MX373957B - Un método in vitro para detectar un biomarcador de cáncer en un sujeto. - Google Patents

Un método in vitro para detectar un biomarcador de cáncer en un sujeto.

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Publication number
MX373957B
MX373957B MX2015013141A MX2015013141A MX373957B MX 373957 B MX373957 B MX 373957B MX 2015013141 A MX2015013141 A MX 2015013141A MX 2015013141 A MX2015013141 A MX 2015013141A MX 373957 B MX373957 B MX 373957B
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Mexico
Prior art keywords
subject
detecting
vitro method
cancer biomarker
exosomes
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MX2015013141A
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English (en)
Other versions
MX2015013141A (es
Inventor
Raghu Kalluri
Sonia Melo
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Univ Texas
Beth Israel Deaconess Medical Ct Inc
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Publication date
Application filed by Univ Texas, Beth Israel Deaconess Medical Ct Inc filed Critical Univ Texas
Publication of MX2015013141A publication Critical patent/MX2015013141A/es
Publication of MX373957B publication Critical patent/MX373957B/es

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Abstract

La presente invención se refiere a un método in vitro para detectar un biomarcador de cáncer en un sujeto, caracterizado porque comprende: (a) medir en una muestra biológica del suejto el nivel de: (i) dicer enuna fracción de exosoma de la muestra; y/o (ii) la actividad de procesamiento de miARN precursor de Dicer en una Fracción de exosoma de la muestra; y (b) identificar el sujeto que tiene o no tiene un biomarcador de cáncer con base en el nivel medido de Dicer o actividad de procesameinto de Dicer. Mediante la determinación del contenido de miARN de exosomas en una muestra de un sujeto o mediante la detección del procesamiento de miARN en exosomas.
MX2015013141A 2013-03-15 2014-03-14 Un método in vitro para detectar un biomarcador de cáncer en un sujeto. MX373957B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361791301P 2013-03-15 2013-03-15
PCT/US2014/027541 WO2014152622A1 (en) 2013-03-15 2014-03-14 Mirna biogenesis in exosomes for diagnosis and therapy

Publications (2)

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MX2015013141A MX2015013141A (es) 2016-06-21
MX373957B true MX373957B (es) 2020-07-13

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MX2015013141A MX373957B (es) 2013-03-15 2014-03-14 Un método in vitro para detectar un biomarcador de cáncer en un sujeto.
MX2020005165A MX2020005165A (es) 2013-03-15 2015-09-15 Biogenesis de miarn en exosomas para diagnostico y terapia.

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US (2) US20160024503A1 (es)
EP (2) EP3527670B1 (es)
JP (2) JP6554458B2 (es)
KR (1) KR102183406B1 (es)
CN (2) CN109852695B (es)
AU (2) AU2014239309B2 (es)
BR (1) BR112015023275B1 (es)
CA (2) CA3209023A1 (es)
ES (1) ES2966571T3 (es)
HK (1) HK1218143A1 (es)
IL (2) IL241409B (es)
MX (2) MX373957B (es)
PT (1) PT3527670T (es)
RU (2) RU2644247C2 (es)
WO (1) WO2014152622A1 (es)

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CN109852695A (zh) 2019-06-07
IL241409A0 (en) 2015-11-30
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AU2014239309B2 (en) 2020-03-05
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