NZ619257A - Ketamine derivatives - Google Patents
Ketamine derivativesInfo
- Publication number
- NZ619257A NZ619257A NZ619257A NZ61925712A NZ619257A NZ 619257 A NZ619257 A NZ 619257A NZ 619257 A NZ619257 A NZ 619257A NZ 61925712 A NZ61925712 A NZ 61925712A NZ 619257 A NZ619257 A NZ 619257A
- Authority
- NZ
- New Zealand
- Prior art keywords
- oxocyclohexyl
- chlorophenyl
- amino
- compounds
- butanoate
- Prior art date
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
This disclosure relates to a family of compounds of formula (I). These are ketamine derivatives wherein Y1, Y2, X1 and X2 are as defined in the specification. The disclosure also related to pharmaceutical compositions comprising these compounds and methods of providing provide pain relief or analgesia and inducing and maintaining general anesthesia or sedation using these compounds. Examples of the compounds include: 3-((1-(2-chlorophenyl)-2-oxocyclohexyl)amino)propyl acetate, n-propyl 3-((1-(2-chlorophenyl)-2-oxocyclohexyl)amino)propanoate, ethyl4-((1-(2-chlorophenyl)-2-oxocyclohexyl)amino)butanoate, isopropyl 5-((1-(2-chlorophenyl)-2-oxocyclohexyl)amino)pentanoate and ethyl 4-((1-(2-chlorophenyl)-2-oxocyclohexyl)(methyl)amino)butanoate.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NZ619257A NZ619257A (en) | 2012-10-08 | 2012-10-08 | Ketamine derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NZ619257A NZ619257A (en) | 2012-10-08 | 2012-10-08 | Ketamine derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
NZ619257A true NZ619257A (en) | 2015-07-31 |
Family
ID=53773589
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NZ619257A NZ619257A (en) | 2012-10-08 | 2012-10-08 | Ketamine derivatives |
Country Status (1)
Country | Link |
---|---|
NZ (1) | NZ619257A (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10869844B2 (en) | 2014-09-15 | 2020-12-22 | Janssen Pharmaceutica Nv | Methods for the treatment of depression |
US11446260B2 (en) | 2013-03-15 | 2022-09-20 | Janssen Pharmaceutica Nv | Pharmaceutical composition of S-ketamine hydrochloride |
US11707440B2 (en) | 2017-12-22 | 2023-07-25 | Janssen Pharmaceuticals, Inc. | Esketamine for the treatment of depression |
US11883526B2 (en) | 2019-03-05 | 2024-01-30 | Janssen Pharmaceutica Nv | Esketamine for the treatment of depression |
US11980596B2 (en) | 2017-09-13 | 2024-05-14 | Janssen Pharmaceutica Nv | Delivery of esketamine for the treatment of depression |
-
2012
- 2012-10-08 NZ NZ619257A patent/NZ619257A/en not_active IP Right Cessation
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11446260B2 (en) | 2013-03-15 | 2022-09-20 | Janssen Pharmaceutica Nv | Pharmaceutical composition of S-ketamine hydrochloride |
US10869844B2 (en) | 2014-09-15 | 2020-12-22 | Janssen Pharmaceutica Nv | Methods for the treatment of depression |
US11173134B2 (en) | 2014-09-15 | 2021-11-16 | Janssen Pharmaceutica Nv | Methods for the treatment of depression |
US11311500B2 (en) | 2014-09-15 | 2022-04-26 | Janssen Pharmaceutica Nv | Methods for the treatment of depression |
US11980596B2 (en) | 2017-09-13 | 2024-05-14 | Janssen Pharmaceutica Nv | Delivery of esketamine for the treatment of depression |
US11707440B2 (en) | 2017-12-22 | 2023-07-25 | Janssen Pharmaceuticals, Inc. | Esketamine for the treatment of depression |
US11883526B2 (en) | 2019-03-05 | 2024-01-30 | Janssen Pharmaceutica Nv | Esketamine for the treatment of depression |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PSEA | Patent sealed | ||
RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 19 DEC 2018 BY PATRIX IP SERVICES Effective date: 20171025 |
|
RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 19 DEC 2019 BY AJ PARK Effective date: 20181112 |
|
RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 19 DEC 2020 BY AJ PARK Effective date: 20191112 |
|
LAPS | Patent lapsed |