MX2022005677A - Procedimientos y reactivos de reaccion bioquimica que comprenden regiones intrinsecamente desordenadas. - Google Patents

Procedimientos y reactivos de reaccion bioquimica que comprenden regiones intrinsecamente desordenadas.

Info

Publication number
MX2022005677A
MX2022005677A MX2022005677A MX2022005677A MX2022005677A MX 2022005677 A MX2022005677 A MX 2022005677A MX 2022005677 A MX2022005677 A MX 2022005677A MX 2022005677 A MX2022005677 A MX 2022005677A MX 2022005677 A MX2022005677 A MX 2022005677A
Authority
MX
Mexico
Prior art keywords
macromolecules
polypeptides
biochemical reaction
relates
rids
Prior art date
Application number
MX2022005677A
Other languages
English (en)
Spanish (es)
Inventor
Niall Armes
Hannah Williams
Matthew Forrest
Mathew Parker
Sidong Liu
Lauren Parker
Original Assignee
Biocrucible Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocrucible Ltd filed Critical Biocrucible Ltd
Publication of MX2022005677A publication Critical patent/MX2022005677A/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2521/00—Reaction characterised by the enzymatic activity
    • C12Q2521/50—Other enzymatic activities
    • C12Q2521/507—Recombinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2522/00—Reaction characterised by the use of non-enzymatic proteins
    • C12Q2522/10—Nucleic acid binding proteins
    • C12Q2522/101—Single or double stranded nucleic acid binding proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2527/00—Reactions demanding special reaction conditions
    • C12Q2527/125—Specific component of sample, medium or buffer

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MX2022005677A 2019-11-11 2020-11-11 Procedimientos y reactivos de reaccion bioquimica que comprenden regiones intrinsecamente desordenadas. MX2022005677A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1916379.9A GB201916379D0 (en) 2019-11-11 2019-11-11 Biochemical reaction methods and reagents
PCT/GB2020/052866 WO2021094746A1 (en) 2019-11-11 2020-11-11 Biochemical reaction methods and reagents comprising intrinsically disordered regions

Publications (1)

Publication Number Publication Date
MX2022005677A true MX2022005677A (es) 2022-09-07

Family

ID=69062276

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022005677A MX2022005677A (es) 2019-11-11 2020-11-11 Procedimientos y reactivos de reaccion bioquimica que comprenden regiones intrinsecamente desordenadas.

Country Status (13)

Country Link
US (2) US12618102B2 (enExample)
EP (1) EP4058599A1 (enExample)
JP (2) JP7840266B2 (enExample)
KR (1) KR20220113948A (enExample)
CN (1) CN114945682A (enExample)
AU (1) AU2020382121B2 (enExample)
BR (1) BR112022009072A2 (enExample)
CA (1) CA3157435A1 (enExample)
GB (1) GB201916379D0 (enExample)
IL (1) IL292885A (enExample)
MX (1) MX2022005677A (enExample)
WO (1) WO2021094746A1 (enExample)
ZA (1) ZA202205093B (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
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CN108998406B (zh) * 2018-08-03 2022-05-10 福州大学 一种人类原代培养细胞基因组编辑、定点基因敲入方法
GB201916379D0 (en) 2019-11-11 2019-12-25 Biocrucible Ltd Biochemical reaction methods and reagents
CN113355389B (zh) * 2020-03-05 2022-11-15 广西扬翔股份有限公司 利用CRISPR/Cas12a系统靶向富集核酸目标区域的方法及其应用
EP3992635A1 (en) 2020-10-29 2022-05-04 midge medical GmbH System and a device for detecting a target analyte
US20240110221A1 (en) * 2022-09-30 2024-04-04 Illumina, Inc. Methods of modulating clustering kinetics
CN116251621B (zh) * 2022-12-13 2024-08-23 中国科学院基础医学与肿瘤研究所(筹) 一种提高氯化血红素的过氧化物酶活性的方法
WO2024178628A1 (en) * 2023-02-28 2024-09-06 Sun Yat-Sen University Epigenetic editor assisted by phase separation proteins
US12612667B1 (en) * 2023-05-01 2026-04-28 National Technology & Engineering Solutions Of Sandia, Llc Solid phase recombinase polymerase amplification for human pathogen identification
JP2024179837A (ja) * 2023-06-16 2024-12-26 国立大学法人 東京大学 酵素の検出方法及び酵素の検出キット
KR20250022285A (ko) 2023-08-07 2025-02-17 포항공과대학교 산학협력단 액체-액체 상분리를 통한 scotin 프롤린-풍부 도메인 생체분자 응축물 및 그의 응용
WO2025137528A1 (en) * 2023-12-20 2025-06-26 Abbott Laboratories Reducing agent compositions for isothermal amplification of nucleic acids
GB2643378A (en) * 2024-07-15 2026-02-18 Biocrucible Ltd Reagents and methods
WO2026131829A1 (en) 2024-12-16 2026-06-25 Neoenta LLC Devices for analysis of a biological sample and manufacturing methods thereof, and methods of anaylsis of a biological sample
GB202500508D0 (en) 2025-01-15 2025-02-26 Biocrucible Ltd Molecular diagnostic device

Family Cites Families (18)

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US7399590B2 (en) * 2002-02-21 2008-07-15 Asm Scientific, Inc. Recombinase polymerase amplification
DK1499738T3 (da) 2002-02-21 2008-11-17 Asm Scient Inc Recombinase-polymerease-amplifikation
CA2560758A1 (en) 2004-04-21 2005-11-03 Toray Industries, Inc. Lab-on-chip substrate
DE102005052752A1 (de) 2005-11-04 2007-05-10 Clondiag Chip Technologies Gmbh Vorrichtung und Verfahren zum Nachweis von molekularen Wechselwirkungen
EP2829615B1 (en) 2005-07-25 2018-05-09 Alere San Diego, Inc. Kit for multiplexing recombinase polymerase amplification
US20070059713A1 (en) 2005-09-09 2007-03-15 Lee Jun E SSB-DNA polymerase fusion proteins
EP2029782B1 (en) 2006-05-04 2014-11-26 Alere San Diego, Inc. Recombinase polymerase amplification
WO2008108927A2 (en) * 2007-03-06 2008-09-12 Regenerx Biopharmaceuticals, Inc. Methods and compositions for stabilizing polypeptides
CA2946024C (en) 2007-05-03 2020-06-02 Clondiag Gmbh Devices and methods for detecting analytes
US8560130B2 (en) 2007-12-04 2013-10-15 Lester F. Ludwig Software controlled lab-on-a-chip emulation
CN102026725B (zh) 2008-03-14 2014-10-29 科隆迪亚戈有限公司 一种用于检测样品中分析物的装置及其方法
WO2010141940A1 (en) 2009-06-05 2010-12-09 Alere San Diego, Inc. Recombinase polymerase amplification reagents and kits
KR20120093882A (ko) 2009-09-16 2012-08-23 마쎄이 유니버시티 융합 폴리펩티드 및 이들의 용도
JP6490576B2 (ja) 2012-04-12 2019-03-27 ニユー・イングランド・バイオレイブス・インコーポレイテツド 重合反応のための合成核酸
US10533167B2 (en) 2016-06-09 2020-01-14 The Trustees Of Princeton University Optogenetic tool for rapid and reversible clustering of proteins
WO2018100408A1 (en) * 2016-11-30 2018-06-07 Sasinapas Co.,Ltd. Modified peptides
EP3743435B1 (en) 2018-01-24 2023-08-09 The Trustees Of Princeton University System and method for inducing clusters of gene regulatory proteins targeted to specific genomic loci
GB201916379D0 (en) 2019-11-11 2019-12-25 Biocrucible Ltd Biochemical reaction methods and reagents

Also Published As

Publication number Publication date
GB201916379D0 (en) 2019-12-25
AU2020382121A1 (en) 2022-06-16
AU2020382121B2 (en) 2026-06-18
IL292885A (en) 2022-07-01
JP7840266B2 (ja) 2026-04-03
CA3157435A1 (en) 2021-05-20
CN114945682A (zh) 2022-08-26
JP2023501002A (ja) 2023-01-17
AU2020382121A8 (en) 2022-07-28
JP2026041819A (ja) 2026-03-10
US20220112547A1 (en) 2022-04-14
EP4058599A1 (en) 2022-09-21
BR112022009072A2 (pt) 2022-07-26
US11807899B2 (en) 2023-11-07
KR20220113948A (ko) 2022-08-17
ZA202205093B (en) 2024-10-30
WO2021094746A1 (en) 2021-05-20
US20220145378A1 (en) 2022-05-12
US12618102B2 (en) 2026-05-05

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