PT1322648E - Derivados de acidos 3-(heteroarilacetamido)-2-oxo-azetidina-1-sulfonicos como agentes antibacterianos - Google Patents

Derivados de acidos 3-(heteroarilacetamido)-2-oxo-azetidina-1-sulfonicos como agentes antibacterianos

Info

Publication number
PT1322648E
PT1322648E PT01980829T PT01980829T PT1322648E PT 1322648 E PT1322648 E PT 1322648E PT 01980829 T PT01980829 T PT 01980829T PT 01980829 T PT01980829 T PT 01980829T PT 1322648 E PT1322648 E PT 1322648E
Authority
PT
Portugal
Prior art keywords
azetidine
oxo
heteroarylethylamid
sulfonics
acid derivatives
Prior art date
Application number
PT01980829T
Other languages
English (en)
Inventor
Ronald George Micetich
Maiti Samarendra Nath
Fiakpui Charles
Thomas George
Reddy Andhe V Narender
Sameeh M Salama
Singh Rajeshwar
Original Assignee
Pantherix Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pantherix Ltd filed Critical Pantherix Ltd
Publication of PT1322648E publication Critical patent/PT1322648E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
PT01980829T 2000-09-14 2001-09-14 Derivados de acidos 3-(heteroarilacetamido)-2-oxo-azetidina-1-sulfonicos como agentes antibacterianos PT1322648E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US23261700P 2000-09-14 2000-09-14

Publications (1)

Publication Number Publication Date
PT1322648E true PT1322648E (pt) 2005-11-30

Family

ID=22873854

Family Applications (1)

Application Number Title Priority Date Filing Date
PT01980829T PT1322648E (pt) 2000-09-14 2001-09-14 Derivados de acidos 3-(heteroarilacetamido)-2-oxo-azetidina-1-sulfonicos como agentes antibacterianos

Country Status (23)

Country Link
US (1) US6916803B2 (pt)
EP (1) EP1322648B1 (pt)
JP (1) JP2004509122A (pt)
KR (1) KR100854810B1 (pt)
CN (1) CN1189469C (pt)
AT (1) ATE298750T1 (pt)
AU (2) AU2002212614B2 (pt)
BR (1) BR0113861A (pt)
CA (1) CA2422375C (pt)
CZ (1) CZ304586B6 (pt)
DE (1) DE60111757T2 (pt)
DK (1) DK1322648T3 (pt)
ES (1) ES2244666T3 (pt)
HK (1) HK1054377A1 (pt)
HU (1) HUP0301025A3 (pt)
IL (2) IL154593A0 (pt)
NO (1) NO324946B1 (pt)
NZ (1) NZ524292A (pt)
PL (1) PL218196B1 (pt)
PT (1) PT1322648E (pt)
SK (1) SK2462003A3 (pt)
WO (1) WO2002022613A1 (pt)
ZA (1) ZA200302085B (pt)

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AU2012233003B2 (en) * 2005-12-07 2014-12-18 Basilea Pharmaceutica Ag Useful combinations of monobactam antibiotics with beta-lactamase inhibitors
PT2308874E (pt) 2005-12-07 2013-04-26 Basilea Pharmaceutica Ag Monobactamas ligadas por pontes, úteis como inibidores de beta-lactamase
RU2488394C2 (ru) * 2007-03-23 2013-07-27 Базилеа Фармацойтика Аг Комбинированные лекарственные средства для лечения бактериальных инфекций
WO2009114921A1 (en) * 2008-03-17 2009-09-24 Dmitrienko Gary I INHIBITORS OF CLASS B AND CLASS D β-LACTAMASES
JP6266978B2 (ja) 2010-08-10 2018-01-24 レンペックス・ファーマシューティカルズ・インコーポレイテッド 環状ボロン酸エステル誘導体およびその治療的使用
US9012491B2 (en) 2011-08-31 2015-04-21 Rempex Pharmaceuticals, Inc. Heterocyclic boronic acid ester derivatives and therapeutic uses thereof
UY34585A (es) * 2012-01-24 2013-09-02 Aicuris Gmbh & Co Kg Compuestos b-lactámicos sustituidos con amidina, su preparación y uso
US9156858B2 (en) 2012-05-23 2015-10-13 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
US10561675B2 (en) 2012-06-06 2020-02-18 Rempex Pharmaceuticals, Inc. Cyclic boronic acid ester derivatives and therapeutic uses thereof
CN102757405B (zh) * 2012-07-25 2014-04-16 山东理工大学 含噻二唑的香兰素衍生物、其制备方法及其用途
US9642869B2 (en) 2013-01-04 2017-05-09 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
US9101638B2 (en) 2013-01-04 2015-08-11 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
WO2014107536A1 (en) 2013-01-04 2014-07-10 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
US9241947B2 (en) 2013-01-04 2016-01-26 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
LT3140310T (lt) 2014-05-05 2019-11-25 Rempex Pharmaceuticals Inc Boronato druskų sintezė ir jų panaudojimas
WO2015171398A1 (en) 2014-05-05 2015-11-12 Rempex Pharmaceuticals, Inc. Salts and polymorphs of cyclic boronic acid ester derivatives and therapeutic uses thereof
BR112016026291A2 (pt) 2014-05-19 2017-08-15 Rempex Pharmaceuticals Inc Derivados do ácido borônico e usos terapêuticos dos mesmos
KR20170024087A (ko) 2014-07-01 2017-03-06 렘펙스 파머수티클스 인코퍼레이티드 보론산 유도체 및 그의 치료적 용도
US10662205B2 (en) 2014-11-18 2020-05-26 Qpex Biopharma, Inc. Cyclic boronic acid ester derivatives and therapeutic uses thereof
US10364257B2 (en) 2014-12-19 2019-07-30 Rempex Pharmaceuticals, Inc. Apparatus and continuous flow process for production of boronic acid derivatives
WO2016149393A1 (en) 2015-03-17 2016-09-22 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
CA3026582A1 (en) 2016-06-30 2018-01-04 Qpex Biopharma, Inc. Boronic acid derivatives and therapeutic uses thereof
CN107641119B (zh) 2016-07-21 2019-11-08 中国科学院上海药物研究所 单环β-内酰胺-铁载体轭合物及其制备方法和用途
US20200093814A1 (en) 2016-12-21 2020-03-26 Aicuris Gmbh & Co. Kg Combination therapy with amidine substituted beta-lactam compounds and beta-lactamase inhibitors for infections with antibiotic resistant bacterial strains
MX2020003495A (es) 2017-10-11 2020-09-18 Qpex Biopharma Inc Derivados de acido boronico y sintesis de los mismos.
CN111511737B (zh) 2018-01-29 2022-10-18 南京明德新药研发有限公司 用于治疗细菌感染的单环β-内酰胺化合物
WO2020125670A1 (zh) 2018-12-18 2020-06-25 南京明德新药研发有限公司 单环β-内酰胺化合物在制药中的应用
SI25892A (sl) * 2019-09-05 2021-03-31 Gorenje Gospodinjski Aparati, D.O.O. Pralni stroj, ki se polni s sprednje strani, z električnim svetlobnim telesom
US11040987B2 (en) 2019-09-11 2021-06-22 Tennor Therapeutics Limited Penam derivatives for treating bacterial infections
JP7446424B2 (ja) 2019-11-22 2024-03-08 スージョウ アーイェ ファーマシューティカル カンパニー リミテッド スルホニル尿素環置換単環式β－ラクタム系抗生物質
WO2021121387A1 (zh) 2019-12-19 2021-06-24 南京明德新药研发有限公司 化合物在制药中的应用
CN113754651B (zh) * 2020-06-02 2023-04-18 中国医学科学院医药生物技术研究所 一种β-内酰胺化合物、其用途及其制备方法
CA3229556A1 (en) * 2021-08-20 2023-02-23 Marvin Miller Conjugates of monocyclic beta-lactams and siderophore mimetics
CN115304594B (zh) 2022-10-12 2023-02-14 苏州二叶制药有限公司 磺酰脲环取代的化合物的盐型及其晶型

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GB8810396D0 (en) 1988-05-03 1988-06-08 Glaxo Group Ltd Chemical process
US5112968A (en) * 1989-07-28 1992-05-12 E. R. Squibb & Sons, Inc. Monobactam hydrazide derivatives
US5250691A (en) * 1991-09-09 1993-10-05 E. R. Squibb & Sons, Inc. Heteroaryl derivatives of monocyclic beta-lactam antibiotics
US5888998A (en) * 1997-04-24 1999-03-30 Synphar Laboratories, Inc. 2-oxo-1-azetidine sulfonic acid derivatives as potent β-lactamase inhibitors
US5994340A (en) * 1997-08-29 1999-11-30 Synphar Laboratories, Inc. Azetidinone derivatives as β-lactamase inhibitors

Also Published As

Publication number Publication date
KR100854810B1 (ko) 2008-08-27
US20040019203A1 (en) 2004-01-29
DE60111757D1 (de) 2005-08-04
AU1261402A (en) 2002-03-26
ZA200302085B (en) 2004-03-15
WO2002022613A1 (en) 2002-03-21
NZ524292A (en) 2004-09-24
ES2244666T3 (es) 2005-12-16
PL360537A1 (en) 2004-09-06
CA2422375A1 (en) 2002-03-21
HUP0301025A3 (en) 2009-03-30
JP2004509122A (ja) 2004-03-25
IL154593A0 (en) 2003-09-17
NO20031162L (no) 2003-03-13
US6916803B2 (en) 2005-07-12
BR0113861A (pt) 2004-01-27
NO324946B1 (no) 2008-01-07
CZ304586B6 (cs) 2014-07-23
ATE298750T1 (de) 2005-07-15
CZ2003606A3 (cs) 2003-08-13
CN1189469C (zh) 2005-02-16
PL218196B1 (pl) 2014-10-31
AU2002212614B2 (en) 2006-12-07
SK2462003A3 (en) 2003-09-11
HK1054377A1 (en) 2003-11-28
IL154593A (en) 2008-06-05
DE60111757T2 (de) 2006-04-27
HUP0301025A2 (hu) 2004-04-28
CA2422375C (en) 2011-03-15
DK1322648T3 (da) 2005-10-31
EP1322648B1 (en) 2005-06-29
CN1458932A (zh) 2003-11-26
EP1322648A1 (en) 2003-07-02
KR20030039369A (ko) 2003-05-17
NO20031162D0 (no) 2003-03-13

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