MX354214B - Sal de tipo camsilato. - Google Patents

Sal de tipo camsilato.

Info

Publication number
MX354214B
MX354214B MX2014014709A MX2014014709A MX354214B MX 354214 B MX354214 B MX 354214B MX 2014014709 A MX2014014709 A MX 2014014709A MX 2014014709 A MX2014014709 A MX 2014014709A MX 354214 B MX354214 B MX 354214B
Authority
MX
Mexico
Prior art keywords
dementia
salt
disease
camsylate salt
senile dementia
Prior art date
Application number
MX2014014709A
Other languages
English (en)
Spanish (es)
Other versions
MX2014014709A (es
Inventor
Robert Stewart Craig
Hans Bohlin Martin
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of MX2014014709A publication Critical patent/MX2014014709A/es
Publication of MX354214B publication Critical patent/MX354214B/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
MX2014014709A 2012-06-21 2013-06-20 Sal de tipo camsilato. MX354214B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261662592P 2012-06-21 2012-06-21
PCT/GB2013/051606 WO2013190302A1 (en) 2012-06-21 2013-06-20 Camsylate salt

Publications (2)

Publication Number Publication Date
MX2014014709A MX2014014709A (es) 2015-03-04
MX354214B true MX354214B (es) 2018-02-19

Family

ID=48746084

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014014709A MX354214B (es) 2012-06-21 2013-06-20 Sal de tipo camsilato.

Country Status (42)

Country Link
US (1) US10548882B2 (https=)
EP (2) EP2864316B1 (https=)
JP (2) JP2015520221A (https=)
KR (1) KR102123708B1 (https=)
CN (2) CN106279102A (https=)
AP (2) AP2017009693A0 (https=)
AR (2) AR091495A1 (https=)
AU (2) AU2013279109B2 (https=)
BR (2) BR112014031531B1 (https=)
CA (1) CA2875589C (https=)
CL (1) CL2014003374A1 (https=)
CO (1) CO7151486A2 (https=)
CR (2) CR20140571A (https=)
CY (1) CY1119505T1 (https=)
DK (1) DK2864316T3 (https=)
DO (1) DOP2014000268A (https=)
EC (1) ECSP14032215A (https=)
ES (1) ES2618939T3 (https=)
HR (1) HRP20170359T1 (https=)
HU (1) HUE033376T2 (https=)
IL (1) IL236131A0 (https=)
IN (1) IN2014DN10088A (https=)
LT (1) LT2864316T (https=)
MA (2) MA39259B1 (https=)
ME (1) ME02633B (https=)
MX (1) MX354214B (https=)
NI (1) NI201400146A (https=)
NZ (2) NZ727045A (https=)
PE (1) PE20150670A1 (https=)
PH (2) PH12014502803A1 (https=)
PL (1) PL2864316T3 (https=)
PT (1) PT2864316T (https=)
RS (1) RS55815B1 (https=)
RU (1) RU2638175C2 (https=)
SG (1) SG11201407934UA (https=)
SI (1) SI2864316T1 (https=)
SM (1) SMT201700142T1 (https=)
TN (1) TN2014000491A1 (https=)
TW (2) TWI588140B (https=)
UA (1) UA114196C2 (https=)
WO (1) WO2013190302A1 (https=)
ZA (1) ZA201500408B (https=)

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US8415483B2 (en) 2010-12-22 2013-04-09 Astrazeneca Ab Compounds and their use as BACE inhibitors
EP2780321B1 (en) 2011-10-10 2015-12-30 Astrazeneca AB Mono-fluoro beta-secretase inhibitors
US9000185B2 (en) 2012-06-20 2015-04-07 Astrazeneca Ab Cycloalkyl ether compounds and their use as BACE inhibitors
US9000184B2 (en) 2012-06-20 2015-04-07 Astrazeneca Ab Cyclohexane-1,2′-naphthalene-1′,2″-imidazol compounds and their use as BACE inhibitors
US9000182B2 (en) 2012-06-20 2015-04-07 Astrazeneca Ab 2H-imidazol-4-amine compounds and their use as BACE inhibitors
US9000183B2 (en) 2012-06-20 2015-04-07 Astrazeneca Ab Cyclohexane-1,2′-indene-1′,2″-imidazol compounds and their use as BACE inhibitors
TW201629025A (zh) 2014-10-07 2016-08-16 阿斯特捷利康公司 化合物及其作為bace抑制劑之用途
JP6546410B2 (ja) * 2015-02-23 2019-07-17 ローム株式会社 電力供給装置、acアダプタ、acチャージャ、電子機器および電力供給システム
US20190262327A1 (en) 2016-03-15 2019-08-29 Astrazeneca Ab Combination of a bace inhibitor and an antibody or antigen-binding fragment for the treatment of a disorder associated with the accumulation of amyloid beta
AR107783A1 (es) 2016-03-15 2018-06-06 Lilly Co Eli Terapia de combinación
JP2022525157A (ja) * 2019-03-14 2022-05-11 アストラゼネカ・アクチエボラーグ 体重減少のためのラナベセスタット

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MX2007016180A (es) 2005-06-14 2008-03-07 Schering Corp Inhibidores de aspartil proteasas.
JP2009520686A (ja) 2005-11-21 2009-05-28 アストラゼネカ・アクチエボラーグ 新規な2−アミノ−イミダゾール−4−オン化合物並びに認知障害、アルツハイマー病、神経変性及び認知症の治療に使用する医薬の製造におけるその使用
TW200734311A (en) 2005-11-21 2007-09-16 Astrazeneca Ab New compounds
CA2633992A1 (en) 2005-12-21 2007-07-05 Boehringer Ingelheim International Gmbh Pyrimidine derivatives useful as inhibitors of pkc-theta
WO2007100536A1 (en) 2006-02-24 2007-09-07 Wyeth DIHYDROSPIRO[DIBENZO[A,D][7]ANNULENE-5,4'-IMIDAZOL] COMPOUNDS FOR THE INHIBITION OF β-SECRETASE
KR20090015967A (ko) 2006-06-12 2009-02-12 쉐링 코포레이션 헤테로사이클릭 아스파르틸 프로테아제 억제제
WO2008076044A1 (en) 2006-12-20 2008-06-26 Astrazeneca Ab Novel 2-amino-5, 5-diaryl-imidazol-4-ones
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TW201105650A (en) 2009-07-02 2011-02-16 Astrazeneca Ab New compounds
CN102812005B (zh) 2010-02-24 2014-12-10 生命医药公司 β-分泌酶抑制剂
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US8415483B2 (en) * 2010-12-22 2013-04-09 Astrazeneca Ab Compounds and their use as BACE inhibitors
EP2780321B1 (en) 2011-10-10 2015-12-30 Astrazeneca AB Mono-fluoro beta-secretase inhibitors
US9000182B2 (en) 2012-06-20 2015-04-07 Astrazeneca Ab 2H-imidazol-4-amine compounds and their use as BACE inhibitors
US9000184B2 (en) 2012-06-20 2015-04-07 Astrazeneca Ab Cyclohexane-1,2′-naphthalene-1′,2″-imidazol compounds and their use as BACE inhibitors
US9000185B2 (en) 2012-06-20 2015-04-07 Astrazeneca Ab Cycloalkyl ether compounds and their use as BACE inhibitors
US9000183B2 (en) 2012-06-20 2015-04-07 Astrazeneca Ab Cyclohexane-1,2′-indene-1′,2″-imidazol compounds and their use as BACE inhibitors

Also Published As

Publication number Publication date
CR20160202A (es) 2016-07-26
CL2014003374A1 (es) 2015-02-27
AP2017009693A0 (en) 2017-01-31
TW201730177A (zh) 2017-09-01
SMT201700142T1 (it) 2017-05-08
ECSP14032215A (es) 2015-12-31
ME02633B (me) 2017-06-20
EP2864316B1 (en) 2016-12-14
MX2014014709A (es) 2015-03-04
PL2864316T3 (pl) 2017-09-29
CN106279102A (zh) 2017-01-04
RS55815B1 (sr) 2017-08-31
JP6509393B2 (ja) 2019-05-08
PH12016500498A1 (en) 2017-04-10
AU2013279109B2 (en) 2017-08-31
ES2618939T3 (es) 2017-06-22
HRP20170359T1 (hr) 2017-05-05
RU2014148305A (ru) 2016-08-10
WO2013190302A1 (en) 2013-12-27
BR122016014302A2 (pt) 2019-08-27
MA39259A1 (fr) 2017-12-29
PH12014502803B1 (en) 2015-02-23
PT2864316T (pt) 2017-02-24
BR122016014302B1 (pt) 2022-08-23
AR105176A2 (es) 2017-09-13
AU2013279109A1 (en) 2015-01-15
CA2875589A1 (en) 2013-12-27
RU2638175C2 (ru) 2017-12-12
CO7151486A2 (es) 2014-12-29
NZ727045A (en) 2018-06-29
HUE033376T2 (en) 2017-11-28
CN104411697A (zh) 2015-03-11
PH12014502803A1 (en) 2015-02-23
UA114196C2 (uk) 2017-05-10
BR112014031531B1 (pt) 2022-08-02
TWI639591B (zh) 2018-11-01
US10548882B2 (en) 2020-02-04
TN2014000491A1 (en) 2016-03-30
NI201400146A (es) 2016-09-21
AR091495A1 (es) 2015-02-11
CR20140571A (es) 2015-02-04
AP2014008137A0 (en) 2014-12-31
ZA201500408B (en) 2016-10-26
US20140031379A1 (en) 2014-01-30
KR102123708B1 (ko) 2020-06-16
KR20150023388A (ko) 2015-03-05
MA39259B1 (fr) 2018-09-28
IN2014DN10088A (https=) 2015-08-21
BR112014031531A2 (pt) 2017-06-27
NZ702742A (en) 2016-12-23
TW201406745A (zh) 2014-02-16
MA37666B1 (fr) 2016-12-30
AU2017254965A1 (en) 2017-11-23
HK1206349A1 (en) 2016-01-08
JP2018104448A (ja) 2018-07-05
EP3064494A1 (en) 2016-09-07
CY1119505T1 (el) 2018-03-07
TWI588140B (zh) 2017-06-21
MA37666A1 (fr) 2016-04-29
JP2015520221A (ja) 2015-07-16
EP2864316A1 (en) 2015-04-29
SI2864316T1 (sl) 2017-04-26
LT2864316T (lt) 2017-03-27
IL236131A0 (en) 2015-02-01
CN104411697B (zh) 2016-08-10
SG11201407934UA (en) 2015-01-29
DK2864316T3 (en) 2017-03-20
CA2875589C (en) 2020-08-25
DOP2014000268A (es) 2015-04-15
AU2017254965B2 (en) 2019-05-09
PE20150670A1 (es) 2015-06-03

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