ATE196085T1 - Verfahren und zusammensetzung zur behandlung von infektionen unter verwendung von optisch reinem (r) - lomefloxacin - Google Patents
Verfahren und zusammensetzung zur behandlung von infektionen unter verwendung von optisch reinem (r) - lomefloxacinInfo
- Publication number
- ATE196085T1 ATE196085T1 AT93900612T AT93900612T ATE196085T1 AT E196085 T1 ATE196085 T1 AT E196085T1 AT 93900612 T AT93900612 T AT 93900612T AT 93900612 T AT93900612 T AT 93900612T AT E196085 T1 ATE196085 T1 AT E196085T1
- Authority
- AT
- Austria
- Prior art keywords
- lomefloxacin
- optically pure
- composition
- treating infections
- isomer
- Prior art date
Links
- 229960002422 lomefloxacin Drugs 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 208000015181 infectious disease Diseases 0.000 title abstract 2
- ZEKZLJVOYLTDKK-UHFFFAOYSA-N lomefloxacin Chemical compound FC1=C2N(CC)C=C(C(O)=O)C(=O)C2=CC(F)=C1N1CCNC(C)C1 ZEKZLJVOYLTDKK-UHFFFAOYSA-N 0.000 abstract 2
- 230000002411 adverse Effects 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80066891A | 1991-11-27 | 1991-11-27 | |
| PCT/US1992/010144 WO1993010786A1 (en) | 1991-11-27 | 1992-11-25 | Methods and compositions for treating infection using optically pure (r)-lomefloxacin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE196085T1 true ATE196085T1 (de) | 2000-09-15 |
Family
ID=25179035
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93900612T ATE196085T1 (de) | 1991-11-27 | 1992-11-25 | Verfahren und zusammensetzung zur behandlung von infektionen unter verwendung von optisch reinem (r) - lomefloxacin |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0661974B1 (de) |
| JP (1) | JPH07501546A (de) |
| AT (1) | ATE196085T1 (de) |
| AU (2) | AU3223693A (de) |
| CA (1) | CA2124444A1 (de) |
| DE (1) | DE69231423T2 (de) |
| DK (1) | DK0661974T3 (de) |
| ES (1) | ES2149196T3 (de) |
| GR (1) | GR3034919T3 (de) |
| PT (1) | PT661974E (de) |
| WO (1) | WO1993010786A1 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6075024A (en) * | 1991-11-27 | 2000-06-13 | Sepracor Inc. | Methods for treating infection using optically pure (S)-lomefloxacin |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU553415B2 (en) * | 1983-09-19 | 1986-07-17 | Abbott Japan Co., Ltd. | 6-fluoro-1-4-dihydro-4-oxo-7-substituted piperazinyl- quinoline-3-carboxylic acids |
| JPS60190777A (ja) * | 1984-03-12 | 1985-09-28 | Hokuriku Seiyaku Co Ltd | 光学活性な６，８−ジフルオロ−１，４−ジヒドロ−４−オキソ−７−置換ピペラジニルキノリン−３−カルボン酸誘導体 |
| JP2676521B2 (ja) * | 1988-03-22 | 1997-11-17 | 北陸製薬株式会社 | キノロンカルボン酸化合物ｉ型結晶の製造法 |
-
1992
- 1992-11-25 AT AT93900612T patent/ATE196085T1/de not_active IP Right Cessation
- 1992-11-25 WO PCT/US1992/010144 patent/WO1993010786A1/en not_active Ceased
- 1992-11-25 PT PT93900612T patent/PT661974E/pt unknown
- 1992-11-25 DK DK93900612T patent/DK0661974T3/da active
- 1992-11-25 ES ES93900612T patent/ES2149196T3/es not_active Expired - Lifetime
- 1992-11-25 EP EP93900612A patent/EP0661974B1/de not_active Expired - Lifetime
- 1992-11-25 AU AU32236/93A patent/AU3223693A/en not_active Abandoned
- 1992-11-25 CA CA002124444A patent/CA2124444A1/en not_active Abandoned
- 1992-11-25 DE DE69231423T patent/DE69231423T2/de not_active Expired - Fee Related
- 1992-11-25 JP JP5510221A patent/JPH07501546A/ja active Pending
-
1997
- 1997-03-07 AU AU15152/97A patent/AU1515297A/en not_active Abandoned
-
2000
- 2000-11-28 GR GR20000402625T patent/GR3034919T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2124444A1 (en) | 1993-06-10 |
| DE69231423T2 (de) | 2001-01-04 |
| GR3034919T3 (en) | 2001-02-28 |
| DK0661974T3 (da) | 2000-10-16 |
| AU3223693A (en) | 1993-06-28 |
| PT661974E (pt) | 2001-02-28 |
| ES2149196T3 (es) | 2000-11-01 |
| EP0661974B1 (de) | 2000-09-06 |
| JPH07501546A (ja) | 1995-02-16 |
| WO1993010786A1 (en) | 1993-06-10 |
| EP0661974A4 (de) | 1994-08-29 |
| EP0661974A1 (de) | 1995-07-12 |
| AU1515297A (en) | 1997-05-22 |
| DE69231423D1 (de) | 2000-10-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REN | Ceased due to non-payment of the annual fee |