MXPA02004774A - Compuestos de fosfato de glucosaminida de aminoalquilo y su uso como adyuvante e inmunoefectores. - Google Patents
Compuestos de fosfato de glucosaminida de aminoalquilo y su uso como adyuvante e inmunoefectores.Info
- Publication number
- MXPA02004774A MXPA02004774A MXPA02004774A MXPA02004774A MXPA02004774A MX PA02004774 A MXPA02004774 A MX PA02004774A MX PA02004774 A MXPA02004774 A MX PA02004774A MX PA02004774 A MXPA02004774 A MX PA02004774A MX PA02004774 A MXPA02004774 A MX PA02004774A
- Authority
- MX
- Mexico
- Prior art keywords
- mmol
- configuration
- phosphono
- nmr
- compound according
- Prior art date
Links
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- 229910052760 oxygen Inorganic materials 0.000 claims description 37
- 229960005486 vaccine Drugs 0.000 claims description 35
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- 108091007433 antigens Proteins 0.000 claims description 31
- 239000000427 antigen Substances 0.000 claims description 30
- 125000004432 carbon atom Chemical group C* 0.000 claims description 22
- 125000001476 phosphono group Chemical group [H]OP(*)(=O)O[H] 0.000 claims description 21
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims description 17
- 229910052739 hydrogen Inorganic materials 0.000 claims description 16
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- 150000004665 fatty acids Chemical group 0.000 claims description 14
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims description 12
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- PXLIDIMHPNPGMH-UHFFFAOYSA-N sodium chromate Chemical compound [Na+].[Na+].[O-][Cr]([O-])(=O)=O PXLIDIMHPNPGMH-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
- C07H13/06—Fatty acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/439,839 US6303347B1 (en) | 1997-05-08 | 1999-11-12 | Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors |
| PCT/US2000/031340 WO2001034617A2 (en) | 1999-11-12 | 2000-11-13 | Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA02004774A true MXPA02004774A (es) | 2003-01-28 |
Family
ID=23746342
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA02004774A MXPA02004774A (es) | 1999-11-12 | 2000-11-13 | Compuestos de fosfato de glucosaminida de aminoalquilo y su uso como adyuvante e inmunoefectores. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6303347B1 (https=) |
| EP (1) | EP1230250A2 (https=) |
| JP (1) | JP2003514783A (https=) |
| CN (1) | CN1409720A (https=) |
| AR (1) | AR026443A1 (https=) |
| BR (1) | BR0015501A (https=) |
| CA (1) | CA2391299A1 (https=) |
| CO (1) | CO5261562A1 (https=) |
| MX (1) | MXPA02004774A (https=) |
| NO (1) | NO20022207L (https=) |
| NZ (1) | NZ518860A (https=) |
| WO (1) | WO2001034617A2 (https=) |
Families Citing this family (196)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7063967B2 (en) * | 1997-05-08 | 2006-06-20 | Corixa Corporation | Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors |
| US7541020B2 (en) * | 1997-05-08 | 2009-06-02 | Corixa Corporation | Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors |
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| US4912094B1 (en) | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
| US6113918A (en) | 1997-05-08 | 2000-09-05 | Ribi Immunochem Research, Inc. | Aminoalkyl glucosamine phosphate compounds and their use as adjuvants and immunoeffectors |
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2000
- 2000-11-10 AR ARP000105962A patent/AR026443A1/es not_active Application Discontinuation
- 2000-11-10 CO CO00085801A patent/CO5261562A1/es not_active Application Discontinuation
- 2000-11-13 EP EP00982119A patent/EP1230250A2/en not_active Withdrawn
- 2000-11-13 CA CA002391299A patent/CA2391299A1/en not_active Abandoned
- 2000-11-13 WO PCT/US2000/031340 patent/WO2001034617A2/en not_active Ceased
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- 2000-11-13 BR BR0015501-2A patent/BR0015501A/pt not_active IP Right Cessation
- 2000-11-13 MX MXPA02004774A patent/MXPA02004774A/es active IP Right Grant
- 2000-11-13 JP JP2001537329A patent/JP2003514783A/ja active Pending
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2002
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| NO20022207L (no) | 2002-07-10 |
| CN1409720A (zh) | 2003-04-09 |
| BR0015501A (pt) | 2003-02-25 |
| WO2001034617A3 (en) | 2001-11-08 |
| AR026443A1 (es) | 2003-02-12 |
| JP2003514783A (ja) | 2003-04-22 |
| NO20022207D0 (no) | 2002-05-08 |
| NZ518860A (en) | 2004-11-26 |
| WO2001034617A2 (en) | 2001-05-17 |
| US6303347B1 (en) | 2001-10-16 |
| CA2391299A1 (en) | 2001-05-17 |
| CO5261562A1 (es) | 2003-03-31 |
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