |
DK (1) | DK1305082T3 (es) |
EA (1) | EA005648B1 (es) |
ES (1) | ES2221651T3 (es) |
HU (1) | HUP0302940A3 (es) |
IL (2) | IL154052A0 (es) |
MX (1) | MXPA03000619A (es) |
MY (1) | MY127317A (es) |
NO (1) | NO330055B1 (es) |
NZ (1) | NZ523851A (es) |
PL (1) | PL365701A1 (es) |
PT (1) | PT1305082E (es) |
SK (1) | SK1962003A3 (es) |
TR (1) | TR200401511T4 (es) |
UA (1) | UA74195C2 (es) |
WO (1) | WO2002007822A2 (es) |
ZA (1) | ZA200301403B (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4276838B2 (ja) | 2001-02-27 | 2009-06-10 | オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド | 疼痛(pain)の治療における使用のためのカルバメート化合物 |
HUP0401367A2 (hu) | 2001-07-16 | 2004-12-28 | Ortho-Mcneil Pharmaceutical, Inc. | Karbamátvegyületek alkalmazása neuropátiás fájdalom, valamint cluster és migrénes fejfájással társuló fájdalom megelőzésére vagy kezelésére |
PT1406606E (pt) * | 2001-07-16 | 2007-03-30 | Ortho Mcneil Pharm Inc | Compostos de carbamato para utilização na prevenção ou tratamento da dor neuropática e da dor associada a cefaleia em salvas e enxaqueca |
US20040087642A1 (en) * | 2002-10-24 | 2004-05-06 | Zeldis Jerome B. | Methods of using and compositions comprising a JNK inhibitor for the treatment, prevention, management and/or modification of pain |
WO2004054608A2 (en) * | 2002-12-12 | 2004-07-01 | Agennix Incorporated | Lactoferrin in the reduction of pain |
US7183381B2 (en) * | 2004-10-26 | 2007-02-27 | Agennix, Inc. | Composition of lactoferrin related peptides and uses thereof |
US7846968B2 (en) * | 2005-01-20 | 2010-12-07 | Janssen Pharmaceutica, N.V. | Methods for QT interval control |
EP2476434A1 (en) | 2006-03-30 | 2012-07-18 | GlaxoSmithKline Biologicals S.A. | Immunogenic composition |
US20080194860A1 (en) * | 2006-10-10 | 2008-08-14 | Transform Pharmaceuticals, Inc. | Novel crystal of (s)-(+)-2-(2-chlorophenyl)-2-hydroxy-ethyl carbamate |
US8609849B1 (en) | 2010-11-30 | 2013-12-17 | Fox Chase Chemical Diversity Center, Inc. | Hydroxylated sulfamides exhibiting neuroprotective action and their method of use |
US20150057351A1 (en) * | 2013-08-22 | 2015-02-26 | Sucampo Ag | Method for treating neuropathic pain |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3278380A (en) * | 1962-02-06 | 1966-10-11 | Armour Pharma | Methods of calming employing diphenyl hydroxy carbamate compounds |
US3265728A (en) | 1962-07-18 | 1966-08-09 | Armour Pharma | Substituted phenethyl carbamates |
HU191549B (en) * | 1984-04-11 | 1987-03-30 | Richter Gedeon Vegyeszet | Process for producing 1-/6-/2 comma above-substituted-5 comma above, 6 comma above, 7 comma above, 8 comma above-tetrahydro-4 comma above-oxo-quinazolino//-3,4-dihydro-6,7-disubstituted-isoquinoline derivatives |
US4868190A (en) * | 1988-12-27 | 1989-09-19 | Hoechst-Roussel Pharmaceuticals, Inc. | N-pyridinyl-9H-carbazol-9-amines |
GB9518027D0 (en) * | 1995-09-05 | 1995-11-08 | Wellcome Found | Pharmacologically active compound |
US5698588A (en) * | 1996-01-16 | 1997-12-16 | Yukong Limited | Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol |
WO1998055474A1 (fr) * | 1997-06-05 | 1998-12-10 | Sanofi-Synthelabo | Derives de 5-naphtalen-1-yl-1,3-dioxane, leur preparation et leur application en therapeutique |
RU2302240C2 (ru) * | 2001-02-27 | 2007-07-10 | Орто-Макнейл Фармасьютикал, Инк. | Производные карбаматов для предотвращения или лечения психотических нарушений |
CZ20032299A3 (cs) * | 2001-02-27 | 2004-08-18 | Ortho@Mcneilápharmaceuticalźáinc | Léčivo pro prevenci nebo léčbu motorických poruch |
EP1408953B1 (en) * | 2001-02-27 | 2006-04-26 | Ortho-Mcneil Pharmaceutical, Inc. | Carbamate compounds for use in preventing or treating bipolar disorder |
-
2001
- 2001-07-16 AU AU7349301A patent/AU7349301A/xx active Pending
- 2001-07-16 AT AT01952773T patent/ATE267629T1/de not_active IP Right Cessation
- 2001-07-16 AU AU2001273493A patent/AU2001273493B2/en not_active Ceased
- 2001-07-16 KR KR1020037000914A patent/KR100792814B1/ko active IP Right Grant
- 2001-07-16 CZ CZ2003445A patent/CZ2003445A3/cs unknown
- 2001-07-16 PL PL01365701A patent/PL365701A1/xx not_active Application Discontinuation
- 2001-07-16 MX MXPA03000619A patent/MXPA03000619A/es active IP Right Grant
- 2001-07-16 ES ES01952773T patent/ES2221651T3/es not_active Expired - Lifetime
- 2001-07-16 CA CA2416819A patent/CA2416819C/en not_active Expired - Fee Related
- 2001-07-16 CN CNB01815798XA patent/CN1250213C/zh not_active Expired - Fee Related
- 2001-07-16 DK DK01952773T patent/DK1305082T3/da active
- 2001-07-16 SK SK196-2003A patent/SK1962003A3/sk unknown
- 2001-07-16 BR BR0112713-6A patent/BR0112713A/pt not_active Application Discontinuation
- 2001-07-16 JP JP2002513552A patent/JP5271473B2/ja not_active Expired - Lifetime
- 2001-07-16 PT PT01952773T patent/PT1305082E/pt unknown
- 2001-07-16 EP EP01952773A patent/EP1305082B1/en not_active Expired - Lifetime
- 2001-07-16 UA UA2003010559A patent/UA74195C2/uk unknown
- 2001-07-16 TR TR2004/01511T patent/TR200401511T4/xx unknown
- 2001-07-16 WO PCT/US2001/022322 patent/WO2002007822A2/en active IP Right Grant
- 2001-07-16 EA EA200300042A patent/EA005648B1/ru not_active IP Right Cessation
- 2001-07-16 IL IL15405201A patent/IL154052A0/xx unknown
- 2001-07-16 DE DE60103546T patent/DE60103546T2/de not_active Expired - Lifetime
- 2001-07-16 HU HU0302940A patent/HUP0302940A3/hu unknown
- 2001-07-16 NZ NZ523851A patent/NZ523851A/en unknown
- 2001-07-16 US US09/906,251 patent/US20020107283A1/en not_active Abandoned
- 2001-07-20 MY MYPI20013443 patent/MY127317A/en unknown
-
2003
- 2003-01-20 NO NO20030299A patent/NO330055B1/no not_active IP Right Cessation
- 2003-01-20 IL IL154052A patent/IL154052A/en unknown
- 2003-02-05 BG BG107529A patent/BG107529A/bg unknown
- 2003-02-20 ZA ZA200301403A patent/ZA200301403B/en unknown
-
2004
- 2004-06-15 US US10/868,633 patent/US20040266866A1/en not_active Abandoned
-
2005
- 2005-02-18 US US11/194,876 patent/US20060183795A1/en not_active Abandoned
-
2009
- 2009-07-20 US US12/505,765 patent/US20090281179A1/en not_active Abandoned
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration |