IL292885A - Methods of biochemical reactions and reagents containing intrinsically disorganized regions - Google Patents
Methods of biochemical reactions and reagents containing intrinsically disorganized regionsInfo
- Publication number
- IL292885A IL292885A IL292885A IL29288522A IL292885A IL 292885 A IL292885 A IL 292885A IL 292885 A IL292885 A IL 292885A IL 29288522 A IL29288522 A IL 29288522A IL 292885 A IL292885 A IL 292885A
- Authority
- IL
- Israel
- Prior art keywords
- idr
- polypeptide
- macromolecule
- reaction
- amino acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2521/00—Reaction characterised by the enzymatic activity
- C12Q2521/50—Other enzymatic activities
- C12Q2521/507—Recombinase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2522/00—Reaction characterised by the use of non-enzymatic proteins
- C12Q2522/10—Nucleic acid binding proteins
- C12Q2522/101—Single or double stranded nucleic acid binding proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2527/00—Reactions demanding special reaction conditions
- C12Q2527/125—Specific component of sample, medium or buffer
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1916379.9A GB201916379D0 (en) | 2019-11-11 | 2019-11-11 | Biochemical reaction methods and reagents |
| PCT/GB2020/052866 WO2021094746A1 (en) | 2019-11-11 | 2020-11-11 | Biochemical reaction methods and reagents comprising intrinsically disordered regions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL292885A true IL292885A (en) | 2022-07-01 |
Family
ID=69062276
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL292885A IL292885A (en) | 2019-11-11 | 2020-11-11 | Methods of biochemical reactions and reagents containing intrinsically disorganized regions |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US12618102B2 (enExample) |
| EP (1) | EP4058599A1 (enExample) |
| JP (2) | JP7840266B2 (enExample) |
| KR (1) | KR20220113948A (enExample) |
| CN (1) | CN114945682A (enExample) |
| AU (1) | AU2020382121B2 (enExample) |
| BR (1) | BR112022009072A2 (enExample) |
| CA (1) | CA3157435A1 (enExample) |
| GB (1) | GB201916379D0 (enExample) |
| IL (1) | IL292885A (enExample) |
| MX (1) | MX2022005677A (enExample) |
| WO (1) | WO2021094746A1 (enExample) |
| ZA (1) | ZA202205093B (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108998406B (zh) * | 2018-08-03 | 2022-05-10 | 福州大学 | 一种人类原代培养细胞基因组编辑、定点基因敲入方法 |
| GB201916379D0 (en) | 2019-11-11 | 2019-12-25 | Biocrucible Ltd | Biochemical reaction methods and reagents |
| CN113355389B (zh) * | 2020-03-05 | 2022-11-15 | 广西扬翔股份有限公司 | 利用CRISPR/Cas12a系统靶向富集核酸目标区域的方法及其应用 |
| EP3992635A1 (en) | 2020-10-29 | 2022-05-04 | midge medical GmbH | System and a device for detecting a target analyte |
| US20240110221A1 (en) * | 2022-09-30 | 2024-04-04 | Illumina, Inc. | Methods of modulating clustering kinetics |
| CN116251621B (zh) * | 2022-12-13 | 2024-08-23 | 中国科学院基础医学与肿瘤研究所(筹) | 一种提高氯化血红素的过氧化物酶活性的方法 |
| WO2024178628A1 (en) * | 2023-02-28 | 2024-09-06 | Sun Yat-Sen University | Epigenetic editor assisted by phase separation proteins |
| US12612667B1 (en) * | 2023-05-01 | 2026-04-28 | National Technology & Engineering Solutions Of Sandia, Llc | Solid phase recombinase polymerase amplification for human pathogen identification |
| JP2024179837A (ja) * | 2023-06-16 | 2024-12-26 | 国立大学法人 東京大学 | 酵素の検出方法及び酵素の検出キット |
| KR20250022285A (ko) | 2023-08-07 | 2025-02-17 | 포항공과대학교 산학협력단 | 액체-액체 상분리를 통한 scotin 프롤린-풍부 도메인 생체분자 응축물 및 그의 응용 |
| WO2025137528A1 (en) * | 2023-12-20 | 2025-06-26 | Abbott Laboratories | Reducing agent compositions for isothermal amplification of nucleic acids |
| GB2643378A (en) * | 2024-07-15 | 2026-02-18 | Biocrucible Ltd | Reagents and methods |
| WO2026131829A1 (en) | 2024-12-16 | 2026-06-25 | Neoenta LLC | Devices for analysis of a biological sample and manufacturing methods thereof, and methods of anaylsis of a biological sample |
| GB202500508D0 (en) | 2025-01-15 | 2025-02-26 | Biocrucible Ltd | Molecular diagnostic device |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7399590B2 (en) * | 2002-02-21 | 2008-07-15 | Asm Scientific, Inc. | Recombinase polymerase amplification |
| DK1499738T3 (da) | 2002-02-21 | 2008-11-17 | Asm Scient Inc | Recombinase-polymerease-amplifikation |
| CA2560758A1 (en) | 2004-04-21 | 2005-11-03 | Toray Industries, Inc. | Lab-on-chip substrate |
| DE102005052752A1 (de) | 2005-11-04 | 2007-05-10 | Clondiag Chip Technologies Gmbh | Vorrichtung und Verfahren zum Nachweis von molekularen Wechselwirkungen |
| EP2829615B1 (en) | 2005-07-25 | 2018-05-09 | Alere San Diego, Inc. | Kit for multiplexing recombinase polymerase amplification |
| US20070059713A1 (en) | 2005-09-09 | 2007-03-15 | Lee Jun E | SSB-DNA polymerase fusion proteins |
| EP2029782B1 (en) | 2006-05-04 | 2014-11-26 | Alere San Diego, Inc. | Recombinase polymerase amplification |
| WO2008108927A2 (en) * | 2007-03-06 | 2008-09-12 | Regenerx Biopharmaceuticals, Inc. | Methods and compositions for stabilizing polypeptides |
| CA2946024C (en) | 2007-05-03 | 2020-06-02 | Clondiag Gmbh | Devices and methods for detecting analytes |
| US8560130B2 (en) | 2007-12-04 | 2013-10-15 | Lester F. Ludwig | Software controlled lab-on-a-chip emulation |
| CN102026725B (zh) | 2008-03-14 | 2014-10-29 | 科隆迪亚戈有限公司 | 一种用于检测样品中分析物的装置及其方法 |
| WO2010141940A1 (en) | 2009-06-05 | 2010-12-09 | Alere San Diego, Inc. | Recombinase polymerase amplification reagents and kits |
| KR20120093882A (ko) | 2009-09-16 | 2012-08-23 | 마쎄이 유니버시티 | 융합 폴리펩티드 및 이들의 용도 |
| JP6490576B2 (ja) | 2012-04-12 | 2019-03-27 | ニユー・イングランド・バイオレイブス・インコーポレイテツド | 重合反応のための合成核酸 |
| US10533167B2 (en) | 2016-06-09 | 2020-01-14 | The Trustees Of Princeton University | Optogenetic tool for rapid and reversible clustering of proteins |
| WO2018100408A1 (en) * | 2016-11-30 | 2018-06-07 | Sasinapas Co.,Ltd. | Modified peptides |
| EP3743435B1 (en) | 2018-01-24 | 2023-08-09 | The Trustees Of Princeton University | System and method for inducing clusters of gene regulatory proteins targeted to specific genomic loci |
| GB201916379D0 (en) | 2019-11-11 | 2019-12-25 | Biocrucible Ltd | Biochemical reaction methods and reagents |
-
2019
- 2019-11-11 GB GBGB1916379.9A patent/GB201916379D0/en not_active Ceased
-
2020
- 2020-11-11 WO PCT/GB2020/052866 patent/WO2021094746A1/en not_active Ceased
- 2020-11-11 CN CN202080092644.1A patent/CN114945682A/zh active Pending
- 2020-11-11 BR BR112022009072A patent/BR112022009072A2/pt not_active IP Right Cessation
- 2020-11-11 MX MX2022005677A patent/MX2022005677A/es unknown
- 2020-11-11 AU AU2020382121A patent/AU2020382121B2/en active Active
- 2020-11-11 IL IL292885A patent/IL292885A/en unknown
- 2020-11-11 JP JP2022553222A patent/JP7840266B2/ja active Active
- 2020-11-11 CA CA3157435A patent/CA3157435A1/en active Pending
- 2020-11-11 KR KR1020227019839A patent/KR20220113948A/ko active Pending
- 2020-11-11 EP EP20817468.0A patent/EP4058599A1/en active Pending
-
2021
- 2021-11-17 US US17/528,967 patent/US12618102B2/en active Active
- 2021-11-19 US US17/531,349 patent/US11807899B2/en active Active
-
2022
- 2022-05-09 ZA ZA2022/05093A patent/ZA202205093B/en unknown
-
2025
- 2025-11-28 JP JP2025207502A patent/JP2026041819A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| GB201916379D0 (en) | 2019-12-25 |
| AU2020382121A1 (en) | 2022-06-16 |
| AU2020382121B2 (en) | 2026-06-18 |
| JP7840266B2 (ja) | 2026-04-03 |
| CA3157435A1 (en) | 2021-05-20 |
| MX2022005677A (es) | 2022-09-07 |
| CN114945682A (zh) | 2022-08-26 |
| JP2023501002A (ja) | 2023-01-17 |
| AU2020382121A8 (en) | 2022-07-28 |
| JP2026041819A (ja) | 2026-03-10 |
| US20220112547A1 (en) | 2022-04-14 |
| EP4058599A1 (en) | 2022-09-21 |
| BR112022009072A2 (pt) | 2022-07-26 |
| US11807899B2 (en) | 2023-11-07 |
| KR20220113948A (ko) | 2022-08-17 |
| ZA202205093B (en) | 2024-10-30 |
| WO2021094746A1 (en) | 2021-05-20 |
| US20220145378A1 (en) | 2022-05-12 |
| US12618102B2 (en) | 2026-05-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US12618102B2 (en) | Biochemical reaction methods and reagents comprising intrinsically disordered regions | |
| JP6626848B2 (ja) | 単一の管を付加したプロトコルを用いるタグ化核酸ライブラリの調製 | |
| US9475054B2 (en) | Isolation of polymerase-nucleic acid complexes | |
| CA2751470C (en) | Template-independent ligation of single-stranded dna | |
| EP3218467A1 (en) | Bio-engineered hyper-functional "super" helicases | |
| JP2004508834A (ja) | 定方向進化方法 | |
| JP2008500831A5 (enExample) | ||
| US20150275285A1 (en) | Compositions and methods of nucleic acid preparation and analyses | |
| EP3303584A1 (en) | Methods of analyzing nucleic acids | |
| CN112292460A (zh) | 核酸扩增方法 | |
| HK40034054B (en) | Library preparation of tagged nucleic acid using single tube add-on protocol | |
| HK1231918B (en) | Library preparation of tagged nucleic acid using single tube add-on protocol | |
| HK1231918A1 (en) | Library preparation of tagged nucleic acid using single tube add-on protocol |