MX373164B - Composiciones antimicrobianas de poliamida y tratamiento de mastitis. - Google Patents

Composiciones antimicrobianas de poliamida y tratamiento de mastitis.

Info

Publication number
MX373164B
MX373164B MX2015013262A MX2015013262A MX373164B MX 373164 B MX373164 B MX 373164B MX 2015013262 A MX2015013262 A MX 2015013262A MX 2015013262 A MX2015013262 A MX 2015013262A MX 373164 B MX373164 B MX 373164B
Authority
MX
Mexico
Prior art keywords
polyamide compositions
mastitis
mastitis treatment
antimicrobial polyamide
treatment
Prior art date
Application number
MX2015013262A
Other languages
English (en)
Spanish (es)
Other versions
MX2015013262A (es
Inventor
Izabela Galeska
Pradeep K Dhal
Susan Mancini Cady
Original Assignee
Genzyme Corp
Boehringer Ingelheim Animal Health Usa Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp, Boehringer Ingelheim Animal Health Usa Inc filed Critical Genzyme Corp
Publication of MX2015013262A publication Critical patent/MX2015013262A/es
Publication of MX373164B publication Critical patent/MX373164B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
    • C08G69/26—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from polyamines and polycarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A61K31/787—Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/16—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with acylated ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/66—Polyesters containing oxygen in the form of ether groups
    • C08G63/668—Polyesters containing oxygen in the form of ether groups derived from polycarboxylic acids and polyhydroxy compounds
    • C08G63/672—Dicarboxylic acids and dihydroxy compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02—Polyamines
    • C08G73/0273—Polyamines containing heterocyclic moieties in the main chain
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02—Polyamines
    • C08G73/028—Polyamidoamines
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/06—Polycondensates having nitrogen-containing heterocyclic rings in the main chain of the macromolecule
    • C08G73/0622—Polycondensates containing six-membered rings, not condensed with other rings, with nitrogen atoms as the only ring hetero atoms
    • C08G73/0627—Polycondensates containing six-membered rings, not condensed with other rings, with nitrogen atoms as the only ring hetero atoms with only one nitrogen atom in the ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Polyamides (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cephalosporin Compounds (AREA)
MX2015013262A 2013-03-15 2014-03-11 Composiciones antimicrobianas de poliamida y tratamiento de mastitis. MX373164B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361790231P 2013-03-15 2013-03-15
PCT/US2014/023299 WO2014150451A1 (en) 2013-03-15 2014-03-11 Antimicrobial polyamide compositions and mastitis treatment

Publications (2)

Publication Number Publication Date
MX2015013262A MX2015013262A (es) 2016-04-04
MX373164B true MX373164B (es) 2020-05-07

Family

ID=50390295

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2015013262A MX373164B (es) 2013-03-15 2014-03-11 Composiciones antimicrobianas de poliamida y tratamiento de mastitis.
MX2015012119A MX364611B (es) 2013-03-15 2014-03-11 Poliamidas con funcionalidad amina.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2015012119A MX364611B (es) 2013-03-15 2014-03-11 Poliamidas con funcionalidad amina.

Country Status (22)

Country Link
US (3) US10131744B2 (enExample)
EP (2) EP2970586B1 (enExample)
JP (4) JP7000021B2 (enExample)
KR (2) KR102233537B1 (enExample)
CN (2) CN105338976B (enExample)
AR (1) AR095366A1 (enExample)
AU (2) AU2014237232B9 (enExample)
BR (1) BR112015022224A2 (enExample)
CA (2) CA2907045C (enExample)
CL (1) CL2015002762A1 (enExample)
EA (1) EA030750B1 (enExample)
ES (1) ES2835382T3 (enExample)
HK (1) HK1220711A1 (enExample)
IL (1) IL241405A0 (enExample)
MX (2) MX373164B (enExample)
NZ (1) NZ712876A (enExample)
RU (1) RU2644554C2 (enExample)
SG (1) SG11201506359UA (enExample)
TW (2) TWI624263B (enExample)
UA (1) UA119642C2 (enExample)
WO (2) WO2014150338A1 (enExample)
ZA (1) ZA201506808B (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2970586B1 (en) 2013-03-15 2022-12-07 Genzyme Corporation Amine functional polyamides
MX2017000447A (es) * 2014-07-11 2017-04-27 Genzyme Corp Poliaminas de cadena principal.
CN104292148A (zh) * 2014-09-22 2015-01-21 西南科技大学 一种橡胶或树脂光稳定剂的制备方法
CN107735426A (zh) * 2015-07-09 2018-02-23 汉高知识产权控股有限责任公司 低粘度透明聚酰胺
CA3002214C (en) * 2015-11-03 2022-01-04 Zoetis Services Llc Sol-gel polymer composites and uses thereof
CA3020634C (en) * 2016-04-14 2025-06-17 Genzyme Corporation MULTIDOSE COMPOSITIONS CONTAINING AN ANTIMICROBIAL PRESERVATIVE BASED ON POLYAMIDE OR OCTENIDINE
KR20190018317A (ko) * 2017-08-14 2019-02-22 한국생명공학연구원 모노아세틸디아실글리세롤 화합물을 함유하는 슈도모나스 속 미생물 감염증의 예방 또는 치료용 조성물
US10836864B2 (en) 2017-12-12 2020-11-17 International Business Machines Corporation Chemical compositions with antimicrobial functionality
US10743537B2 (en) 2017-12-12 2020-08-18 International Business Machines Corporation Monomer compositions with antimicrobial functionality
US10687530B2 (en) 2017-12-12 2020-06-23 International Business Machines Corporation Hydrophilic polymers with antimicrobial functionalities
US10667514B2 (en) 2017-12-12 2020-06-02 International Business Machines Corporation Antimicrobial ionene compositions with a variety of functional groups
US10653142B2 (en) 2017-12-12 2020-05-19 International Business Machines Corporation Polymers with antimicrobial functionalities
US10595527B2 (en) 2017-12-12 2020-03-24 International Business Machines Corporation Antimicrobial polymers capable of supramolecular assembly
US10687528B2 (en) 2017-12-12 2020-06-23 International Business Machines Corporation Antimicrobial polymers with enhanced functionalities
RU2732206C2 (ru) * 2018-12-29 2020-09-14 Вероника Андреевна Гусева Способ лечения маститов у крупного рогатого скота
KR102052086B1 (ko) * 2019-07-25 2019-12-04 복세원 젖소 유두 보호제 및 그 제조방법
CN111471630B (zh) * 2020-06-11 2021-11-02 鲁东大学 一株棒杆菌Ytld-phe09及其应用
CN114796583B (zh) * 2022-03-25 2023-02-10 浙江大学 一种基于聚硫辛酸的生物医用贴片材料及其制备方法
CN115531518B (zh) * 2022-09-22 2023-05-23 湖南科技学院 一种用于防治奶牛乳房炎的中药软膏及其制备方法

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3583946A (en) * 1969-04-24 1971-06-08 Monsanto Co Polyureas derived from dipiperidines
IT981412B (it) * 1973-03-15 1974-10-10 Montedison Spa Poliammidi da acidi eterociclici aromatici ortocarbossilici e pro cedimento per prepararle
US4070400A (en) * 1975-10-16 1978-01-24 Merck & Co., Inc. Diphenyl polyamides having a cyclohexylene moiety
DE2942680C2 (de) * 1979-10-23 1986-02-27 Schering AG, 1000 Berlin und 4709 Bergkamen Schmelzkleber auf Basis von Polyesteramiden und deren Verwendung zum Verkleben von organischen und anorganischen Substraten
JPS591531A (ja) * 1982-06-25 1984-01-06 Daicel Chem Ind Ltd 感温性高分子材料
JPS596220A (ja) * 1982-07-01 1984-01-13 Daicel Chem Ind Ltd 新規ポリアミド共重合体
US4462942A (en) * 1982-07-30 1984-07-31 Eli Lilly And Company A47934 Antibiotic and process for production thereof
JPH01252633A (ja) * 1987-12-03 1989-10-09 Ricoh Co Ltd ポリアミドを用いた熱転写記録媒体及び新規なポリアミド
JPH0228208A (ja) * 1988-04-28 1990-01-30 Japan Synthetic Rubber Co Ltd 感放射線性共重合体およびその製造方法
JPH03258832A (ja) * 1990-03-08 1991-11-19 Mitsubishi Kasei Corp 不飽和ポリアミド
US6369049B1 (en) * 1998-04-30 2002-04-09 Eli Lilly And Company Treatment of mastitis
US6203812B1 (en) * 1998-06-29 2001-03-20 Hydromer, Inc. Hydrophilic polymer blends used to prevent cow skin infections
AUPP584298A0 (en) * 1998-09-14 1998-10-08 Starpharma Limited Antimicrobial and antiparasitic agents
US20020009491A1 (en) * 2000-02-14 2002-01-24 Rothbard Jonathan B. Compositions and methods for enhancing drug delivery across biological membranes and tissues
PT1395289E (pt) * 2000-06-08 2011-03-16 Sang Dr Christine Tratamento da dor neuropática com antagonistas do receptor de n-metil-d-aspartato (nmda)
CA2411925C (en) * 2000-06-12 2011-08-16 University Of Saskatchewan Immunization of dairy cattle with mig protein
US6998115B2 (en) * 2000-10-10 2006-02-14 Massachusetts Institute Of Technology Biodegradable poly(β-amino esters) and uses thereof
GB0029004D0 (en) * 2000-11-28 2001-01-10 Pharmacia & Upjohn Spa Process for preparing distamycin derivatives
US20040013698A1 (en) * 2001-07-09 2004-01-22 Aust Duncan T Method for preparing topical preparations containing skin protective agents with enhanced barrier properties
AU2003291087A1 (en) * 2002-11-19 2004-06-15 Genzyme Corporation Ionene oligomers and polymers
DE102004054873A1 (de) * 2004-11-12 2006-05-18 Bayer Healthcare Ag Behandlung von Mastitis
WO2009111838A1 (en) * 2008-03-13 2009-09-17 Agriculture Victoria Services Pty Limited Method of treatment using antimicrobial composition
EP2138171A1 (en) * 2008-06-18 2009-12-30 Istituto Superiore Di Sanita' Veterinarian compositions containing terpinen-4-ol for the treatment and prevention of mastitis
JP5599808B2 (ja) * 2008-11-07 2014-10-01 ノバベイ・ファーマシューティカルズ・インコーポレイテッド 抗菌性ｎ−塩素化組成物
JP5808082B2 (ja) * 2010-04-30 2015-11-10 株式会社Adeka 細胞への水溶性高分子量物質の導入方法及び導入剤
US8758778B2 (en) 2010-09-16 2014-06-24 The Regents Of The University Of California Polymeric nano-carriers with a linear dual response mechanism and uses thereof
CN102653779B (zh) 2011-03-04 2014-02-19 北京科润三联生物技术有限责任公司 一种新型重组抗菌多肽药物的制备方法
WO2012151555A1 (en) 2011-05-04 2012-11-08 President And Fellows Of Harvard College Methods and coatings for treating biofilms
DK2709619T3 (en) * 2011-05-16 2018-01-15 Cellceutix Corp RELATIONSHIPS FOR USING THE TREATMENT OF MUCOSITIS
AU2013283375B2 (en) 2012-06-29 2018-04-26 Elanco Animal Health Gmbh Pharmaceutical compositions and treatment of mastitis
EP2970586B1 (en) 2013-03-15 2022-12-07 Genzyme Corporation Amine functional polyamides

Also Published As

Publication number Publication date
KR102233537B1 (ko) 2021-03-29
NZ712876A (en) 2016-09-30
EP2970586B1 (en) 2022-12-07
AU2014237232B9 (en) 2018-02-01
EP2970586A1 (en) 2016-01-20
AU2014237169B2 (en) 2017-02-16
SG11201506359UA (en) 2015-09-29
CA2906334A1 (en) 2014-09-25
JP6359630B2 (ja) 2018-07-18
MX2015012119A (es) 2016-05-18
HK1220711A1 (zh) 2017-05-12
AU2014237232B2 (en) 2018-01-18
AU2014237169A1 (en) 2015-10-29
AR095366A1 (es) 2015-10-14
HK1215537A1 (zh) 2016-09-02
JP2020045493A (ja) 2020-03-26
CA2907045A1 (en) 2014-09-25
JP2016516700A (ja) 2016-06-09
RU2015144224A (ru) 2017-04-21
EP2968231A1 (en) 2016-01-20
JP2016514192A (ja) 2016-05-19
US20140275469A1 (en) 2014-09-18
EA201591812A1 (ru) 2016-02-29
TWI667028B (zh) 2019-08-01
US10131744B2 (en) 2018-11-20
JP2018188662A (ja) 2018-11-29
CN105338976B (zh) 2018-12-04
BR112015022224A2 (pt) 2017-07-18
ZA201506808B (en) 2017-11-29
CA2906334C (en) 2023-03-14
CA2907045C (en) 2020-12-08
BR112015023445A2 (enExample) 2017-08-29
MX2015013262A (es) 2016-04-04
BR112015023445A8 (pt) 2022-06-28
KR20150131354A (ko) 2015-11-24
US10113032B2 (en) 2018-10-30
IL241405A0 (en) 2015-11-30
CN105189607B (zh) 2018-06-15
UA119642C2 (uk) 2019-07-25
US20160208046A1 (en) 2016-07-21
EA030750B1 (ru) 2018-09-28
CL2015002762A1 (es) 2016-04-08
TWI624263B (zh) 2018-05-21
US20140271526A1 (en) 2014-09-18
WO2014150338A1 (en) 2014-09-25
TW201513872A (zh) 2015-04-16
US9326994B2 (en) 2016-05-03
ES2835382T3 (es) 2021-06-22
KR20150132325A (ko) 2015-11-25
TW201513873A (zh) 2015-04-16
CN105338976A (zh) 2016-02-17
JP7000021B2 (ja) 2022-01-19
AU2014237232A1 (en) 2015-10-22
CN105189607A (zh) 2015-12-23
EP2968231B1 (en) 2020-07-01
WO2014150451A1 (en) 2014-09-25
MX364611B (es) 2019-05-02
RU2644554C2 (ru) 2018-02-13

Similar Documents

Publication Publication Date Title
NZ712876A (en) Antimicrobial polyamide compositions and mastitis treatment
PH12016500511A1 (en) Selective grp94 inhibitors and uses thereof
MX388720B (es) Composiciones a base de nanoparticulas.
EA201591137A1 (ru) Ингибиторы mk2 и их применения
BR112016008623A2 (pt) aditivo, composição e métodos de processamento de polímero.
BR112014021104A2 (pt) métodos e composições para o tratamento da doença de huntington
MX372990B (es) Composiciones para el tratamiento del ojo seco.
BR112015029686A2 (pt) composições para o tratamento de superfícies compreendendo corantes fotocrômicos
EP3380062A4 (en) Compositions for treating the hair
DK3055360T3 (da) Behandlede fyldstoffer, sammensætninger dermed og deraf fremstillede artikler
ZA201500649B (en) Pharmaceutical compositions and treatment of mastitis
PH12016500453A1 (en) Antimicrobial compounds and methods of making and using the same
EP2983695A4 (en) PROCESSES, USES AND COMPOSITIONS OF TIE2 AGONISTS
ECSP14011792A (es) Inhibidores de iap
EP2977388A4 (en) COPOLYMER RUBBER WITH NITRILE GROUP, NETWORKABLE RUBBER COMPOSITION AND RUBBER-LINKED PRODUCT
MX378754B (es) Métodos y reactivos para la prevención y/o el tratamiento de infecciones.
EA201692289A1 (ru) Замещенные [1,2,4]триазольные и имидазольные соединения в качестве фунгицидов
MX2018004881A (es) Aditivo para tratamiento posterior interno de composiciones aglutinantes minerales.
EP3311659C0 (en) ANIMAL LITTER COMPOSITION, PARTICULARLY SUITABLE FOR CATS
BR112014032290A2 (pt) composições e métodos para tratar ou prevenir infecção de pneumovírus e doenças associadas.
BR112017000258A2 (pt) poliaminas de cadeia principal
MX2016003529A (es) Quimicos agricolas.
PH12016501448B1 (en) Antifungal composition
FR3018996B1 (fr) Dispositif d'arrosage de jeunes plants, notamment de plants de vigne
HUE048864T2 (hu) Lizobaktin szarvasmarhafélék tõgygyulladásának kezelésében történõ alkalmazásra

Legal Events

Date Code Title Description
GB Transfer or rights

Owner name: GENZYME CORPORATION

FG Grant or registration