DK1322648T3 - 3-(heteroarylacetamido)-2-oxo-azetidin-1-sulfonsyrederivater som antibakterielle midler - Google Patents

3-(heteroarylacetamido)-2-oxo-azetidin-1-sulfonsyrederivater som antibakterielle midler

Info

Publication number
DK1322648T3
DK1322648T3 DK01980829T DK01980829T DK1322648T3 DK 1322648 T3 DK1322648 T3 DK 1322648T3 DK 01980829 T DK01980829 T DK 01980829T DK 01980829 T DK01980829 T DK 01980829T DK 1322648 T3 DK1322648 T3 DK 1322648T3
Authority
DK
Denmark
Prior art keywords
azetidine
oxo
heteroarylacetamido
sulfonic acid
acid derivatives
Prior art date
Application number
DK01980829T
Other languages
Danish (da)
English (en)
Inventor
Ronald George Micetich
Rajeshwar Singh
Samarendra Nath Maiti
Charles Fiakpui
George Thomas
Andhe V Narender Reddy
Sameeh M Salama
Original Assignee
Pantherix Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pantherix Ltd filed Critical Pantherix Ltd
Application granted granted Critical
Publication of DK1322648T3 publication Critical patent/DK1322648T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK01980829T 2000-09-14 2001-09-14 3-(heteroarylacetamido)-2-oxo-azetidin-1-sulfonsyrederivater som antibakterielle midler DK1322648T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23261700P 2000-09-14 2000-09-14
PCT/IB2001/002115 WO2002022613A1 (en) 2000-09-14 2001-09-14 3-(heteroaryl acetamido)-2-oxo-azetidine-1-sulfonic acids derivatives as antibacterial agents

Publications (1)

Publication Number Publication Date
DK1322648T3 true DK1322648T3 (da) 2005-10-31

Family

ID=22873854

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01980829T DK1322648T3 (da) 2000-09-14 2001-09-14 3-(heteroarylacetamido)-2-oxo-azetidin-1-sulfonsyrederivater som antibakterielle midler

Country Status (23)

Country Link
US (1) US6916803B2 (hu)
EP (1) EP1322648B1 (hu)
JP (1) JP2004509122A (hu)
KR (1) KR100854810B1 (hu)
CN (1) CN1189469C (hu)
AT (1) ATE298750T1 (hu)
AU (2) AU1261402A (hu)
BR (1) BR0113861A (hu)
CA (1) CA2422375C (hu)
CZ (1) CZ304586B6 (hu)
DE (1) DE60111757T2 (hu)
DK (1) DK1322648T3 (hu)
ES (1) ES2244666T3 (hu)
HK (1) HK1054377A1 (hu)
HU (1) HUP0301025A3 (hu)
IL (2) IL154593A0 (hu)
NO (1) NO324946B1 (hu)
NZ (1) NZ524292A (hu)
PL (1) PL218196B1 (hu)
PT (1) PT1322648E (hu)
SK (1) SK2462003A3 (hu)
WO (1) WO2002022613A1 (hu)
ZA (1) ZA200302085B (hu)

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KR101403164B1 (ko) * 2005-12-07 2014-06-03 바실리어 파마슈티카 아게 베타-락타마아제 저해제 및 모노박탐 항생물질의 유용한조합
AU2012233003B2 (en) * 2005-12-07 2014-12-18 Basilea Pharmaceutica Ag Useful combinations of monobactam antibiotics with beta-lactamase inhibitors
CN101641095B (zh) 2007-03-23 2012-10-31 巴斯利尔药物股份公司 用于治疗细菌感染的组合药物
WO2009114921A1 (en) * 2008-03-17 2009-09-24 Dmitrienko Gary I INHIBITORS OF CLASS B AND CLASS D β-LACTAMASES
PL3412676T3 (pl) 2010-08-10 2021-04-06 Melinta Therapeutics, Inc. Cykliczne pochodne estrowe kwasu boronowego, sposób otrzymywania oraz ich zastosowania terapeutyczne
WO2013033461A1 (en) 2011-08-31 2013-03-07 Rempex Pharmaceuticals, Inc. Heterocyclic boronic acid ester derivatives and therapeutic uses thereof
UY34585A (es) * 2012-01-24 2013-09-02 Aicuris Gmbh & Co Kg Compuestos b-lactámicos sustituidos con amidina, su preparación y uso
US9156858B2 (en) 2012-05-23 2015-10-13 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
US10561675B2 (en) 2012-06-06 2020-02-18 Rempex Pharmaceuticals, Inc. Cyclic boronic acid ester derivatives and therapeutic uses thereof
CN102757405B (zh) * 2012-07-25 2014-04-16 山东理工大学 含噻二唑的香兰素衍生物、其制备方法及其用途
KR20150103270A (ko) 2013-01-04 2015-09-09 렘펙스 파머수티클스 인코퍼레이티드 보론산 유도체 및 그의 치료적 용도
US9241947B2 (en) 2013-01-04 2016-01-26 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
KR20150103269A (ko) 2013-01-04 2015-09-09 렘펙스 파머수티클스 인코퍼레이티드 보론산 유도체 및 그의 치료적 용도
US9101638B2 (en) 2013-01-04 2015-08-11 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
WO2015171430A1 (en) 2014-05-05 2015-11-12 Rempex Pharmaceuticals, Inc. Synthesis of boronate salts and uses thereof
WO2015171398A1 (en) 2014-05-05 2015-11-12 Rempex Pharmaceuticals, Inc. Salts and polymorphs of cyclic boronic acid ester derivatives and therapeutic uses thereof
WO2015179308A1 (en) 2014-05-19 2015-11-26 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
KR20170024087A (ko) 2014-07-01 2017-03-06 렘펙스 파머수티클스 인코퍼레이티드 보론산 유도체 및 그의 치료적 용도
US10662205B2 (en) 2014-11-18 2020-05-26 Qpex Biopharma, Inc. Cyclic boronic acid ester derivatives and therapeutic uses thereof
ES2761778T3 (es) 2014-12-19 2020-05-21 Rempex Pharmaceuticals Inc Aparato y proceso de flujo continuo para la producción de derivados de ácido borónico
US20180051041A1 (en) 2015-03-17 2018-02-22 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
MY196909A (en) 2016-06-30 2023-05-09 Qpex Biopharma Inc Boronic acid derivatives and therapeutic uses thereof
CN107641119B (zh) * 2016-07-21 2019-11-08 中国科学院上海药物研究所 单环β-内酰胺-铁载体轭合物及其制备方法和用途
EA201991523A1 (ru) 2016-12-21 2019-11-29 Комбинированная терапия амидин-замещенными бета-лактамными соединениями и ингибиторами бета-лактамазы при инфекциях, вызванных бактериальными штаммами, резистентными к антибиотикам
IL273551B2 (en) 2017-10-11 2024-02-01 Qpex Biopharma Inc Boronic acid derivatives and their synthesis
JP7280273B2 (ja) 2018-01-29 2023-05-23 メッドシャイン ディスカバリー インコーポレイテッド 細菌感染を治療するための単環β－ラクタム化合物
CN113227088B (zh) 2018-12-18 2022-05-31 南京明德新药研发有限公司 单环β-内酰胺化合物在制药中的应用
SI25892A (sl) * 2019-09-05 2021-03-31 Gorenje Gospodinjski Aparati, D.O.O. Pralni stroj, ki se polni s sprednje strani, z električnim svetlobnim telesom
US11040987B2 (en) 2019-09-11 2021-06-22 Tennor Therapeutics Limited Penam derivatives for treating bacterial infections
JP7446424B2 (ja) 2019-11-22 2024-03-08 スージョウ アーイェ ファーマシューティカル カンパニー リミテッド スルホニル尿素環置換単環式β－ラクタム系抗生物質
EP4079305A4 (en) 2019-12-19 2024-01-10 Shenzhen Optimum Biological Technology Co., Ltd APPLICATION OF A COMPOUND IN THE PREPARATION OF DRUG
CN113754651B (zh) * 2020-06-02 2023-04-18 中国医学科学院医药生物技术研究所 一种β-内酰胺化合物、其用途及其制备方法
EP4387613A1 (en) * 2021-08-20 2024-06-26 University of Notre Dame du Lac Conjugates of monocyclic beta-lactams and siderophore mimetics
CN115304594B (zh) 2022-10-12 2023-02-14 苏州二叶制药有限公司 磺酰脲环取代的化合物的盐型及其晶型

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US5994340A (en) * 1997-08-29 1999-11-30 Synphar Laboratories, Inc. Azetidinone derivatives as β-lactamase inhibitors

Also Published As

Publication number Publication date
CZ2003606A3 (cs) 2003-08-13
AU1261402A (en) 2002-03-26
CZ304586B6 (cs) 2014-07-23
NO20031162L (no) 2003-03-13
HUP0301025A2 (hu) 2004-04-28
DE60111757D1 (de) 2005-08-04
WO2002022613A1 (en) 2002-03-21
PT1322648E (pt) 2005-11-30
ZA200302085B (en) 2004-03-15
US20040019203A1 (en) 2004-01-29
KR100854810B1 (ko) 2008-08-27
CN1189469C (zh) 2005-02-16
PL218196B1 (pl) 2014-10-31
NO324946B1 (no) 2008-01-07
CA2422375A1 (en) 2002-03-21
BR0113861A (pt) 2004-01-27
KR20030039369A (ko) 2003-05-17
PL360537A1 (en) 2004-09-06
AU2002212614B2 (en) 2006-12-07
DE60111757T2 (de) 2006-04-27
NZ524292A (en) 2004-09-24
HK1054377A1 (en) 2003-11-28
US6916803B2 (en) 2005-07-12
ES2244666T3 (es) 2005-12-16
IL154593A0 (en) 2003-09-17
JP2004509122A (ja) 2004-03-25
SK2462003A3 (en) 2003-09-11
ATE298750T1 (de) 2005-07-15
EP1322648A1 (en) 2003-07-02
NO20031162D0 (no) 2003-03-13
HUP0301025A3 (en) 2009-03-30
CN1458932A (zh) 2003-11-26
IL154593A (en) 2008-06-05
CA2422375C (en) 2011-03-15
EP1322648B1 (en) 2005-06-29

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