MX2021010683A - Esketamina para el tratamiento de la depresión. - Google Patents
Esketamina para el tratamiento de la depresión.Info
- Publication number
- MX2021010683A MX2021010683A MX2021010683A MX2021010683A MX2021010683A MX 2021010683 A MX2021010683 A MX 2021010683A MX 2021010683 A MX2021010683 A MX 2021010683A MX 2021010683 A MX2021010683 A MX 2021010683A MX 2021010683 A MX2021010683 A MX 2021010683A
- Authority
- MX
- Mexico
- Prior art keywords
- esketamine
- depression
- treatment
- methods
- patient
- Prior art date
Links
- YQEZLKZALYSWHR-ZDUSSCGKSA-N (S)-ketamine Chemical compound C=1C=CC=C(Cl)C=1[C@@]1(NC)CCCCC1=O YQEZLKZALYSWHR-ZDUSSCGKSA-N 0.000 title abstract 5
- 229960000450 esketamine Drugs 0.000 title abstract 5
- 208000020401 Depressive disease Diseases 0.000 title 1
- 238000000034 method Methods 0.000 abstract 3
- 208000028552 Treatment-Resistant Depressive disease Diseases 0.000 abstract 1
- 229940126534 drug product Drugs 0.000 abstract 1
- 208000024714 major depressive disease Diseases 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Otolaryngology (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962814274P | 2019-03-05 | 2019-03-05 | |
| US201962813767P | 2019-03-05 | 2019-03-05 | |
| PCT/IB2020/051344 WO2020178653A1 (en) | 2019-03-05 | 2020-02-18 | Esketamine for the treatment of depression |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2021010683A true MX2021010683A (es) | 2021-12-10 |
Family
ID=72338604
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2021010683A MX2021010683A (es) | 2019-03-05 | 2020-02-18 | Esketamina para el tratamiento de la depresión. |
Country Status (11)
| Country | Link |
|---|---|
| US (4) | US20230117657A1 (enExample) |
| EP (1) | EP3934632A4 (enExample) |
| JP (2) | JP2022524008A (enExample) |
| CN (1) | CN114126595A (enExample) |
| AU (1) | AU2020231172A1 (enExample) |
| BR (1) | BR112021017457A2 (enExample) |
| CA (1) | CA3131929A1 (enExample) |
| IL (2) | IL318198A (enExample) |
| MA (1) | MA55218A (enExample) |
| MX (1) | MX2021010683A (enExample) |
| WO (1) | WO2020178653A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2907692T3 (es) | 2017-12-29 | 2022-04-26 | Celon Pharma Sa | Composición de ketamina de polvo seco para su administración por vía pulmonar en la depresión resistente al tratamiento |
| JP2022524008A (ja) * | 2019-03-05 | 2022-04-27 | ヤンセン ファーマシューティカルズ,インコーポレーテッド | うつ病の治療のためのエスケタミン |
| JP2022548233A (ja) * | 2019-09-13 | 2022-11-17 | ヤンセン ファーマシューティカルズ,インコーポレーテッド | エスケタミンの鼻腔内投与 |
| JP2023511370A (ja) * | 2020-01-22 | 2023-03-17 | シーロス セラピューティクス, インコーポレイテッド | Nmda拮抗薬の副作用の低減 |
| CN116744922A (zh) * | 2020-12-04 | 2023-09-12 | 诺华股份有限公司 | Nr2b-nmda受体nam在治疗抑郁症中的剂量方案 |
| US20240261236A1 (en) * | 2021-05-14 | 2024-08-08 | Seelos Therapeutics, Inc. | Methods of using nmda receptor antagonists |
| IL321485A (en) * | 2022-12-14 | 2025-08-01 | Luminous Mind Inc | Treatment of psychological symptoms affecting other medical conditions (PFAOMC) |
| EP4687860A1 (en) * | 2023-03-24 | 2026-02-11 | Janssen Pharmaceutica NV | Esketamine for use in the treatment of depression |
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| CH535201A (de) | 1969-12-19 | 1973-03-31 | Bristol Myers Co | Verfahren zur Spaltung von racemischen 2-(o-Chlorphenyl)-2-methylaminocyclohexanon in die optisch-aktiven Isomeren |
| JPS632932A (ja) | 1986-06-23 | 1988-01-07 | Teijin Ltd | 経鼻投与用粉末状組成物 |
| US5002935A (en) | 1987-12-30 | 1991-03-26 | University Of Florida | Improvements in redox systems for brain-targeted drug delivery |
| US4994467A (en) | 1989-05-31 | 1991-02-19 | Zimmerman Andrew W | Treating autism and other developmental disorders in children with NMDA receptor antagonists |
| DE4312016A1 (de) | 1993-04-13 | 1994-10-20 | Goedecke Ag | Stabile Ketamin-Lösungen |
| US5543434A (en) | 1994-02-25 | 1996-08-06 | Weg; Stuart L. | Nasal administration of ketamine to manage pain |
| DK0814790T3 (da) | 1995-02-24 | 2003-11-10 | Stuart L Weg | Indgivelse af ketamin med henblik på afgiftning |
| CA2230690C (en) | 1995-08-30 | 2008-12-23 | Stuart L. Weg | Administration of ketamine to manage pain and to reduce drug dependency |
| FR2739294B1 (fr) | 1995-09-29 | 1998-01-16 | Lhd Lab Hygiene Dietetique | Embout nasal de securite |
| DE19619665C2 (de) | 1996-05-15 | 2001-03-08 | Goedecke Ag | Racemattrennung von Ketamin |
| DE19723133A1 (de) | 1997-06-03 | 1998-12-10 | Caideil M P Teoranta Tourmakea | Austragvorrichtung für Medien |
| FR2764807B1 (fr) | 1997-06-18 | 1999-08-20 | Valois Sa | Dispositif de distribution nasale d'un produit fluide ou pulverulent |
| RU2224523C2 (ru) | 1998-07-24 | 2004-02-27 | Сео Хонг Ю | Водный раствор, содержащий желчную кислоту, и способ его получения |
| US6599883B1 (en) | 1998-10-30 | 2003-07-29 | Nastech Pharmaceutical Company, Inc. | Nasal delivery of xylitol |
| US6176242B1 (en) | 1999-04-30 | 2001-01-23 | Medtronic Inc | Method of treating manic depression by brain infusion |
| US6017961A (en) | 1999-07-08 | 2000-01-25 | Flores; John Anthony | Ketamine and n-butyl-p-aminobezoate in PLO |
| EP1103256A1 (de) | 1999-11-26 | 2001-05-30 | Claudius Dr. med. Böck | Verwendung von Ketamin zur Behandlung von neuroendokriner Immundysfunktion und algogenem Psychosyndrom |
| EP1328214A4 (en) | 2000-09-20 | 2009-07-29 | Shahinian Lee Jr | NASAL, INHALABLE AND LOCAL OPHTHALMIC PREPARATIONS AND MEDICATIONS WITH SPONTANEOUS CONSERVATION |
| US6881731B1 (en) | 2000-10-23 | 2005-04-19 | Shanbrom Technologies, Llc | Enhancers for microbiological disinfection |
| CA2529857A1 (en) | 2002-07-30 | 2004-02-05 | Peter Migaly | Combination therapy for depression, prevention of suicide, and varous medical and psychiatric conditions |
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| JP2006510618A (ja) | 2002-11-18 | 2006-03-30 | ヤウポン セラピューティクス,インコーポレーテッド | ノルケタミンおよびケタミン/ノルケタミンプロドラッグの鎮痛的使用 |
| US7687080B2 (en) | 2002-11-25 | 2010-03-30 | Taraxos Inc. | Treatment of neuropathy |
| US20040214215A1 (en) | 2003-03-07 | 2004-10-28 | Yu Ruey J. | Bioavailability and improved delivery of alkaline pharmaceutical drugs |
| US8082173B2 (en) * | 2003-05-22 | 2011-12-20 | Cecil Kost | Drug sample fulfillment architecture |
| US20050095277A1 (en) | 2003-06-25 | 2005-05-05 | Binnur Ozturk | Neuropathy cream |
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| WO2005079756A2 (en) | 2004-02-13 | 2005-09-01 | Neuromolecular, Inc. | Combination of a nmda receptor antagonist and an anti-depressive drug mao-inhibitor or a gadph-inhibitor for the treatment of psychiatric conditions |
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| US20060223788A1 (en) | 2005-03-29 | 2006-10-05 | Cathcart Clifton H | Analgesic composition for topical use |
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| US20060276550A1 (en) | 2005-06-03 | 2006-12-07 | Dileep Bhagwat | Topical compositions of ketamine and butamben and methods of their use |
| AU2007229866A1 (en) | 2006-03-22 | 2007-10-04 | Mount Sinai School Of Medicine | Intranasal administration of ketamine to treat depression |
| WO2007123945A2 (en) | 2006-04-21 | 2007-11-01 | Aradigm Corporation | Mechanical single dose intrapulmonary drug delivery devices |
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| DE102007009888A1 (de) | 2007-02-28 | 2008-09-04 | Hermann, Holger Lars, Dr. | Verwendung von S-(+)-Ketamin zur Behandlung von Depressionen |
| BRPI0809843A2 (pt) | 2007-04-26 | 2014-09-23 | Auspex Pharmaceuticals Inc | "composto, composição farmacêutica e uso de um composto" |
| US7745665B2 (en) * | 2007-06-04 | 2010-06-29 | Auspex Pharmaceuticals, Inc. | Substituted phenethylamines |
| WO2009131794A1 (en) | 2008-03-27 | 2009-10-29 | University Of Kentucky Research Foundation | Opioid-ketamine and norketamine codrug combinations for pain management |
| NZ588895A (en) | 2008-05-13 | 2012-07-27 | Clarassance Inc | Recombinant human CC10 (rhCC10 aka uteroglobin) and compositions thereof for use in the treatment of nasal rhinitis |
| US20110038807A1 (en) | 2009-08-14 | 2011-02-17 | Demitri Papolos | Compositions and methods for treating bipolar disorder |
| US20120225949A1 (en) | 2009-08-14 | 2012-09-06 | Demitri Papalos | Compositions and methods for treating bipolar disorder |
| EP2992877A1 (en) | 2010-06-15 | 2016-03-09 | Grünenthal GmbH | Pharmaceutical combination for the treatment of pain |
| WO2013003669A2 (en) | 2011-06-30 | 2013-01-03 | University Of South Florida | Compositions, methods of use, and methods of treatment |
| WO2013056229A1 (en) | 2011-10-14 | 2013-04-18 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | The use of (2r, 6r)-hydroxynorketamine, (s)-dehydronorketamine and other stereoisomeric dehydro and hydroxylated metabolites of (r,s)- ketamine in the treatment of depression and neuropathic pain |
| RU2622082C2 (ru) | 2011-11-14 | 2017-06-09 | Нестек С.А. | Анализы и способы выбора режима лечения пациента с депрессией |
| US20130209585A1 (en) | 2012-02-13 | 2013-08-15 | Stanley Kim | Topical NMDA Antagonist Formulations for the Treatment of Peripheral Neuropathy |
| WO2013138322A1 (en) * | 2012-03-12 | 2013-09-19 | Janssen Pharmaceutica Nv | Esketamine for the treatment of treatment-refractory or treatment-resistant depression |
| AU2016203771A1 (en) | 2012-03-13 | 2016-06-23 | Janssen Pharmaceutica Nv | Esketamine for the treatment of treatment-refractory or treatment-resistant depression |
| EP2830604A4 (en) | 2012-03-30 | 2015-08-19 | Gen Hospital Corp | COMPOSITIONS WITH SCOPOLAMINE AND KETAMINE FOR THE TREATMENT OF DEPRESSIONS |
| US20140079740A1 (en) | 2012-08-02 | 2014-03-20 | ClinPharm Support GmbH | Oral transmucosal adminstration forms of s-ketamine |
| KR20150096370A (ko) | 2012-08-23 | 2015-08-24 | 스튜어트 엘. 웨그 | 항불안제 조성물, 제형 및 사용방법 |
| FR2994844B1 (fr) | 2012-08-31 | 2015-01-02 | Assist Publ Hopitaux De Paris | Formulation gelifiante a base de ketamine |
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| HUE056378T2 (hu) | 2013-09-13 | 2022-02-28 | Univ Chiba Nat Univ Corp | R-Ketamin és sójának alkalmazása gyógyszerekként |
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| EP3094312B1 (en) | 2014-01-14 | 2019-03-13 | Children's Hospital Medical Center | Compositions comprising ketamine for treating an autism spectrum disorder |
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| MX2016013787A (es) | 2014-05-04 | 2017-07-24 | Firmenich & Cie | Productos alimenticios y bebidas que estan saborizados. |
| FR3023188B1 (fr) | 2014-07-04 | 2016-08-19 | Aptar France Sas | Dispositif de distribution de produit fluide. |
| KR20170040800A (ko) | 2014-08-13 | 2017-04-13 | 얀센 파마슈티카 엔.브이. | 우울증 치료 방법 |
| AU2015318123A1 (en) | 2014-09-15 | 2017-03-30 | Janssen Pharmaceutica Nv | Val66Met (SNP rs6265) genotype specific dosing regimens and methods for the treatment of depression |
| WO2016109427A1 (en) | 2014-12-31 | 2016-07-07 | Icahn School Of Medicine At Mount Sinai | Method of maintaining the anti-depressant effect of ketamine with lithium |
| WO2016172672A1 (en) | 2015-04-24 | 2016-10-27 | Icahn School Of Medicine At Mount Sinai | Method for treating suicidal ideation |
| CN104798728A (zh) | 2015-05-08 | 2015-07-29 | 南京中医药大学 | 产后抑郁动物模型的建立方法及其应用 |
| US20160332962A1 (en) | 2015-05-13 | 2016-11-17 | Janssen Pharmaceutica Nv | (s)-csa salt of s-ketamine, (r)-csa salt of s-ketamine and processes for the preparation of s-ketamine |
| US20160338977A1 (en) * | 2015-05-20 | 2016-11-24 | Janssen Pharmaceutica Nv | Methods and kits for treating depression |
| CN107847469A (zh) | 2015-06-27 | 2018-03-27 | 美国神农制药责任有限公司 | 氯胺酮透皮递送系统 |
| US20180296478A1 (en) | 2016-02-12 | 2018-10-18 | Synergistic Therapeutics, Llc | Sublingual antidepressant and antianxiety tablet |
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| KR20240011237A (ko) * | 2017-12-22 | 2024-01-25 | 얀센 파마슈티카 엔브이 | 우울증 치료를 위한 에스케타민 |
| JP2022524008A (ja) * | 2019-03-05 | 2022-04-27 | ヤンセン ファーマシューティカルズ,インコーポレーテッド | うつ病の治療のためのエスケタミン |
-
2020
- 2020-02-18 JP JP2021552724A patent/JP2022524008A/ja not_active Withdrawn
- 2020-02-18 MA MA055218A patent/MA55218A/fr unknown
- 2020-02-18 CA CA3131929A patent/CA3131929A1/en active Pending
- 2020-02-18 CN CN202080034094.8A patent/CN114126595A/zh active Pending
- 2020-02-18 US US17/436,188 patent/US20230117657A1/en not_active Abandoned
- 2020-02-18 AU AU2020231172A patent/AU2020231172A1/en not_active Abandoned
- 2020-02-18 IL IL318198A patent/IL318198A/en unknown
- 2020-02-18 MX MX2021010683A patent/MX2021010683A/es unknown
- 2020-02-18 EP EP20766782.5A patent/EP3934632A4/en not_active Withdrawn
- 2020-02-18 WO PCT/IB2020/051344 patent/WO2020178653A1/en not_active Ceased
- 2020-02-18 BR BR112021017457A patent/BR112021017457A2/pt not_active Application Discontinuation
-
2021
- 2021-08-31 IL IL286000A patent/IL286000A/en unknown
-
2022
- 2022-04-01 US US17/711,277 patent/US11883526B2/en active Active
-
2024
- 2024-04-23 US US18/643,034 patent/US20240277608A1/en not_active Abandoned
- 2024-05-31 US US18/680,287 patent/US20240325296A1/en not_active Abandoned
- 2024-09-12 JP JP2024157984A patent/JP2025003983A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20220362144A1 (en) | 2022-11-17 |
| US11883526B2 (en) | 2024-01-30 |
| CA3131929A1 (en) | 2020-09-10 |
| EP3934632A1 (en) | 2022-01-12 |
| IL286000A (en) | 2021-10-31 |
| US20240325296A1 (en) | 2024-10-03 |
| WO2020178653A1 (en) | 2020-09-10 |
| CN114126595A (zh) | 2022-03-01 |
| EP3934632A4 (en) | 2022-11-23 |
| AU2020231172A1 (en) | 2021-09-23 |
| US20230117657A1 (en) | 2023-04-20 |
| US20240277608A1 (en) | 2024-08-22 |
| JP2022524008A (ja) | 2022-04-27 |
| IL318198A (en) | 2025-03-01 |
| JP2025003983A (ja) | 2025-01-14 |
| BR112021017457A2 (pt) | 2021-11-16 |
| MA55218A (fr) | 2022-01-12 |
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