DE69032537D1 - Verbindungen zur Behandlung von Bauchentzündungen - Google Patents
Verbindungen zur Behandlung von BauchentzündungenInfo
- Publication number
- DE69032537D1 DE69032537D1 DE69032537T DE69032537T DE69032537D1 DE 69032537 D1 DE69032537 D1 DE 69032537D1 DE 69032537 T DE69032537 T DE 69032537T DE 69032537 T DE69032537 T DE 69032537T DE 69032537 D1 DE69032537 D1 DE 69032537D1
- Authority
- DE
- Germany
- Prior art keywords
- benzyl
- connections
- treatment
- rhodanine derivatives
- substituted rhodanine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/14—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/34—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/36—Sulfur atoms
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US45420389A | 1989-12-21 | 1989-12-21 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69032537D1 true DE69032537D1 (de) | 1998-09-10 |
DE69032537T2 DE69032537T2 (de) | 1999-01-21 |
Family
ID=23803709
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69032537T Expired - Fee Related DE69032537T2 (de) | 1989-12-21 | 1990-12-19 | Verbindungen zur Behandlung von Bauchentzündungen |
Country Status (22)
Country | Link |
---|---|
EP (1) | EP0434394B1 (de) |
JP (1) | JP3036853B2 (de) |
KR (1) | KR0176243B1 (de) |
CN (1) | CN1029846C (de) |
AT (1) | ATE169294T1 (de) |
AU (1) | AU639734B2 (de) |
CA (1) | CA2032330C (de) |
CY (1) | CY2100B1 (de) |
DE (1) | DE69032537T2 (de) |
DK (1) | DK0434394T3 (de) |
ES (1) | ES2121748T3 (de) |
FI (2) | FI104251B1 (de) |
HU (1) | HU216732B (de) |
IE (1) | IE904633A1 (de) |
IL (3) | IL108962A (de) |
MX (1) | MX23803A (de) |
NO (1) | NO300458B1 (de) |
NZ (1) | NZ236472A (de) |
PT (1) | PT96198B (de) |
RU (2) | RU2036915C1 (de) |
YU (1) | YU240690A (de) |
ZA (1) | ZA9010041B (de) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
LU87339A1 (fr) * | 1988-09-20 | 1990-04-06 | Oreal | Nouveaux derives de benzylidene-cyclanones,leur procede de preparation,leur utilisation en tant qu'agents anti-oxydants et comme filtres solaires,compositions cosmetiques et pharmaceutiques les contenant |
US5143928A (en) * | 1990-03-27 | 1992-09-01 | Warner-Lambert Company | 3,5-di-tertiarybutyl-4-hydroxyphenylmethylene derivatives of 2-substituted thiazolidinones, oxazolidinones, and imidazolidinones as antiinflammatory agents |
NZ248573A (en) * | 1992-09-10 | 1996-02-27 | Lilly Co Eli | 5-arylmethyl (and methylidene) thiazolidin-4-one derivatives; their preparation and pharmaceutical compositions |
DE69301894T2 (de) * | 1992-10-28 | 1996-11-07 | Shionogi & Co | Benzylidenderivate |
US6251928B1 (en) | 1994-03-16 | 2001-06-26 | Eli Lilly And Company | Treatment of alzheimer's disease employing inhibitors of cathepsin D |
US5563277A (en) * | 1994-12-21 | 1996-10-08 | Eli Lilly And Company | Process for preparing benzyl-substituted rhodanine derivatives |
SI0761657T1 (en) * | 1995-09-07 | 2000-10-31 | Eli Lilly And Company | Process for preparing benzyl-substituted rhodanine derivatives |
AR003483A1 (es) * | 1995-09-07 | 1998-08-05 | Lilly Co Eli | Procedimiento para preparar y aislar la forma ii de la (±)-5-[3,5-bis(1,1- dimetil)-4-hidroxifenil)-metil)-4-tiazolidinona. |
EP0779282A1 (de) * | 1995-12-14 | 1997-06-18 | Eli Lilly And Company | Thiomorpholinon-Verbindungen zur Behandlung von Multiple-Sklerose |
US5981523A (en) * | 1996-02-05 | 1999-11-09 | Eli Lilly And Company | Compounds and methods for treating multiple sclerosis |
US6005142A (en) * | 1996-09-03 | 1999-12-21 | Eli Lilly And Company | Process for preparing benzyl-substituted rhodanine derivatives |
US6063799A (en) * | 1996-09-03 | 2000-05-16 | Eli Lilly And Company | Alternate crystal form of Tazofelone |
WO2000018748A1 (en) * | 1998-09-30 | 2000-04-06 | Roche Diagnostics Gmbh | Rhodanine derivatives for the treatment and prevention of metabolic bone disorders |
AU6331099A (en) * | 1998-09-30 | 2000-04-17 | Roche Diagnostics Gmbh | Thiazolidine derivatives for the treatment and prevention of metabolic bone disorders |
US6673816B1 (en) | 1998-09-30 | 2004-01-06 | Angelika Esswein | Rhodanine carboxylic acid derivatives for the treatment and prevention of metabolic bone disorders |
US7235573B2 (en) | 2002-09-30 | 2007-06-26 | The Regents Of The University Of California | Methods of treating secretory diarrhea using cystic fibrosis transmembrane conductance regulator protein inhibitors |
JP4977319B2 (ja) * | 2002-09-30 | 2012-07-18 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 嚢胞性線維症膜コンダクタンス制御因子蛋白質阻害薬およびその使用方法 |
AU2002953533A0 (en) | 2002-12-24 | 2003-01-16 | Arthron Limited | Fc receptor modulating compounds and compositions |
AU2011240367B2 (en) * | 2010-04-15 | 2015-07-16 | Merck Patent Gmbh | Process for the preparation of hydroquinones |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1285572C (en) * | 1985-08-09 | 1991-07-02 | Jill Ann Panetta | Di-t-butylphenol compounds |
IE940525L (en) * | 1988-05-25 | 1989-11-25 | Warner Lambert Co | Known and selected novel arylmethylenyl derivatives of¹thiazolidinones, imidazolidinones and oxazolidinones useful¹as antiallergy agents and antiinflammatory agents |
ZA902520B (en) * | 1989-04-07 | 1991-12-24 | Lilly Co Eli | Aryl-substituted rhodanine derivatives |
-
1990
- 1990-12-13 ZA ZA9010041A patent/ZA9010041B/xx unknown
- 1990-12-13 IL IL10896290A patent/IL108962A/en not_active IP Right Cessation
- 1990-12-13 IL IL9665490A patent/IL96654A/en not_active IP Right Cessation
- 1990-12-14 NZ NZ236472A patent/NZ236472A/xx unknown
- 1990-12-14 PT PT96198A patent/PT96198B/pt active IP Right Grant
- 1990-12-14 CA CA002032330A patent/CA2032330C/en not_active Expired - Fee Related
- 1990-12-19 ES ES90313923T patent/ES2121748T3/es not_active Expired - Lifetime
- 1990-12-19 AU AU68266/90A patent/AU639734B2/en not_active Ceased
- 1990-12-19 EP EP90313923A patent/EP0434394B1/de not_active Expired - Lifetime
- 1990-12-19 NO NO905478A patent/NO300458B1/no not_active IP Right Cessation
- 1990-12-19 AT AT90313923T patent/ATE169294T1/de not_active IP Right Cessation
- 1990-12-19 KR KR1019900021001A patent/KR0176243B1/ko not_active IP Right Cessation
- 1990-12-19 FI FI906273A patent/FI104251B1/fi not_active IP Right Cessation
- 1990-12-19 MX MX2380390A patent/MX23803A/es unknown
- 1990-12-19 DE DE69032537T patent/DE69032537T2/de not_active Expired - Fee Related
- 1990-12-19 DK DK90313923T patent/DK0434394T3/da active
- 1990-12-20 RU SU904894177A patent/RU2036915C1/ru active
- 1990-12-20 YU YU240690A patent/YU240690A/sh unknown
- 1990-12-20 JP JP2413313A patent/JP3036853B2/ja not_active Expired - Fee Related
- 1990-12-20 CN CN90109846A patent/CN1029846C/zh not_active Expired - Fee Related
- 1990-12-20 IE IE463390A patent/IE904633A1/en not_active Application Discontinuation
- 1990-12-20 HU HU908368A patent/HU216732B/hu not_active IP Right Cessation
-
1991
- 1991-12-24 RU SU915010352A patent/RU2050355C1/ru active
-
1994
- 1994-03-14 IL IL10896294A patent/IL108962A0/xx unknown
-
1998
- 1998-09-07 CY CY9800024A patent/CY2100B1/xx unknown
-
1999
- 1999-08-10 FI FI991698A patent/FI19991698A/fi unknown
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |