MX2021010683A - Esketamina para el tratamiento de la depresión. - Google Patents
Esketamina para el tratamiento de la depresión.Info
- Publication number
- MX2021010683A MX2021010683A MX2021010683A MX2021010683A MX2021010683A MX 2021010683 A MX2021010683 A MX 2021010683A MX 2021010683 A MX2021010683 A MX 2021010683A MX 2021010683 A MX2021010683 A MX 2021010683A MX 2021010683 A MX2021010683 A MX 2021010683A
- Authority
- MX
- Mexico
- Prior art keywords
- esketamine
- depression
- treatment
- methods
- patient
- Prior art date
Links
- YQEZLKZALYSWHR-ZDUSSCGKSA-N (S)-ketamine Chemical compound C=1C=CC=C(Cl)C=1[C@@]1(NC)CCCCC1=O YQEZLKZALYSWHR-ZDUSSCGKSA-N 0.000 title abstract 5
- 229960000450 esketamine Drugs 0.000 title abstract 5
- 208000020401 Depressive disease Diseases 0.000 title 1
- 238000000034 method Methods 0.000 abstract 3
- 208000028552 Treatment-Resistant Depressive disease Diseases 0.000 abstract 1
- 229940126534 drug product Drugs 0.000 abstract 1
- 208000024714 major depressive disease Diseases 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Otolaryngology (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962814274P | 2019-03-05 | 2019-03-05 | |
| US201962813767P | 2019-03-05 | 2019-03-05 | |
| PCT/IB2020/051344 WO2020178653A1 (en) | 2019-03-05 | 2020-02-18 | Esketamine for the treatment of depression |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2021010683A true MX2021010683A (es) | 2021-12-10 |
Family
ID=72338604
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2021010683A MX2021010683A (es) | 2019-03-05 | 2020-02-18 | Esketamina para el tratamiento de la depresión. |
Country Status (11)
| Country | Link |
|---|---|
| US (4) | US20230117657A1 (enExample) |
| EP (1) | EP3934632A4 (enExample) |
| JP (2) | JP2022524008A (enExample) |
| CN (1) | CN114126595A (enExample) |
| AU (1) | AU2020231172A1 (enExample) |
| BR (1) | BR112021017457A2 (enExample) |
| CA (1) | CA3131929A1 (enExample) |
| IL (2) | IL318198A (enExample) |
| MA (1) | MA55218A (enExample) |
| MX (1) | MX2021010683A (enExample) |
| WO (1) | WO2020178653A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK3505157T3 (da) | 2017-12-29 | 2022-02-28 | Celon Pharma Sa | Tørpulver-ketaminsammensætning til pulmonal indgivelse ved behandlingsresistent depression |
| EP3934632A4 (en) * | 2019-03-05 | 2022-11-23 | Janssen Pharmaceuticals, Inc. | Esketamine for the treatment of depression |
| CN115135363A (zh) * | 2019-09-13 | 2022-09-30 | 杨森制药公司 | 艾司氯胺酮的鼻内施用 |
| PH12022551856A1 (en) | 2020-01-22 | 2024-01-03 | Seelos Therapeutics Inc | Reducing side effects of nmda antagonists |
| CN116744922A (zh) * | 2020-12-04 | 2023-09-12 | 诺华股份有限公司 | Nr2b-nmda受体nam在治疗抑郁症中的剂量方案 |
| US20240261236A1 (en) * | 2021-05-14 | 2024-08-08 | Seelos Therapeutics, Inc. | Methods of using nmda receptor antagonists |
| IL321485A (en) * | 2022-12-14 | 2025-08-01 | Luminous Mind Inc | Treatment of psychological symptoms affecting other medical conditions (PFAOMC) |
| EP4687860A1 (en) * | 2023-03-24 | 2026-02-11 | Janssen Pharmaceutica NV | Esketamine for use in the treatment of depression |
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| CH535201A (de) | 1969-12-19 | 1973-03-31 | Bristol Myers Co | Verfahren zur Spaltung von racemischen 2-(o-Chlorphenyl)-2-methylaminocyclohexanon in die optisch-aktiven Isomeren |
| JPS632932A (ja) | 1986-06-23 | 1988-01-07 | Teijin Ltd | 経鼻投与用粉末状組成物 |
| US5002935A (en) | 1987-12-30 | 1991-03-26 | University Of Florida | Improvements in redox systems for brain-targeted drug delivery |
| US4994467A (en) | 1989-05-31 | 1991-02-19 | Zimmerman Andrew W | Treating autism and other developmental disorders in children with NMDA receptor antagonists |
| DE4312016A1 (de) | 1993-04-13 | 1994-10-20 | Goedecke Ag | Stabile Ketamin-Lösungen |
| US5543434A (en) | 1994-02-25 | 1996-08-06 | Weg; Stuart L. | Nasal administration of ketamine to manage pain |
| DK0814790T3 (da) | 1995-02-24 | 2003-11-10 | Stuart L Weg | Indgivelse af ketamin med henblik på afgiftning |
| WO1997007750A1 (en) | 1995-08-30 | 1997-03-06 | Weg Stuart L | Administration of ketamine to manage pain and to reduce drug dependency |
| FR2739294B1 (fr) | 1995-09-29 | 1998-01-16 | Lhd Lab Hygiene Dietetique | Embout nasal de securite |
| DE19619665C2 (de) | 1996-05-15 | 2001-03-08 | Goedecke Ag | Racemattrennung von Ketamin |
| DE19723133A1 (de) | 1997-06-03 | 1998-12-10 | Caideil M P Teoranta Tourmakea | Austragvorrichtung für Medien |
| FR2764807B1 (fr) | 1997-06-18 | 1999-08-20 | Valois Sa | Dispositif de distribution nasale d'un produit fluide ou pulverulent |
| CA2338457C (en) | 1998-07-24 | 2009-11-17 | Seo Hong Yoo | Preparation of aqueous clear solution dosage forms with bile acids |
| US6599883B1 (en) | 1998-10-30 | 2003-07-29 | Nastech Pharmaceutical Company, Inc. | Nasal delivery of xylitol |
| US6176242B1 (en) | 1999-04-30 | 2001-01-23 | Medtronic Inc | Method of treating manic depression by brain infusion |
| US6017961A (en) | 1999-07-08 | 2000-01-25 | Flores; John Anthony | Ketamine and n-butyl-p-aminobezoate in PLO |
| EP1103256A1 (de) | 1999-11-26 | 2001-05-30 | Claudius Dr. med. Böck | Verwendung von Ketamin zur Behandlung von neuroendokriner Immundysfunktion und algogenem Psychosyndrom |
| US6572849B2 (en) | 2000-09-20 | 2003-06-03 | Lee Shahinian, Jr. | Self-preserved antibacterial nasal, inhalable, and topical ophthalmic preparations and medications |
| US6881731B1 (en) | 2000-10-23 | 2005-04-19 | Shanbrom Technologies, Llc | Enhancers for microbiological disinfection |
| EP1551393A4 (en) | 2002-07-30 | 2010-06-16 | Peter Migaly | COMBINATION OF THERAPY FOR DEPRESSION, PREVENTION OF SUICIDE AND VARIOUS MEDICAL AND PSYCHIATRIC DISORDERS |
| US7273889B2 (en) | 2002-09-25 | 2007-09-25 | Innovative Drug Delivery Systems, Inc. | NMDA receptor antagonist formulation with reduced neurotoxicity |
| JP2006510618A (ja) | 2002-11-18 | 2006-03-30 | ヤウポン セラピューティクス,インコーポレーテッド | ノルケタミンおよびケタミン/ノルケタミンプロドラッグの鎮痛的使用 |
| US7687080B2 (en) | 2002-11-25 | 2010-03-30 | Taraxos Inc. | Treatment of neuropathy |
| US20040214215A1 (en) | 2003-03-07 | 2004-10-28 | Yu Ruey J. | Bioavailability and improved delivery of alkaline pharmaceutical drugs |
| US8082173B2 (en) * | 2003-05-22 | 2011-12-20 | Cecil Kost | Drug sample fulfillment architecture |
| US20040265364A1 (en) | 2003-06-25 | 2004-12-30 | Binnur Ozturk | Neuropathy cream |
| US20050095277A1 (en) | 2003-06-25 | 2005-05-05 | Binnur Ozturk | Neuropathy cream |
| WO2005079756A2 (en) | 2004-02-13 | 2005-09-01 | Neuromolecular, Inc. | Combination of a nmda receptor antagonist and an anti-depressive drug mao-inhibitor or a gadph-inhibitor for the treatment of psychiatric conditions |
| PL2486942T3 (pl) | 2004-11-24 | 2019-05-31 | Meda Pharmaceuticals Inc | Kompozycje zawierające azelastynę oraz sposoby ich stosowania |
| US20060223788A1 (en) | 2005-03-29 | 2006-10-05 | Cathcart Clifton H | Analgesic composition for topical use |
| EP2526987A3 (en) | 2005-06-01 | 2013-04-24 | SHL Group AB | Device for delivering medicament |
| US20060276550A1 (en) | 2005-06-03 | 2006-12-07 | Dileep Bhagwat | Topical compositions of ketamine and butamben and methods of their use |
| JP2009530385A (ja) * | 2006-03-22 | 2009-08-27 | マウント シナイ スクール オブ メディシン | うつ病の治療のためのケタミンの鼻内投与 |
| US20070256688A1 (en) | 2006-04-21 | 2007-11-08 | Aradigm Corporation | Mechanical single dose intrapulmonary drug delivery devices |
| EP2029136A4 (en) | 2006-05-22 | 2010-01-06 | Vanda Pharmaceuticals Inc | TREATMENT FOR DEPRESSION DISEASES |
| DE102007009888A1 (de) | 2007-02-28 | 2008-09-04 | Hermann, Holger Lars, Dr. | Verwendung von S-(+)-Ketamin zur Behandlung von Depressionen |
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| WO2008151179A2 (en) * | 2007-06-04 | 2008-12-11 | Auspex Pharmaceuticals, Inc. | Substituted phenethylamines |
| WO2009131794A1 (en) | 2008-03-27 | 2009-10-29 | University Of Kentucky Research Foundation | Opioid-ketamine and norketamine codrug combinations for pain management |
| EP2303308A4 (en) | 2008-05-13 | 2012-11-07 | Clarassance Inc | HUMAN RECOMBINANT PROTEIN CC10 AND COMPOSITIONS CONTAINING IT FOR THE TREATMENT OF NASAL RHINITIS |
| US20110038807A1 (en) | 2009-08-14 | 2011-02-17 | Demitri Papolos | Compositions and methods for treating bipolar disorder |
| US20120225949A1 (en) | 2009-08-14 | 2012-09-06 | Demitri Papalos | Compositions and methods for treating bipolar disorder |
| AU2011267474B2 (en) | 2010-06-15 | 2016-05-26 | Grünenthal GmbH | Pharmaceutical combination for the treatment of pain |
| WO2013003669A2 (en) | 2011-06-30 | 2013-01-03 | University Of South Florida | Compositions, methods of use, and methods of treatment |
| JP6296985B2 (ja) | 2011-10-14 | 2018-03-20 | ザ ユナイテッド ステイツ オブ アメリカ, アズ リプレゼンテッド バイ ザ セクレタリー, デパートメント オブ ヘルス アンド ヒューマン サービシーズ | うつ病及び神経障害性疼痛の治療における(2r,6r)−ヒドロキシノルケタミン、(s)−デヒドロノルケタミン及び他の(r,s)−ケタミンの立体異性デヒドロ及びヒドロキシル化代謝生成物の使用 |
| CN104053785A (zh) | 2011-11-14 | 2014-09-17 | 综合医院公司 | 为患有抑郁症的受试者选择治疗方案的测定法和方法 |
| US20130209585A1 (en) | 2012-02-13 | 2013-08-15 | Stanley Kim | Topical NMDA Antagonist Formulations for the Treatment of Peripheral Neuropathy |
| WO2013138322A1 (en) * | 2012-03-12 | 2013-09-19 | Janssen Pharmaceutica Nv | Esketamine for the treatment of treatment-refractory or treatment-resistant depression |
| AU2016203771A1 (en) | 2012-03-13 | 2016-06-23 | Janssen Pharmaceutica Nv | Esketamine for the treatment of treatment-refractory or treatment-resistant depression |
| JP2015512418A (ja) | 2012-03-30 | 2015-04-27 | ザ ジェネラル ホスピタル コーポレイション | うつ病の治療におけるスコポラミンおよびケタミンを含む組成物 |
| US20140079740A1 (en) | 2012-08-02 | 2014-03-20 | ClinPharm Support GmbH | Oral transmucosal adminstration forms of s-ketamine |
| MX2015002378A (es) | 2012-08-23 | 2015-09-25 | Stuart L Weg | Composicion ansiolitica, formulacion y metodo de uso. |
| FR2994844B1 (fr) | 2012-08-31 | 2015-01-02 | Assist Publ Hopitaux De Paris | Formulation gelifiante a base de ketamine |
| NZ619257A (en) | 2012-10-08 | 2015-07-31 | Auckland Uniservices Ltd | Ketamine derivatives |
| ES2484068B1 (es) | 2013-02-08 | 2015-04-16 | Ana MÍNGUEZ MARTÍ | Una composición farmacéutica que contiene ketamina y amitriptilina |
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| KR20220044380A (ko) | 2013-04-12 | 2022-04-07 | 이칸 스쿨 오브 메디슨 엣 마운트 시나이 | 외상후 스트레스 장애의 치료 방법 |
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| EP3272338B1 (en) | 2014-04-17 | 2020-09-09 | Develco Pharma Schweiz AG | Oral dosage form of ketamine |
| PE20211759A1 (es) | 2014-05-04 | 2021-09-07 | Firmenich & Cie | Formulacion edulcorante con naringenina |
| FR3023188B1 (fr) | 2014-07-04 | 2016-08-19 | Aptar France Sas | Dispositif de distribution de produit fluide. |
| US10098854B2 (en) | 2014-08-13 | 2018-10-16 | Janssen Pharmaceutica Nv | Method for the treatment of depression |
| EP3193853A1 (en) | 2014-09-15 | 2017-07-26 | Janssen Pharmaceutica NV | VAL66MET (SNP rs6265) GENOTYPE SPECIFIC DOSING REGIMENS AND METHODS FOR THE TREATMENT OF DEPRESSION |
| WO2016109427A1 (en) | 2014-12-31 | 2016-07-07 | Icahn School Of Medicine At Mount Sinai | Method of maintaining the anti-depressant effect of ketamine with lithium |
| WO2016172672A1 (en) | 2015-04-24 | 2016-10-27 | Icahn School Of Medicine At Mount Sinai | Method for treating suicidal ideation |
| CN104798728A (zh) | 2015-05-08 | 2015-07-29 | 南京中医药大学 | 产后抑郁动物模型的建立方法及其应用 |
| US20160332962A1 (en) | 2015-05-13 | 2016-11-17 | Janssen Pharmaceutica Nv | (s)-csa salt of s-ketamine, (r)-csa salt of s-ketamine and processes for the preparation of s-ketamine |
| US20160338977A1 (en) * | 2015-05-20 | 2016-11-24 | Janssen Pharmaceutica Nv | Methods and kits for treating depression |
| CN107847469A (zh) | 2015-06-27 | 2018-03-27 | 美国神农制药责任有限公司 | 氯胺酮透皮递送系统 |
| US20180296478A1 (en) | 2016-02-12 | 2018-10-18 | Synergistic Therapeutics, Llc | Sublingual antidepressant and antianxiety tablet |
| US20180042936A1 (en) | 2016-03-18 | 2018-02-15 | Genomind, Inc. | Maintenance therapy using tianeptine |
| SG11202005896WA (en) * | 2017-12-22 | 2020-07-29 | Janssen Pharmaceuticals Inc | Esketamine for the treatment of depression |
| EP3934632A4 (en) * | 2019-03-05 | 2022-11-23 | Janssen Pharmaceuticals, Inc. | Esketamine for the treatment of depression |
-
2020
- 2020-02-18 EP EP20766782.5A patent/EP3934632A4/en not_active Withdrawn
- 2020-02-18 IL IL318198A patent/IL318198A/en unknown
- 2020-02-18 BR BR112021017457A patent/BR112021017457A2/pt not_active Application Discontinuation
- 2020-02-18 CA CA3131929A patent/CA3131929A1/en active Pending
- 2020-02-18 CN CN202080034094.8A patent/CN114126595A/zh active Pending
- 2020-02-18 MX MX2021010683A patent/MX2021010683A/es unknown
- 2020-02-18 WO PCT/IB2020/051344 patent/WO2020178653A1/en not_active Ceased
- 2020-02-18 MA MA055218A patent/MA55218A/fr unknown
- 2020-02-18 US US17/436,188 patent/US20230117657A1/en not_active Abandoned
- 2020-02-18 JP JP2021552724A patent/JP2022524008A/ja not_active Withdrawn
- 2020-02-18 AU AU2020231172A patent/AU2020231172A1/en not_active Abandoned
-
2021
- 2021-08-31 IL IL286000A patent/IL286000A/en unknown
-
2022
- 2022-04-01 US US17/711,277 patent/US11883526B2/en active Active
-
2024
- 2024-04-23 US US18/643,034 patent/US20240277608A1/en not_active Abandoned
- 2024-05-31 US US18/680,287 patent/US20240325296A1/en not_active Abandoned
- 2024-09-12 JP JP2024157984A patent/JP2025003983A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2025003983A (ja) | 2025-01-14 |
| IL318198A (en) | 2025-03-01 |
| WO2020178653A1 (en) | 2020-09-10 |
| US20220362144A1 (en) | 2022-11-17 |
| US20240325296A1 (en) | 2024-10-03 |
| CA3131929A1 (en) | 2020-09-10 |
| AU2020231172A1 (en) | 2021-09-23 |
| US20240277608A1 (en) | 2024-08-22 |
| MA55218A (fr) | 2022-01-12 |
| US20230117657A1 (en) | 2023-04-20 |
| JP2022524008A (ja) | 2022-04-27 |
| IL286000A (en) | 2021-10-31 |
| BR112021017457A2 (pt) | 2021-11-16 |
| EP3934632A4 (en) | 2022-11-23 |
| EP3934632A1 (en) | 2022-01-12 |
| CN114126595A (zh) | 2022-03-01 |
| US11883526B2 (en) | 2024-01-30 |
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