MX2022013890A - Sintesis y derivados de acido boronico, formas polimorficas y usos terapeuticos de los mismos. - Google Patents
Sintesis y derivados de acido boronico, formas polimorficas y usos terapeuticos de los mismos.Info
- Publication number
- MX2022013890A MX2022013890A MX2022013890A MX2022013890A MX2022013890A MX 2022013890 A MX2022013890 A MX 2022013890A MX 2022013890 A MX2022013890 A MX 2022013890A MX 2022013890 A MX2022013890 A MX 2022013890A MX 2022013890 A MX2022013890 A MX 2022013890A
- Authority
- MX
- Mexico
- Prior art keywords
- acid derivatives
- boronic acid
- polymorphic forms
- synthesis
- therapeutic uses
- Prior art date
Links
- 150000001642 boronic acid derivatives Chemical class 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 230000000845 anti-microbial effect Effects 0.000 abstract 1
- 238000012575 bio-layer interferometry Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/04—Esters of boric acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
- B01J23/38—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals
- B01J23/40—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals of the platinum group metals
- B01J23/44—Palladium
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
- B01J23/70—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of the iron group metals or copper
- B01J23/74—Iron group metals
- B01J23/755—Nickel
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Materials Engineering (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
En la presente se describen compuestos antimicrobianos, formas polimórficas, composiciones, composiciones farmacéuticas, el método de uso y preparación de los mismos. Algunas modalidades se refieren a derivados de ácido borónico y su uso como agentes terapéuticos, por ejemplo, inhibidores de ß-lactamasa (BLI).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063020494P | 2020-05-05 | 2020-05-05 | |
| PCT/US2021/030690 WO2021226114A1 (en) | 2020-05-05 | 2021-05-04 | Boronic acid derivatives and synthesis, polymorphic forms, and therapeutic uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2022013890A true MX2022013890A (es) | 2022-11-30 |
Family
ID=78468362
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2022013890A MX2022013890A (es) | 2020-05-05 | 2021-05-04 | Sintesis y derivados de acido boronico, formas polimorficas y usos terapeuticos de los mismos. |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP4149949A4 (es) |
| JP (1) | JP2023524525A (es) |
| KR (1) | KR20230020419A (es) |
| CN (1) | CN115996933A (es) |
| AU (1) | AU2021266715A1 (es) |
| BR (1) | BR112022022367A2 (es) |
| CA (1) | CA3180499A1 (es) |
| IL (1) | IL297458A (es) |
| MX (1) | MX2022013890A (es) |
| TW (1) | TW202207945A (es) |
| WO (1) | WO2021226114A1 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114539305B (zh) * | 2022-02-24 | 2023-10-31 | 川北医学院 | 一种通过对苯并呋喃去芳构化制备双键有机化合物的方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT3478693T (pt) * | 2016-06-30 | 2021-10-25 | Qpex Biopharma Inc | Derivados de ácido borónico e suas utilizações terapêuticas |
| BR112020007138B1 (pt) * | 2017-10-11 | 2023-03-21 | Qpex Biopharma, Inc | Derivados de ácido borônico, métodos de síntese, composição farmacêutica e uso dos mesmos |
-
2021
- 2021-05-04 CN CN202180047607.3A patent/CN115996933A/zh active Pending
- 2021-05-04 IL IL297458A patent/IL297458A/en unknown
- 2021-05-04 WO PCT/US2021/030690 patent/WO2021226114A1/en active Application Filing
- 2021-05-04 JP JP2022567085A patent/JP2023524525A/ja active Pending
- 2021-05-04 AU AU2021266715A patent/AU2021266715A1/en active Pending
- 2021-05-04 KR KR1020227042544A patent/KR20230020419A/ko active Search and Examination
- 2021-05-04 CA CA3180499A patent/CA3180499A1/en active Pending
- 2021-05-04 EP EP21800914.0A patent/EP4149949A4/en active Pending
- 2021-05-04 MX MX2022013890A patent/MX2022013890A/es unknown
- 2021-05-04 BR BR112022022367A patent/BR112022022367A2/pt unknown
- 2021-05-05 TW TW110116200A patent/TW202207945A/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2021266715A1 (en) | 2022-11-17 |
| IL297458A (en) | 2022-12-01 |
| WO2021226114A1 (en) | 2021-11-11 |
| TW202207945A (zh) | 2022-03-01 |
| BR112022022367A2 (pt) | 2023-01-10 |
| KR20230020419A (ko) | 2023-02-10 |
| EP4149949A1 (en) | 2023-03-22 |
| JP2023524525A (ja) | 2023-06-12 |
| CA3180499A1 (en) | 2021-11-11 |
| CN115996933A (zh) | 2023-04-21 |
| EP4149949A4 (en) | 2024-05-15 |
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