SG11202005896WA - Esketamine for the treatment of depression - Google Patents

Esketamine for the treatment of depression

Info

Publication number
SG11202005896WA
SG11202005896WA SG11202005896WA SG11202005896WA SG11202005896WA SG 11202005896W A SG11202005896W A SG 11202005896WA SG 11202005896W A SG11202005896W A SG 11202005896WA SG 11202005896W A SG11202005896W A SG 11202005896WA SG 11202005896W A SG11202005896W A SG 11202005896WA
Authority
SG
Singapore
Prior art keywords
esketamine
depression
treatment
Prior art date
Application number
SG11202005896WA
Inventor
Ella Daly
Wayne Drevets
Honglan Li
David Wood Hough
Adam Janik
Rachel Ochs-Ross
Jaskaran Singh
Ewa Wajs
Peter Zannikos
Carla Canuso
Original Assignee
Janssen Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceuticals Inc filed Critical Janssen Pharmaceuticals Inc
Publication of SG11202005896WA publication Critical patent/SG11202005896WA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Otolaryngology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG11202005896WA 2017-12-22 2018-12-18 Esketamine for the treatment of depression SG11202005896WA (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201762609504P 2017-12-22 2017-12-22
US201862663206P 2018-04-26 2018-04-26
US201862663219P 2018-04-26 2018-04-26
US201862667406P 2018-05-04 2018-05-04
US201862675846P 2018-05-24 2018-05-24
US201862755905P 2018-11-05 2018-11-05
PCT/US2018/066143 WO2019126108A1 (en) 2017-12-22 2018-12-18 Esketamine for the treatment of depression

Publications (1)

Publication Number Publication Date
SG11202005896WA true SG11202005896WA (en) 2020-07-29

Family

ID=65003585

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202005896WA SG11202005896WA (en) 2017-12-22 2018-12-18 Esketamine for the treatment of depression

Country Status (16)

Country Link
US (2) US11707440B2 (en)
EP (1) EP3501542A1 (en)
JP (2) JP2021506924A (en)
KR (2) KR20200113197A (en)
CN (2) CN112423789A (en)
AU (1) AU2018282466A1 (en)
BR (1) BR112020012473A2 (en)
CA (1) CA3086478A1 (en)
IL (1) IL275482A (en)
JO (1) JOP20200156A1 (en)
MA (1) MA47719A (en)
MX (2) MX2020006650A (en)
PH (1) PH12020500555A1 (en)
SG (1) SG11202005896WA (en)
TW (2) TWI843711B (en)
WO (1) WO2019126108A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014152196A1 (en) 2013-03-15 2014-09-25 Janssen Pharmaceutica Nv Pharmaceutical composition of s-ketamine hydrochloride
CN107208133A (en) 2014-09-15 2017-09-26 詹森药业有限公司 Val66Met (SNPrs6265) Serotype-dependent dosage regimens and method for treating depression
US20200009081A1 (en) 2017-09-13 2020-01-09 Janssen Pharmaceutica N.V. Delivery Of Esketamine For The Treatment Of Depression
SG11202005896WA (en) 2017-12-22 2020-07-29 Janssen Pharmaceuticals Inc Esketamine for the treatment of depression
EP3813807A1 (en) 2018-06-27 2021-05-05 Clexio Biosciences Ltd. Method of treating major depressive disorder
US11865088B2 (en) 2018-10-05 2024-01-09 Clexio Biosciences Ltd. Method of treating major depressive disorder
MX2021010683A (en) * 2019-03-05 2021-12-10 Janssen Pharmaceuticals Inc Esketamine for the treatment of depression.
AU2020324432A1 (en) * 2019-08-05 2021-10-07 The Ketamine Research Foundation Ketamine for the treatment of postpartum symptoms and disorders
CN114286674A (en) * 2019-08-28 2022-04-05 杨森制药公司 Esketamine for use in the treatment of patients with major depressive disorder including suicidal ideation
AU2020345050A1 (en) * 2019-09-13 2021-09-16 Janssen Pharmaceuticals, Inc. Intranasal administration of esketamine
TW202135787A (en) 2019-12-12 2021-10-01 比利時商健生藥品公司 Esketamine formulations and methods for preparation and storage
WO2021137148A1 (en) 2019-12-30 2021-07-08 Clexio Biosciences Ltd. Dosage regime with esketamine for treating neuropsychiatric or neurological conditions
US20230063459A1 (en) 2019-12-30 2023-03-02 Clexio Biosciences Ltd. Dosage regime with esketamine for treating major depressive disorder
AU2021364293A1 (en) * 2020-10-22 2023-06-08 Tonix Pharmaceuticals Holding Corp. Randomization honoring methods to assess the significance of interventions on outcomes in disorders
WO2024201274A1 (en) * 2023-03-24 2024-10-03 Janssen Pharmaceutica Nv Esketamine for use in the treatment of depression

Family Cites Families (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10025A (en) 1853-09-20 Improvement in turbines
CH535201A (en) 1969-12-19 1973-03-31 Bristol Myers Co Process for the resolution of racemic 2- (o-chlorophenyl) -2-methylaminocyclohexanone into the optically active isomers
JPS632932A (en) 1986-06-23 1988-01-07 Teijin Ltd Powdery composition for nasal administration
US5002935A (en) 1987-12-30 1991-03-26 University Of Florida Improvements in redox systems for brain-targeted drug delivery
US4994467A (en) 1989-05-31 1991-02-19 Zimmerman Andrew W Treating autism and other developmental disorders in children with NMDA receptor antagonists
DE4312016A1 (en) 1993-04-13 1994-10-20 Goedecke Ag Stable ketamine solutions
US5543434A (en) 1994-02-25 1996-08-06 Weg; Stuart L. Nasal administration of ketamine to manage pain
ES2205018T3 (en) 1995-02-24 2004-05-01 Stuart Weg KETAMINE ADMINISTRATION FOR DETOXIFICATION.
JPH11511466A (en) 1995-08-30 1999-10-05 スチュアート エル ウェグ Administration of ketamine to manage pain and reduce drug dependence
FR2739294B1 (en) 1995-09-29 1998-01-16 Lhd Lab Hygiene Dietetique NASAL SAFETY TIP
DE19619665C2 (en) 1996-05-15 2001-03-08 Goedecke Ag Racemate separation of ketamine
DE19723133A1 (en) 1997-06-03 1998-12-10 Caideil M P Teoranta Tourmakea Discharge device for media
FR2764807B1 (en) 1997-06-18 1999-08-20 Valois Sa NASAL DISPENSING DEVICE FOR A FLUID OR POWDERY PRODUCT
EP1113785B1 (en) 1998-07-24 2005-04-13 Seo Hong Yoo Clear aqueous solutions of bile acids
US6599883B1 (en) 1998-10-30 2003-07-29 Nastech Pharmaceutical Company, Inc. Nasal delivery of xylitol
US6176242B1 (en) 1999-04-30 2001-01-23 Medtronic Inc Method of treating manic depression by brain infusion
US6017961A (en) 1999-07-08 2000-01-25 Flores; John Anthony Ketamine and n-butyl-p-aminobezoate in PLO
EP1103256A1 (en) 1999-11-26 2001-05-30 Claudius Dr. med. Böck Use of ketamine for the treatment of neuroendocrine immune dysfunction und algogenic psychosyndrome
AU2001291159A1 (en) 2000-09-20 2002-04-02 Shahinian Jr., Lee Self-preserved nasal, inhalable, and topical ophthalmic preparations and medications
US6881731B1 (en) 2000-10-23 2005-04-19 Shanbrom Technologies, Llc Enhancers for microbiological disinfection
MXPA05000294A (en) 2002-07-30 2005-08-19 Peter Migaly Combination therapy for depression, prevention of suicide, and varous medical and psychiatric conditions.
US7273889B2 (en) 2002-09-25 2007-09-25 Innovative Drug Delivery Systems, Inc. NMDA receptor antagonist formulation with reduced neurotoxicity
DE60327883D1 (en) 2002-11-18 2009-07-16 Yaupon Therapeutics Inc ANALGETIC USE OF (S) -NORKETAMINE
US7687080B2 (en) 2002-11-25 2010-03-30 Taraxos Inc. Treatment of neuropathy
US20040214215A1 (en) 2003-03-07 2004-10-28 Yu Ruey J. Bioavailability and improved delivery of alkaline pharmaceutical drugs
US8082173B2 (en) 2003-05-22 2011-12-20 Cecil Kost Drug sample fulfillment architecture
US20040265364A1 (en) 2003-06-25 2004-12-30 Binnur Ozturk Neuropathy cream
US20050095277A1 (en) 2003-06-25 2005-05-05 Binnur Ozturk Neuropathy cream
US20060223788A1 (en) 2005-03-29 2006-10-05 Cathcart Clifton H Analgesic composition for topical use
US7896850B2 (en) 2005-06-01 2011-03-01 Telefonaktiebolaget L M Ericsson (Publ) Device for delivering medicament
US20060276550A1 (en) 2005-06-03 2006-12-07 Dileep Bhagwat Topical compositions of ketamine and butamben and methods of their use
US8785500B2 (en) 2006-03-22 2014-07-22 Icahn School Of Medicine At Mount Sinai Intranasal administration of ketamine to treat depression
WO2007123945A2 (en) 2006-04-21 2007-11-01 Aradigm Corporation Mechanical single dose intrapulmonary drug delivery devices
AU2007253684A1 (en) 2006-05-22 2007-11-29 Vanda Pharmaceuticals, Inc. Treatment for depressive disorders
DE102007009888A1 (en) 2007-02-28 2008-09-04 Hermann, Holger Lars, Dr. Use of S-(+)-ketamine for treating depression, which is therapy-refractive depression, preferably depressive episode, relapsing disorder and bipolar affective disorder
US7745665B2 (en) 2007-06-04 2010-06-29 Auspex Pharmaceuticals, Inc. Substituted phenethylamines
US8710070B2 (en) 2008-03-27 2014-04-29 University Of Kentucky Research Foundation Opioid-ketamine and norketamine codrug combinations for pain management
US20110038807A1 (en) 2009-08-14 2011-02-17 Demitri Papolos Compositions and methods for treating bipolar disorder
US20120225949A1 (en) 2009-08-14 2012-09-06 Demitri Papalos Compositions and methods for treating bipolar disorder
KR101831616B1 (en) 2010-06-15 2018-04-04 그뤼넨탈 게엠베하 Pharmaceutical combination for the treatment of pain
US9073819B2 (en) 2011-06-30 2015-07-07 University Of South Florida Compositions, methods of use, and methods of treatment
EP3904332A1 (en) 2011-10-14 2021-11-03 The United States of America, as represented by The Secretary, Department of Health and Human Services The use of (2r, 6r)-hydroxynorketamine, (s)-dehydronorketamine and other stereoisomeric dehydro and hydroxylated metabolites of (r,s)- ketamine in the treatment of depression and neuropathic pain
IN2014DN04226A (en) 2011-11-14 2015-05-22 Gen Hospital Corp
US20130209585A1 (en) 2012-02-13 2013-08-15 Stanley Kim Topical NMDA Antagonist Formulations for the Treatment of Peripheral Neuropathy
WO2013138322A1 (en) * 2012-03-12 2013-09-19 Janssen Pharmaceutica Nv Esketamine for the treatment of treatment-refractory or treatment-resistant depression
AU2016203771A1 (en) 2012-03-13 2016-06-23 Janssen Pharmaceutica Nv Esketamine for the treatment of treatment-refractory or treatment-resistant depression
JP2015512418A (en) 2012-03-30 2015-04-27 ザ ジェネラル ホスピタル コーポレイション Compositions containing scopolamine and ketamine in the treatment of depression
US20140079740A1 (en) 2012-08-02 2014-03-20 ClinPharm Support GmbH Oral transmucosal adminstration forms of s-ketamine
WO2014031975A1 (en) 2012-08-23 2014-02-27 Weg Stuart L Anxiolytic composition, formulation and method of use
FR2994844B1 (en) 2012-08-31 2015-01-02 Assist Publ Hopitaux De Paris GELIFYING FORMULATION BASED ON KETAMINE
NZ619257A (en) 2012-10-08 2015-07-31 Auckland Uniservices Ltd Ketamine derivatives
ES2484068B1 (en) 2013-02-08 2015-04-16 Ana MÍNGUEZ MARTÍ A pharmaceutical composition containing ketamine and amitriptyline
KR102424765B1 (en) 2013-04-12 2022-07-22 이칸 스쿨 오브 메디슨 엣 마운트 시나이 Method for treating post-traumatic stress disorder
JP2016531913A (en) 2013-08-26 2016-10-13 アモーサ セラピューティックス， インコーポレイテッドＡｍｏｒｓａ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． Oral administration of a neurosuppressive ketamine monolayer
RS62516B1 (en) 2013-09-13 2021-11-30 Univ Chiba Nat Univ Corp Application of r-ketamine and salt thereof as pharmaceuticals
CN103705909A (en) 2013-12-16 2014-04-09 陈镜伊 Drug for painless induced abortion
WO2015101693A1 (en) 2013-12-31 2015-07-09 Servicio Andaluz De Salud Combined preparations and compositions for the treatment of oropharyngeal pain
CA2936809A1 (en) 2014-01-14 2015-07-23 Children's Hospital Medical Center Compositions comprising ketamine for treating an autism spectrum disorder
ES2935800T3 (en) 2014-04-17 2023-03-10 Ketabon Gmbh Ketamine Oral Dosage Form
US20170071242A1 (en) 2014-05-04 2017-03-16 Interquim Sa Flavored food and beverage products
FR3023188B1 (en) 2014-07-04 2016-08-19 Aptar France Sas DEVICE FOR DISPENSING FLUID PRODUCT.
US10098854B2 (en) 2014-08-13 2018-10-16 Janssen Pharmaceutica Nv Method for the treatment of depression
CN107208133A (en) * 2014-09-15 2017-09-26 詹森药业有限公司 Val66Met (SNPrs6265) Serotype-dependent dosage regimens and method for treating depression
US20180015054A1 (en) 2014-12-31 2018-01-18 Icahn School Of Medicine At Mount Sinai Method of Maintaining the Anti-Depressant Effect of Ketamine With Lithium
CN104798728A (en) 2015-05-08 2015-07-29 南京中医药大学 Creation method and applications of postpartum depression animal models
US20160332962A1 (en) 2015-05-13 2016-11-17 Janssen Pharmaceutica Nv (s)-csa salt of s-ketamine, (r)-csa salt of s-ketamine and processes for the preparation of s-ketamine
US20160338977A1 (en) 2015-05-20 2016-11-24 Janssen Pharmaceutica Nv Methods and kits for treating depression
JP6845162B2 (en) 2015-06-27 2021-03-17 シェノックス・ファーマシューティカルズ・エルエルシー Ketamine transdermal delivery system
US20180296478A1 (en) 2016-02-12 2018-10-18 Synergistic Therapeutics, Llc Sublingual antidepressant and antianxiety tablet
US20180042936A1 (en) 2016-03-18 2018-02-15 Genomind, Inc. Maintenance therapy using tianeptine
SG11202005896WA (en) 2017-12-22 2020-07-29 Janssen Pharmaceuticals Inc Esketamine for the treatment of depression

Also Published As

Publication number Publication date
TW201940162A (en) 2019-10-16
WO2019126108A1 (en) 2019-06-27
JOP20200156A1 (en) 2022-10-30
EP3501542A1 (en) 2019-06-26
BR112020012473A2 (en) 2020-11-24
MX2023012450A (en) 2023-10-31
PH12020500555A1 (en) 2021-05-17
JP2021506924A (en) 2021-02-22
TWI843711B (en) 2024-06-01
CN117531017A (en) 2024-02-09
CN112423789A (en) 2021-02-26
RU2020123893A3 (en) 2022-04-29
US20240000728A1 (en) 2024-01-04
KR20200113197A (en) 2020-10-06
CA3086478A1 (en) 2019-06-27
US11707440B2 (en) 2023-07-25
JP2024001204A (en) 2024-01-09
RU2020123893A (en) 2022-01-24
MA47719A (en) 2020-01-15
IL275482A (en) 2020-08-31
AU2018282466A1 (en) 2019-07-11
US20210386688A1 (en) 2021-12-16
KR20240011237A (en) 2024-01-25
MX2020006650A (en) 2020-11-06
TW202415363A (en) 2024-04-16

Similar Documents

Publication Publication Date Title
IL275482A (en) Esketamine for the treatment of depression
IL279627A (en) Method for the treatment of depression
IL269371A (en) Treatment methods
GB201707153D0 (en) Therapy
GB201608885D0 (en) Treatment
HK1258276A1 (en) Compounds and combinations for the treatment of hiv
IL283948A (en) Methods for the treatment of depression
GB201813876D0 (en) Treatment
GB201719646D0 (en) Therapy
GB201708663D0 (en) Therapy
GB201813986D0 (en) Coffins
HK1257272A1 (en) Means for the treatment of hiv
IL286000A (en) Esketamine for the treatment of depression
HK1247558A1 (en) Cenicriviroc for the treatment of fibrosis
GB201800546D0 (en) Treatment
PL3484475T3 (en) 1-methylnicotinamide for the treatment of cardiovascular disease
PL3448340T3 (en) Application aid for the treatment of wounds
EP3145525A4 (en) Use of microperoxidases for the treatment of carboxyhemoglobinemia
IL272658A (en) Surface treatment
ZA201906319B (en) Methods of treating depression
GB201718985D0 (en) Treatment
ZA201805215B (en) Preparation for nasal-nasopharyngeal treatment
GB201713650D0 (en) Treatment
GB201814905D0 (en) Treatment
GB201706955D0 (en) Treatment