DK1618106T3 - Carbacephem beta-lactam antibiotika - Google Patents

Carbacephem beta-lactam antibiotika

Info

Publication number
DK1618106T3
DK1618106T3 DK04750798.3T DK04750798T DK1618106T3 DK 1618106 T3 DK1618106 T3 DK 1618106T3 DK 04750798 T DK04750798 T DK 04750798T DK 1618106 T3 DK1618106 T3 DK 1618106T3
Authority
DK
Denmark
Prior art keywords
carbacephem
beta
lactam antibiotics
antibiotics
methicillin
Prior art date
Application number
DK04750798.3T
Other languages
English (en)
Inventor
Tomasz W Glinka
Scott J Hecker
Original Assignee
Trine Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Trine Pharmaceuticals Inc filed Critical Trine Pharmaceuticals Inc
Application granted granted Critical
Publication of DK1618106T3 publication Critical patent/DK1618106T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0827Tripeptides containing heteroatoms different from O, S, or N
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D463/00Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16Nitrogen atoms
    • C07D463/18Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D463/22Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
DK04750798.3T 2003-04-30 2004-04-27 Carbacephem beta-lactam antibiotika DK1618106T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46698203P 2003-04-30 2003-04-30
PCT/US2004/013054 WO2004098500A2 (en) 2003-04-30 2004-04-27 CARBACEPHEM ss-LACTAM ANTIBIOTICS

Publications (1)

Publication Number Publication Date
DK1618106T3 true DK1618106T3 (da) 2010-03-15

Family

ID=33435002

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04750798.3T DK1618106T3 (da) 2003-04-30 2004-04-27 Carbacephem beta-lactam antibiotika

Country Status (10)

Country Link
US (1) US7109190B2 (da)
EP (2) EP2161268A1 (da)
JP (1) JP2006525340A (da)
AT (1) ATE449775T1 (da)
CA (1) CA2526875A1 (da)
DE (1) DE602004024297D1 (da)
DK (1) DK1618106T3 (da)
ES (1) ES2336917T3 (da)
MX (1) MXPA05011681A (da)
WO (1) WO2004098500A2 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090123367A1 (en) * 2003-03-05 2009-05-14 Delfmems Soluble Glycosaminoglycanases and Methods of Preparing and Using Soluble Glycosaminoglycanases
CA2517145C (en) * 2003-03-05 2017-08-01 Halozyme, Inc. Soluble hyaluronidase glycoprotein (shasegp), process for preparing the same, uses and pharmaceutical compositions comprising thereof
US7871607B2 (en) 2003-03-05 2011-01-18 Halozyme, Inc. Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases
US20060104968A1 (en) 2003-03-05 2006-05-18 Halozyme, Inc. Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminogly ycanases
US20080146535A1 (en) * 2003-04-30 2008-06-19 Tomasz Glinka Compositions comprising carbacephem beta-lactam antibiotics and beta-lactamase inhibitors
US8263613B2 (en) 2007-02-16 2012-09-11 Affinium Pharmaceuticals, Inc. Salts, prodrugs and polymorphs of fab I inhibitors
EA201070504A1 (ru) * 2007-10-25 2010-12-30 Эйкеоджен, Инк. КАРБАЦЕФЕМ β-ЛАКТАМОВЫЕ АНТИБИОТИКИ
WO2010030810A1 (en) * 2008-09-10 2010-03-18 Achaogen, Inc. Carbacephem beta-lactam antibiotics
WO2010030811A2 (en) * 2008-09-10 2010-03-18 Achaogen, Inc. CARBACEPHEM β-LACTAM ANTIBIOTICS
WO2010123997A1 (en) * 2009-04-22 2010-10-28 Achaogen, Inc. Carbacephem beta-lactam antibiotics
BR112020000196A2 (pt) 2017-07-07 2020-07-07 Epicentrx, Inc. composições para administração parenteral de agentes terapêuticos

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60174787A (ja) * 1984-02-21 1985-09-09 Kyowa Hakko Kogyo Co Ltd 3位置換カルバセフエム化合物
NO165842C (no) * 1984-04-23 1991-04-17 Takeda Chemical Industries Ltd Analogifremgangsmaate for fremstilling av terapeutisk aktive cefem-forbindelser.
US4788185A (en) * 1984-04-23 1988-11-29 Takeda Chemical Industries, Ltd. Cephalosporin compounds
JPH0830070B2 (ja) * 1985-09-27 1996-03-27 武田薬品工業株式会社 抗菌性化合物
US4826834A (en) * 1985-09-27 1989-05-02 Takeda Chemical Industries, Ltd. Cephem compounds
US5077287A (en) * 1991-01-18 1991-12-31 Eli Lilly And Company 3-thiazolylthio carbacephem antibacterial agents
US5565445A (en) * 1995-02-22 1996-10-15 Merck & Co., Inc. 3-thioheteroaryl 1-carba-1-dethiacephalosporin compounds, compositions and methods of use
AR029004A1 (es) * 1999-09-22 2003-06-04 Essential Therapeutics Inc Compuesto del acido 7-acilamino-3-heteroariltio-3-cefem carboxilico y su uso para la preparacion de una composicion antibacteriana
US6599893B2 (en) * 2000-08-29 2003-07-29 Essential Therapeutics, Inc. Cephalosporin antibiotics and prodrugs thereof

Also Published As

Publication number Publication date
CA2526875A1 (en) 2004-11-18
MXPA05011681A (es) 2006-06-27
EP1618106B1 (en) 2009-11-25
EP1618106A4 (en) 2006-11-22
EP1618106A2 (en) 2006-01-25
EP2161268A1 (en) 2010-03-10
DE602004024297D1 (de) 2010-01-07
JP2006525340A (ja) 2006-11-09
WO2004098500A2 (en) 2004-11-18
US20050004095A1 (en) 2005-01-06
ATE449775T1 (de) 2009-12-15
WO2004098500A3 (en) 2005-06-02
ES2336917T3 (es) 2010-04-19
US7109190B2 (en) 2006-09-19

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