MX360479B - Anticuerpos contra microbioma, factores de estres y marcadores de mastocitos como marcadores de diagnostico para ibs. - Google Patents

Anticuerpos contra microbioma, factores de estres y marcadores de mastocitos como marcadores de diagnostico para ibs.

Info

Publication number
MX360479B
MX360479B MX2015004271A MX2015004271A MX360479B MX 360479 B MX360479 B MX 360479B MX 2015004271 A MX2015004271 A MX 2015004271A MX 2015004271 A MX2015004271 A MX 2015004271A MX 360479 B MX360479 B MX 360479B
Authority
MX
Mexico
Prior art keywords
ibs
markers
microbiome
antibodies
mast cell
Prior art date
Application number
MX2015004271A
Other languages
English (en)
Other versions
MX2015004271A (es
Inventor
Singh Sharat
Lockton Steven
Chi-Kwan Ling Nicholas
Wang Shui-Long
Princen Fred
Westin Stefan
Original Assignee
Nestec Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nestec Sa filed Critical Nestec Sa
Publication of MX2015004271A publication Critical patent/MX2015004271A/es
Publication of MX360479B publication Critical patent/MX360479B/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/06—Gastro-intestinal diseases
    • G01N2800/065—Bowel diseases, e.g. Crohn, ulcerative colitis, IBS
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La presente invención se refiere a un método para ayudar en el diagnóstico de síndrome de intestino irritable (IBS) en un sujeto, el método se caracteriza porque comprende: medir el nivel de una disposición de al menos dos marcadores de anticuerpos contra antígenos bacterianos en una muestra biológica tomada del sujeto, en donde al menos un marcador de la disposición es E. coli FliC; aplicar un análisis estadístico al nivel medio de la disposición de marcadores de anticuerpos contra antígenos bacterianos para general un perfil de marcadores de anticuerpos contra antígenos bacterianos; y comparar el perfil de marcadores de anticuerpos contra antígenos bacterianos con un modelo de diagnóstico para determinar si el individuo tiene mayor probabilidad de tener IBS en comparación con ser un control sano.
MX2015004271A 2012-10-05 2013-10-01 Anticuerpos contra microbioma, factores de estres y marcadores de mastocitos como marcadores de diagnostico para ibs. MX360479B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261710574P 2012-10-05 2012-10-05
US201361871853P 2013-08-29 2013-08-29
PCT/IB2013/059045 WO2014053996A2 (en) 2012-10-05 2013-10-01 Antibodies to microbiome, stress factors and mast cell markers as diagnostic markers for ibs

Publications (2)

Publication Number Publication Date
MX2015004271A MX2015004271A (es) 2015-08-14
MX360479B true MX360479B (es) 2018-11-05

Family

ID=49447585

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015004271A MX360479B (es) 2012-10-05 2013-10-01 Anticuerpos contra microbioma, factores de estres y marcadores de mastocitos como marcadores de diagnostico para ibs.

Country Status (10)

Country Link
US (1) US10184940B2 (es)
EP (1) EP2904395B1 (es)
JP (1) JP6329553B2 (es)
CN (1) CN104884959B (es)
AU (1) AU2013326133B2 (es)
CA (1) CA2886991A1 (es)
HK (1) HK1213050A1 (es)
MX (1) MX360479B (es)
SG (2) SG10201702773QA (es)
WO (1) WO2014053996A2 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0720250D0 (en) * 2007-10-17 2007-11-28 Univ Edinburgh Immunogenic compositions containing escherichia coli h7 flagella and methods of use thereof
MX2015015844A (es) * 2013-05-17 2016-03-04 Basf Se Proceso para preparar compuestos n-sustituidos de acido 1h-pirazol-5-carboxilico y sus derivados.
KR20160013163A (ko) 2013-05-24 2016-02-03 네스텍 소시에테아노님 과민성 대장 증후군 진단을 예측하기 위한 경로 특이적 검정법
CA3011215A1 (en) 2015-11-06 2017-05-11 Vetica Labs, Inc. Methods of detecting inflammatory markers and treating inflammatory conditions in companion animals
EP3421616A1 (en) * 2017-06-29 2019-01-02 Tata Consultancy Services Limited Method and system for monitoring the gut health of an individual
AU2018346255A1 (en) * 2017-10-03 2020-04-23 Seres Therapeutics, Inc. Manipulation of tryptamine metabolism
JP6533930B1 (ja) * 2018-08-23 2019-06-26 一般社団法人日本農業フロンティア開発機構 疾病評価指標算出方法、装置、システム、及び、プログラム、並びに、疾病評価指標を算出するためのモデル作成方法。
US11884958B2 (en) 2019-04-30 2024-01-30 Mayo Foundation For Medical Education And Research Assessing and treating functional gastrointestinal disorders

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003298703A1 (en) * 2002-11-22 2004-06-18 Emory University Diagnostic tests and methods for diagnosing inflammatory bowel disease
US20060154276A1 (en) * 2004-05-13 2006-07-13 Prometheus Laboratories Inc. Methods of diagnosing inflammatory bowel disease
US7943328B1 (en) * 2006-03-03 2011-05-17 Prometheus Laboratories Inc. Method and system for assisting in diagnosing irritable bowel syndrome
US20100094560A1 (en) * 2006-08-15 2010-04-15 Prometheus Laboratories Inc. Methods for diagnosing irritable bowel syndrome
US20080085524A1 (en) 2006-08-15 2008-04-10 Prometheus Laboratories Inc. Methods for diagnosing irritable bowel syndrome
WO2011027971A2 (ko) * 2009-09-01 2011-03-10 주식회사이언메딕스 장내 공생 세균유래 세포밖 소포체, 및 이를 이용한 질병모델, 백신, 후보 약물 탐색 방법, 및 진단 방법
CA2778539A1 (en) * 2009-10-30 2011-05-05 Hua Gong Methods for diagnosing irritable bowel syndrome

Also Published As

Publication number Publication date
US20150346200A1 (en) 2015-12-03
CN104884959A (zh) 2015-09-02
EP2904395B1 (en) 2018-09-05
SG11201502641YA (en) 2015-05-28
US10184940B2 (en) 2019-01-22
WO2014053996A3 (en) 2014-05-30
HK1213050A1 (zh) 2016-06-24
AU2013326133B2 (en) 2019-07-04
CA2886991A1 (en) 2014-04-10
SG10201702773QA (en) 2017-06-29
CN104884959B (zh) 2017-12-01
AU2013326133A1 (en) 2015-04-23
EP2904395A2 (en) 2015-08-12
JP2015533213A (ja) 2015-11-19
JP6329553B2 (ja) 2018-05-23
MX2015004271A (es) 2015-08-14
WO2014053996A2 (en) 2014-04-10

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