MX376346B - Proceso para preparar trifluoroacetofenonas sustituidas con un grupo de tipo halo. - Google Patents
Proceso para preparar trifluoroacetofenonas sustituidas con un grupo de tipo halo.Info
- Publication number
- MX376346B MX376346B MX2017004787A MX2017004787A MX376346B MX 376346 B MX376346 B MX 376346B MX 2017004787 A MX2017004787 A MX 2017004787A MX 2017004787 A MX2017004787 A MX 2017004787A MX 376346 B MX376346 B MX 376346B
- Authority
- MX
- Mexico
- Prior art keywords
- sub
- trifluoroacetophenones
- halo
- substituted
- preparing
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 3
- 125000001153 fluoro group Chemical group F* 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000006396 nitration reaction Methods 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
- C07C201/06—Preparation of nitro compounds
- C07C201/08—Preparation of nitro compounds by substitution of hydrogen atoms by nitro groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
- C07C201/06—Preparation of nitro compounds
- C07C201/16—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
La invención se refiere a un proceso para preparar un compuesto de fórmula (I) (ver Fórmula) donde R1 es hidrógeno, fluoro o cloro; el proceso comprende: a) hacer reaccionar un compuesto de fórmula (II) (ver Fórmula) donde R1 es hidrógeno, fluoro o cloro; con un agente de nitración para obtener el compuesto de fórmula (III (ver Fórmula) donde R1 es hidrógeno, fluoro o cloro; y b) hacer reaccionar el compuesto de fórmula (III) con cloro gaseoso a una temperatura de 180 °C a 250 °C para obtener el compuesto de fórmula (I).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14188743 | 2014-10-14 | ||
| PCT/EP2015/073119 WO2016058882A1 (en) | 2014-10-14 | 2015-10-07 | Process for the preparation of halo-substituted trifluoroacetophenones |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2017004787A MX2017004787A (es) | 2017-07-26 |
| MX376346B true MX376346B (es) | 2025-03-07 |
Family
ID=51845281
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2017004787A MX376346B (es) | 2014-10-14 | 2015-10-07 | Proceso para preparar trifluoroacetofenonas sustituidas con un grupo de tipo halo. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9862937B2 (es) |
| EP (1) | EP3207024B1 (es) |
| JP (1) | JP6686012B2 (es) |
| KR (1) | KR102436961B1 (es) |
| CN (1) | CN106795080B (es) |
| BR (1) | BR112017007508B1 (es) |
| IL (1) | IL251202B (es) |
| MX (1) | MX376346B (es) |
| TW (1) | TWI670255B (es) |
| WO (1) | WO2016058882A1 (es) |
| ZA (1) | ZA201701973B (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112110806B (zh) * | 2020-09-10 | 2022-11-15 | 浙江永太科技股份有限公司 | 一种1-(3,5-二氯-4-氟-苯基)-2,2,2-三氟乙酮的制备方法及中间体 |
| WO2022061914A1 (zh) * | 2020-09-28 | 2022-03-31 | 台州臻挚生物科技有限公司 | 一种3,5-二卤三氟苯乙酮及其衍生物的制备方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2239217A1 (de) * | 1972-07-13 | 1974-01-24 | Buckman Labor Inc | Substituierte alkylarylketone und verfahren zu ihrer verwendung als herbicide |
| JPH03275646A (ja) * | 1990-03-27 | 1991-12-06 | Asahi Glass Co Ltd | フッ素化安息香酸類の製造方法 |
| ES2443690T3 (es) | 2005-09-02 | 2014-02-20 | Nissan Chemical Industries, Ltd. | Compuesto de benzamida sustituido con isoxazolina y agente controlador de organismos dañinos |
| CN101346336B (zh) * | 2005-12-26 | 2013-02-27 | 日产化学工业株式会社 | 1,3-二(取代苯基)-3-取代-2-丙烯-1-酮化合物和其盐 |
| CN101177379A (zh) | 2006-11-10 | 2008-05-14 | 浙江富盛控股集团有限公司 | 一种2,4,6-三氯氟苯的制备方法 |
| CN101161621B (zh) * | 2007-11-15 | 2010-06-09 | 浙江工业大学 | 一种三氟甲基苯乙酮化合物的制备方法 |
| TWI583664B (zh) * | 2008-04-09 | 2017-05-21 | 杜邦股份有限公司 | 羰基化合物及其製備方法 |
| CN101337862A (zh) | 2008-08-08 | 2009-01-07 | 浙江富盛控股集团有限公司 | 一种2,6-二氯氟苯的制备方法 |
| MX2011011079A (es) * | 2009-04-30 | 2011-11-04 | Basf Se | Procedimiento para preparar compuestos de isoxazolina sustituidos y sus precursores. |
| EP2683713B1 (en) | 2011-03-10 | 2015-04-22 | Novartis Tiergesundheit AG | Isoxazole derivatives |
| WO2012161313A1 (ja) * | 2011-05-26 | 2012-11-29 | 日産化学工業株式会社 | 1-(2-アミノ-置換フェニル)-2-ハロ-2,2-ジフルオロエタノン化合物及び1-(置換フェニル)-2-ハロ-2,2-ジフルオロエタノン化合物の製造方法 |
| CN103664511B (zh) | 2013-12-13 | 2015-07-08 | 浙江林江化工股份有限公司 | 一种3,5-二氯-4-氟溴苯的制备方法 |
-
2015
- 2015-10-07 WO PCT/EP2015/073119 patent/WO2016058882A1/en not_active Ceased
- 2015-10-07 CN CN201580055746.5A patent/CN106795080B/zh active Active
- 2015-10-07 MX MX2017004787A patent/MX376346B/es active IP Right Grant
- 2015-10-07 EP EP15777676.6A patent/EP3207024B1/en active Active
- 2015-10-07 BR BR112017007508-3A patent/BR112017007508B1/pt active IP Right Grant
- 2015-10-07 KR KR1020177009558A patent/KR102436961B1/ko active Active
- 2015-10-07 JP JP2017519644A patent/JP6686012B2/ja active Active
- 2015-10-07 US US15/515,303 patent/US9862937B2/en active Active
- 2015-10-13 TW TW104133496A patent/TWI670255B/zh active
-
2017
- 2017-03-15 IL IL251202A patent/IL251202B/en active IP Right Grant
- 2017-03-22 ZA ZA2017/01973A patent/ZA201701973B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN106795080B (zh) | 2024-06-04 |
| KR102436961B1 (ko) | 2022-08-25 |
| IL251202B (en) | 2019-08-29 |
| US20170218347A1 (en) | 2017-08-03 |
| JP6686012B2 (ja) | 2020-04-22 |
| IL251202A0 (en) | 2017-05-29 |
| EP3207024A1 (en) | 2017-08-23 |
| ZA201701973B (en) | 2018-05-30 |
| TW201623206A (zh) | 2016-07-01 |
| CN106795080A (zh) | 2017-05-31 |
| EP3207024B1 (en) | 2018-07-25 |
| BR112017007508A2 (en) | 2018-06-19 |
| MX2017004787A (es) | 2017-07-26 |
| WO2016058882A1 (en) | 2016-04-21 |
| KR20170070037A (ko) | 2017-06-21 |
| US9862937B2 (en) | 2018-01-09 |
| JP2017530997A (ja) | 2017-10-19 |
| BR112017007508B1 (pt) | 2021-02-02 |
| TWI670255B (zh) | 2019-09-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |