MX2020013927A - Derivados de benzodiazepina, composiciones y metodos para tratar el deterioro cognitivo. - Google Patents
Derivados de benzodiazepina, composiciones y metodos para tratar el deterioro cognitivo.Info
- Publication number
- MX2020013927A MX2020013927A MX2020013927A MX2020013927A MX2020013927A MX 2020013927 A MX2020013927 A MX 2020013927A MX 2020013927 A MX2020013927 A MX 2020013927A MX 2020013927 A MX2020013927 A MX 2020013927A MX 2020013927 A MX2020013927 A MX 2020013927A
- Authority
- MX
- Mexico
- Prior art keywords
- sub
- cognitive impairment
- compositions
- containing gaba
- treating
- Prior art date
Links
- 208000010877 cognitive disease Diseases 0.000 title abstract 9
- 208000028698 Cognitive impairment Diseases 0.000 title abstract 6
- 239000000203 mixture Substances 0.000 title abstract 3
- 229940053197 benzodiazepine derivative antiepileptics Drugs 0.000 title abstract 2
- 125000003310 benzodiazepinyl group Chemical class N1N=C(C=CC2=C1C=CC=C2)* 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 229960003692 gamma aminobutyric acid Drugs 0.000 abstract 4
- BTCSSZJGUNDROE-UHFFFAOYSA-N gamma-aminobutyric acid Chemical compound NCCCC(O)=O BTCSSZJGUNDROE-UHFFFAOYSA-N 0.000 abstract 4
- 208000027061 mild cognitive impairment Diseases 0.000 abstract 3
- 208000003174 Brain Neoplasms Diseases 0.000 abstract 2
- 208000015114 central nervous system disease Diseases 0.000 abstract 2
- 229940126027 positive allosteric modulator Drugs 0.000 abstract 2
- 239000000018 receptor agonist Substances 0.000 abstract 2
- 229940044601 receptor agonist Drugs 0.000 abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 208000020925 Bipolar disease Diseases 0.000 abstract 1
- 206010012289 Dementia Diseases 0.000 abstract 1
- 208000000172 Medulloblastoma Diseases 0.000 abstract 1
- 208000036626 Mental retardation Diseases 0.000 abstract 1
- 208000018737 Parkinson disease Diseases 0.000 abstract 1
- 208000006289 Rett Syndrome Diseases 0.000 abstract 1
- 230000007000 age related cognitive decline Effects 0.000 abstract 1
- 206010002026 amyotrophic lateral sclerosis Diseases 0.000 abstract 1
- 208000029560 autism spectrum disease Diseases 0.000 abstract 1
- 231100000867 compulsive behavior Toxicity 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 206010027175 memory impairment Diseases 0.000 abstract 1
- 238000011275 oncology therapy Methods 0.000 abstract 1
- 208000028173 post-traumatic stress disease Diseases 0.000 abstract 1
- 201000000980 schizophrenia Diseases 0.000 abstract 1
- 208000011117 substance-related disease Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862687195P | 2018-06-19 | 2018-06-19 | |
| PCT/US2019/038038 WO2019246300A1 (en) | 2018-06-19 | 2019-06-19 | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2020013927A true MX2020013927A (es) | 2021-03-02 |
Family
ID=68984202
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2020013927A MX2020013927A (es) | 2018-06-19 | 2019-06-19 | Derivados de benzodiazepina, composiciones y metodos para tratar el deterioro cognitivo. |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US11414425B2 (https=) |
| EP (1) | EP3810611A4 (https=) |
| JP (1) | JP7514534B2 (https=) |
| CN (1) | CN112601749B (https=) |
| AU (1) | AU2019288382B2 (https=) |
| BR (1) | BR112020026062B1 (https=) |
| CA (1) | CA3104478A1 (https=) |
| EA (1) | EA202190076A1 (https=) |
| IL (1) | IL279530B2 (https=) |
| MX (1) | MX2020013927A (https=) |
| WO (1) | WO2019246300A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3083569B1 (en) | 2013-12-20 | 2022-01-26 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| JP6987384B2 (ja) | 2015-06-19 | 2021-12-22 | エージンバイオ， インコーポレイテッド | ベンゾジアゼピン誘導体、組成物、および認知障害を処置するための方法 |
| US20180170941A1 (en) | 2016-12-19 | 2018-06-21 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| US11505555B2 (en) * | 2016-12-19 | 2022-11-22 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| US11414425B2 (en) | 2018-06-19 | 2022-08-16 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| IL294031A (en) * | 2019-12-19 | 2022-08-01 | Agenebio Inc | History of benzodiazepines, preparations and methods for the treatment of cognitive impairment |
| CA3189302A1 (en) * | 2020-07-10 | 2022-01-13 | Agenebio, Inc. | Combinations of gabaa alpha 5 agonists and sv2a inhibitors and methods of using in the treatment of cognitive impairment |
| JP2023534190A (ja) * | 2020-07-10 | 2023-08-08 | エージンバイオ， インコーポレイテッド | ＧＡＢＡＡα５アゴニストの多形および認知障害の処置において使用する方法 |
| US20260033761A1 (en) | 2022-07-29 | 2026-02-05 | Hoffmann-La Roche Inc. | Characterisation of neurological dysfunction |
| WO2024039886A1 (en) | 2022-08-19 | 2024-02-22 | Agenebio, Inc. | Benzazepine derivatives, compositions, and methods for treating cognitive impairment |
| CN117756848A (zh) * | 2023-11-30 | 2024-03-26 | 常州大学 | 一种th-302衍生物及其制备方法 |
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| JP6987384B2 (ja) | 2015-06-19 | 2021-12-22 | エージンバイオ， インコーポレイテッド | ベンゾジアゼピン誘導体、組成物、および認知障害を処置するための方法 |
| US11505555B2 (en) | 2016-12-19 | 2022-11-22 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| US20180170941A1 (en) | 2016-12-19 | 2018-06-21 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| CN108567786A (zh) * | 2017-03-10 | 2018-09-25 | 陈洪国 | 一种治疗溃疡性结肠炎的药物组合物 |
| CN108567787A (zh) * | 2017-03-10 | 2018-09-25 | 辛衍雪 | 一种治疗慢性阻塞性肺病的药物组合物 |
| US11414425B2 (en) | 2018-06-19 | 2022-08-16 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
-
2019
- 2019-06-19 US US16/445,854 patent/US11414425B2/en active Active
- 2019-06-19 MX MX2020013927A patent/MX2020013927A/es unknown
- 2019-06-19 CN CN201980053122.8A patent/CN112601749B/zh active Active
- 2019-06-19 CA CA3104478A patent/CA3104478A1/en active Pending
- 2019-06-19 AU AU2019288382A patent/AU2019288382B2/en active Active
- 2019-06-19 EA EA202190076A patent/EA202190076A1/ru unknown
- 2019-06-19 IL IL279530A patent/IL279530B2/en unknown
- 2019-06-19 JP JP2020571354A patent/JP7514534B2/ja active Active
- 2019-06-19 BR BR112020026062-2A patent/BR112020026062B1/pt not_active IP Right Cessation
- 2019-06-19 EP EP19822528.6A patent/EP3810611A4/en active Pending
- 2019-06-19 WO PCT/US2019/038038 patent/WO2019246300A1/en not_active Ceased
-
2022
- 2022-06-27 US US17/850,144 patent/US12291535B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| NZ772066A (en) | 2025-05-30 |
| EP3810611A1 (en) | 2021-04-28 |
| US12291535B2 (en) | 2025-05-06 |
| US20200048268A1 (en) | 2020-02-13 |
| CA3104478A1 (en) | 2019-12-26 |
| WO2019246300A1 (en) | 2019-12-26 |
| EA202190076A1 (ru) | 2021-09-22 |
| CN112601749A (zh) | 2021-04-02 |
| CN112601749B (zh) | 2024-03-26 |
| EP3810611A4 (en) | 2022-03-30 |
| US11414425B2 (en) | 2022-08-16 |
| AU2019288382A1 (en) | 2021-02-11 |
| JP7514534B2 (ja) | 2024-07-11 |
| JP2021528427A (ja) | 2021-10-21 |
| IL279530B2 (en) | 2026-01-01 |
| IL279530A (en) | 2021-01-31 |
| IL279530B1 (en) | 2025-09-01 |
| US20230107032A1 (en) | 2023-04-06 |
| BR112020026062A2 (pt) | 2021-03-23 |
| BR112020026062B1 (pt) | 2023-04-04 |
| AU2019288382B2 (en) | 2024-07-25 |
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