CA2873644A1 - Pharmaceutical composition comprising (1r,4r)-6'-fluoro-n,n-dimethyl-4-phenyl-4',9'-dihydro-3'h-spiro[cyclohexane-1,1'-pyrano-[3,4,b]indol]-4-amine and paracetamol or propacetamol - Google Patents
Pharmaceutical composition comprising (1r,4r)-6'-fluoro-n,n-dimethyl-4-phenyl-4',9'-dihydro-3'h-spiro[cyclohexane-1,1'-pyrano-[3,4,b]indol]-4-amine and paracetamol or propacetamol Download PDFInfo
- Publication number
- CA2873644A1 CA2873644A1 CA2873644A CA2873644A CA2873644A1 CA 2873644 A1 CA2873644 A1 CA 2873644A1 CA 2873644 A CA2873644 A CA 2873644A CA 2873644 A CA2873644 A CA 2873644A CA 2873644 A1 CA2873644 A1 CA 2873644A1
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- CA
- Canada
- Prior art keywords
- active ingredient
- pharmacologically active
- dosage form
- pharmaceutical dosage
- pain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/223—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of alpha-aminoacids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Emergency Medicine (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12003897.1 | 2012-05-18 | ||
| EP12003897 | 2012-05-18 | ||
| PCT/EP2013/001468 WO2013170969A1 (en) | 2012-05-18 | 2013-05-16 | Pharmaceutical composition comprising (1r,4r)-6'-fluoro-n,n-dimethyl-4-phenyl-4',9'-dihydro-3'h-spiro[cyclohexane-1,1'-pyrano'[3,4,b]indol]-4-amine and paracetamol or propacetamol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2873644A1 true CA2873644A1 (en) | 2013-11-21 |
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ID=48468208
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2873644A Abandoned CA2873644A1 (en) | 2012-05-18 | 2013-05-16 | Pharmaceutical composition comprising (1r,4r)-6'-fluoro-n,n-dimethyl-4-phenyl-4',9'-dihydro-3'h-spiro[cyclohexane-1,1'-pyrano-[3,4,b]indol]-4-amine and paracetamol or propacetamol |
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|---|---|
| US (3) | US20130310435A1 (enExample) |
| EP (1) | EP2849740B1 (enExample) |
| JP (1) | JP6116676B2 (enExample) |
| CN (2) | CN108524498A (enExample) |
| AU (1) | AU2013262075B2 (enExample) |
| BR (1) | BR112014028561A2 (enExample) |
| CA (1) | CA2873644A1 (enExample) |
| CY (1) | CY1119610T1 (enExample) |
| DK (1) | DK2849740T3 (enExample) |
| EA (1) | EA026949B1 (enExample) |
| ES (1) | ES2650441T3 (enExample) |
| HR (1) | HRP20171438T1 (enExample) |
| HU (1) | HUE034676T2 (enExample) |
| IL (1) | IL235651B (enExample) |
| LT (1) | LT2849740T (enExample) |
| MX (1) | MX352596B (enExample) |
| NO (1) | NO2849740T3 (enExample) |
| PL (1) | PL2849740T3 (enExample) |
| PT (1) | PT2849740T (enExample) |
| RS (1) | RS56617B1 (enExample) |
| SI (1) | SI2849740T1 (enExample) |
| WO (1) | WO2013170969A1 (enExample) |
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|---|---|---|---|---|
| EA201791662A1 (ru) | 2015-01-23 | 2017-12-29 | Грюненталь Гмбх | Цебранопадол для лечения от боли субъектов с нарушенной печеночной и/или нарушенной почечной функцией |
| JP7373904B2 (ja) | 2016-02-29 | 2023-11-06 | パーク・セラピューティクス・インコーポレイテッド | セブラノパドールの滴定 |
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| DE3273329D1 (en) | 1981-06-26 | 1986-10-23 | Upjohn Co | Analgesic process and composition |
| US4389393A (en) | 1982-03-26 | 1983-06-21 | Forest Laboratories, Inc. | Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose |
| US4404208A (en) | 1982-06-30 | 1983-09-13 | E. I. Du Pont De Nemours And Company | Analgesic mixture of nalbuphine and tiflamizole |
| IE55189B1 (en) | 1982-07-08 | 1990-06-20 | Wyeth John & Brother Ltd | Pharmaceutical compositions |
| US4765989A (en) | 1983-05-11 | 1988-08-23 | Alza Corporation | Osmotic device for administering certain drugs |
| US4612008A (en) | 1983-05-11 | 1986-09-16 | Alza Corporation | Osmotic device with dual thermodynamic activity |
| US4783337A (en) | 1983-05-11 | 1988-11-08 | Alza Corporation | Osmotic system comprising plurality of members for dispensing drug |
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2013
- 2013-05-13 US US13/892,969 patent/US20130310435A1/en not_active Abandoned
- 2013-05-16 ES ES13723674.1T patent/ES2650441T3/es active Active
- 2013-05-16 HU HUE13723674A patent/HUE034676T2/hu unknown
- 2013-05-16 CN CN201810706944.9A patent/CN108524498A/zh active Pending
- 2013-05-16 EP EP13723674.1A patent/EP2849740B1/en not_active Not-in-force
- 2013-05-16 WO PCT/EP2013/001468 patent/WO2013170969A1/en not_active Ceased
- 2013-05-16 JP JP2015511955A patent/JP6116676B2/ja active Active
- 2013-05-16 CA CA2873644A patent/CA2873644A1/en not_active Abandoned
- 2013-05-16 DK DK13723674.1T patent/DK2849740T3/da active
- 2013-05-16 MX MX2014012723A patent/MX352596B/es active IP Right Grant
- 2013-05-16 AU AU2013262075A patent/AU2013262075B2/en not_active Ceased
- 2013-05-16 HR HRP20171438TT patent/HRP20171438T1/hr unknown
- 2013-05-16 PL PL13723674T patent/PL2849740T3/pl unknown
- 2013-05-16 PT PT137236741T patent/PT2849740T/pt unknown
- 2013-05-16 NO NO13723674A patent/NO2849740T3/no unknown
- 2013-05-16 EA EA201401272A patent/EA026949B1/ru not_active IP Right Cessation
- 2013-05-16 BR BR112014028561A patent/BR112014028561A2/pt not_active IP Right Cessation
- 2013-05-16 LT LTEP13723674.1T patent/LT2849740T/lt unknown
- 2013-05-16 CN CN201380025683.XA patent/CN104302282A/zh active Pending
- 2013-05-16 SI SI201330870T patent/SI2849740T1/en unknown
- 2013-05-16 RS RS20171229A patent/RS56617B1/sr unknown
-
2014
- 2014-11-12 IL IL235651A patent/IL235651B/en active IP Right Grant
-
2017
- 2017-10-06 US US15/726,761 patent/US20180092867A1/en not_active Abandoned
- 2017-11-20 CY CY20171101212T patent/CY1119610T1/el unknown
-
2019
- 2019-07-03 US US16/502,651 patent/US11311504B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| LT2849740T (lt) | 2017-12-27 |
| CN108524498A (zh) | 2018-09-14 |
| HRP20171438T1 (hr) | 2017-11-03 |
| IL235651A0 (en) | 2015-01-29 |
| NO2849740T3 (enExample) | 2018-02-10 |
| AU2013262075A1 (en) | 2015-01-22 |
| US20190350884A1 (en) | 2019-11-21 |
| MX352596B (es) | 2017-11-30 |
| EP2849740A1 (en) | 2015-03-25 |
| JP2015516449A (ja) | 2015-06-11 |
| WO2013170969A1 (en) | 2013-11-21 |
| PL2849740T3 (pl) | 2018-03-30 |
| US11311504B2 (en) | 2022-04-26 |
| HK1204940A1 (en) | 2015-12-11 |
| US20180092867A1 (en) | 2018-04-05 |
| RS56617B1 (sr) | 2018-02-28 |
| AU2013262075B2 (en) | 2017-10-26 |
| DK2849740T3 (da) | 2017-11-20 |
| HUE034676T2 (hu) | 2018-02-28 |
| US20130310435A1 (en) | 2013-11-21 |
| PT2849740T (pt) | 2017-12-13 |
| CN104302282A (zh) | 2015-01-21 |
| IL235651B (en) | 2018-08-30 |
| EA201401272A1 (ru) | 2015-05-29 |
| BR112014028561A2 (pt) | 2017-07-25 |
| CY1119610T1 (el) | 2018-04-04 |
| EA026949B1 (ru) | 2017-06-30 |
| MX2014012723A (es) | 2015-01-15 |
| ES2650441T3 (es) | 2018-01-18 |
| EP2849740B1 (en) | 2017-09-13 |
| SI2849740T1 (en) | 2018-01-31 |
| JP6116676B2 (ja) | 2017-04-19 |
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| EEER | Examination request |
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| FZDE | Discontinued |
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| FZDE | Discontinued |
Effective date: 20210831 |