MX337290B - Anticuerpos anti igg reactivos no cruzados. - Google Patents

Anticuerpos anti igg reactivos no cruzados.

Info

Publication number
MX337290B
MX337290B MX2012003825A MX2012003825A MX337290B MX 337290 B MX337290 B MX 337290B MX 2012003825 A MX2012003825 A MX 2012003825A MX 2012003825 A MX2012003825 A MX 2012003825A MX 337290 B MX337290 B MX 337290B
Authority
MX
Mexico
Prior art keywords
cell lines
cross
antibodies
dsm
igg antibodies
Prior art date
Application number
MX2012003825A
Other languages
English (en)
Other versions
MX2012003825A (es
Inventor
Kay-Gunnar Stubenrauch
Rudolf Vogel
Uwe Wessels
Ulrich Essig
Stefan Klostermann
Frank Kowalewsky
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MX2012003825A publication Critical patent/MX2012003825A/es
Publication of MX337290B publication Critical patent/MX337290B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La presente invención se refiere a las líneas celulares DSM ACC3006, DSM ACC3007 y DSM ACC3008, así como los anticuerpos obtenidos de las líneas celulares y el uso de un anticuerpo obtenido de las líneas celulares en una inmunoprueba. También se describen anticuerpos que unen a IgG de humano o chimpancé y que no unen a IgG canina y de tití, y anticuerpos que unen específicamente a una IgG1 que comprende un dominio constante de cadena ligera kappa.
MX2012003825A 2009-10-19 2010-10-18 Anticuerpos anti igg reactivos no cruzados. MX337290B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09013144 2009-10-19
PCT/EP2010/065617 WO2011048043A1 (en) 2009-10-19 2010-10-18 NON-CROSS-REACTIVE ANTI IgG ANTIBODIES

Publications (2)

Publication Number Publication Date
MX2012003825A MX2012003825A (es) 2012-05-08
MX337290B true MX337290B (es) 2016-02-24

Family

ID=41834476

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012003825A MX337290B (es) 2009-10-19 2010-10-18 Anticuerpos anti igg reactivos no cruzados.

Country Status (13)

Country Link
US (1) US9957331B2 (es)
EP (1) EP2491397B1 (es)
JP (2) JP5715634B2 (es)
KR (1) KR101536388B1 (es)
CN (2) CN105624118B (es)
AU (1) AU2010309931B2 (es)
BR (1) BR112012005668A2 (es)
CA (1) CA2776576C (es)
ES (1) ES2628839T3 (es)
IL (1) IL217934A (es)
MX (1) MX337290B (es)
SG (1) SG2014014823A (es)
WO (1) WO2011048043A1 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG2014014823A (en) 2009-10-19 2014-07-30 Hoffmann La Roche Non-cross-reactive anti igg antibodies
WO2012022682A1 (en) * 2010-08-17 2012-02-23 F. Hoffmann-La Roche Ag Anti-human igg1 antibody
MX349661B (es) * 2012-02-01 2017-08-08 Hoffmann La Roche Metodo para la deteccion de una molecula de union de un enlazador multiespecifico.
WO2014147101A1 (en) * 2013-03-20 2014-09-25 F. Hoffmann-La Roche Ag Specific detection of rat antibodies in mouse serum
KR101654890B1 (ko) * 2013-07-10 2016-09-07 한국과학기술원 면역글로불린 g에 대한 리피바디 및 그 용도
WO2017072210A1 (en) 2015-10-29 2017-05-04 F. Hoffmann-La Roche Ag Anti-variant fc-region antibodies and methods of use
WO2017082214A1 (ja) * 2015-11-09 2017-05-18 国立大学法人京都工芸繊維大学 単鎖抗体のスクリーニング方法及び単鎖抗体
JP6889160B2 (ja) * 2015-12-16 2021-06-18 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ ３段階酸解離酵素結合免疫吸着（ｔａｄｅｌｉｓ）アッセイ法
CN109280644B (zh) * 2018-09-04 2023-02-17 四川安可瑞新材料技术有限公司 抗人IgG单克隆抗体、其杂交瘤细胞株及应用
CN109266620B (zh) * 2018-09-04 2023-01-10 四川安可瑞新材料技术有限公司 抗人IgG单克隆抗体、其杂交瘤细胞株及应用
CN109112113B (zh) * 2018-09-05 2023-01-10 四川安可瑞新材料技术有限公司 抗人IgG的单克隆抗体、杂交瘤细胞株、试剂盒及其应用
CN109082413B (zh) * 2018-09-18 2023-01-10 四川安可瑞新材料技术有限公司 抗人IgG单克隆抗体、其杂交瘤细胞株及应用
CN109112114B (zh) * 2018-09-18 2023-02-17 四川安可瑞新材料技术有限公司 抗人IgG单克隆抗体、其杂交瘤细胞株及应用
CN110483643B (zh) * 2018-09-19 2021-06-08 深圳市雅为泓源生物科技有限公司 一种新型的抗体组合物、分离的核酸和制备方法
CN111190020B (zh) * 2020-01-20 2024-02-02 苏州药明康德新药开发有限公司 一种添加猴血清优化通用型生物分析的方法
CN112010981B (zh) * 2020-09-10 2021-05-18 南京妙迪生物科技有限公司 一种小鼠抗人IgG单克隆抗体
WO2023021055A1 (en) 2021-08-19 2023-02-23 F. Hoffmann-La Roche Ag Multivalent anti-variant fc-region antibodies and methods of use

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5202238A (en) 1987-10-27 1993-04-13 Oncogen Production of chimeric antibodies by homologous recombination
US5204244A (en) 1987-10-27 1993-04-20 Oncogen Production of chimeric antibodies by homologous recombination
US5332665A (en) * 1991-12-18 1994-07-26 The General Hospital Corporation Species specific, high affinity monoclonal antibodies
US5736137A (en) * 1992-11-13 1998-04-07 Idec Pharmaceuticals Corporation Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma
CN1180107A (zh) * 1996-06-18 1998-04-29 三井东压化学株式会社 一种单克隆抗体,能生产该抗体的细胞系及该抗体的用途
AR038568A1 (es) 2002-02-20 2005-01-19 Hoffmann La Roche Anticuerpos anti-a beta y su uso
TW200420554A (en) 2003-03-31 2004-10-16 Kyowa Hakko Kogyo Kk A intra-airway administrating preparation
JP4473257B2 (ja) 2003-04-02 2010-06-02 エフ．ホフマン−ラ ロシュ アーゲー インスリン様成長因子ｉ受容体に対する抗体及びその使用
AR046071A1 (es) 2003-07-10 2005-11-23 Hoffmann La Roche Anticuerpos contra el receptor i del factor de crecimiento de tipo insulinico y los usos de los mismos
AR045614A1 (es) 2003-09-10 2005-11-02 Hoffmann La Roche Anticuerpos contra el recepctor de la interleuquina- 1 y los usos de los mismos
PT1737891E (pt) 2004-04-13 2013-04-16 Hoffmann La Roche Anticorpos anti p-selectina
BRPI0519354B8 (pt) * 2004-12-23 2021-07-27 Hoffmann La Roche método para detecção de um anticorpo terapêutico e uso de um anticorpo
TW200902555A (en) 2005-01-03 2009-01-16 Hoffmann La Roche Antibodies against IL-13 receptor alpha 1 and uses thereof
CN101213450A (zh) * 2005-07-06 2008-07-02 霍夫曼-拉罗奇有限公司 不论存在或不存在相对应的治疗用抗体而检测靶抗原
ES2428876T3 (es) 2006-09-12 2013-11-12 F. Hoffmann-La Roche Ag Ensayo de anticuerpo antifármaco
CN101506659B (zh) * 2006-09-12 2012-12-12 弗·哈夫曼-拉罗切有限公司 抗药物抗体测定法
TWI434855B (zh) * 2006-11-21 2014-04-21 Hoffmann La Roche 結合物及其在免疫分析中作為參考標準之用途
SG2014014823A (en) 2009-10-19 2014-07-30 Hoffmann La Roche Non-cross-reactive anti igg antibodies
WO2012022682A1 (en) 2010-08-17 2012-02-23 F. Hoffmann-La Roche Ag Anti-human igg1 antibody

Also Published As

Publication number Publication date
EP2491397A1 (en) 2012-08-29
EP2491397B1 (en) 2017-04-19
KR20130026409A (ko) 2013-03-13
CN105624118A (zh) 2016-06-01
AU2010309931B2 (en) 2015-08-20
IL217934A (en) 2015-04-30
CN102656460A (zh) 2012-09-05
WO2011048043A1 (en) 2011-04-28
IL217934A0 (en) 2012-03-29
US9957331B2 (en) 2018-05-01
JP2015070847A (ja) 2015-04-16
JP5894248B2 (ja) 2016-03-23
KR101536388B1 (ko) 2015-07-22
MX2012003825A (es) 2012-05-08
SG2014014823A (en) 2014-07-30
JP2013508700A (ja) 2013-03-07
CN105624118B (zh) 2019-08-13
CN102656460B (zh) 2016-03-02
AU2010309931A1 (en) 2012-03-01
BR112012005668A2 (pt) 2020-10-13
CA2776576A1 (en) 2011-04-28
CA2776576C (en) 2018-01-02
JP5715634B2 (ja) 2015-05-13
ES2628839T3 (es) 2017-08-04
US20120208216A1 (en) 2012-08-16

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