NO905478D0 - Benzylsubstituerte rhodaninderivater og fremgangsmaate forderes fremstilling. - Google Patents

Benzylsubstituerte rhodaninderivater og fremgangsmaate forderes fremstilling.

Info

Publication number
NO905478D0
NO905478D0 NO905478A NO905478A NO905478D0 NO 905478 D0 NO905478 D0 NO 905478D0 NO 905478 A NO905478 A NO 905478A NO 905478 A NO905478 A NO 905478A NO 905478 D0 NO905478 D0 NO 905478D0
Authority
NO
Norway
Prior art keywords
benzyl
rhodanine derivatives
substituted rhodanine
procedures
prepared
Prior art date
Application number
NO905478A
Other languages
English (en)
Other versions
NO300458B1 (no
NO905478L (no
Inventor
Jaswant Singh Gidda
Jill Ann Panetta
Michael Leroy Phillips
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NO905478D0 publication Critical patent/NO905478D0/no
Publication of NO905478L publication Critical patent/NO905478L/no
Publication of NO300458B1 publication Critical patent/NO300458B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/14Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/36Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Surgical Instruments (AREA)
  • Nonmetallic Welding Materials (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Eye Examination Apparatus (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO905478A 1989-12-21 1990-12-19 Analogifremgangsmåte for fremstilling av terapeutisk aktive benzylsubstituerte rhodaninderivater NO300458B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US45420389A 1989-12-21 1989-12-21

Publications (3)

Publication Number Publication Date
NO905478D0 true NO905478D0 (no) 1990-12-19
NO905478L NO905478L (no) 1991-06-24
NO300458B1 NO300458B1 (no) 1997-06-02

Family

ID=23803709

Family Applications (1)

Application Number Title Priority Date Filing Date
NO905478A NO300458B1 (no) 1989-12-21 1990-12-19 Analogifremgangsmåte for fremstilling av terapeutisk aktive benzylsubstituerte rhodaninderivater

Country Status (22)

Country Link
EP (1) EP0434394B1 (no)
JP (1) JP3036853B2 (no)
KR (1) KR0176243B1 (no)
CN (1) CN1029846C (no)
AT (1) ATE169294T1 (no)
AU (1) AU639734B2 (no)
CA (1) CA2032330C (no)
CY (1) CY2100B1 (no)
DE (1) DE69032537T2 (no)
DK (1) DK0434394T3 (no)
ES (1) ES2121748T3 (no)
FI (2) FI104251B1 (no)
HU (1) HU216732B (no)
IE (1) IE904633A1 (no)
IL (3) IL96654A (no)
MX (1) MX23803A (no)
NO (1) NO300458B1 (no)
NZ (1) NZ236472A (no)
PT (1) PT96198B (no)
RU (2) RU2036915C1 (no)
YU (1) YU240690A (no)
ZA (1) ZA9010041B (no)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU87339A1 (fr) * 1988-09-20 1990-04-06 Oreal Nouveaux derives de benzylidene-cyclanones,leur procede de preparation,leur utilisation en tant qu'agents anti-oxydants et comme filtres solaires,compositions cosmetiques et pharmaceutiques les contenant
US5143928A (en) * 1990-03-27 1992-09-01 Warner-Lambert Company 3,5-di-tertiarybutyl-4-hydroxyphenylmethylene derivatives of 2-substituted thiazolidinones, oxazolidinones, and imidazolidinones as antiinflammatory agents
NZ248573A (en) * 1992-09-10 1996-02-27 Lilly Co Eli 5-arylmethyl (and methylidene) thiazolidin-4-one derivatives; their preparation and pharmaceutical compositions
DK0595546T3 (da) * 1992-10-28 1996-04-15 Shionogi & Co Benzylidenderivater
US6251928B1 (en) * 1994-03-16 2001-06-26 Eli Lilly And Company Treatment of alzheimer's disease employing inhibitors of cathepsin D
US5563277A (en) * 1994-12-21 1996-10-08 Eli Lilly And Company Process for preparing benzyl-substituted rhodanine derivatives
SI0761657T1 (en) * 1995-09-07 2000-10-31 Eli Lilly And Company Process for preparing benzyl-substituted rhodanine derivatives
TW460471B (en) * 1995-09-07 2001-10-21 Lilly Co Eli Alternate crystal form of tazofelone
EP0779282A1 (en) * 1995-12-14 1997-06-18 Eli Lilly And Company Thiomorpholinone compounds for treating multiple sclerosis
US5981523A (en) * 1996-02-05 1999-11-09 Eli Lilly And Company Compounds and methods for treating multiple sclerosis
US6063799A (en) * 1996-09-03 2000-05-16 Eli Lilly And Company Alternate crystal form of Tazofelone
US6005142A (en) 1996-09-03 1999-12-21 Eli Lilly And Company Process for preparing benzyl-substituted rhodanine derivatives
AU6330799A (en) * 1998-09-30 2000-04-17 Roche Diagnostics Gmbh Rhodanine carboxylic acid derivatives for the treatment and prevention of metabolic bone disorders
AU6331099A (en) * 1998-09-30 2000-04-17 Roche Diagnostics Gmbh Thiazolidine derivatives for the treatment and prevention of metabolic bone disorders
WO2000018748A1 (en) * 1998-09-30 2000-04-06 Roche Diagnostics Gmbh Rhodanine derivatives for the treatment and prevention of metabolic bone disorders
US7235573B2 (en) 2002-09-30 2007-06-26 The Regents Of The University Of California Methods of treating secretory diarrhea using cystic fibrosis transmembrane conductance regulator protein inhibitors
KR20050061501A (ko) * 2002-09-30 2005-06-22 더 리전트 오브 더 유니버시티 오브 캘리포니아 낭종 섬유증 트랜스막 전도도 조절기 단백질 억제제 및이의 용도
AU2002953533A0 (en) * 2002-12-24 2003-01-16 Arthron Limited Fc receptor modulating compounds and compositions
CN102844286B (zh) * 2010-04-15 2014-12-31 默克专利股份有限公司 制备氢醌的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT83152B (pt) * 1985-08-09 1989-03-30 Lilly Co Eli Processo para a preparacao de compostos di-t-butilfenoicos
IE940525L (en) * 1988-05-25 1989-11-25 Warner Lambert Co Known and selected novel arylmethylenyl derivatives of¹thiazolidinones, imidazolidinones and oxazolidinones useful¹as antiallergy agents and antiinflammatory agents
ZA902520B (en) * 1989-04-07 1991-12-24 Lilly Co Eli Aryl-substituted rhodanine derivatives

Also Published As

Publication number Publication date
EP0434394A3 (en) 1992-01-08
CN1029846C (zh) 1995-09-27
YU240690A (sh) 1992-12-21
HU908368D0 (en) 1991-07-29
IL96654A (en) 1995-06-29
NO300458B1 (no) 1997-06-02
JP3036853B2 (ja) 2000-04-24
JPH04279573A (ja) 1992-10-05
CA2032330C (en) 2001-05-08
DK0434394T3 (da) 1998-12-14
FI104251B (fi) 1999-12-15
ES2121748T3 (es) 1998-12-16
HU216732B (hu) 1999-08-30
RU2036915C1 (ru) 1995-06-09
CA2032330A1 (en) 1991-06-22
IL108962A0 (en) 1994-06-24
AU6826690A (en) 1991-06-27
ZA9010041B (en) 1992-08-26
NO905478L (no) 1991-06-24
DE69032537T2 (de) 1999-01-21
AU639734B2 (en) 1993-08-05
FI19991698A (fi) 1999-08-10
CN1052668A (zh) 1991-07-03
RU2050355C1 (ru) 1995-12-20
PT96198B (pt) 1998-05-29
CY2100B1 (en) 2002-04-05
ATE169294T1 (de) 1998-08-15
IL108962A (en) 1996-12-05
EP0434394B1 (en) 1998-08-05
FI104251B1 (fi) 1999-12-15
EP0434394A2 (en) 1991-06-26
MX23803A (es) 1994-02-28
HUT59915A (en) 1992-07-28
PT96198A (pt) 1991-09-30
KR0176243B1 (ko) 1999-03-20
IE904633A1 (en) 1991-07-17
NZ236472A (en) 1993-03-26
FI906273A0 (fi) 1990-12-19
FI906273A (fi) 1991-06-22
KR910011812A (ko) 1991-08-07
DE69032537D1 (de) 1998-09-10

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MM1K Lapsed by not paying the annual fees

Free format text: LAPSED IN JUNE 2002