HUP0301025A3 - 3-(heteroaryl acetamido)-2-oxo-azetidine-1-sulfonic acids derivatives as antibacterial agents, process for their preparation and pharmaceutical compositions containing them - Google Patents

3-(heteroaryl acetamido)-2-oxo-azetidine-1-sulfonic acids derivatives as antibacterial agents, process for their preparation and pharmaceutical compositions containing them

Info

Publication number
HUP0301025A3
HUP0301025A3 HU0301025A HUP0301025A HUP0301025A3 HU P0301025 A3 HUP0301025 A3 HU P0301025A3 HU 0301025 A HU0301025 A HU 0301025A HU P0301025 A HUP0301025 A HU P0301025A HU P0301025 A3 HUP0301025 A3 HU P0301025A3
Authority
HU
Hungary
Prior art keywords
azetidine
oxo
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
HU0301025A
Other languages
English (en)
Original Assignee
Basilea Pharmaceutica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basilea Pharmaceutica Ag filed Critical Basilea Pharmaceutica Ag
Publication of HUP0301025A2 publication Critical patent/HUP0301025A2/hu
Publication of HUP0301025A3 publication Critical patent/HUP0301025A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HU0301025A 2000-09-14 2001-09-14 3-(heteroaryl acetamido)-2-oxo-azetidine-1-sulfonic acids derivatives as antibacterial agents, process for their preparation and pharmaceutical compositions containing them HUP0301025A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23261700P 2000-09-14 2000-09-14
PCT/IB2001/002115 WO2002022613A1 (en) 2000-09-14 2001-09-14 3-(heteroaryl acetamido)-2-oxo-azetidine-1-sulfonic acids derivatives as antibacterial agents

Publications (2)

Publication Number Publication Date
HUP0301025A2 HUP0301025A2 (hu) 2004-04-28
HUP0301025A3 true HUP0301025A3 (en) 2009-03-30

Family

ID=22873854

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0301025A HUP0301025A3 (en) 2000-09-14 2001-09-14 3-(heteroaryl acetamido)-2-oxo-azetidine-1-sulfonic acids derivatives as antibacterial agents, process for their preparation and pharmaceutical compositions containing them

Country Status (23)

Country Link
US (1) US6916803B2 (hu)
EP (1) EP1322648B1 (hu)
JP (1) JP2004509122A (hu)
KR (1) KR100854810B1 (hu)
CN (1) CN1189469C (hu)
AT (1) ATE298750T1 (hu)
AU (2) AU1261402A (hu)
BR (1) BR0113861A (hu)
CA (1) CA2422375C (hu)
CZ (1) CZ304586B6 (hu)
DE (1) DE60111757T2 (hu)
DK (1) DK1322648T3 (hu)
ES (1) ES2244666T3 (hu)
HK (1) HK1054377A1 (hu)
HU (1) HUP0301025A3 (hu)
IL (2) IL154593A0 (hu)
NO (1) NO324946B1 (hu)
NZ (1) NZ524292A (hu)
PL (1) PL218196B1 (hu)
PT (1) PT1322648E (hu)
SK (1) SK2462003A3 (hu)
WO (1) WO2002022613A1 (hu)
ZA (1) ZA200302085B (hu)

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US8901293B2 (en) * 2005-12-07 2014-12-02 Basilea Pharmaceutica Ag Useful combinations of monobactam antibiotics with beta-lactamase inhibitors
AU2012233003B2 (en) * 2005-12-07 2014-12-18 Basilea Pharmaceutica Ag Useful combinations of monobactam antibiotics with beta-lactamase inhibitors
KR101320718B1 (ko) * 2007-03-23 2013-10-21 바실리어 파마슈티카 아게 세균 감염 치료용 조합 약제
US20110046101A1 (en) * 2008-03-17 2011-02-24 Dmitrienko Gary I Bate-lactamase inhibitors
RS60310B1 (sr) 2010-08-10 2020-07-31 Rempex Pharmaceuticals Inc Ciklični derivati estra boronske kiseline, postupak za pripremu injihove terapeutske upotrebe
US9012491B2 (en) 2011-08-31 2015-04-21 Rempex Pharmaceuticals, Inc. Heterocyclic boronic acid ester derivatives and therapeutic uses thereof
UY34585A (es) * 2012-01-24 2013-09-02 Aicuris Gmbh & Co Kg Compuestos b-lactámicos sustituidos con amidina, su preparación y uso
US9156858B2 (en) 2012-05-23 2015-10-13 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
US10561675B2 (en) 2012-06-06 2020-02-18 Rempex Pharmaceuticals, Inc. Cyclic boronic acid ester derivatives and therapeutic uses thereof
CN102757405B (zh) * 2012-07-25 2014-04-16 山东理工大学 含噻二唑的香兰素衍生物、其制备方法及其用途
US9101638B2 (en) 2013-01-04 2015-08-11 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
US9241947B2 (en) 2013-01-04 2016-01-26 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
US9642869B2 (en) 2013-01-04 2017-05-09 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
EP2941247A4 (en) 2013-01-04 2017-02-08 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
EP3139930A4 (en) 2014-05-05 2018-01-17 Rempex Pharmaceuticals, Inc. Salts and polymorphs of cyclic boronic acid ester derivatives and therapeutic uses thereof
HUE046836T2 (hu) 2014-05-05 2020-03-30 Rempex Pharmaceuticals Inc Boronát sók szintézise és alkalmazásuk
CN106459096B (zh) 2014-05-19 2019-03-08 莱姆派克斯制药公司 硼酸衍生物及其治疗用途
EA201692301A1 (ru) 2014-07-01 2017-06-30 Ремпекс Фармасьютикалз, Инк. Производные бороновой кислоты и их терапевтическое применение
WO2016081297A1 (en) 2014-11-18 2016-05-26 Rempex Pharmaceuticals, Inc. Cyclic boronic acid ester derivatives and therapeutic uses thereof
CN107207537B (zh) 2014-12-19 2019-05-31 莱姆派克斯制药公司 用于生产硼酸衍生物的设备和连续流方法
US20180051041A1 (en) 2015-03-17 2018-02-22 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
EP3478693B1 (en) 2016-06-30 2021-07-21 Qpex Biopharma, Inc. Boronic acid derivatives and therapeutic uses thereof
CN107641119B (zh) * 2016-07-21 2019-11-08 中国科学院上海药物研究所 单环β-内酰胺-铁载体轭合物及其制备方法和用途
WO2018065636A1 (en) 2016-12-21 2018-04-12 Aicuris Anti-Infective Cures Gmbh COMBINATION THERAPY WITH AMIDINE SUBSTITUTED ß-LACTAM COMPOUNDS AND ß-LACTAMASE INHIBITORS FOR INFECTIONS WITH ANTIBIOTIC RESISTANT BACTERIAL STRAINS
IL273551B2 (en) 2017-10-11 2024-02-01 Qpex Biopharma Inc Boronic acid derivatives and their synthesis
JP7280273B2 (ja) 2018-01-29 2023-05-23 メッドシャイン ディスカバリー インコーポレイテッド 細菌感染を治療するための単環β－ラクタム化合物
JP7179185B2 (ja) 2018-12-18 2022-11-28 メッドシャイン ディスカバリー インコーポレイテッド 医薬の製造おける単環式β－ラクタム化合物の使用
SI25892A (sl) * 2019-09-05 2021-03-31 Gorenje Gospodinjski Aparati, D.O.O. Pralni stroj, ki se polni s sprednje strani, z električnim svetlobnim telesom
JP2022548067A (ja) * 2019-09-11 2022-11-16 テンノア・セラピューティクス・（スージョウ）・リミテッド 細菌感染症を治療するためのペナム誘導体
KR20220084398A (ko) 2019-11-22 2022-06-21 쑤저우 얼예 파마슈티칼 컴퍼니 리미티드 설포닐우레아 고리 치환 모노시클릭 β-락탐계 항생제
US20230022708A1 (en) 2019-12-19 2023-01-26 Medshine Discovery Inc. Application of compound in drug preparation
CN113754651B (zh) * 2020-06-02 2023-04-18 中国医学科学院医药生物技术研究所 一种β-内酰胺化合物、其用途及其制备方法
CA3229556A1 (en) * 2021-08-20 2023-02-23 Marvin Miller Conjugates of monocyclic beta-lactams and siderophore mimetics
CN115304594B (zh) 2022-10-12 2023-02-14 苏州二叶制药有限公司 磺酰脲环取代的化合物的盐型及其晶型

Family Cites Families (6)

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Publication number Priority date Publication date Assignee Title
US4632985A (en) * 1985-06-03 1986-12-30 E. R. Squibb & Sons, Inc. 3-acylamino-2-oxo-1-azetidinesulfonic acids
GB8810396D0 (en) * 1988-05-03 1988-06-08 Glaxo Group Ltd Chemical process
US5112968A (en) 1989-07-28 1992-05-12 E. R. Squibb & Sons, Inc. Monobactam hydrazide derivatives
US5250691A (en) * 1991-09-09 1993-10-05 E. R. Squibb & Sons, Inc. Heteroaryl derivatives of monocyclic beta-lactam antibiotics
US5888998A (en) * 1997-04-24 1999-03-30 Synphar Laboratories, Inc. 2-oxo-1-azetidine sulfonic acid derivatives as potent β-lactamase inhibitors
US5994340A (en) 1997-08-29 1999-11-30 Synphar Laboratories, Inc. Azetidinone derivatives as β-lactamase inhibitors

Also Published As

Publication number Publication date
PL360537A1 (en) 2004-09-06
CZ2003606A3 (cs) 2003-08-13
ES2244666T3 (es) 2005-12-16
DK1322648T3 (da) 2005-10-31
BR0113861A (pt) 2004-01-27
CZ304586B6 (cs) 2014-07-23
CN1189469C (zh) 2005-02-16
IL154593A0 (en) 2003-09-17
EP1322648B1 (en) 2005-06-29
ZA200302085B (en) 2004-03-15
PL218196B1 (pl) 2014-10-31
AU2002212614B2 (en) 2006-12-07
CA2422375C (en) 2011-03-15
HK1054377A1 (en) 2003-11-28
JP2004509122A (ja) 2004-03-25
DE60111757D1 (de) 2005-08-04
HUP0301025A2 (hu) 2004-04-28
US20040019203A1 (en) 2004-01-29
WO2002022613A1 (en) 2002-03-21
ATE298750T1 (de) 2005-07-15
DE60111757T2 (de) 2006-04-27
IL154593A (en) 2008-06-05
NO20031162L (no) 2003-03-13
SK2462003A3 (en) 2003-09-11
NO20031162D0 (no) 2003-03-13
KR20030039369A (ko) 2003-05-17
CN1458932A (zh) 2003-11-26
NO324946B1 (no) 2008-01-07
PT1322648E (pt) 2005-11-30
KR100854810B1 (ko) 2008-08-27
CA2422375A1 (en) 2002-03-21
NZ524292A (en) 2004-09-24
AU1261402A (en) 2002-03-26
US6916803B2 (en) 2005-07-12
EP1322648A1 (en) 2003-07-02

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Legal Events

Date Code Title Description
GB9A Succession in title

Owner name: BASILEA PHARMACEUTICA AG, CH

Free format text: FORMER OWNER(S): PANTHERIX LTD., GB

FA9A Lapse of provisional patent protection due to relinquishment or protection considered relinquished