MX358829B - Vacunas conjugadas de salmonela. - Google Patents

Vacunas conjugadas de salmonela.

Info

Publication number
MX358829B
MX358829B MX2016006001A MX2016006001A MX358829B MX 358829 B MX358829 B MX 358829B MX 2016006001 A MX2016006001 A MX 2016006001A MX 2016006001 A MX2016006001 A MX 2016006001A MX 358829 B MX358829 B MX 358829B
Authority
MX
Mexico
Prior art keywords
conjugate vaccines
salmonella
salmonella conjugate
compositions
conjugate
Prior art date
Application number
MX2016006001A
Other languages
English (en)
Other versions
MX2016006001A (es
Inventor
Micoli Francesca
Alexander Maclennan Calman
Bartle Martin Laura
James Saul Allan
Original Assignee
Glaxosmithkline Biologicals Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biologicals Sa filed Critical Glaxosmithkline Biologicals Sa
Publication of MX2016006001A publication Critical patent/MX2016006001A/es
Publication of MX358829B publication Critical patent/MX358829B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/6415—Toxins or lectins, e.g. clostridial toxins or Pseudomonas exotoxins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A61K39/0275—Salmonella
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
    • A61K2039/627—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier characterised by the linker
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • Toxicology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención se refiere a un conjugado basado en el polisacárido Vi que está fragmentado y una proteína portadora, a composiciones que comprenden dicho conjugado, y a métodos para la elaboración de dichos conjugados y composiciones.
MX2016006001A 2013-11-08 2014-11-07 Vacunas conjugadas de salmonela. MX358829B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20130192176 EP2870974A1 (en) 2013-11-08 2013-11-08 Salmonella conjugate vaccines
PCT/IB2014/065869 WO2015068129A1 (en) 2013-11-08 2014-11-07 Salmonella conjugate vaccines

Publications (2)

Publication Number Publication Date
MX2016006001A MX2016006001A (es) 2016-07-22
MX358829B true MX358829B (es) 2018-09-05

Family

ID=49551548

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016006001A MX358829B (es) 2013-11-08 2014-11-07 Vacunas conjugadas de salmonela.

Country Status (15)

Country Link
US (1) US10098947B2 (es)
EP (2) EP2870974A1 (es)
JP (1) JP6289632B2 (es)
KR (2) KR20160079874A (es)
CN (1) CN105828839B (es)
AU (1) AU2014347722B2 (es)
BR (1) BR112016010072B1 (es)
CA (1) CA2929114C (es)
EA (1) EA033491B1 (es)
ES (1) ES2828039T3 (es)
IL (1) IL245217B (es)
MX (1) MX358829B (es)
SG (1) SG11201603306TA (es)
WO (1) WO2015068129A1 (es)
ZA (1) ZA201602834B (es)

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KR102428253B1 (ko) * 2016-03-15 2022-08-02 엠에스디 웰컴 트러스트 힐레맨 랩스 피브이티. 리미티드 신규한 다당류-단백질 접합체 및 이의 제조방법
CN110214022A (zh) * 2016-11-25 2019-09-06 葛兰素史密丝克莱恩生物有限公司 免疫原性缀合物及其用途
US20210401960A1 (en) * 2018-11-10 2021-12-30 Bharat Biotech International Limited Multivalent glycoconjugates immunogenic compositions
KR102574882B1 (ko) * 2019-03-18 2023-09-04 얀센 파마슈티칼즈, 인코포레이티드 대장균 o-항원 다당류의 바이오컨쥬게이트의 생성 방법, 이의 조성물 및 이의 사용 방법
CN110018253A (zh) * 2019-04-15 2019-07-16 艾美卫信生物药业（浙江）有限公司 一种生物制品中游离蛋白含量的高效液相测定方法
CA3161857A1 (en) 2019-11-22 2021-05-27 Glaxosmithkline Biologicals Sa Dosage and administration of a bacterial saccharide glycoconjugate vaccine
KR102493192B1 (ko) * 2021-07-20 2023-01-30 에스케이바이오사이언스(주) 살모넬라 타이피 유래의 피막 다당류-단백질 접합체를 포함하는 백신 조성물

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Also Published As

Publication number Publication date
EP3065781A1 (en) 2016-09-14
BR112016010072B1 (pt) 2021-06-08
EP2870974A1 (en) 2015-05-13
US20160263213A1 (en) 2016-09-15
KR102112663B1 (ko) 2020-05-19
IL245217A0 (en) 2016-06-30
CN105828839B (zh) 2020-02-14
ZA201602834B (en) 2020-01-29
WO2015068129A1 (en) 2015-05-14
KR20160079874A (ko) 2016-07-06
JP6289632B2 (ja) 2018-03-07
CA2929114C (en) 2023-08-22
US10098947B2 (en) 2018-10-16
CA2929114A1 (en) 2015-05-14
KR20190015641A (ko) 2019-02-13
EA033491B1 (ru) 2019-10-31
JP2016536317A (ja) 2016-11-24
AU2014347722A1 (en) 2016-06-02
AU2014347722B2 (en) 2017-10-26
IL245217B (en) 2021-03-25
EA201690857A1 (ru) 2016-10-31
MX2016006001A (es) 2016-07-22
EP3065781B1 (en) 2020-08-05
SG11201603306TA (en) 2016-05-30
BR112016010072A8 (pt) 2020-04-14
ES2828039T3 (es) 2021-05-25
CN105828839A (zh) 2016-08-03

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