MX2019007444A - Metodos y sistemas para analisis de moleculas de acido nucleico. - Google Patents

Metodos y sistemas para analisis de moleculas de acido nucleico.

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Publication number
MX2019007444A
MX2019007444A MX2019007444A MX2019007444A MX2019007444A MX 2019007444 A MX2019007444 A MX 2019007444A MX 2019007444 A MX2019007444 A MX 2019007444A MX 2019007444 A MX2019007444 A MX 2019007444A MX 2019007444 A MX2019007444 A MX 2019007444A
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Mexico
Prior art keywords
methods
nucleic acid
systems
analysis
acid molecules
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MX2019007444A
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English (en)
Inventor
Abdueva Diana
Kennedy Andrew
Ann Ward MORTIMER Stefanie
Eltoukhy Helmy
Talasaz Amirali
Schultz Matthew
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Guardant Health Inc
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Application filed by Guardant Health Inc filed Critical Guardant Health Inc
Publication of MX2019007444A publication Critical patent/MX2019007444A/es

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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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    • C12Q2521/00—Reaction characterised by the enzymatic activity
    • C12Q2521/10—Nucleotidyl transfering
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    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
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    • C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
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    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
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    • C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/50—Detection characterised by immobilisation to a surface
    • C12Q2565/514—Detection characterised by immobilisation to a surface characterised by the use of the arrayed oligonucleotides as identifier tags, e.g. universal addressable array, anti-tag or tag complement array
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    • C12Q2600/00—Oligonucleotides characterized by their use
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  • Chemical & Material Sciences (AREA)
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Abstract

La descripción proporciona métodos para procesar poblaciones de ácidos nucleicos que contienen diferentes formas (por ejemplo, ARN y ADN, de hebra individual o doble hebra) y/o grados de modificación (por ejemplo, metilación de citosina, asociación con proteínas). Estos métodos se adaptan a múltiples formas y/o modificaciones de ácido nucleico en una muestra, de manera que se puede obtener información de secuencia para múltiples formas. Los métodos también preservan identidad de múltiples formas o estados modificados a través de procesamiento y análisis, de manera que el análisis de secuencia se puede combinar con análisis epigenético.
MX2019007444A 2016-12-22 2017-12-22 Metodos y sistemas para analisis de moleculas de acido nucleico. MX2019007444A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201662438240P 2016-12-22 2016-12-22
US201762512936P 2017-05-31 2017-05-31
US201762550540P 2017-08-25 2017-08-25
PCT/US2017/068329 WO2018119452A2 (en) 2016-12-22 2017-12-22 Methods and systems for analyzing nucleic acid molecules

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MX2019007444A true MX2019007444A (es) 2019-08-16

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US (2) US11519019B2 (es)
EP (1) EP3559270A2 (es)
JP (2) JP7300989B2 (es)
KR (1) KR20190095410A (es)
CN (1) CN110325650A (es)
AU (1) AU2017382439A1 (es)
BR (1) BR112019012958A2 (es)
CA (1) CA3046007A1 (es)
IL (2) IL302912A (es)
MX (1) MX2019007444A (es)
WO (1) WO2018119452A2 (es)

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