MX358541B - Metodos para predecir el riesgo de desarrollar hipertension. - Google Patents
Metodos para predecir el riesgo de desarrollar hipertension.Info
- Publication number
- MX358541B MX358541B MX2015002061A MX2015002061A MX358541B MX 358541 B MX358541 B MX 358541B MX 2015002061 A MX2015002061 A MX 2015002061A MX 2015002061 A MX2015002061 A MX 2015002061A MX 358541 B MX358541 B MX 358541B
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- developing hypertension
- risk
- predicting risk
- hypertension
- Prior art date
Links
- 206010020772 Hypertension Diseases 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 4
- 239000000090 biomarker Substances 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
- G01N33/6869—Interleukin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/52—Assays involving cytokines
- G01N2333/54—Interleukins [IL]
- G01N2333/545—IL-1
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/321—Arterial hypertension
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
La presente invención se refiere a un método para evaluar el riesgo de desarrollar hipertensión en un sujeto sano quien no tiene hipertensión, el método caracterizado porque comprende: determinar un nivel de ST2 soluble en una muestra biológica de un sujeto; comparar el nivel de ST2 en la muestra biológica a un nivel de referencia de ST2 soluble; e identificar un sujeto que tiene un nivel elevado de ST2 soluble en la muestra biológica comparado con el nivel de referencia de la ST2 soluble por tener un riesgo incrementado de desarrollar hipertensión, o identificar un sujeto que tiene un bajo nivel disminuido de ST2 soluble en una muestra biológica comparado con el nivel de referencia de la ST2 soluble por tener un riesgo disminuido de desarrollar hipotensión.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261683956P | 2012-08-16 | 2012-08-16 | |
| PCT/US2013/055417 WO2014028875A1 (en) | 2012-08-16 | 2013-08-16 | Methods for predicting risk of developing hypertension |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2015002061A MX2015002061A (es) | 2015-06-05 |
| MX358541B true MX358541B (es) | 2018-08-24 |
Family
ID=50100476
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015002061A MX358541B (es) | 2012-08-16 | 2013-08-16 | Metodos para predecir el riesgo de desarrollar hipertension. |
| MX2018010151A MX382403B (es) | 2012-08-16 | 2013-08-16 | Métodos para predecir el riesgo de desarrollar hipertensión. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2018010151A MX382403B (es) | 2012-08-16 | 2013-08-16 | Métodos para predecir el riesgo de desarrollar hipertensión. |
Country Status (16)
| Country | Link |
|---|---|
| US (3) | US9523696B2 (es) |
| EP (2) | EP2885641B1 (es) |
| JP (3) | JP6298466B2 (es) |
| CN (2) | CN107478841A (es) |
| AU (2) | AU2013302451B2 (es) |
| CA (1) | CA2882133A1 (es) |
| DK (1) | DK2885641T3 (es) |
| ES (1) | ES2656897T3 (es) |
| HK (1) | HK1250782A1 (es) |
| IN (1) | IN2015DN01259A (es) |
| MX (2) | MX358541B (es) |
| NO (1) | NO2983845T3 (es) |
| PL (1) | PL2885641T3 (es) |
| RU (2) | RU2019107598A (es) |
| SG (2) | SG11201501200XA (es) |
| WO (1) | WO2014028875A1 (es) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002038794A2 (en) | 2000-11-09 | 2002-05-16 | The Brigham And Women's Hospital, Inc. | Cardiovascular disease diagnostic and therapeutic targets |
| US7670769B2 (en) | 2002-05-09 | 2010-03-02 | The Brigham And Women's Hospital, Inc. | IL1RL-1 as a cardiovascular disease marker and therapeutic target |
| PL2386860T4 (pl) | 2006-04-24 | 2015-09-30 | Critical Care Diagnostics Inc | Przewidywanie śmiertelności i wykrywanie poważnej choroby |
| PT2021796E (pt) | 2006-05-01 | 2012-04-19 | Critical Care Diagnostics Inc | Diagnóstico de doença cardiovascular |
| SI2269063T1 (sl) | 2008-04-18 | 2014-01-31 | Critical Care Diagnostics, Inc. | Napoved tveganja večjih neugodnih pojavov na srcu |
| RU2625014C2 (ru) | 2010-04-09 | 2017-07-11 | Критикал Кэа Дайэгностикс, Инк. | Антитела против растворимого st-2 человека и способы анализа |
| CN106940375B (zh) | 2011-03-17 | 2019-03-08 | 重症监护诊断股份有限公司 | 预测不良临床结果的风险的方法 |
| BR112014001283A2 (pt) | 2011-07-18 | 2017-02-21 | Critical Care Diagnostics Inc | métodos de tratamento de doenças cardiovasculares e prevenção da eficácia da terapia de exercício |
| MX357740B (es) | 2012-05-18 | 2018-07-23 | Critical Care Diagnostics Inc | Métodos para determinar el pronóstico del tratamiento de un sujeto con un desfibrilador cardíaco implantado, un dispositivo de tratamiento de resincronización cardíaca o un dispositivo combinado de desfibrilador cardíaco implantado y de resincronización cardíaca. |
| US10265081B2 (en) * | 2012-08-09 | 2019-04-23 | Smith & Nephew, Inc. | Intra-operatively adjustable cutting guide |
| CA2882133A1 (en) | 2012-08-16 | 2014-02-20 | Critical Care Diagnostics, Inc. | Methods for predicting risk of developing hypertension |
| HK1212057A1 (en) | 2012-08-21 | 2016-06-03 | 重症监护诊断股份有限公司 | Multimarker risk stratification |
| CA2961340C (en) | 2014-09-26 | 2023-10-17 | Somalogic, Inc. | Cardiovascular risk event prediction and uses thereof |
| CA2960297A1 (en) | 2014-11-10 | 2016-05-19 | Genentech, Inc. | Anti-interleukin-33 antibodies and uses thereof |
| EP3218515B1 (en) | 2014-11-10 | 2023-04-26 | F. Hoffmann-La Roche AG | Therapeutic and diagnostic methods for il-33-mediated disorders |
| US10079073B2 (en) | 2014-12-11 | 2018-09-18 | Critical Care Diagnostics, Inc. | Test apparatus and methods for ST2 cardiac biomarker |
| US10324089B2 (en) | 2014-12-11 | 2019-06-18 | Critical Care Diagnostics, Inc. | Test apparatus and methods for ST2 cardiac biomarker |
| RU2677611C1 (ru) * | 2018-04-16 | 2019-01-17 | Федеральное государственное бюджетное научное учреждение "Томский национальный исследовательский медицинский центр Российской академии наук" (Томский НИМЦ) | Способ прогнозирования неблагоприятных сердечно-сосудистых событий в течение 12 месяцев у больных хронической сердечной недостаточностью с рецидивом стенокардии после реваскуляризации миокарда |
| US11551817B2 (en) | 2020-01-14 | 2023-01-10 | International Business Machines Corporation | Assessing unreliability of clinical risk prediction |
| CA3174680A1 (en) | 2020-03-13 | 2021-09-16 | Genentech, Inc. | Anti-interleukin-33 antibodies and uses thereof |
| US20220218292A1 (en) * | 2021-01-14 | 2022-07-14 | Apple Inc. | User interfaces for monitoring health |
| RU2767266C1 (ru) * | 2021-05-27 | 2022-03-17 | Федеральное государственное бюджетное научное учреждение «Томский национальный исследовательский медицинский центр Российской академии наук» (Томский НИМЦ) | Способ прогнозирования однолетнего риска неблагоприятных сердечно-сосудистых событий у мужчин после декомпенсации хронической сердечной недостаточности с сохранной фракцией выброса левого желудочка сердца и синдромом обструктивного апноэ во сне |
| CN114350670B (zh) * | 2022-03-18 | 2022-06-14 | 北京市心肺血管疾病研究所 | 特异性识别可溶性st2蛋白的核酸适配体及其应用 |
| CN115188465B (zh) * | 2022-06-27 | 2025-09-26 | 深圳技术大学 | 急性加重的预测方法及装置、电子设备和存储介质 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2001218871A1 (en) | 2000-03-21 | 2001-10-03 | Takao Arai | Monoclonal antibody and method and kit for the immunoassay of soluble human st2 with the use of the same |
| WO2002038794A2 (en) | 2000-11-09 | 2002-05-16 | The Brigham And Women's Hospital, Inc. | Cardiovascular disease diagnostic and therapeutic targets |
| CN1613012A (zh) * | 2001-11-05 | 2005-05-04 | 布赖汉姆妇女医院 | 可溶的cd40l(cd154)作为动脉粥样硬化的疾病的先兆标记 |
| US7670769B2 (en) * | 2002-05-09 | 2010-03-02 | The Brigham And Women's Hospital, Inc. | IL1RL-1 as a cardiovascular disease marker and therapeutic target |
| WO2005042795A2 (en) | 2003-10-31 | 2005-05-12 | Queststar Medical, Inc. | Plasma polymerization of atomically modified surfaces |
| JP5921052B2 (ja) * | 2004-12-03 | 2016-05-24 | ロード アイランド ホスピタル | アルツハイマー病の検査 |
| PL2386860T4 (pl) | 2006-04-24 | 2015-09-30 | Critical Care Diagnostics Inc | Przewidywanie śmiertelności i wykrywanie poważnej choroby |
| ATE517341T1 (de) | 2006-04-27 | 2011-08-15 | Critical Care Diagnostics Inc | Interleukin-33 (il-33) zur diagnose und vorhersage von herz-gefäss-erkrankungen |
| PT2021796E (pt) | 2006-05-01 | 2012-04-19 | Critical Care Diagnostics Inc | Diagnóstico de doença cardiovascular |
| DK2019965T3 (en) | 2006-05-02 | 2015-07-20 | Critical Care Diagnostics Inc | DIFFERENTIAL BETWEEN LUNG AND Cardiovascular Disease |
| WO2007130627A2 (en) * | 2006-05-04 | 2007-11-15 | The Brigham And Women's Hospital, Inc. | Il-33 in the treatment and diagnosis of diseases and disorders |
| GB0703514D0 (en) * | 2007-02-23 | 2007-04-04 | Univ Ulster | Use of riboflavin |
| WO2008131039A2 (en) * | 2007-04-16 | 2008-10-30 | Board Of Regents, The University Of Texas System | Cardibioindex/cardibioscore and utility of salivary proteome in cardiovascular diagnostics |
| EP2293078B1 (en) * | 2007-08-03 | 2011-11-09 | B.R.A.H.M.S GmbH | Method for diagnosis of a bacterial infection |
| SI2269063T1 (sl) | 2008-04-18 | 2014-01-31 | Critical Care Diagnostics, Inc. | Napoved tveganja večjih neugodnih pojavov na srcu |
| JP5711131B2 (ja) * | 2008-10-07 | 2015-04-30 | ベー.エル.アー.ハー.エム.エス ゲゼルシャフト ミット ベシュレンクテル ハフツング | 最初の有害事象の予測のためのバイオマーカー |
| EP2470910B1 (en) * | 2009-08-28 | 2017-01-11 | B.R.A.H.M.S GmbH | Procalcitonin for the prognosis of adverse events |
| RU2625014C2 (ru) | 2010-04-09 | 2017-07-11 | Критикал Кэа Дайэгностикс, Инк. | Антитела против растворимого st-2 человека и способы анализа |
| GB201013151D0 (en) * | 2010-08-04 | 2010-09-22 | Isis Innovation | Diagnostic method |
| CN106940375B (zh) | 2011-03-17 | 2019-03-08 | 重症监护诊断股份有限公司 | 预测不良临床结果的风险的方法 |
| BR112014001283A2 (pt) | 2011-07-18 | 2017-02-21 | Critical Care Diagnostics Inc | métodos de tratamento de doenças cardiovasculares e prevenção da eficácia da terapia de exercício |
| US20130157290A1 (en) * | 2011-12-16 | 2013-06-20 | Yves Levy | Soluble st2 as a marker for disease |
| MX357740B (es) | 2012-05-18 | 2018-07-23 | Critical Care Diagnostics Inc | Métodos para determinar el pronóstico del tratamiento de un sujeto con un desfibrilador cardíaco implantado, un dispositivo de tratamiento de resincronización cardíaca o un dispositivo combinado de desfibrilador cardíaco implantado y de resincronización cardíaca. |
| CA2882133A1 (en) | 2012-08-16 | 2014-02-20 | Critical Care Diagnostics, Inc. | Methods for predicting risk of developing hypertension |
| HK1212057A1 (en) | 2012-08-21 | 2016-06-03 | 重症监护诊断股份有限公司 | Multimarker risk stratification |
| CN113744876A (zh) | 2014-01-10 | 2021-12-03 | 重症监护诊断股份有限公司 | 用于测定心力衰竭风险的方法和系统 |
| USD770057S1 (en) | 2014-04-14 | 2016-10-25 | Critical Care Diagnostics, Inc. | Blood test kit |
| USD800332S1 (en) * | 2014-09-23 | 2017-10-17 | Critical Care Diagnostics, Inc. | Blood test kit |
| USD800333S1 (en) * | 2014-09-23 | 2017-10-17 | Critical Care Diagnostics, Inc. | Blood test kit |
| US10079073B2 (en) | 2014-12-11 | 2018-09-18 | Critical Care Diagnostics, Inc. | Test apparatus and methods for ST2 cardiac biomarker |
| US10324089B2 (en) | 2014-12-11 | 2019-06-18 | Critical Care Diagnostics, Inc. | Test apparatus and methods for ST2 cardiac biomarker |
-
2013
- 2013-08-16 CA CA2882133A patent/CA2882133A1/en not_active Abandoned
- 2013-08-16 PL PL13830006T patent/PL2885641T3/pl unknown
- 2013-08-16 US US13/969,116 patent/US9523696B2/en active Active
- 2013-08-16 CN CN201710532173.1A patent/CN107478841A/zh active Pending
- 2013-08-16 JP JP2015527668A patent/JP6298466B2/ja not_active Expired - Fee Related
- 2013-08-16 ES ES13830006.6T patent/ES2656897T3/es active Active
- 2013-08-16 SG SG11201501200XA patent/SG11201501200XA/en unknown
- 2013-08-16 EP EP13830006.6A patent/EP2885641B1/en not_active Not-in-force
- 2013-08-16 MX MX2015002061A patent/MX358541B/es active IP Right Grant
- 2013-08-16 RU RU2019107598A patent/RU2019107598A/ru unknown
- 2013-08-16 EP EP17191053.2A patent/EP3282258A1/en not_active Withdrawn
- 2013-08-16 AU AU2013302451A patent/AU2013302451B2/en not_active Ceased
- 2013-08-16 RU RU2015108959A patent/RU2683026C2/ru active
- 2013-08-16 DK DK13830006.6T patent/DK2885641T3/da active
- 2013-08-16 WO PCT/US2013/055417 patent/WO2014028875A1/en not_active Ceased
- 2013-08-16 MX MX2018010151A patent/MX382403B/es unknown
- 2013-08-16 CN CN201380052763.4A patent/CN104737023B/zh not_active Expired - Fee Related
- 2013-08-16 SG SG10201704311VA patent/SG10201704311VA/en unknown
-
2014
- 2014-04-10 NO NO14716337A patent/NO2983845T3/no unknown
-
2015
- 2015-02-16 IN IN1259DEN2015 patent/IN2015DN01259A/en unknown
- 2015-09-08 HK HK18110132.8A patent/HK1250782A1/en unknown
-
2016
- 2016-12-19 US US15/382,810 patent/US10041957B2/en not_active Expired - Fee Related
-
2018
- 2018-02-23 JP JP2018030232A patent/JP6757757B2/ja not_active Expired - Fee Related
- 2018-08-03 US US16/054,378 patent/US20180335437A1/en not_active Abandoned
-
2019
- 2019-04-15 AU AU2019202597A patent/AU2019202597A1/en not_active Abandoned
-
2020
- 2020-08-31 JP JP2020145790A patent/JP2020196757A/ja active Pending
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