MX369671B - Formulaciones con oxidacion reducida. - Google Patents

Formulaciones con oxidacion reducida.

Info

Publication number
MX369671B
MX369671B MX2015011432A MX2015011432A MX369671B MX 369671 B MX369671 B MX 369671B MX 2015011432 A MX2015011432 A MX 2015011432A MX 2015011432 A MX2015011432 A MX 2015011432A MX 369671 B MX369671 B MX 369671B
Authority
MX
Mexico
Prior art keywords
formulations
protein
methods
oxidation
reduced oxidation
Prior art date
Application number
MX2015011432A
Other languages
English (en)
Other versions
MX2015011432A (es
Inventor
Sreedhara Alavattam
Mary Mallaney
Parbir Grewal
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of MX2015011432A publication Critical patent/MX2015011432A/es
Publication of MX369671B publication Critical patent/MX369671B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591—Stabilisation, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Organic Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Lubricants (AREA)

Abstract

La presente invención se refiere a formulaciones que comprenden una proteína en combinación con un compuesto que impide la oxidación de la proteína. La invención también proporciona métodos para elaborar estas formulaciones y métodos para usar estas formulaciones. La invención proporciona además métodos para examinar compuestos para impedir la oxidación de una proteína en una composición de proteína y métodos para prevenir la oxidación de una proteína en una formulación.
MX2015011432A 2013-03-13 2014-03-13 Formulaciones con oxidacion reducida. MX369671B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361780845P 2013-03-13 2013-03-13
US201361909813P 2013-11-27 2013-11-27
PCT/US2014/026841 WO2014160495A1 (en) 2013-03-13 2014-03-13 Formulations with reduced oxidation

Publications (2)

Publication Number Publication Date
MX2015011432A MX2015011432A (es) 2016-04-27
MX369671B true MX369671B (es) 2019-11-15

Family

ID=51625442

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2015011432A MX369671B (es) 2013-03-13 2014-03-13 Formulaciones con oxidacion reducida.
MX2019013560A MX2019013560A (es) 2013-03-13 2015-09-02 Formulaciones con oxidacion reducida.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2019013560A MX2019013560A (es) 2013-03-13 2015-09-02 Formulaciones con oxidacion reducida.

Country Status (25)

Country Link
EP (1) EP2968466B1 (es)
JP (3) JP6389236B2 (es)
KR (1) KR102237885B1 (es)
CN (2) CN110075293A (es)
AU (3) AU2014243700B2 (es)
BR (1) BR112015022484A2 (es)
CA (2) CA2904166C (es)
DK (1) DK2968466T3 (es)
ES (1) ES2688895T3 (es)
HK (1) HK1211219A1 (es)
HR (1) HRP20181504T1 (es)
HU (1) HUE039948T2 (es)
IL (2) IL269947B (es)
LT (1) LT2968466T (es)
MX (2) MX369671B (es)
MY (1) MY174679A (es)
NZ (1) NZ711566A (es)
PL (1) PL2968466T3 (es)
PT (1) PT2968466T (es)
RS (1) RS57813B1 (es)
RU (1) RU2707092C2 (es)
SG (2) SG10201705525VA (es)
SI (1) SI2968466T1 (es)
WO (1) WO2014160495A1 (es)
ZA (2) ZA201506876B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112015022475A8 (pt) * 2013-03-13 2019-11-26 Genentech Inc formulação líquida e método para impedir a oxidação de uma proteína em uma formulação de proteína
US10653779B2 (en) 2013-03-13 2020-05-19 Genentech, Inc. Formulations with reduced oxidation
US20140314778A1 (en) 2013-03-13 2014-10-23 Genentech, Inc. Formulations with reduced oxidation
DK3475303T3 (da) 2016-06-27 2021-05-31 Morphosys Ag Anti-cd19-antistofformuleringer
WO2019073996A1 (ja) * 2017-10-13 2019-04-18 株式会社タムラテコ 有害物処理方法およびオゾン発生装置
CA3106537A1 (en) 2018-08-08 2020-02-13 Genentech, Inc. Use of tryptophan derivatives and l-methionine for protein formulation

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Also Published As

Publication number Publication date
HRP20181504T1 (hr) 2018-11-02
SI2968466T1 (sl) 2018-10-30
MY174679A (en) 2020-05-06
IL269947B (en) 2022-08-01
CN104968362A (zh) 2015-10-07
HK1211219A1 (en) 2016-05-20
RU2015143548A (ru) 2017-04-20
CN104968362B (zh) 2018-12-14
SG11201507043SA (en) 2015-10-29
EP2968466A1 (en) 2016-01-20
EP2968466B1 (en) 2018-07-25
EP2968466A4 (en) 2016-10-26
IL269947A (es) 2019-12-31
JP2018150317A (ja) 2018-09-27
NZ711566A (en) 2020-06-26
LT2968466T (lt) 2018-10-10
RS57813B1 (sr) 2018-12-31
JP6389236B2 (ja) 2018-09-12
MX2015011432A (es) 2016-04-27
DK2968466T3 (en) 2018-10-22
AU2014243700A1 (en) 2015-10-08
ES2688895T3 (es) 2018-11-07
AU2019202464B2 (en) 2020-12-10
CA3113172A1 (en) 2014-10-02
CA2904166A1 (en) 2014-10-02
AU2014243700B2 (en) 2019-01-24
CA2904166C (en) 2021-05-18
PT2968466T (pt) 2018-10-22
KR20150130397A (ko) 2015-11-23
ZA201906057B (en) 2022-04-28
JP2016520521A (ja) 2016-07-14
IL240933B (en) 2019-10-31
BR112015022484A2 (pt) 2017-07-18
WO2014160495A1 (en) 2014-10-02
IL240933A0 (en) 2015-11-30
NZ751543A (en) 2020-09-25
AU2021201366A1 (en) 2021-03-18
MX2019013560A (es) 2020-01-20
ZA201506876B (en) 2019-12-18
HUE039948T2 (hu) 2019-02-28
KR102237885B1 (ko) 2021-04-07
SG10201705525VA (en) 2017-08-30
CN110075293A (zh) 2019-08-02
RU2707092C2 (ru) 2019-11-22
AU2019202464A1 (en) 2019-05-02
PL2968466T3 (pl) 2018-11-30
JP2020164531A (ja) 2020-10-08

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