MX360479B - Anticuerpos contra microbioma, factores de estres y marcadores de mastocitos como marcadores de diagnostico para ibs. - Google Patents
Anticuerpos contra microbioma, factores de estres y marcadores de mastocitos como marcadores de diagnostico para ibs.Info
- Publication number
- MX360479B MX360479B MX2015004271A MX2015004271A MX360479B MX 360479 B MX360479 B MX 360479B MX 2015004271 A MX2015004271 A MX 2015004271A MX 2015004271 A MX2015004271 A MX 2015004271A MX 360479 B MX360479 B MX 360479B
- Authority
- MX
- Mexico
- Prior art keywords
- ibs
- markers
- microbiome
- antibodies
- mast cell
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/06—Gastro-intestinal diseases
- G01N2800/065—Bowel diseases, e.g. Crohn, ulcerative colitis, IBS
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Rehabilitation Therapy (AREA)
- Rheumatology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
La presente invención se refiere a un método para ayudar en el diagnóstico de síndrome de intestino irritable (IBS) en un sujeto, el método se caracteriza porque comprende: medir el nivel de una disposición de al menos dos marcadores de anticuerpos contra antígenos bacterianos en una muestra biológica tomada del sujeto, en donde al menos un marcador de la disposición es E. coli FliC; aplicar un análisis estadístico al nivel medio de la disposición de marcadores de anticuerpos contra antígenos bacterianos para general un perfil de marcadores de anticuerpos contra antígenos bacterianos; y comparar el perfil de marcadores de anticuerpos contra antígenos bacterianos con un modelo de diagnóstico para determinar si el individuo tiene mayor probabilidad de tener IBS en comparación con ser un control sano.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261710574P | 2012-10-05 | 2012-10-05 | |
US201361871853P | 2013-08-29 | 2013-08-29 | |
PCT/IB2013/059045 WO2014053996A2 (en) | 2012-10-05 | 2013-10-01 | Antibodies to microbiome, stress factors and mast cell markers as diagnostic markers for ibs |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2015004271A MX2015004271A (es) | 2015-08-14 |
MX360479B true MX360479B (es) | 2018-11-05 |
Family
ID=49447585
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015004271A MX360479B (es) | 2012-10-05 | 2013-10-01 | Anticuerpos contra microbioma, factores de estres y marcadores de mastocitos como marcadores de diagnostico para ibs. |
Country Status (10)
Country | Link |
---|---|
US (1) | US10184940B2 (es) |
EP (1) | EP2904395B1 (es) |
JP (1) | JP6329553B2 (es) |
CN (1) | CN104884959B (es) |
AU (1) | AU2013326133B2 (es) |
CA (1) | CA2886991A1 (es) |
HK (1) | HK1213050A1 (es) |
MX (1) | MX360479B (es) |
SG (2) | SG10201702773QA (es) |
WO (1) | WO2014053996A2 (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0720250D0 (en) * | 2007-10-17 | 2007-11-28 | Univ Edinburgh | Immunogenic compositions containing escherichia coli h7 flagella and methods of use thereof |
MX2015015844A (es) * | 2013-05-17 | 2016-03-04 | Basf Se | Proceso para preparar compuestos n-sustituidos de acido 1h-pirazol-5-carboxilico y sus derivados. |
KR20160013163A (ko) | 2013-05-24 | 2016-02-03 | 네스텍 소시에테아노님 | 과민성 대장 증후군 진단을 예측하기 위한 경로 특이적 검정법 |
CA3011215A1 (en) | 2015-11-06 | 2017-05-11 | Vetica Labs, Inc. | Methods of detecting inflammatory markers and treating inflammatory conditions in companion animals |
EP3421616A1 (en) * | 2017-06-29 | 2019-01-02 | Tata Consultancy Services Limited | Method and system for monitoring the gut health of an individual |
AU2018346255A1 (en) * | 2017-10-03 | 2020-04-23 | Seres Therapeutics, Inc. | Manipulation of tryptamine metabolism |
JP6533930B1 (ja) * | 2018-08-23 | 2019-06-26 | 一般社団法人日本農業フロンティア開発機構 | 疾病評価指標算出方法、装置、システム、及び、プログラム、並びに、疾病評価指標を算出するためのモデル作成方法。 |
US11884958B2 (en) | 2019-04-30 | 2024-01-30 | Mayo Foundation For Medical Education And Research | Assessing and treating functional gastrointestinal disorders |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2003298703A1 (en) * | 2002-11-22 | 2004-06-18 | Emory University | Diagnostic tests and methods for diagnosing inflammatory bowel disease |
US20060154276A1 (en) * | 2004-05-13 | 2006-07-13 | Prometheus Laboratories Inc. | Methods of diagnosing inflammatory bowel disease |
US7943328B1 (en) * | 2006-03-03 | 2011-05-17 | Prometheus Laboratories Inc. | Method and system for assisting in diagnosing irritable bowel syndrome |
US20100094560A1 (en) * | 2006-08-15 | 2010-04-15 | Prometheus Laboratories Inc. | Methods for diagnosing irritable bowel syndrome |
US20080085524A1 (en) | 2006-08-15 | 2008-04-10 | Prometheus Laboratories Inc. | Methods for diagnosing irritable bowel syndrome |
WO2011027971A2 (ko) * | 2009-09-01 | 2011-03-10 | 주식회사이언메딕스 | 장내 공생 세균유래 세포밖 소포체, 및 이를 이용한 질병모델, 백신, 후보 약물 탐색 방법, 및 진단 방법 |
CA2778539A1 (en) * | 2009-10-30 | 2011-05-05 | Hua Gong | Methods for diagnosing irritable bowel syndrome |
-
2013
- 2013-10-01 SG SG10201702773QA patent/SG10201702773QA/en unknown
- 2013-10-01 EP EP13779635.5A patent/EP2904395B1/en not_active Not-in-force
- 2013-10-01 MX MX2015004271A patent/MX360479B/es active IP Right Grant
- 2013-10-01 AU AU2013326133A patent/AU2013326133B2/en not_active Expired - Fee Related
- 2013-10-01 JP JP2015535149A patent/JP6329553B2/ja not_active Expired - Fee Related
- 2013-10-01 SG SG11201502641YA patent/SG11201502641YA/en unknown
- 2013-10-01 CA CA2886991A patent/CA2886991A1/en not_active Abandoned
- 2013-10-01 CN CN201380063446.2A patent/CN104884959B/zh not_active Expired - Fee Related
- 2013-10-01 WO PCT/IB2013/059045 patent/WO2014053996A2/en active Application Filing
-
2015
- 2015-03-30 US US14/673,660 patent/US10184940B2/en active Active
-
2016
- 2016-01-26 HK HK16100851.0A patent/HK1213050A1/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US20150346200A1 (en) | 2015-12-03 |
CN104884959A (zh) | 2015-09-02 |
EP2904395B1 (en) | 2018-09-05 |
SG11201502641YA (en) | 2015-05-28 |
US10184940B2 (en) | 2019-01-22 |
WO2014053996A3 (en) | 2014-05-30 |
HK1213050A1 (zh) | 2016-06-24 |
AU2013326133B2 (en) | 2019-07-04 |
CA2886991A1 (en) | 2014-04-10 |
SG10201702773QA (en) | 2017-06-29 |
CN104884959B (zh) | 2017-12-01 |
AU2013326133A1 (en) | 2015-04-23 |
EP2904395A2 (en) | 2015-08-12 |
JP2015533213A (ja) | 2015-11-19 |
JP6329553B2 (ja) | 2018-05-23 |
MX2015004271A (es) | 2015-08-14 |
WO2014053996A2 (en) | 2014-04-10 |
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Legal Events
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FG | Grant or registration |