MX9306923A - Procedimiento para la preparacion de un acido 1,3-oxazolidin-5-carboxilico. - Google Patents

Procedimiento para la preparacion de un acido 1,3-oxazolidin-5-carboxilico.

Info

Publication number
MX9306923A
MX9306923A MX9306923A MX9306923A MX9306923A MX 9306923 A MX9306923 A MX 9306923A MX 9306923 A MX9306923 A MX 9306923A MX 9306923 A MX9306923 A MX 9306923A MX 9306923 A MX9306923 A MX 9306923A
Authority
MX
Mexico
Prior art keywords
radical
pct
date
oxazolidin
carboxylic acid
Prior art date
Application number
MX9306923A
Other languages
English (en)
Inventor
Jean-Noel Denis
Andrew Greene
Alice Kanazawa
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of MX9306923A publication Critical patent/MX9306923A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invención se refiere a un procedimiento para la preparación de un ácido 1,3-oxazolidin 5-carboxílico de la fórmula general (I) a partir de un producto de la fórmula general (II). En las fórmulas generales (I) y (II): Ar representa un radical arilo, R1 representa un radical benzoilo o un radical R2-O-CO- en el cual R2 representa un radical alquilo, alquenilo, alquinilo, cicloalquilo, cicloalquenilo, bicicloalquilo, fenilo o heterociclilo. Fen representa un radical fenilo eventualmente sustituido, X representa el residuo o resto de una base orgánica, ópticamente activa o un radical alcoxi eventualmente sustituido por un radical fenilo. Los ácidos de la fórmula general (I) son particularmente útiles para preparar el taxol, el Taxótero o sus análogos los cuales presentan excelentes propiedades antitumorígenas y antileucémicas.
MX9306923A 1992-11-20 1993-11-05 Procedimiento para la preparacion de un acido 1,3-oxazolidin-5-carboxilico. MX9306923A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9213939A FR2698361B1 (fr) 1992-11-20 1992-11-20 Procédé de préparation d'un acide oxazolidine-1,3 carboxylique-5.

Publications (1)

Publication Number Publication Date
MX9306923A true MX9306923A (es) 1994-06-30

Family

ID=9435720

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9306923A MX9306923A (es) 1992-11-20 1993-11-05 Procedimiento para la preparacion de un acido 1,3-oxazolidin-5-carboxilico.

Country Status (25)

Country Link
US (1) US5811550A (es)
EP (1) EP0669915B1 (es)
JP (1) JP3648554B2 (es)
KR (1) KR100330317B1 (es)
AT (1) ATE154600T1 (es)
AU (1) AU679195B2 (es)
CA (1) CA2149637C (es)
CZ (1) CZ283525B6 (es)
DE (1) DE69311736T2 (es)
DK (1) DK0669915T3 (es)
ES (1) ES2105596T3 (es)
FI (1) FI119289B (es)
FR (2) FR2698361B1 (es)
GR (1) GR3023803T3 (es)
HU (1) HU221164B1 (es)
MX (1) MX9306923A (es)
NO (1) NO304786B1 (es)
NZ (1) NZ257875A (es)
OA (1) OA10155A (es)
PL (1) PL176659B1 (es)
RU (1) RU2114834C1 (es)
SK (2) SK280964B6 (es)
TW (1) TW305839B (es)
WO (1) WO1994012482A1 (es)
ZA (1) ZA938588B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2706457B1 (fr) * 1993-06-16 1995-07-28 Rhone Poulenc Rorer Sa Procédé de préparation d'un acide oxazolidinecarboxylique utile pour préparer des taxoïdes thérapeutiquement actifs.
WO2002066448A1 (en) * 2001-02-20 2002-08-29 Dabur India Limited Method of preparation of paclitaxel (taxol) using 3-(alk-2-ynyloxy) carbonyl-5-oxazolidine carboxylic acid
FR2986526A1 (fr) 2012-02-03 2013-08-09 Sanofi Sa Procede de preparation de derives du taxol et certains composes intermediaires

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4162251A (en) * 1976-04-05 1979-07-24 Sankyo Company Limited Process for the preparation of β-lactam compounds
USRE34277E (en) * 1988-04-06 1993-06-08 Centre National De La Recherche Scientifique Process for preparing taxol
MX9102128A (es) * 1990-11-23 1992-07-08 Rhone Poulenc Rorer Sa Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene
FR2696460B1 (fr) * 1992-10-05 1994-11-25 Rhone Poulenc Rorer Sa Procédé de préparation de dérivés du taxane.
FR2696458B1 (fr) * 1992-10-05 1994-11-10 Rhone Poulenc Rorer Sa Procédé de préparation de dérivés du taxane.
FR2696459B1 (fr) * 1992-10-05 1994-11-25 Rhone Poulenc Rorer Sa Procédé de préparation de dérivés du taxane.
FR2696464B1 (fr) * 1992-10-05 1994-11-10 Rhone Poulenc Rorer Sa Nouveau procédé d'estérification de la baccatine III et de la désacétyl-10 baccatine III.
KR0131914B1 (ko) * 1992-10-07 1998-04-17 조아퀸 가리데 센트멘나트 오플로옥사진, 레보플로옥사진과 이 유도체의 합성에 이용될 수 있는 벤조옥사진의 수득과정
DE4239445C2 (de) * 1992-11-24 1995-12-14 Hagen Kinsel Vorrichtung zum Beladen von mit Revolvertrommeln ausgerüsteten Waffen
FR2698871B1 (fr) * 1992-12-09 1995-02-24 Rhone Poulenc Rorer Sa Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
FR2702212B1 (fr) * 1993-03-02 1995-04-07 Rhone Poulenc Rorer Sa Nouveaux taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
US5502192A (en) * 1994-08-08 1996-03-26 Ciba-Geigy Corporation Process for the preparation of quinacridones from dihydroquinacridones in an aqueous medium

Also Published As

Publication number Publication date
FR2698360A1 (fr) 1994-05-27
NO304786B1 (no) 1999-02-15
KR950704276A (ko) 1995-11-17
JPH08503485A (ja) 1996-04-16
AU5468894A (en) 1994-06-22
EP0669915B1 (fr) 1997-06-18
ZA938588B (en) 1995-01-18
SK280964B6 (sk) 2000-10-09
RU2114834C1 (ru) 1998-07-10
ES2105596T3 (es) 1997-10-16
FR2698360B1 (fr) 1994-12-30
SK66295A3 (en) 1995-10-11
NO951840L (no) 1995-05-10
NZ257875A (en) 1998-03-25
FI952462A0 (fi) 1995-05-19
HU221164B1 (en) 2002-08-28
WO1994012482A1 (fr) 1994-06-09
TW305839B (es) 1997-05-21
NO951840D0 (no) 1995-05-10
JP3648554B2 (ja) 2005-05-18
PL176659B1 (pl) 1999-07-30
CZ131095A3 (en) 1995-10-18
CA2149637C (fr) 2006-08-29
DK0669915T3 (da) 1997-08-18
DE69311736T2 (de) 1997-11-13
FR2698361B1 (fr) 1995-01-13
AU679195B2 (en) 1997-06-26
FI119289B (fi) 2008-09-30
US5811550A (en) 1998-09-22
SK280965B6 (sk) 2000-10-09
HU9501474D0 (en) 1995-07-28
CZ283525B6 (cs) 1998-04-15
ATE154600T1 (de) 1997-07-15
CA2149637A1 (fr) 1994-06-09
EP0669915A1 (fr) 1995-09-06
RU95113420A (ru) 1997-02-10
DE69311736D1 (de) 1997-07-24
GR3023803T3 (en) 1997-09-30
FR2698361A1 (fr) 1994-05-27
HUT73439A (en) 1996-07-29
PL309567A1 (en) 1995-10-30
KR100330317B1 (ko) 2002-09-27
FI952462A (fi) 1995-05-19
OA10155A (fr) 1996-12-18

Similar Documents

Publication Publication Date Title
ES2095081T3 (es) Procedimiento para la preparacion de derivados de taxano.
DE69307527D1 (de) Verfahren zur herstellung von taxan-derivaten
MX9305768A (es) Nuevos derivados de taxano y procedimiento para su preparacion .
ATE163921T1 (de) Azoxycyanbenzol-derivate
ES2105596T3 (es) Procedimiento para la preparacion de un acido oxazolidina-1,3-carboxilico-5.
FI964002A (fi) Menetelmä 7-hydroksitaksaanien valmistamiseksi
DK0663901T3 (da) Fremgangsmåde til stereoselektiv fremstilling af et derivat af beta-phenylisoserin samt anvendelse deraf til fremstilling af taxanderivater