MX342712B - Macromolecula para el suministro de farmacos de proteina, polipeptido o peptido y un metodo de produccion para la misma, y una composicion de liberacion lenta para farmacos de proteina, polipeptido o peptido y un metodo de produccion para la misma. - Google Patents
Macromolecula para el suministro de farmacos de proteina, polipeptido o peptido y un metodo de produccion para la misma, y una composicion de liberacion lenta para farmacos de proteina, polipeptido o peptido y un metodo de produccion para la misma.Info
- Publication number
- MX342712B MX342712B MX2012007603A MX2012007603A MX342712B MX 342712 B MX342712 B MX 342712B MX 2012007603 A MX2012007603 A MX 2012007603A MX 2012007603 A MX2012007603 A MX 2012007603A MX 342712 B MX342712 B MX 342712B
- Authority
- MX
- Mexico
- Prior art keywords
- same
- polypeptide
- production method
- protein
- peptide drugs
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/465—Preparation of carboxylic acid esters by oligomerisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
- C07C69/675—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids of saturated hydroxy-carboxylic acids
- C07C69/68—Lactic acid esters
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
- C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/91—Polymers modified by chemical after-treatment
- C08G63/912—Polymers modified by chemical after-treatment derived from hydroxycarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/20—Compounding polymers with additives, e.g. colouring
- C08J3/205—Compounding polymers with additives, e.g. colouring in the presence of a continuous liquid phase
- C08J3/21—Compounding polymers with additives, e.g. colouring in the presence of a continuous liquid phase the polymer being premixed with a liquid phase
- C08J3/215—Compounding polymers with additives, e.g. colouring in the presence of a continuous liquid phase the polymer being premixed with a liquid phase at least one additive being also premixed with a liquid phase
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2367/00—Characterised by the use of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Derivatives of such polymers
- C08J2367/04—Polyesters derived from hydroxy carboxylic acids, e.g. lactones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Inorganic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Polyesters Or Polycarbonates (AREA)
- Biological Depolymerization Polymers (AREA)
- Peptides Or Proteins (AREA)
Abstract
La presente invención se refiere a una macromolécula para suministrar fármacos de proteína, polipéptido o péptido y a un método de producción para la misma, así como también a una composición de liberación lenta para fármacos de proteína, polipéptido o péptido que comprende la misma, y más específicamente se relaciona a un compuesto derivado de ácido poliláctico de la fórmula química 1 de la cual el peso molecular promedio en número no es más que 7,000 daltons y a un. Método de producción para el mismo, así como a una composición de liberación lenta para fármacos de proteína, polipéptido péptido que utilizan el mismo y a un método de producción para el mismo.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR20090132861 | 2009-12-29 | ||
PCT/KR2010/009421 WO2011081406A2 (ko) | 2009-12-29 | 2010-12-28 | 단백질, 폴리펩타이드 또는 펩타이드 약물 전달용 고분자 및 그 제조방법, 및 단백질, 폴리펩타이드 또는 펩타이드 약물의 서방형 조성물 및 그 제조 방법 |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2012007603A MX2012007603A (es) | 2012-08-01 |
MX342712B true MX342712B (es) | 2016-10-10 |
Family
ID=44227011
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2012007603A MX342712B (es) | 2009-12-29 | 2010-12-28 | Macromolecula para el suministro de farmacos de proteina, polipeptido o peptido y un metodo de produccion para la misma, y una composicion de liberacion lenta para farmacos de proteina, polipeptido o peptido y un metodo de produccion para la misma. |
Country Status (12)
Country | Link |
---|---|
US (1) | US9603931B2 (es) |
EP (1) | EP2520600B1 (es) |
JP (1) | JP5597724B2 (es) |
KR (1) | KR101224004B1 (es) |
CN (1) | CN102741317B (es) |
AU (1) | AU2010339080B2 (es) |
BR (1) | BR112012015977B1 (es) |
CA (1) | CA2784990C (es) |
ES (1) | ES2628137T3 (es) |
MX (1) | MX342712B (es) |
NZ (1) | NZ600775A (es) |
WO (1) | WO2011081406A2 (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101424163B1 (ko) * | 2010-12-24 | 2014-08-01 | 주식회사 삼양바이오팜 | 수난용성 약물 함유 서방성 마이크로입자 및 그 제조방법 |
KR101467275B1 (ko) * | 2011-12-19 | 2014-12-02 | 주식회사 삼양바이오팜 | 분산성이 향상된 생분해성 고분자 미립자의 조성물 및 그 제조방법 |
KR101547634B1 (ko) | 2013-06-21 | 2015-08-26 | 가톨릭대학교 산학협력단 | 약물 전달용 환원성 폴리뉴클레오타이드 고분자 및 이의 제조방법 |
JP6139029B2 (ja) * | 2013-06-21 | 2017-05-31 | ザ カトリック ユニバーシティ オブ コリア インダストリー−アカデミック コーオペレイション ファウンデーション | 薬物送達用還元性または非還元性ポリヌクレオチド高分子及びその製造方法 |
KR101547633B1 (ko) | 2013-06-21 | 2015-08-26 | 가톨릭대학교 산학협력단 | 약물 전달용 비환원성 폴리뉴클레오타이드 고분자 및 이의 제조방법 |
ZA201407536B (en) * | 2013-10-21 | 2017-09-27 | Ems Sa | Parenteral pharmaceutical composition containing cosyntropin |
JP6637484B2 (ja) * | 2014-08-07 | 2020-01-29 | ザ ジェネラル ホスピタル コーポレイション | 血小板を標的とするマイクロ流体細胞単離 |
US10160896B2 (en) | 2015-04-27 | 2018-12-25 | Halliburton Energy Services, Inc. | Delayed-release additives in a degradable matrix |
KR101547636B1 (ko) | 2015-07-20 | 2015-08-27 | 가톨릭대학교 산학협력단 | 환원성 폴리뉴클레오타이드 고분자를 포함하는 비바이러스성 약물전달용 조성물 |
KR101547635B1 (ko) | 2015-07-20 | 2015-08-27 | 가톨릭대학교 산학협력단 | 비환원성 폴리뉴클레오타이드 고분자를 포함하는 비바이러스성 약물전달용 조성물 |
CN108660614B (zh) * | 2018-05-22 | 2020-04-03 | 西南交通大学 | 一种聚乳酸多孔薄膜及其制备方法 |
EP4442728A1 (en) * | 2021-11-30 | 2024-10-09 | Nisshinbo Holdings Inc. | Marine biodegradable polymer compound, marine biodegradation promoter, and marine biodegradable resin composition |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
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BE556559A (es) * | 1956-04-13 | |||
JPS62135521A (ja) * | 1985-12-10 | 1987-06-18 | Daicel Chem Ind Ltd | 末端にカルボキシル基を有するポリカプロラクトン |
JPS6369825A (ja) * | 1986-09-11 | 1988-03-29 | Mitsui Toatsu Chem Inc | ブロツク共重合体及びその製造方法 |
US5196502A (en) * | 1991-11-05 | 1993-03-23 | Eastman Kodak Company | Method for the preparation of multiply-branched aromatic polyesters |
HU220137B (hu) | 1993-01-06 | 2001-11-28 | Kinerton Ltd. | Biológiailag lebontható poliészterek és biológiailag aktív polipeptidek ionos molekuláris konjugátumai, eljárás ezek előállítására és eljárás mikrorészecskék előállítására |
US6221958B1 (en) * | 1993-01-06 | 2001-04-24 | Societe De Conseils De Recherches Et D'applications Scientifiques, Sas | Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides |
JP3287425B2 (ja) * | 1993-02-04 | 2002-06-04 | 東洋紡績株式会社 | 水酸基末端をエステル封鎖したポリ乳酸およびその製造法 |
KR0141431B1 (ko) | 1994-05-17 | 1998-07-01 | 김상웅 | 생분해성 하이드로겔 고분자 |
JPH0859642A (ja) | 1994-08-22 | 1996-03-05 | Mitsubishi Chem Corp | 3,4−アルキレン−1,3,4−チアジアゾリジン−2−オン類の製造方法 |
US5668288A (en) | 1996-04-16 | 1997-09-16 | Depuy Orthopaedics, Inc. | Polyester ionomers for implant fabrication |
IE960308A1 (en) | 1996-04-23 | 1997-11-05 | Kinerton Ltd | Sustained release ionic conjugate |
DK0946169T3 (da) * | 1996-12-20 | 2003-04-22 | Takeda Chemical Industries Ltd | Fremgangsmåde til fremstilling af et præparat med vedvarende frigivelse |
JPH1121343A (ja) * | 1997-07-01 | 1999-01-26 | Mitsui Chem Inc | ポリヒドロキシカルボン酸の製造方法 |
JPH1160928A (ja) * | 1997-08-27 | 1999-03-05 | Nishikawa Rubber Co Ltd | ポリヒドロキシカルボン酸樹脂組成物およびその製造方法 |
US6541033B1 (en) | 1998-06-30 | 2003-04-01 | Amgen Inc. | Thermosensitive biodegradable hydrogels for sustained delivery of leptin |
EP1448707B1 (en) * | 2001-10-18 | 2007-08-22 | Samyang Corporation | Polymeric micelle composition with improved stability |
JP2005505675A (ja) | 2001-10-18 | 2005-02-24 | サムヤン コーポレイション | 高分子ミセルを形成するpH応答性生分解性ポリ乳酸誘導体及び難溶性薬物伝達体への当該誘導体の使用 |
US20080260850A1 (en) * | 2004-05-06 | 2008-10-23 | Samyang Corporation | Delivery System For Bioactive Agents on the Basis of a Polymeric Drug Carrier Comprising an Amphiphilic Block Polymer and a Polylacticacid Derivative |
US7655735B2 (en) * | 2004-08-02 | 2010-02-02 | Samyang Corporation | Biodegradable multi-block polymeric composition capable of sol-gel transition and pharmaceutical composition comprising the same |
EP1647567A1 (en) * | 2004-10-15 | 2006-04-19 | SOLVAY (Société Anonyme) | Methods of producing amine-terminated caprolactone polymers and uses of the produced polymers |
CN101104706A (zh) * | 2007-08-06 | 2008-01-16 | 四川大学 | 聚乳酸及其衍生物的电子束辐射改性方法 |
KR101024742B1 (ko) | 2007-12-31 | 2011-03-24 | 주식회사 삼양사 | 탁산 함유 양친성 블록 공중합체 미셀 조성물 및 그 제조방법 |
-
2010
- 2010-12-23 KR KR20100133192A patent/KR101224004B1/ko active IP Right Grant
- 2010-12-28 JP JP2012547015A patent/JP5597724B2/ja active Active
- 2010-12-28 BR BR112012015977-1A patent/BR112012015977B1/pt not_active IP Right Cessation
- 2010-12-28 WO PCT/KR2010/009421 patent/WO2011081406A2/ko active Application Filing
- 2010-12-28 EP EP10841238.8A patent/EP2520600B1/en active Active
- 2010-12-28 US US13/519,729 patent/US9603931B2/en active Active
- 2010-12-28 AU AU2010339080A patent/AU2010339080B2/en not_active Ceased
- 2010-12-28 MX MX2012007603A patent/MX342712B/es active IP Right Grant
- 2010-12-28 CN CN201080063259.0A patent/CN102741317B/zh active Active
- 2010-12-28 ES ES10841238.8T patent/ES2628137T3/es active Active
- 2010-12-28 CA CA2784990A patent/CA2784990C/en not_active Expired - Fee Related
- 2010-12-28 NZ NZ600775A patent/NZ600775A/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
WO2011081406A2 (ko) | 2011-07-07 |
ES2628137T3 (es) | 2017-08-01 |
US20130274188A1 (en) | 2013-10-17 |
JP5597724B2 (ja) | 2014-10-01 |
MX2012007603A (es) | 2012-08-01 |
BR112012015977B1 (pt) | 2020-10-06 |
US9603931B2 (en) | 2017-03-28 |
EP2520600A2 (en) | 2012-11-07 |
EP2520600A4 (en) | 2014-01-08 |
AU2010339080A1 (en) | 2012-07-19 |
AU2010339080B2 (en) | 2015-09-17 |
NZ600775A (en) | 2015-01-30 |
AU2010339080A9 (en) | 2015-09-17 |
EP2520600B1 (en) | 2017-03-29 |
BR112012015977A2 (pt) | 2018-05-29 |
CA2784990C (en) | 2015-03-31 |
CN102741317B (zh) | 2015-01-07 |
KR20110076783A (ko) | 2011-07-06 |
KR101224004B1 (ko) | 2013-01-22 |
CA2784990A1 (en) | 2011-07-07 |
WO2011081406A3 (ko) | 2011-12-01 |
CN102741317A (zh) | 2012-10-17 |
JP2013515833A (ja) | 2013-05-09 |
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