MX2019012295A - Polinucleotidos inmunomoduladores, conjugados de anticuerpos de los mismos y metodos para su uso. - Google Patents

Polinucleotidos inmunomoduladores, conjugados de anticuerpos de los mismos y metodos para su uso.

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Publication number
MX2019012295A
MX2019012295A MX2019012295A MX2019012295A MX2019012295A MX 2019012295 A MX2019012295 A MX 2019012295A MX 2019012295 A MX2019012295 A MX 2019012295A MX 2019012295 A MX2019012295 A MX 2019012295A MX 2019012295 A MX2019012295 A MX 2019012295A
Authority
MX
Mexico
Prior art keywords
polynucleotides
immunomodulatory
methods
conjugates
antibody conjugates
Prior art date
Application number
MX2019012295A
Other languages
English (en)
Spanish (es)
Inventor
Sakamuri Sukumar
W Bradshaw Curt
Lam Son
Stock Joseph
Hyungsuk Ha Edward
Eltepu Laxman
Liu Dingguo
Liu Bin
Dello Iacono Giuseppe
Kabakibi Ayman
R Meade Bryan
Original Assignee
Tollnine Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tollnine Inc filed Critical Tollnine Inc
Publication of MX2019012295A publication Critical patent/MX2019012295A/es

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    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
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    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/7125—Nucleic acids or oligonucleotides having modified internucleoside linkage, i.e. other than 3'-5' phosphodiesters
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