MX2019008064A - Estrategia optimizada para modificaciones de omisión de exones mediante el uso de crispr / cas9 con secuencias guía triples. - Google Patents

Estrategia optimizada para modificaciones de omisión de exones mediante el uso de crispr / cas9 con secuencias guía triples.

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Publication number
MX2019008064A
MX2019008064A MX2019008064A MX2019008064A MX2019008064A MX 2019008064 A MX2019008064 A MX 2019008064A MX 2019008064 A MX2019008064 A MX 2019008064A MX 2019008064 A MX2019008064 A MX 2019008064A MX 2019008064 A MX2019008064 A MX 2019008064A
Authority
MX
Mexico
Prior art keywords
cas9
crispr
modifications
exon skipping
guide sequences
Prior art date
Application number
MX2019008064A
Other languages
English (en)
Spanish (es)
Inventor
Eric Olson
Leonela Amoasii
Original Assignee
Univ Texas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Texas filed Critical Univ Texas
Publication of MX2019008064A publication Critical patent/MX2019008064A/es

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    • C12N9/14—Hydrolases (3)
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    • C12N2310/00—Structure or type of the nucleic acid
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MX2019008064A 2017-01-05 2018-01-05 Estrategia optimizada para modificaciones de omisión de exones mediante el uso de crispr / cas9 con secuencias guía triples. MX2019008064A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201762442606P 2017-01-05 2017-01-05
US201762544449P 2017-08-11 2017-08-11
US201762596298P 2017-12-08 2017-12-08
PCT/US2018/012558 WO2018129296A1 (en) 2017-01-05 2018-01-05 Optimized strategy for exon skipping modifications using crispr/cas9 with triple guide sequences

Publications (1)

Publication Number Publication Date
MX2019008064A true MX2019008064A (es) 2020-07-20

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MX2019008064A MX2019008064A (es) 2017-01-05 2018-01-05 Estrategia optimizada para modificaciones de omisión de exones mediante el uso de crispr / cas9 con secuencias guía triples.

Country Status (22)

Country Link
US (1) US20190338311A1 (OSRAM)
EP (1) EP3565897B1 (OSRAM)
JP (1) JP2020503869A (OSRAM)
KR (1) KR102606174B1 (OSRAM)
CN (1) CN110506115A (OSRAM)
AU (1) AU2018205521A1 (OSRAM)
BR (1) BR112019013962A2 (OSRAM)
CA (1) CA3048635A1 (OSRAM)
CL (1) CL2019001882A1 (OSRAM)
CO (1) CO2019008181A2 (OSRAM)
CR (1) CR20190326A (OSRAM)
DK (1) DK3565897T3 (OSRAM)
DO (1) DOP2019000179A (OSRAM)
EC (1) ECSP19056408A (OSRAM)
IL (1) IL267786A (OSRAM)
JO (1) JOP20190166A1 (OSRAM)
MA (1) MA47239A (OSRAM)
MX (1) MX2019008064A (OSRAM)
PE (1) PE20191357A1 (OSRAM)
PH (1) PH12019501561A1 (OSRAM)
SG (1) SG11201906147VA (OSRAM)
WO (1) WO2018129296A1 (OSRAM)

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CN115011598A (zh) * 2020-09-02 2022-09-06 西湖大学 杜氏肌营养不良症相关的外显子剪接增强子、sgRNA、基因编辑工具及应用
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