MX390698B - Antagonistas del receptor 7/8 tipo toll (tlr7/8) y uso de los mismos. - Google Patents

Antagonistas del receptor 7/8 tipo toll (tlr7/8) y uso de los mismos.

Info

Publication number
MX390698B
MX390698B MX2019001096A MX2019001096A MX390698B MX 390698 B MX390698 B MX 390698B MX 2019001096 A MX2019001096 A MX 2019001096A MX 2019001096 A MX2019001096 A MX 2019001096A MX 390698 B MX390698 B MX 390698B
Authority
MX
Mexico
Prior art keywords
tlr7
toll
type
receptor antagonists
antagonists
Prior art date
Application number
MX2019001096A
Other languages
English (en)
Spanish (es)
Other versions
MX2019001096A (es
Inventor
Brian A Sherer
Esther Cleary
Nadia Brugger
Xiaoling Chen
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of MX2019001096A publication Critical patent/MX2019001096A/es
Publication of MX390698B publication Critical patent/MX390698B/es

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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
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    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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    • A61K31/47Quinolines; Isoquinolines
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MX2019001096A 2016-08-08 2017-08-07 Antagonistas del receptor 7/8 tipo toll (tlr7/8) y uso de los mismos. MX390698B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662371917P 2016-08-08 2016-08-08
PCT/US2017/045671 WO2018031434A1 (en) 2016-08-08 2017-08-07 Tlr7/8 antagonists and uses thereof

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MX2019001096A MX2019001096A (es) 2019-07-04
MX390698B true MX390698B (es) 2025-03-11

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