ATE449775T1 - Carbacephem beta-lactam-antibiotika - Google Patents
Carbacephem beta-lactam-antibiotikaInfo
- Publication number
- ATE449775T1 ATE449775T1 AT04750798T AT04750798T ATE449775T1 AT E449775 T1 ATE449775 T1 AT E449775T1 AT 04750798 T AT04750798 T AT 04750798T AT 04750798 T AT04750798 T AT 04750798T AT E449775 T1 ATE449775 T1 AT E449775T1
- Authority
- AT
- Austria
- Prior art keywords
- carbacephem
- beta
- lactam antibiotics
- antibiotics
- methicillin
- Prior art date
Links
- JSVCEVCSANKFDY-SFYZADRCSA-N carbacephem Chemical compound C1CC(C)=C(C(O)=O)N2C(=O)[C@@H](NC(=O)C)[C@H]21 JSVCEVCSANKFDY-SFYZADRCSA-N 0.000 title abstract 2
- 239000003782 beta lactam antibiotic agent Substances 0.000 title 1
- 239000002132 β-lactam antibiotic Substances 0.000 title 1
- 229940124586 β-lactam antibiotics Drugs 0.000 title 1
- 241000894006 Bacteria Species 0.000 abstract 1
- 208000035143 Bacterial infection Diseases 0.000 abstract 1
- RJQXTJLFIWVMTO-TYNCELHUSA-N Methicillin Chemical compound COC1=CC=CC(OC)=C1C(=O)N[C@@H]1C(=O)N2[C@@H](C(O)=O)C(C)(C)S[C@@H]21 RJQXTJLFIWVMTO-TYNCELHUSA-N 0.000 abstract 1
- 241000191940 Staphylococcus Species 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 229960003085 meticillin Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
- C07D463/16—Nitrogen atoms
- C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
- C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46698203P | 2003-04-30 | 2003-04-30 | |
| PCT/US2004/013054 WO2004098500A2 (en) | 2003-04-30 | 2004-04-27 | CARBACEPHEM ss-LACTAM ANTIBIOTICS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE449775T1 true ATE449775T1 (de) | 2009-12-15 |
Family
ID=33435002
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04750798T ATE449775T1 (de) | 2003-04-30 | 2004-04-27 | Carbacephem beta-lactam-antibiotika |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7109190B2 (de) |
| EP (2) | EP1618106B1 (de) |
| JP (1) | JP2006525340A (de) |
| AT (1) | ATE449775T1 (de) |
| CA (1) | CA2526875A1 (de) |
| DE (1) | DE602004024297D1 (de) |
| DK (1) | DK1618106T3 (de) |
| ES (1) | ES2336917T3 (de) |
| MX (1) | MXPA05011681A (de) |
| WO (1) | WO2004098500A2 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7871607B2 (en) * | 2003-03-05 | 2011-01-18 | Halozyme, Inc. | Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases |
| KR20130135986A (ko) * | 2003-03-05 | 2013-12-11 | 할로자임, 아이엔씨 | 가용성 하이알우로니다제 당단백질 (ｓＨＡＳＥＧＰ), 이를 제조하는 방법, 용도 및 이를 포함하는 약학 조성물 |
| US20060104968A1 (en) | 2003-03-05 | 2006-05-18 | Halozyme, Inc. | Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminogly ycanases |
| US20090123367A1 (en) * | 2003-03-05 | 2009-05-14 | Delfmems | Soluble Glycosaminoglycanases and Methods of Preparing and Using Soluble Glycosaminoglycanases |
| US20080146535A1 (en) * | 2003-04-30 | 2008-06-19 | Tomasz Glinka | Compositions comprising carbacephem beta-lactam antibiotics and beta-lactamase inhibitors |
| US8263613B2 (en) * | 2007-02-16 | 2012-09-11 | Affinium Pharmaceuticals, Inc. | Salts, prodrugs and polymorphs of fab I inhibitors |
| CA2701286A1 (en) * | 2007-10-25 | 2009-04-30 | Achaogen, Inc. | Carbacephem .beta.-lactam antibiotics |
| WO2010030811A2 (en) * | 2008-09-10 | 2010-03-18 | Achaogen, Inc. | CARBACEPHEM β-LACTAM ANTIBIOTICS |
| WO2010030810A1 (en) * | 2008-09-10 | 2010-03-18 | Achaogen, Inc. | Carbacephem beta-lactam antibiotics |
| WO2010123997A1 (en) * | 2009-04-22 | 2010-10-28 | Achaogen, Inc. | Carbacephem beta-lactam antibiotics |
| JP7377791B2 (ja) | 2017-07-07 | 2023-11-10 | エピセントアールエックス，インコーポレイテッド | 治療剤の非経口投与のための組成物 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60174787A (ja) * | 1984-02-21 | 1985-09-09 | Kyowa Hakko Kogyo Co Ltd | ３位置換カルバセフエム化合物 |
| NO165842C (no) * | 1984-04-23 | 1991-04-17 | Takeda Chemical Industries Ltd | Analogifremgangsmaate for fremstilling av terapeutisk aktive cefem-forbindelser. |
| US4788185A (en) * | 1984-04-23 | 1988-11-29 | Takeda Chemical Industries, Ltd. | Cephalosporin compounds |
| US4826834A (en) * | 1985-09-27 | 1989-05-02 | Takeda Chemical Industries, Ltd. | Cephem compounds |
| JPH0830070B2 (ja) * | 1985-09-27 | 1996-03-27 | 武田薬品工業株式会社 | 抗菌性化合物 |
| US5077287A (en) * | 1991-01-18 | 1991-12-31 | Eli Lilly And Company | 3-thiazolylthio carbacephem antibacterial agents |
| US5565445A (en) * | 1995-02-22 | 1996-10-15 | Merck & Co., Inc. | 3-thioheteroaryl 1-carba-1-dethiacephalosporin compounds, compositions and methods of use |
| AR029004A1 (es) * | 1999-09-22 | 2003-06-04 | Essential Therapeutics Inc | Compuesto del acido 7-acilamino-3-heteroariltio-3-cefem carboxilico y su uso para la preparacion de una composicion antibacteriana |
| US6599893B2 (en) * | 2000-08-29 | 2003-07-29 | Essential Therapeutics, Inc. | Cephalosporin antibiotics and prodrugs thereof |
-
2004
- 2004-04-27 JP JP2006513383A patent/JP2006525340A/ja active Pending
- 2004-04-27 MX MXPA05011681A patent/MXPA05011681A/es active IP Right Grant
- 2004-04-27 DE DE602004024297T patent/DE602004024297D1/de not_active Expired - Lifetime
- 2004-04-27 ES ES04750798T patent/ES2336917T3/es not_active Expired - Lifetime
- 2004-04-27 DK DK04750798.3T patent/DK1618106T3/da active
- 2004-04-27 AT AT04750798T patent/ATE449775T1/de not_active IP Right Cessation
- 2004-04-27 US US10/833,599 patent/US7109190B2/en not_active Expired - Fee Related
- 2004-04-27 WO PCT/US2004/013054 patent/WO2004098500A2/en not_active Ceased
- 2004-04-27 CA CA002526875A patent/CA2526875A1/en not_active Abandoned
- 2004-04-27 EP EP04750798A patent/EP1618106B1/de not_active Expired - Lifetime
- 2004-04-27 EP EP09176059A patent/EP2161268A1/de not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004098500A2 (en) | 2004-11-18 |
| EP1618106A4 (de) | 2006-11-22 |
| DK1618106T3 (da) | 2010-03-15 |
| US20050004095A1 (en) | 2005-01-06 |
| US7109190B2 (en) | 2006-09-19 |
| EP2161268A1 (de) | 2010-03-10 |
| ES2336917T3 (es) | 2010-04-19 |
| EP1618106B1 (de) | 2009-11-25 |
| MXPA05011681A (es) | 2006-06-27 |
| DE602004024297D1 (de) | 2010-01-07 |
| JP2006525340A (ja) | 2006-11-09 |
| CA2526875A1 (en) | 2004-11-18 |
| WO2004098500A3 (en) | 2005-06-02 |
| EP1618106A2 (de) | 2006-01-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |