MX9704486A - Benzoil-guanidinas sustituidas en orto, procedimiento para su preparacion, su utilizacion como medicamento o agente de diagnostico, asi como medicamento que las contiene. - Google Patents
Benzoil-guanidinas sustituidas en orto, procedimiento para su preparacion, su utilizacion como medicamento o agente de diagnostico, asi como medicamento que las contiene.Info
- Publication number
- MX9704486A MX9704486A MX9704486A MX9704486A MX9704486A MX 9704486 A MX9704486 A MX 9704486A MX 9704486 A MX9704486 A MX 9704486A MX 9704486 A MX9704486 A MX 9704486A MX 9704486 A MX9704486 A MX 9704486A
- Authority
- MX
- Mexico
- Prior art keywords
- medicament
- orto
- guanidines
- compounds
- utilization
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Las benzoil-guanidinas de la formula I, en la que R(1) hasta R(4) tienen los significados dados en las reivindicaciones, son valiosos medicamentos antiarrítmicos con una componente cardioprotectora, también para la prevencion de lesiones inducidas isquémicamente, especialmente en el caso de la provocacion de arritmias cardíacas inducidas isquémicamente. Estas, a causa de la inhibicion del mecanismo de intercambio celular entre Na+ y H+, se utilizan para el tratamiento de lesiones agudas o cronicas inducidas por isquemia. Además de ello se distinguen por un intenso efecto inhibidor sobre las proliferaciones de células. Son apropiados para evitar la génesis de la hipertension sanguínea.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19624178A DE19624178A1 (de) | 1996-06-18 | 1996-06-18 | Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9704486A true MX9704486A (es) | 1997-12-31 |
Family
ID=7797197
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9704486A MX9704486A (es) | 1996-06-18 | 1997-06-17 | Benzoil-guanidinas sustituidas en orto, procedimiento para su preparacion, su utilizacion como medicamento o agente de diagnostico, asi como medicamento que las contiene. |
Country Status (31)
Country | Link |
---|---|
US (1) | US6001881A (es) |
EP (1) | EP0814077B1 (es) |
JP (1) | JP3977897B2 (es) |
KR (1) | KR100498799B1 (es) |
CN (1) | CN1064676C (es) |
AR (1) | AR012536A1 (es) |
AT (1) | ATE191469T1 (es) |
AU (1) | AU711734B2 (es) |
BR (1) | BR9703617A (es) |
CA (1) | CA2207886A1 (es) |
CZ (1) | CZ291848B6 (es) |
DE (2) | DE19624178A1 (es) |
DK (1) | DK0814077T3 (es) |
ES (1) | ES2146049T3 (es) |
GR (1) | GR3033299T3 (es) |
HR (1) | HRP970332B1 (es) |
HU (1) | HUP9701057A3 (es) |
ID (1) | ID17321A (es) |
IL (1) | IL121085A0 (es) |
MX (1) | MX9704486A (es) |
MY (1) | MY117304A (es) |
NO (1) | NO307928B1 (es) |
NZ (1) | NZ328100A (es) |
PL (1) | PL185756B1 (es) |
PT (1) | PT814077E (es) |
RU (1) | RU2193025C2 (es) |
SI (1) | SI0814077T1 (es) |
SK (1) | SK282351B6 (es) |
TR (1) | TR199700508A2 (es) |
TW (1) | TW374759B (es) |
ZA (1) | ZA975312B (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19608161A1 (de) * | 1996-03-04 | 1997-09-11 | Hoechst Ag | Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
DE19713427A1 (de) * | 1997-04-01 | 1998-10-08 | Hoechst Ag | Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
DE10001879A1 (de) * | 2000-01-19 | 2001-07-19 | Aventis Pharma Gmbh | Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
US6641811B1 (en) * | 2000-02-10 | 2003-11-04 | Cornell Research Foundation, Inc. | Use of angiotensin II inhibitors to prevent malignancies associated with immunosuppression |
US7828840B2 (en) * | 2007-11-15 | 2010-11-09 | Med Institute, Inc. | Medical devices and methods for local delivery of angiotensin II type 2 receptor antagonists |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4318756A1 (de) * | 1993-06-05 | 1994-12-08 | Hoechst Ag | Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
DE4328869A1 (de) * | 1993-08-27 | 1995-03-02 | Hoechst Ag | Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
DE4430213A1 (de) * | 1994-08-28 | 1996-02-29 | Merck Patent Gmbh | Arylbenzoylguanidine |
DE4430916A1 (de) * | 1994-08-31 | 1996-03-07 | Merck Patent Gmbh | Alkyl-benzoylguanidin-Derivate |
DE4430861A1 (de) * | 1994-08-31 | 1996-03-07 | Merck Patent Gmbh | Heterocyclyl-benzoylguanidine |
DE19608162A1 (de) * | 1996-03-04 | 1997-09-11 | Hoechst Ag | Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
-
1996
- 1996-06-18 DE DE19624178A patent/DE19624178A1/de not_active Withdrawn
-
1997
- 1997-06-03 PL PL97320326A patent/PL185756B1/pl not_active IP Right Cessation
- 1997-06-04 US US08/868,750 patent/US6001881A/en not_active Expired - Lifetime
- 1997-06-12 EP EP97109546A patent/EP0814077B1/de not_active Expired - Lifetime
- 1997-06-12 ES ES97109546T patent/ES2146049T3/es not_active Expired - Lifetime
- 1997-06-12 SI SI9730060T patent/SI0814077T1/xx unknown
- 1997-06-12 PT PT97109546T patent/PT814077E/pt unknown
- 1997-06-12 AT AT97109546T patent/ATE191469T1/de not_active IP Right Cessation
- 1997-06-12 DK DK97109546T patent/DK0814077T3/da active
- 1997-06-12 DE DE59701388T patent/DE59701388D1/de not_active Expired - Lifetime
- 1997-06-13 AR ARP970102605A patent/AR012536A1/es unknown
- 1997-06-16 ID IDP972057A patent/ID17321A/id unknown
- 1997-06-16 IL IL12108597A patent/IL121085A0/xx not_active IP Right Cessation
- 1997-06-16 SK SK766-97A patent/SK282351B6/sk unknown
- 1997-06-16 TW TW086108285A patent/TW374759B/zh active
- 1997-06-16 MY MYPI97002694A patent/MY117304A/en unknown
- 1997-06-16 NZ NZ328100A patent/NZ328100A/en unknown
- 1997-06-16 AU AU24942/97A patent/AU711734B2/en not_active Ceased
- 1997-06-16 TR TR97/00508A patent/TR199700508A2/xx unknown
- 1997-06-16 CN CN97113806A patent/CN1064676C/zh not_active Expired - Fee Related
- 1997-06-17 HU HU9701057A patent/HUP9701057A3/hu unknown
- 1997-06-17 RU RU97109528/04A patent/RU2193025C2/ru not_active IP Right Cessation
- 1997-06-17 NO NO972793A patent/NO307928B1/no unknown
- 1997-06-17 MX MX9704486A patent/MX9704486A/es not_active IP Right Cessation
- 1997-06-17 ZA ZA9705312A patent/ZA975312B/xx unknown
- 1997-06-17 CZ CZ19971887A patent/CZ291848B6/cs not_active IP Right Cessation
- 1997-06-17 JP JP15938297A patent/JP3977897B2/ja not_active Expired - Fee Related
- 1997-06-17 HR HR19624178.2 patent/HRP970332B1/xx not_active IP Right Cessation
- 1997-06-17 CA CA002207886A patent/CA2207886A1/en not_active Abandoned
- 1997-06-18 BR BR9703617A patent/BR9703617A/pt not_active Application Discontinuation
- 1997-06-18 KR KR1019970025282A patent/KR100498799B1/ko not_active IP Right Cessation
-
2000
- 2000-04-21 GR GR20000400981T patent/GR3033299T3/el not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration | ||
MM | Annulment or lapse due to non-payment of fees |