MX23803A - Nuevos derivados de rodanina subtituidos con bencilo y procedimiento para su preparacion. - Google Patents

Nuevos derivados de rodanina subtituidos con bencilo y procedimiento para su preparacion.

Info

Publication number
MX23803A
MX23803A MX2380390A MX2380390A MX23803A MX 23803 A MX23803 A MX 23803A MX 2380390 A MX2380390 A MX 2380390A MX 2380390 A MX2380390 A MX 2380390A MX 23803 A MX23803 A MX 23803A
Authority
MX
Mexico
Prior art keywords
benzyl
rodanine
procedure
preparation
new
Prior art date
Application number
MX2380390A
Other languages
English (en)
Inventor
Jaswant Singh Gidda
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of MX23803A publication Critical patent/MX23803A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/14Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/36Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Eye Examination Apparatus (AREA)
  • Surgical Instruments (AREA)
  • Nonmetallic Welding Materials (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
MX2380390A 1989-12-21 1990-12-19 Nuevos derivados de rodanina subtituidos con bencilo y procedimiento para su preparacion. MX23803A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US45420389A 1989-12-21 1989-12-21

Publications (1)

Publication Number Publication Date
MX23803A true MX23803A (es) 1994-02-28

Family

ID=23803709

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2380390A MX23803A (es) 1989-12-21 1990-12-19 Nuevos derivados de rodanina subtituidos con bencilo y procedimiento para su preparacion.

Country Status (22)

Country Link
EP (1) EP0434394B1 (es)
JP (1) JP3036853B2 (es)
KR (1) KR0176243B1 (es)
CN (1) CN1029846C (es)
AT (1) ATE169294T1 (es)
AU (1) AU639734B2 (es)
CA (1) CA2032330C (es)
CY (1) CY2100B1 (es)
DE (1) DE69032537T2 (es)
DK (1) DK0434394T3 (es)
ES (1) ES2121748T3 (es)
FI (2) FI104251B (es)
HU (1) HU216732B (es)
IE (1) IE904633A1 (es)
IL (3) IL108962A (es)
MX (1) MX23803A (es)
NO (1) NO300458B1 (es)
NZ (1) NZ236472A (es)
PT (1) PT96198B (es)
RU (2) RU2036915C1 (es)
YU (1) YU240690A (es)
ZA (1) ZA9010041B (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU87339A1 (fr) * 1988-09-20 1990-04-06 Oreal Nouveaux derives de benzylidene-cyclanones,leur procede de preparation,leur utilisation en tant qu'agents anti-oxydants et comme filtres solaires,compositions cosmetiques et pharmaceutiques les contenant
US5143928A (en) * 1990-03-27 1992-09-01 Warner-Lambert Company 3,5-di-tertiarybutyl-4-hydroxyphenylmethylene derivatives of 2-substituted thiazolidinones, oxazolidinones, and imidazolidinones as antiinflammatory agents
ZA936492B (en) * 1992-09-10 1995-03-02 Lilly Co Eli Compounds useful as hypoglycemic agents and for treating Alzheimer's disease.
ES2089736T3 (es) * 1992-10-28 1996-10-01 Shionogi & Co Derivados de bencilideno.
US6251928B1 (en) 1994-03-16 2001-06-26 Eli Lilly And Company Treatment of alzheimer's disease employing inhibitors of cathepsin D
US5563277A (en) * 1994-12-21 1996-10-08 Eli Lilly And Company Process for preparing benzyl-substituted rhodanine derivatives
ATE198476T1 (de) * 1995-09-07 2001-01-15 Lilly Co Eli Alternative kristallform von tazofelon ((+,-)-5- ((3,5-bis(1,1-dimethylethyl)-4- hydroxyphenyl)methyl)-4-thiazolidinon)
ES2146837T3 (es) * 1995-09-07 2000-08-16 Lilly Co Eli Procedimiento para preparar derivados de la rodanina sustituidos con bencilo.
EP0779282A1 (en) * 1995-12-14 1997-06-18 Eli Lilly And Company Thiomorpholinone compounds for treating multiple sclerosis
US5981523A (en) * 1996-02-05 1999-11-09 Eli Lilly And Company Compounds and methods for treating multiple sclerosis
US6063799A (en) * 1996-09-03 2000-05-16 Eli Lilly And Company Alternate crystal form of Tazofelone
US6005142A (en) 1996-09-03 1999-12-21 Eli Lilly And Company Process for preparing benzyl-substituted rhodanine derivatives
AU6330799A (en) 1998-09-30 2000-04-17 Roche Diagnostics Gmbh Rhodanine carboxylic acid derivatives for the treatment and prevention of metabolic bone disorders
AU6331099A (en) * 1998-09-30 2000-04-17 Roche Diagnostics Gmbh Thiazolidine derivatives for the treatment and prevention of metabolic bone disorders
AU6330999A (en) * 1998-09-30 2000-04-17 Roche Diagnostics Gmbh Rhodanine derivatives for the treatment and prevention of metabolic bone disorders
US7235573B2 (en) 2002-09-30 2007-06-26 The Regents Of The University Of California Methods of treating secretory diarrhea using cystic fibrosis transmembrane conductance regulator protein inhibitors
CA2500498C (en) * 2002-09-30 2012-08-21 The Regents Of The University Of California Cystic fibrosis transmembrane conductance regulator protein inhibitors and uses thereof
AU2002953533A0 (en) 2002-12-24 2003-01-16 Arthron Limited Fc receptor modulating compounds and compositions
AU2011240367B2 (en) * 2010-04-15 2015-07-16 Merck Patent Gmbh Process for the preparation of hydroquinones

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT83152B (pt) * 1985-08-09 1989-03-30 Lilly Co Eli Processo para a preparacao de compostos di-t-butilfenoicos
IE62214B1 (en) * 1988-05-25 1995-01-11 Warner Lambert Co Arylmethylenyl derivatives of thiazolidinones, imidazolidinones and oxazolidinones useful as antiallergy agents and antiinflammatory agents
EP0391644B1 (en) * 1989-04-07 1996-06-19 Eli Lilly And Company Aryl-substituted rhodanine derivatives

Also Published As

Publication number Publication date
RU2050355C1 (ru) 1995-12-20
DK0434394T3 (da) 1998-12-14
EP0434394A3 (en) 1992-01-08
PT96198B (pt) 1998-05-29
PT96198A (pt) 1991-09-30
IL96654A (en) 1995-06-29
NZ236472A (en) 1993-03-26
FI906273A0 (fi) 1990-12-19
NO905478D0 (no) 1990-12-19
CN1029846C (zh) 1995-09-27
RU2036915C1 (ru) 1995-06-09
IL108962A (en) 1996-12-05
AU6826690A (en) 1991-06-27
IE904633A1 (en) 1991-07-17
DE69032537T2 (de) 1999-01-21
HU908368D0 (en) 1991-07-29
AU639734B2 (en) 1993-08-05
CY2100B1 (en) 2002-04-05
FI104251B1 (fi) 1999-12-15
NO300458B1 (no) 1997-06-02
ZA9010041B (en) 1992-08-26
KR0176243B1 (ko) 1999-03-20
FI104251B (fi) 1999-12-15
CA2032330C (en) 2001-05-08
YU240690A (sh) 1992-12-21
CN1052668A (zh) 1991-07-03
EP0434394A2 (en) 1991-06-26
EP0434394B1 (en) 1998-08-05
JP3036853B2 (ja) 2000-04-24
CA2032330A1 (en) 1991-06-22
FI19991698A (fi) 1999-08-10
JPH04279573A (ja) 1992-10-05
ATE169294T1 (de) 1998-08-15
IL108962A0 (en) 1994-06-24
HUT59915A (en) 1992-07-28
FI906273A (fi) 1991-06-22
HU216732B (hu) 1999-08-30
DE69032537D1 (de) 1998-09-10
KR910011812A (ko) 1991-08-07
ES2121748T3 (es) 1998-12-16
NO905478L (no) 1991-06-24

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