EA200200413A1 - Пролекарства гигромицина а - Google Patents

Пролекарства гигромицина а

Info

Publication number
EA200200413A1
EA200200413A1 EA200200413A EA200200413A EA200200413A1 EA 200200413 A1 EA200200413 A1 EA 200200413A1 EA 200200413 A EA200200413 A EA 200200413A EA 200200413 A EA200200413 A EA 200200413A EA 200200413 A1 EA200200413 A1 EA 200200413A1
Authority
EA
Eurasian Patent Office
Prior art keywords
formula
compounds
infections
relates
protozoal infections
Prior art date
Application number
EA200200413A
Other languages
English (en)
Inventor
Такуси Канеко
Original Assignee
Пфайзер Продактс Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Пфайзер Продактс Инк. filed Critical Пфайзер Продактс Инк.
Publication of EA200200413A1 publication Critical patent/EA200200413A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Настоящее изобретение относится к соединениям формулы (I) и их фармацевтически приемлемым солям и сольватам, где а, b, X, Y, Z, R, Rи Rимеют определенные в описании значения, которые являются антибактериальными и антипротозойными агентами, и могут быть использованы для лечения различных бактериальных и протозойных инфекций и заболеваний, связанных с такими инфекциями. Изобретение также относится к фармацевтическим композициям, содержащим соединения формулы (I), а также к способам лечения бактериальных и протозойных инфекций путем введения соединений формулы (I).Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200200413A 1999-10-29 2000-09-28 Пролекарства гигромицина а EA200200413A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16272299P 1999-10-29 1999-10-29
PCT/IB2000/001390 WO2001030793A1 (en) 1999-10-29 2000-09-28 Hygromycin a prodrugs

Publications (1)

Publication Number Publication Date
EA200200413A1 true EA200200413A1 (ru) 2002-10-31

Family

ID=22586880

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200200413A EA200200413A1 (ru) 1999-10-29 2000-09-28 Пролекарства гигромицина а

Country Status (32)

Country Link
US (1) US6492342B1 (ru)
EP (1) EP1224194A1 (ru)
JP (1) JP2003512472A (ru)
KR (1) KR20020043255A (ru)
CN (1) CN1382149A (ru)
AP (1) AP2002002492A0 (ru)
AR (1) AR026285A1 (ru)
AU (1) AU7307900A (ru)
BG (1) BG106635A (ru)
BR (1) BR0015156A (ru)
CA (1) CA2389019A1 (ru)
CO (1) CO5261547A1 (ru)
CZ (1) CZ20021347A3 (ru)
EA (1) EA200200413A1 (ru)
EC (1) ECSP003743A (ru)
EE (1) EE200200226A (ru)
GT (1) GT200000178A (ru)
HK (1) HK1049844A1 (ru)
HU (1) HUP0203223A2 (ru)
IL (1) IL148580A0 (ru)
IS (1) IS6312A (ru)
MA (1) MA26839A1 (ru)
MX (1) MXPA02004359A (ru)
NO (1) NO20021822L (ru)
OA (1) OA12079A (ru)
PE (1) PE20010757A1 (ru)
PL (1) PL357080A1 (ru)
SK (1) SK5322002A3 (ru)
SV (1) SV2002000210A (ru)
TN (1) TNSN00209A1 (ru)
TR (1) TR200201143T2 (ru)
WO (1) WO2001030793A1 (ru)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3840743A4 (en) * 2018-08-20 2022-08-17 Northeastern University HYGROMYCIN A COMPOUNDS AND METHODS OF TREATING SPIROCHETE DISEASES

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL142882A0 (en) * 1998-12-02 2002-03-10 Pfizer Prod Inc Hygromycin a derivatives as antibacterial agents

Also Published As

Publication number Publication date
CZ20021347A3 (cs) 2002-11-13
HK1049844A1 (zh) 2003-05-30
MXPA02004359A (es) 2002-11-07
AP2002002492A0 (en) 2002-06-30
AR026285A1 (es) 2003-02-05
WO2001030793A1 (en) 2001-05-03
EP1224194A1 (en) 2002-07-24
ECSP003743A (es) 2002-05-23
SV2002000210A (es) 2002-06-07
NO20021822D0 (no) 2002-04-18
MA26839A1 (fr) 2004-12-20
PL357080A1 (en) 2004-07-12
BG106635A (en) 2002-12-29
PE20010757A1 (es) 2001-07-25
US6492342B1 (en) 2002-12-10
CA2389019A1 (en) 2001-05-03
BR0015156A (pt) 2002-07-16
TNSN00209A1 (fr) 2005-11-10
SK5322002A3 (en) 2003-01-09
KR20020043255A (ko) 2002-06-08
IL148580A0 (en) 2002-09-12
GT200000178A (es) 2002-04-09
IS6312A (is) 2002-03-19
TR200201143T2 (tr) 2002-08-21
JP2003512472A (ja) 2003-04-02
CN1382149A (zh) 2002-11-27
HUP0203223A2 (en) 2003-02-28
OA12079A (en) 2006-05-04
EE200200226A (et) 2003-06-16
CO5261547A1 (es) 2003-03-31
NO20021822L (no) 2002-04-18
AU7307900A (en) 2001-05-08

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