MX362854B - Siarn y su uso en los metodos y composiciones para el tratamiento y/o prevencion de enfermedades de los ojos. - Google Patents
Siarn y su uso en los metodos y composiciones para el tratamiento y/o prevencion de enfermedades de los ojos.Info
- Publication number
- MX362854B MX362854B MX2015002802A MX2015002802A MX362854B MX 362854 B MX362854 B MX 362854B MX 2015002802 A MX2015002802 A MX 2015002802A MX 2015002802 A MX2015002802 A MX 2015002802A MX 362854 B MX362854 B MX 362854B
- Authority
- MX
- Mexico
- Prior art keywords
- prevention
- compositions
- treatment
- methods
- sirna
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 title abstract 2
- 108020004459 Small interfering RNA Proteins 0.000 title 1
- 102000003563 TRPV Human genes 0.000 abstract 1
- 108060008564 TRPV Proteins 0.000 abstract 1
- 108010025083 TRPV1 receptor Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/32—Chemical structure of the sugar
- C12N2310/321—2'-O-R Modification
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Ophthalmology & Optometry (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1215857.2A GB201215857D0 (en) | 2012-09-05 | 2012-09-05 | siRNA and their use in methods and compositions for the treatment and/or prevention of eye conditions |
| PCT/EP2013/068245 WO2014037377A1 (en) | 2012-09-05 | 2013-09-04 | Sirna and their use in methods and compositions for the treatment and/or prevention of eye conditions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2015002802A MX2015002802A (es) | 2015-05-15 |
| MX362854B true MX362854B (es) | 2019-02-20 |
Family
ID=47136985
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015002802A MX362854B (es) | 2012-09-05 | 2013-09-04 | Siarn y su uso en los metodos y composiciones para el tratamiento y/o prevencion de enfermedades de los ojos. |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US9808479B2 (OSRAM) |
| EP (1) | EP2893019B1 (OSRAM) |
| JP (2) | JP2015529210A (OSRAM) |
| KR (1) | KR102136539B1 (OSRAM) |
| CN (2) | CN108354944A (OSRAM) |
| AU (1) | AU2013311781B2 (OSRAM) |
| BR (1) | BR112015004469B8 (OSRAM) |
| CA (1) | CA2883040C (OSRAM) |
| CL (1) | CL2015000537A1 (OSRAM) |
| CY (1) | CY1121000T1 (OSRAM) |
| DK (1) | DK2893019T3 (OSRAM) |
| EC (1) | ECSP15009391A (OSRAM) |
| ES (1) | ES2685346T3 (OSRAM) |
| GB (1) | GB201215857D0 (OSRAM) |
| HR (1) | HRP20181079T1 (OSRAM) |
| HU (1) | HUE040096T2 (OSRAM) |
| IL (1) | IL237389B (OSRAM) |
| IN (1) | IN2015DN02501A (OSRAM) |
| LT (1) | LT2893019T (OSRAM) |
| MX (1) | MX362854B (OSRAM) |
| PE (1) | PE20150619A1 (OSRAM) |
| PL (1) | PL2893019T3 (OSRAM) |
| PT (1) | PT2893019T (OSRAM) |
| RS (1) | RS57620B1 (OSRAM) |
| RU (1) | RU2663100C2 (OSRAM) |
| SG (1) | SG11201501386TA (OSRAM) |
| SI (1) | SI2893019T1 (OSRAM) |
| WO (1) | WO2014037377A1 (OSRAM) |
| ZA (1) | ZA201501494B (OSRAM) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA202191537A1 (ru) | 2011-06-30 | 2022-01-31 | Эрроухэд Фармасьютикалс, Инк. | Композиции и способы ингибирования экспрессии генов вируса гепатита в |
| KR20180038465A (ko) | 2015-08-07 | 2018-04-16 | 애로우헤드 파마슈티컬스 인코포레이티드 | Ｂ형 간염 바이러스 감염에 대한 ｒｎａｉ 치료법 |
| JOP20170161A1 (ar) | 2016-08-04 | 2019-01-30 | Arrowhead Pharmaceuticals Inc | عوامل RNAi للعدوى بفيروس التهاب الكبد ب |
| CN113453686B (zh) | 2019-02-15 | 2025-04-15 | 博士伦爱尔兰有限公司 | 治疗眼表痛的方法 |
| JP6994061B2 (ja) | 2019-02-15 | 2022-01-14 | ノバルティス アーゲー | ４－（７－ヒドロキシ－２－イソプロピル－４－オキソ－４ｈ－キナゾリン－３－イル）－ベンゾニトリルの製剤 |
| MX2022004027A (es) * | 2019-10-04 | 2022-07-19 | Senju Pharma Co | Farmaco farmaceutico que contiene derivado de heterocicliden acetamida. |
Family Cites Families (66)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4343794A (en) | 1980-05-06 | 1982-08-10 | Mt. Sinai | Method of reducing intraocular pressure with salts of vanadic acid |
| US4652586A (en) | 1980-11-07 | 1987-03-24 | The General Hospital Corporation | Selective beta-2 adrenergic antagonists for the treatment of glaucoma |
| US4617299A (en) | 1983-12-19 | 1986-10-14 | Knepper Paul A | Method for the prevention of ocular hypertension, treatment of glaucoma and treatment of ocular hypertension |
| US5242943A (en) | 1984-03-28 | 1993-09-07 | William J. Louis | 3-aminopropoxyphenyl derivatives, their preparation and pharmaceutical compositions containing them |
| US4812448A (en) | 1984-10-22 | 1989-03-14 | Knepper Paul A | Method for the prevention of ocular hypertension, treatment of glaucoma and treatment of ocular hypertension |
| US4757089A (en) | 1985-06-14 | 1988-07-12 | Massachusetts Eye And Ear Infirmary | Increasing aqueous humor outflow |
| US5075323A (en) | 1988-08-24 | 1991-12-24 | Aktiebolaget Hassle | Compounds including omeprazole in the treatment of glaucoma |
| US5260059A (en) | 1989-04-14 | 1993-11-09 | The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon Health Sciences University | Treatment of open-angle glaucoma by modulation matrix metalloproteinases and their inhibitor |
| US6372249B1 (en) | 1991-12-16 | 2002-04-16 | Baylor College Of Medicine | Senscent cell-derived inhibitors of DNA synthesis |
| US5464866A (en) | 1992-08-17 | 1995-11-07 | Alcon Laboratories, Inc. | Substituted hydrindanes for the treatment of angiogenesis-dependent diseases |
| US5545626A (en) | 1994-01-19 | 1996-08-13 | The Trustees Of Columbia University In The City Of New York | Method of treating glaucoma with oligonucleotides |
| US5585401A (en) | 1994-12-09 | 1996-12-17 | The Reents Of The University Of California | Method for enhancing outflow of aqueous humor in treatment of glaucoma |
| US20020055536A1 (en) | 1996-09-26 | 2002-05-09 | Dewitte Robert S. | System and method for structure-based drug design that includes accurate prediction of binding free energy |
| US6489307B1 (en) | 1998-09-14 | 2002-12-03 | University Of Florida | Antisense compositions targeted to β1-adrenoceptor-specific mRNA and methods of use |
| AU776150B2 (en) | 1999-01-28 | 2004-08-26 | Medical College Of Georgia Research Institute, Inc. | Composition and method for (in vivo) and (in vitro) attenuation of gene expression using double stranded RNA |
| US6365576B1 (en) | 1999-06-24 | 2002-04-02 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Method for inhibiting herpes infection |
| ATE373724T2 (de) | 2000-12-01 | 2007-10-15 | Max Planck Gesellschaft | Kleine rns moleküle, die rns-interferenz vermitteln |
| US20020165158A1 (en) | 2001-03-27 | 2002-11-07 | King George L. | Methods of modulating angiogenesis |
| US20050148530A1 (en) | 2002-02-20 | 2005-07-07 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA) |
| US20040209832A1 (en) | 2001-11-30 | 2004-10-21 | Mcswiggen James | RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA) |
| US20070049543A1 (en) | 2001-05-18 | 2007-03-01 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of 11 beta-hydroxysteroid dehydrogenase-1 (11 beta-HSD-1) gene expression using short interfering nucleic acid siNA |
| WO2003059267A2 (en) | 2001-12-21 | 2003-07-24 | Rhode Island Hospital | SELECTIVE 11β-HSD INHIBITORS AND METHODS FOR USE THEREOF |
| US7294504B1 (en) | 2001-12-27 | 2007-11-13 | Allele Biotechnology & Pharmaceuticals, Inc. | Methods and compositions for DNA mediated gene silencing |
| GB2406568B (en) | 2002-02-20 | 2005-09-28 | Sirna Therapeutics Inc | RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) |
| AU2003207708A1 (en) | 2002-02-20 | 2003-09-09 | Sirna Therapeutics, Inc. | Rna interference mediated inhibition of map kinase genes |
| JP2006500910A (ja) | 2002-04-18 | 2006-01-12 | アキュイティ ファーマシューティカルズ、インク． | Ｃｎｓと眼の標的遺伝子を特異的に調節するための手段と方法及びその同定法 |
| US20040115641A1 (en) | 2002-12-11 | 2004-06-17 | Isis Pharmaceuticals Inc. | Modulation of ROCK 1 expression |
| AU2003254162A1 (en) | 2002-07-24 | 2004-02-09 | Immusol Incorporated | Single promoter system for making sirna expression cassettes and expression libraries using a polymerase primer hairpin linker |
| JP2005533503A (ja) | 2002-07-24 | 2005-11-10 | イミューソル インコーポレイテッド | 新規なｓｉＲＮＡ遺伝子ライブラリー、その製造方法及び使用 |
| EP3222725A1 (en) | 2002-08-05 | 2017-09-27 | Silence Therapeutics GmbH | Further novel forms of interfering rna molecules |
| US20040029275A1 (en) | 2002-08-10 | 2004-02-12 | David Brown | Methods and compositions for reducing target gene expression using cocktails of siRNAs or constructs expressing siRNAs |
| WO2004029212A2 (en) | 2002-09-25 | 2004-04-08 | University Of Massachusetts | In vivo gene silencing by chemically modified and stable sirna |
| WO2004042024A2 (en) | 2002-11-01 | 2004-05-21 | The Trustees Of The University Of Pennsylvania | COMPOSITIONS AND METHODS FOR siRNA INHIBITION OF HIF-1 ALPHA |
| DE10322662A1 (de) | 2002-11-06 | 2004-10-07 | Grünenthal GmbH | Wirksame und stabile DNA-Enzyme |
| US7250496B2 (en) | 2002-11-14 | 2007-07-31 | Rosetta Genomics Ltd. | Bioinformatically detectable group of novel regulatory genes and uses thereof |
| WO2006006948A2 (en) | 2002-11-14 | 2006-01-19 | Dharmacon, Inc. | METHODS AND COMPOSITIONS FOR SELECTING siRNA OF IMPROVED FUNCTIONALITY |
| JP2006507841A (ja) | 2002-11-14 | 2006-03-09 | ダーマコン， インコーポレイテッド | 機能的ｓｉＲＮＡおよび超機能的ｓｉＲＮＡ |
| US20060257851A1 (en) | 2002-11-26 | 2006-11-16 | Itzhak Bentwich | Bioinformatically detectable group of novel viral regulatory genes and uses thereof |
| US20040167090A1 (en) | 2003-02-21 | 2004-08-26 | Monahan Sean D. | Covalent modification of RNA for in vitro and in vivo delivery |
| GB0307206D0 (en) | 2003-03-28 | 2003-04-30 | Axordia Ltd | Hyperproliferation |
| US20040198640A1 (en) | 2003-04-02 | 2004-10-07 | Dharmacon, Inc. | Stabilized polynucleotides for use in RNA interference |
| WO2004099372A2 (en) | 2003-05-01 | 2004-11-18 | University Of Florida | Anti-scarring ribozymes and methods |
| US20040224405A1 (en) | 2003-05-06 | 2004-11-11 | Dharmacon Inc. | siRNA induced systemic gene silencing in mammalian systems |
| US20060241072A1 (en) | 2003-06-20 | 2006-10-26 | Isis Pharmaceuticals, Inc. | Oligomeric compounds for use in gene modulation |
| MXPA06003949A (es) | 2003-10-07 | 2006-06-27 | Renovis Inc | Compuestos amida como ligandos del canal de ion y su uso. |
| WO2005045037A2 (en) | 2003-10-23 | 2005-05-19 | Sirna Therapeutics, Inc. | RNA INTERFERENCE MEDIATED INHIBITION OF 5-ALPHA REDUCTASE AND ANDROGEN RECEPTOR GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) |
| KR20050039573A (ko) | 2003-10-23 | 2005-04-29 | 주식회사 태평양 | 티오우레아계 유도체의 용해성과 생체이용률이 개선된약제학적 조성물 |
| US20050208658A1 (en) | 2003-11-21 | 2005-09-22 | The University Of Maryland | RNA interference mediated inhibition of 11beta hydroxysteriod dehydrogenase-1 (11beta HSD-1) gene expression |
| CN108175862B (zh) * | 2003-12-03 | 2022-02-08 | 科达治疗（新西兰）有限公司 | 靶向连接蛋白的反义化合物及其使用方法 |
| US7544803B2 (en) | 2004-01-23 | 2009-06-09 | Amgen Inc. | Vanilloid receptor ligands and their use in treatments |
| US20090247604A1 (en) | 2004-02-05 | 2009-10-01 | Intradigm Corporation | RNAi Therapeutics for Treatment of Eye Neovascularization Diseases |
| GB0403600D0 (en) | 2004-02-18 | 2004-03-24 | Trinity College Dublin | Methods and reagents for treating disease |
| EP2636739B1 (en) | 2004-03-12 | 2014-12-10 | Alnylam Pharmaceuticals Inc. | iRNA agents targeting VEGF |
| KR101147147B1 (ko) | 2004-04-01 | 2012-05-25 | 머크 샤프 앤드 돔 코포레이션 | Ｒｎａ 간섭의 오프 타겟 효과 감소를 위한 변형된폴리뉴클레오타이드 |
| WO2005117938A2 (en) | 2004-04-13 | 2005-12-15 | Regents Of The University Of Minnesota | Methods of treating ocular conditions |
| CA2584502A1 (en) | 2004-06-24 | 2006-01-05 | Incyte Corporation | 2-methylpropanamides and their use as pharmaceuticals |
| CA2576233C (en) | 2004-08-10 | 2016-03-15 | Alnylam Pharmaceuticals, Inc. | Conjugate comprising an antagomir and a ligand |
| PT1781787T (pt) | 2004-08-23 | 2017-07-17 | Sylentis Sau | Tratamento de distúrbios oculares caracterizados por uma pressão intraocular elevada por meio de arnsis |
| TW200639253A (en) | 2005-02-01 | 2006-11-16 | Alcon Inc | RNAi-mediated inhibition of ocular targets |
| BRPI0609206A2 (pt) | 2005-03-11 | 2010-03-02 | Alcon Inc | inibiÇço mediada por rnai de proteÍna relacionada frizzled-1 para tratamento de glaucoma |
| GB0521351D0 (en) * | 2005-10-20 | 2005-11-30 | Genomica Sau | Modulation of TRPV expression levels |
| BRPI0715821A2 (pt) * | 2006-08-24 | 2013-07-23 | Alcon Res Ltd | inibiÇço de gremlina mediada por rnai para tratamento de condiÇÕes relacionadas À iop |
| US20110160279A1 (en) | 2007-08-13 | 2011-06-30 | Board Of Trustees Of Southern Illinois University | METHODS FOR TREATMENT AND PREVENTION OF OTOTOXICITY BY siRNA |
| TW200927192A (en) * | 2007-11-19 | 2009-07-01 | Alcon Res Ltd | Use of TRPV1 receptor antagonists for treating dry eye and ocular pain |
| CN201337650Y (zh) * | 2009-01-06 | 2009-11-04 | 河北科技大学 | 一次性药用单剂量液体容器 |
| EP2390327A1 (en) * | 2010-05-27 | 2011-11-30 | Sylentis S.A. | siRNA and their use in methods and compositions for the treatment and/or prevention of eye conditions |
-
2012
- 2012-09-05 GB GBGB1215857.2A patent/GB201215857D0/en not_active Ceased
-
2013
- 2013-09-04 AU AU2013311781A patent/AU2013311781B2/en active Active
- 2013-09-04 RS RS20180877A patent/RS57620B1/sr unknown
- 2013-09-04 DK DK13759707.6T patent/DK2893019T3/en active
- 2013-09-04 US US14/425,459 patent/US9808479B2/en active Active
- 2013-09-04 HR HRP20181079TT patent/HRP20181079T1/hr unknown
- 2013-09-04 PT PT13759707T patent/PT2893019T/pt unknown
- 2013-09-04 JP JP2015530372A patent/JP2015529210A/ja active Pending
- 2013-09-04 IN IN2501DEN2015 patent/IN2015DN02501A/en unknown
- 2013-09-04 PL PL13759707T patent/PL2893019T3/pl unknown
- 2013-09-04 CN CN201810353730.8A patent/CN108354944A/zh active Pending
- 2013-09-04 CN CN201380046215.0A patent/CN104640988A/zh active Pending
- 2013-09-04 SI SI201331090T patent/SI2893019T1/sl unknown
- 2013-09-04 BR BR112015004469A patent/BR112015004469B8/pt active IP Right Grant
- 2013-09-04 LT LTEP13759707.6T patent/LT2893019T/lt unknown
- 2013-09-04 WO PCT/EP2013/068245 patent/WO2014037377A1/en active Application Filing
- 2013-09-04 RU RU2015112121A patent/RU2663100C2/ru active
- 2013-09-04 SG SG11201501386TA patent/SG11201501386TA/en unknown
- 2013-09-04 ES ES13759707.6T patent/ES2685346T3/es active Active
- 2013-09-04 EP EP13759707.6A patent/EP2893019B1/en active Active
- 2013-09-04 KR KR1020157006165A patent/KR102136539B1/ko active Active
- 2013-09-04 MX MX2015002802A patent/MX362854B/es active IP Right Grant
- 2013-09-04 HU HUE13759707A patent/HUE040096T2/hu unknown
- 2013-09-04 PE PE2015000282A patent/PE20150619A1/es not_active Application Discontinuation
- 2013-09-04 CA CA2883040A patent/CA2883040C/en active Active
-
2015
- 2015-02-24 IL IL237389A patent/IL237389B/en active IP Right Grant
- 2015-03-04 CL CL2015000537A patent/CL2015000537A1/es unknown
- 2015-03-04 ZA ZA2015/01494A patent/ZA201501494B/en unknown
- 2015-03-12 EC ECIEPI20159391A patent/ECSP15009391A/es unknown
-
2018
- 2018-05-09 JP JP2018090693A patent/JP6742362B2/ja active Active
- 2018-08-10 CY CY181100845T patent/CY1121000T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PH12015500525A1 (en) | Formulations of enzalutamide | |
| MX356525B (es) | Vectores de virus asociados con adeno (aav) para uso en terapia de genes de coroideremia. | |
| PH12014501738A1 (en) | Piperidino-pyrimidine derivatives for the treatment of viral infections | |
| IN2015DN01156A (OSRAM) | ||
| MX365294B (es) | Inhibidores de proteína cinasa dependiente de adn. | |
| EA201590165A1 (ru) | Сдерживающие злоупотребление фармацевтические композиции для контролируемого высвобождения | |
| MX2013004061A (es) | Analogos de ciclosporina. | |
| PH12018501279A1 (en) | Compositions comprising 15-hepe and methods of using the same | |
| TR201909158T4 (tr) | siRNA ve göz rahatsızlıklarının tedavisi ve/veya önlenmesine yönelik yöntemler ve bileşimlerde kullanımları. | |
| EP2869819A4 (en) | COMPOSITIONS, METHODS AND / OR DEVICES FOR THE PREVENTION AND / OR TREATMENT OF OCULAR DROUGHT DISORDERS | |
| MX362854B (es) | Siarn y su uso en los metodos y composiciones para el tratamiento y/o prevencion de enfermedades de los ojos. | |
| MX2013004062A (es) | Analogos de ciclosporina. | |
| PH12016500495A1 (en) | Compositions for the treatment of hypertension and/or fibrosis | |
| MX363385B (es) | Métodos para el tratamiento de enfermedad de células falciformes y otras condiciones inflamatorias. | |
| GEP20186920B (en) | Halogenated quinazolinthf-amines as pde1 inhibitors | |
| MX2015001648A (es) | Composiciones que comprenden derivados de espicamicina y metodos de uso de los mismos. | |
| EA201590615A1 (ru) | Стимулирующие лактацию композиции на основе фосфатидилсерина | |
| ZA201502181B (en) | Sirna and their use in methods and compositions for the treatment and/or prevention of eye conditions | |
| TN2014000484A1 (en) | Dronedarone for use in leishmaniasis, formulations and associations for use in leishmaniasis. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |