MX352596B - Composicion farmaceutica que comprende (1r,4r)-6´-fluoro-n,n-dimet il-4-fenil-4´,9´-dihidro-3´h-espiro[ciclohexan-1,1´-piran-[3,4,b] indol]-4-amina y paracetamol o propacetamol. - Google Patents

Composicion farmaceutica que comprende (1r,4r)-6´-fluoro-n,n-dimet il-4-fenil-4´,9´-dihidro-3´h-espiro[ciclohexan-1,1´-piran-[3,4,b] indol]-4-amina y paracetamol o propacetamol.

Info

Publication number
MX352596B
MX352596B MX2014012723A MX2014012723A MX352596B MX 352596 B MX352596 B MX 352596B MX 2014012723 A MX2014012723 A MX 2014012723A MX 2014012723 A MX2014012723 A MX 2014012723A MX 352596 B MX352596 B MX 352596B
Authority
MX
Mexico
Prior art keywords
propacetamol
pyrano
paracetamol
indol
spiro
Prior art date
Application number
MX2014012723A
Other languages
English (en)
Spanish (es)
Other versions
MX2014012723A (es
Inventor
Linz Klaus
Schiene Klaus
Frosch Stefanie
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of MX2014012723A publication Critical patent/MX2014012723A/es
Publication of MX352596B publication Critical patent/MX352596B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/223—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of alpha-aminoacids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
MX2014012723A 2012-05-18 2013-05-16 Composicion farmaceutica que comprende (1r,4r)-6´-fluoro-n,n-dimet il-4-fenil-4´,9´-dihidro-3´h-espiro[ciclohexan-1,1´-piran-[3,4,b] indol]-4-amina y paracetamol o propacetamol. MX352596B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12003897 2012-05-18
PCT/EP2013/001468 WO2013170969A1 (en) 2012-05-18 2013-05-16 Pharmaceutical composition comprising (1r,4r)-6'-fluoro-n,n-dimethyl-4-phenyl-4',9'-dihydro-3'h-spiro[cyclohexane-1,1'-pyrano'[3,4,b]indol]-4-amine and paracetamol or propacetamol

Publications (2)

Publication Number Publication Date
MX2014012723A MX2014012723A (es) 2015-01-15
MX352596B true MX352596B (es) 2017-11-30

Family

ID=48468208

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014012723A MX352596B (es) 2012-05-18 2013-05-16 Composicion farmaceutica que comprende (1r,4r)-6´-fluoro-n,n-dimet il-4-fenil-4´,9´-dihidro-3´h-espiro[ciclohexan-1,1´-piran-[3,4,b] indol]-4-amina y paracetamol o propacetamol.

Country Status (22)

Country Link
US (3) US20130310435A1 (enExample)
EP (1) EP2849740B1 (enExample)
JP (1) JP6116676B2 (enExample)
CN (2) CN108524498A (enExample)
AU (1) AU2013262075B2 (enExample)
BR (1) BR112014028561A2 (enExample)
CA (1) CA2873644A1 (enExample)
CY (1) CY1119610T1 (enExample)
DK (1) DK2849740T3 (enExample)
EA (1) EA026949B1 (enExample)
ES (1) ES2650441T3 (enExample)
HR (1) HRP20171438T1 (enExample)
HU (1) HUE034676T2 (enExample)
IL (1) IL235651B (enExample)
LT (1) LT2849740T (enExample)
MX (1) MX352596B (enExample)
NO (1) NO2849740T3 (enExample)
PL (1) PL2849740T3 (enExample)
PT (1) PT2849740T (enExample)
RS (1) RS56617B1 (enExample)
SI (1) SI2849740T1 (enExample)
WO (1) WO2013170969A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107427493A (zh) 2015-01-23 2017-12-01 格吕伦塔尔有限公司 用于治疗肝功能受损和/或肾功能受损的受试者的疼痛的Cebranopadol
MX2018010367A (es) 2016-02-29 2018-12-10 Guenenthal Gmbh Titulacion de cebranopadol.
WO2026161433A1 (en) * 2025-01-21 2026-07-30 Adneuris Therapeutics, Inc. Cebranopadol useful for alleviating pain
WO2026161842A1 (en) * 2025-01-27 2026-07-30 Adneuris Therapeutics, Inc. Cebranopadol useful for treating pain

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Also Published As

Publication number Publication date
EA026949B1 (ru) 2017-06-30
US20190350884A1 (en) 2019-11-21
RS56617B1 (sr) 2018-02-28
HRP20171438T1 (hr) 2017-11-03
JP2015516449A (ja) 2015-06-11
AU2013262075B2 (en) 2017-10-26
WO2013170969A1 (en) 2013-11-21
PT2849740T (pt) 2017-12-13
EP2849740B1 (en) 2017-09-13
BR112014028561A2 (pt) 2017-07-25
CY1119610T1 (el) 2018-04-04
MX2014012723A (es) 2015-01-15
ES2650441T3 (es) 2018-01-18
DK2849740T3 (da) 2017-11-20
JP6116676B2 (ja) 2017-04-19
US20180092867A1 (en) 2018-04-05
HK1204940A1 (en) 2015-12-11
US11311504B2 (en) 2022-04-26
HUE034676T2 (hu) 2018-02-28
CN104302282A (zh) 2015-01-21
LT2849740T (lt) 2017-12-27
PL2849740T3 (pl) 2018-03-30
EA201401272A1 (ru) 2015-05-29
SI2849740T1 (en) 2018-01-31
NO2849740T3 (enExample) 2018-02-10
IL235651B (en) 2018-08-30
AU2013262075A1 (en) 2015-01-22
IL235651A0 (en) 2015-01-29
CA2873644A1 (en) 2013-11-21
EP2849740A1 (en) 2015-03-25
US20130310435A1 (en) 2013-11-21
CN108524498A (zh) 2018-09-14

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