MX355785B - Composicions y metodos para la biosintesis de vainillina o de beta-d-glucosido de vainillina. - Google Patents

Composicions y metodos para la biosintesis de vainillina o de beta-d-glucosido de vainillina.

Info

Publication number
MX355785B
MX355785B MX2014001571A MX2014001571A MX355785B MX 355785 B MX355785 B MX 355785B MX 2014001571 A MX2014001571 A MX 2014001571A MX 2014001571 A MX2014001571 A MX 2014001571A MX 355785 B MX355785 B MX 355785B
Authority
MX
Mexico
Prior art keywords
vanillin
glucoside
beta
biosynthesis
compositions
Prior art date
Application number
MX2014001571A
Other languages
English (en)
Other versions
MX2014001571A (es
Inventor
Hansen Joergen
Halkjaer Hansen Esben
m sheridan Joseph
R Heal Jonathan
d o hamilton William
Polur Honey
Original Assignee
Int Flavors & Fragrances Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Int Flavors & Fragrances Inc filed Critical Int Flavors & Fragrances Inc
Publication of MX2014001571A publication Critical patent/MX2014001571A/es
Publication of MX355785B publication Critical patent/MX355785B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
    • C12N9/1007—Methyltransferases (general) (2.1.1.)
    • C12N9/1011—Catechol O-methyltransferase (2.1.1.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/46—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y201/00—Transferases transferring one-carbon groups (2.1)
    • C12Y201/01—Methyltransferases (2.1.1)
    • C12Y201/01006—Catechol O-methyltransferase (2.1.1.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/01—Hydro-lyases (4.2.1)
    • C12Y402/01118—3-Dehydroshikimate dehydratase (4.2.1.118)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • C07K14/395—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts from Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8221—Transit peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01025—Shikimate dehydrogenase (1.1.1.25)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La presente invención se refiere a los microorganismos, plantas, y células vegetales recombinantes que se han diseñado para expresar un polipéptido AROM mutante y/o un polipéptido catecol-O-metiltransferasa mutante individualmente o en combinación con una o más enzimas biosintéticas de vainillina o UDP- glicosiltransferasas (UGT, por sus siglas en inglés). Tales microorganismos, plantas, o células vegetales pueden producir la vainillina o el beta-D-glucósido de vainillina.
MX2014001571A 2011-08-08 2012-08-07 Composicions y metodos para la biosintesis de vainillina o de beta-d-glucosido de vainillina. MX355785B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161521090P 2011-08-08 2011-08-08
US201161522096P 2011-08-10 2011-08-10
PCT/US2012/049842 WO2013022881A1 (en) 2011-08-08 2012-08-07 Compositions and methods for the biosynthesis of vanillin or vanillin beta-d-glucoside

Publications (2)

Publication Number Publication Date
MX2014001571A MX2014001571A (es) 2014-09-08
MX355785B true MX355785B (es) 2018-04-30

Family

ID=47668880

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2014001571A MX355785B (es) 2011-08-08 2012-08-07 Composicions y metodos para la biosintesis de vainillina o de beta-d-glucosido de vainillina.
MX2018005276A MX392155B (es) 2011-08-08 2012-08-07 Composiciones y metodos para la biosintesis de vainillina o de beta-d-glucosido de vainillina.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2018005276A MX392155B (es) 2011-08-08 2012-08-07 Composiciones y metodos para la biosintesis de vainillina o de beta-d-glucosido de vainillina.

Country Status (7)

Country Link
US (3) US10208293B2 (es)
EP (3) EP2742126B1 (es)
CN (3) CN103987840A (es)
BR (1) BR112014003041B1 (es)
ES (2) ES2730102T3 (es)
MX (2) MX355785B (es)
WO (1) WO2013022881A1 (es)

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Also Published As

Publication number Publication date
CN108570464B (zh) 2021-12-21
WO2013022881A8 (en) 2013-03-21
ES2730102T3 (es) 2019-11-08
US10208293B2 (en) 2019-02-19
BR112014003041A2 (pt) 2017-10-17
US20190136270A1 (en) 2019-05-09
CN103987840A (zh) 2014-08-13
CN105063104A (zh) 2015-11-18
EP3514226B1 (en) 2023-03-29
CN108570464A (zh) 2018-09-25
US20140245496A1 (en) 2014-08-28
MX392155B (es) 2025-03-21
US11008592B2 (en) 2021-05-18
EP3118304A1 (en) 2017-01-18
EP2742126B1 (en) 2018-11-07
ES2719304T3 (es) 2019-07-09
EP2742126A1 (en) 2014-06-18
BR112014003041B1 (pt) 2021-10-13
EP2742126A4 (en) 2015-04-22
CN105063104B (zh) 2019-08-13
EP3514226A1 (en) 2019-07-24
EP3118304B1 (en) 2019-03-13
US20210230646A1 (en) 2021-07-29
WO2013022881A1 (en) 2013-02-14
MX2014001571A (es) 2014-09-08

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