MX375673B - Ensayos basados en interrogatorios celulares y usos de los mismos. - Google Patents
Ensayos basados en interrogatorios celulares y usos de los mismos.Info
- Publication number
- MX375673B MX375673B MX2018002069A MX2018002069A MX375673B MX 375673 B MX375673 B MX 375673B MX 2018002069 A MX2018002069 A MX 2018002069A MX 2018002069 A MX2018002069 A MX 2018002069A MX 375673 B MX375673 B MX 375673B
- Authority
- MX
- Mexico
- Prior art keywords
- interrogations
- cellular
- essays
- essays based
- cancer
- Prior art date
Links
Classifications
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/025—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Urology & Nephrology (AREA)
- Analytical Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Evolutionary Biology (AREA)
- Theoretical Computer Science (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Medical Informatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Diabetes (AREA)
Abstract
La presente invención se refiere a un descubrimiento de Tecnología de plataforma para analizar un sistema biológico o proceso (por ejemplo, una condición de enfermedad, tal como cáncer) mediante la construcción de un modelo.
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261619326P | 2012-04-02 | 2012-04-02 | |
| US201261620305P | 2012-04-04 | 2012-04-04 | |
| US201261665631P | 2012-06-28 | 2012-06-28 | |
| US201261668617P | 2012-07-06 | 2012-07-06 | |
| US201261678596P | 2012-08-01 | 2012-08-01 | |
| US201261678590P | 2012-08-01 | 2012-08-01 | |
| PCT/US2012/054321 WO2013151577A1 (en) | 2012-04-02 | 2012-09-07 | Interrogatory cell-based assays and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX375673B true MX375673B (es) | 2025-03-06 |
Family
ID=49235335
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014011797A MX357392B (es) | 2012-04-02 | 2012-09-07 | Ensayos basados en interrogatorios celulares y uso de los mismos. |
| MX2018002069A MX375673B (es) | 2012-04-02 | 2012-09-07 | Ensayos basados en interrogatorios celulares y usos de los mismos. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014011797A MX357392B (es) | 2012-04-02 | 2012-09-07 | Ensayos basados en interrogatorios celulares y uso de los mismos. |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US10061887B2 (es) |
| EP (1) | EP2834366B1 (es) |
| JP (3) | JP6189926B2 (es) |
| KR (2) | KR20200105524A (es) |
| CN (3) | CN110456035A (es) |
| AU (2) | AU2012376214B2 (es) |
| BR (1) | BR112014024537A2 (es) |
| CA (1) | CA2869296A1 (es) |
| EA (1) | EA038600B1 (es) |
| HK (1) | HK1209161A1 (es) |
| IL (1) | IL234920B (es) |
| MX (2) | MX357392B (es) |
| SG (2) | SG10201608234UA (es) |
| WO (1) | WO2013151577A1 (es) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112013022208A2 (pt) | 2011-03-02 | 2022-03-08 | Berg Llc | Ensaios baseados em investigação celular e usos destes |
| US10061887B2 (en) | 2012-04-02 | 2018-08-28 | Berg Llc | Interrogatory cell-based assays and uses thereof |
| EP2668945A1 (de) | 2012-06-01 | 2013-12-04 | Bayer Technology Services GmbH | Genotyp- bzw. Phänotyp-basierte Arzeimittelformulierungen |
| US9449284B2 (en) * | 2012-10-04 | 2016-09-20 | Nec Corporation | Methods and systems for dependency network analysis using a multitask learning graphical lasso objective function |
| CN103558354B (zh) | 2013-11-15 | 2015-07-15 | 南京大学 | 一种基于生物组学整合技术的水体毒性分析方法 |
| EP3158487A1 (en) * | 2014-06-20 | 2017-04-26 | Connecticut Children's Medical Center | Automated cell culture system and corresponding methods |
| CN114203296B (zh) | 2014-09-11 | 2025-10-17 | 布普格生物制药公司 | 基于患者数据的用于健康护理诊断和治疗的贝叶斯因果关系网络模型 |
| CN105624275B (zh) * | 2014-11-06 | 2020-03-27 | 上海市东方医院 | Eif4g1在鳞癌诊断和治疗中的应用 |
| JP6270221B2 (ja) * | 2015-02-13 | 2018-01-31 | 国立研究開発法人産業技術総合研究所 | バイオマーカー探索方法、バイオマーカー探索装置、及びプログラム |
| KR101786859B1 (ko) * | 2015-04-30 | 2017-10-17 | 서울대학교산학협력단 | 혈장 내 아밀로이드베타의 농도를 통해 알츠하이머병을 임상학적 및 병리학적으로 모니터링하는 방법 |
| US10395759B2 (en) | 2015-05-18 | 2019-08-27 | Regeneron Pharmaceuticals, Inc. | Methods and systems for copy number variant detection |
| CN107922936B (zh) * | 2015-05-28 | 2021-10-22 | 施特丁.奈德兰卡克研究所-安东尼.范.列文虎克医院 | 识别影响表型的遗传元件的分析 |
| CN106250717B (zh) * | 2015-06-04 | 2019-03-12 | 徐勇 | 急性髓性白血病的miRNA与转录因子的系统及其构建方法和应用 |
| US20160363567A1 (en) * | 2015-06-15 | 2016-12-15 | Lunatech, Llc | Vapor Device For Stressing And Analyzing Compounds |
| WO2017065127A1 (ja) * | 2015-10-14 | 2017-04-20 | 公立大学法人横浜市立大学 | 腎癌薬物療法の効果判定のための血中バイオマーカー |
| SG11201806812SA (en) | 2016-02-12 | 2018-09-27 | Regeneron Pharma | Methods and systems for detection of abnormal karyotypes |
| ES3024557T3 (en) * | 2016-06-10 | 2025-06-04 | Univ California | Image-based cell sorting systems and methods |
| EP3538095A4 (en) | 2016-11-14 | 2020-06-17 | Berg LLC | Methods for treating parkinson's disease |
| CN106834105A (zh) * | 2017-02-21 | 2017-06-13 | 齐齐哈尔医学院 | 一种用于表观遗传分析的设备和方法 |
| US11636917B2 (en) * | 2017-06-28 | 2023-04-25 | The Regents Of The University Of California | Simulating the metabolic pathway dynamics of an organism |
| CN107475346B (zh) * | 2017-08-11 | 2021-08-06 | 北京汉典制药有限公司 | 一种体外筛选糖尿病肾病药物的方法 |
| JP6902977B2 (ja) * | 2017-09-22 | 2021-07-14 | 新日本無線株式会社 | 起動回路の故障検出方法 |
| EP3697925A4 (en) * | 2017-10-18 | 2021-06-23 | Venn Biosciences Corporation | IDENTIFICATION AND USE OF BIOLOGICAL PARAMETERS FOR DIAGNOSIS AND THERAPY MONITORING |
| JP2021073432A (ja) * | 2018-03-02 | 2021-05-13 | 国立研究開発法人医薬基盤・健康・栄養研究所 | 治療標的である活性化キナーゼのスクリーニング方法 |
| JP7176381B2 (ja) * | 2018-12-03 | 2022-11-22 | 富士通株式会社 | 環状分子の構造探索方法、及び構造探索装置、並びにプログラム |
| CN109536473A (zh) * | 2018-12-19 | 2019-03-29 | 华中科技大学鄂州工业技术研究院 | 整合多组学数据推测细胞转分化中关键蛋白质激酶的方法 |
| EP3935581A4 (en) | 2019-03-04 | 2022-11-30 | Iocurrents, Inc. | DATA COMPRESSION AND COMMUNICATION USING MACHINE LEARNING |
| US20210080466A1 (en) * | 2019-06-26 | 2021-03-18 | Berg Llc | Markers for the diagnosis of prostate cancer |
| AU2021236148A1 (en) * | 2020-03-10 | 2022-10-13 | AI:ON Innovations, Inc. | System and methods for mammalian transfer learning |
| WO2021251331A1 (ja) * | 2020-06-08 | 2021-12-16 | 国立大学法人 東京医科歯科大学 | 標的分子予測方法 |
| JP7735624B2 (ja) * | 2020-08-31 | 2025-09-09 | 武田薬品工業株式会社 | 推論装置、推論方法、推論プログラム、モデル生成方法、推論サービス提供システム、推論サービス提供方法及び推論サービス提供プログラム |
| US11227690B1 (en) * | 2020-09-14 | 2022-01-18 | Opendna Ltd. | Machine learning prediction of therapy response |
| CN113035298B (zh) * | 2021-04-02 | 2023-06-20 | 南京信息工程大学 | 递归生成大阶数行限制覆盖阵列的药物临床试验设计方法 |
| CN113138249B (zh) * | 2021-04-12 | 2021-11-23 | 北京蛋白质组研究中心 | 基于微孔阵列芯片的微量样本代谢组、蛋白质组和磷酸化蛋白质组多组学分析方法 |
| EP4338163A4 (en) * | 2021-05-13 | 2024-11-06 | Scipher Medicine Corporation | ASSESSMENT OF RESPONSE TO THERAPY |
| CN113943720B (zh) * | 2021-11-03 | 2025-09-16 | 江苏省农业科学院 | 一种绿盲蝽GRK基因、其dsRNA及其合成方法和应用 |
| WO2023230268A1 (en) * | 2022-05-27 | 2023-11-30 | Memorial Sloan-Kettering Cancer Center | Systems and methods for metabolite imputation |
| CN117417914A (zh) * | 2022-07-18 | 2024-01-19 | 华东师范大学 | 预防和保护脑缺血疾病的标志物及阿司匹林衍生物在预防和保护脑缺血疾病中的应用 |
| WO2024081570A1 (en) * | 2022-10-10 | 2024-04-18 | Eli Lilly And Company | Methods and systems for using causal networks to develop models for evaluating biological processes |
| JP2025536258A (ja) * | 2022-10-13 | 2025-11-05 | ソマロジック オペレーティング カンパニー インコーポレイテッド | プロテオミクスモデルの検証のためのシステムおよび方法 |
| WO2024211805A1 (en) * | 2023-04-07 | 2024-10-10 | The Medical College Of Wisconsin, Inc. | Compositions and methods for treatment or preventative treatment of cancer including triple negative breast cancer and/or lung cancer |
| CN117133375B (zh) * | 2023-07-24 | 2025-05-30 | 浙江大学 | 一种基于机器学习的致肥胖化学品预测方法及装置 |
| KR102763225B1 (ko) * | 2023-09-26 | 2025-02-07 | 주식회사 그래디언트바이오컨버전스 | 최적의 오가노이드 배양배지 조합 결정 장치, 배양배지 조합들에 대한 생존율을 산출하여 최적의 조합을 결정하는 방법, 및 컴퓨터 프로그램 |
| KR102763227B1 (ko) * | 2023-09-26 | 2025-02-07 | 주식회사 그래디언트바이오컨버전스 | 최적의 줄기 세포 배양배지 조합 결정 장치, 배양배지 조합들에 대한 분화 성공률을 산출하여 최적의 조합을 결정하는 방법, 및 컴퓨터 프로그램 |
| CN120405134A (zh) * | 2024-01-30 | 2025-08-01 | 抟相医药(杭州)有限公司 | 基于凝聚体荧光漂白恢复技术(Drop-FRAP)的生物大分子相互作用调节剂筛选平台 |
| CN118607082A (zh) * | 2024-08-09 | 2024-09-06 | 成都理工大学 | 一种基于深度学习的压裂过程中套管变形的预测方法 |
| CN119120480B (zh) * | 2024-10-17 | 2025-04-29 | 山东省农业科学院畜牧兽医研究所 | 一种用于华西牛育种调节的环状rna及其应用 |
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