MX362198B - Deteccion de celulas derivadas de tejido de cordon umbilical humano. - Google Patents

Deteccion de celulas derivadas de tejido de cordon umbilical humano.

Info

Publication number
MX362198B
MX362198B MX2014007638A MX2014007638A MX362198B MX 362198 B MX362198 B MX 362198B MX 2014007638 A MX2014007638 A MX 2014007638A MX 2014007638 A MX2014007638 A MX 2014007638A MX 362198 B MX362198 B MX 362198B
Authority
MX
Mexico
Prior art keywords
hutc
cells
markers positive
pbmc
umbilical cord
Prior art date
Application number
MX2014007638A
Other languages
English (en)
Other versions
MX2014007638A (es
Inventor
Haimanti Dorai
Reyna L Favis
Xiang Yao
Yu Sun
Anthony Kihm
Stefanie Rassnick
Original Assignee
Depuy Synthes Products Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Depuy Synthes Products Llc filed Critical Depuy Synthes Products Llc
Publication of MX2014007638A publication Critical patent/MX2014007638A/es
Publication of MX362198B publication Critical patent/MX362198B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70589—CD45

Abstract

La presente invención se refiere a métodos para detectar células terapéuticas alogénicas (tales como células derivadas del tejido de cordón umbilical humano (hUCT)) en sangre; el método incluye los pasos de identificar uno o más marcadores positivos para células terapéuticas alogénicas (por ejemplo, hUTC) y uno o más marcadores positivos para las células mononucleares de sangre periférica humana (PBMC); proporcionar una muestra de sangre de un paciente que se ha tratado con células terapéuticas alogénicas (por ejemplo, hUTC), analizar la muestra utilizando un método de ensayo para detectar uno o más marcadores positivos para PBMC y uno o más marcadores positivos para células terapéuticas alogénicas (por ejemplo, hUTC); y distinguir entre las PBMC y uno o más marcadores positivos para las células terapéuticas alogénicas (por ejemplo, hUTC); en una modalidad, las células son hUTC y los marcadores positivos de hUTC incluyen CD10 y/o CD13 y el uno o más marcadores positivos para PBMC incluye C D45.
MX2014007638A 2011-12-23 2012-12-20 Deteccion de celulas derivadas de tejido de cordon umbilical humano. MX362198B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161579710P 2011-12-23 2011-12-23
PCT/US2012/071072 WO2013096686A1 (en) 2011-12-23 2012-12-20 Detection of human umbilical cord tissue-derived cells

Publications (2)

Publication Number Publication Date
MX2014007638A MX2014007638A (es) 2015-05-15
MX362198B true MX362198B (es) 2019-01-08

Family

ID=47559711

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014007638A MX362198B (es) 2011-12-23 2012-12-20 Deteccion de celulas derivadas de tejido de cordon umbilical humano.

Country Status (17)

Country Link
US (2) US9611513B2 (es)
EP (1) EP2794854B1 (es)
JP (1) JP6301263B2 (es)
KR (1) KR101981450B1 (es)
CN (1) CN104837987B (es)
AU (1) AU2012358810B2 (es)
BR (1) BR112014015424A2 (es)
CA (1) CA2869681A1 (es)
ES (1) ES2676556T3 (es)
HK (2) HK1203550A1 (es)
MX (1) MX362198B (es)
PH (1) PH12014501445B1 (es)
PL (1) PL2794854T3 (es)
RU (1) RU2636220C2 (es)
SG (1) SG11201403465PA (es)
WO (1) WO2013096686A1 (es)
ZA (1) ZA201405407B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2869681A1 (en) 2011-12-23 2013-06-27 Advanced Technologies And Regenerative Medicine, Llc Detection of human umbilical cord tissue-derived cells
CN104678109A (zh) * 2015-03-06 2015-06-03 复旦大学附属中山医院 一种人源性的cd13可溶性蛋白的免疫组化试剂盒及其应用
CN105238751B (zh) * 2015-11-30 2021-07-23 深圳市合一康生物科技股份有限公司 一种脐带组织间充质干细胞的分离培养方法
JP7108537B2 (ja) 2016-04-27 2022-07-28 ロート製薬株式会社 Ｃｄ２０１、ｃｄ４６、ｃｄ５６、ｃｄ１４７及びｃｄ１６５からなる群より選択される少なくとも１種の細胞表面マーカーを発現する間葉系幹細胞及びその調製方法、並びに上記間葉系幹細胞を含む医薬組成物及びその調製方法
US20200264189A1 (en) * 2017-08-18 2020-08-20 University Of South Carolina Detection of Fumarate Ester-Derived Modification in a Test Sample

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US20130190201A1 (en) 2013-07-25
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US9611513B2 (en) 2017-04-04
PH12014501445B1 (en) 2014-10-08
EP2794854B1 (en) 2018-06-20
US20170335409A1 (en) 2017-11-23
BR112014015424A2 (pt) 2018-05-22
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WO2013096686A1 (en) 2013-06-27
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US10724105B2 (en) 2020-07-28
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