MX2019007719A - Anticuerpo anti-receptor de transferrina humana novedoso capaz de penetrar la barrera hematoencefalica. - Google Patents

Anticuerpo anti-receptor de transferrina humana novedoso capaz de penetrar la barrera hematoencefalica.

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Publication number
MX2019007719A
MX2019007719A MX2019007719A MX2019007719A MX2019007719A MX 2019007719 A MX2019007719 A MX 2019007719A MX 2019007719 A MX2019007719 A MX 2019007719A MX 2019007719 A MX2019007719 A MX 2019007719A MX 2019007719 A MX2019007719 A MX 2019007719A
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MX
Mexico
Prior art keywords
seq
transferrin receptor
receptor antibody
human transferrin
brain barrier
Prior art date
Application number
MX2019007719A
Other languages
English (en)
Inventor
Sonoda Hiroyuki
Takahashi Kenichi
Original Assignee
Japan Chem Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japan Chem Res filed Critical Japan Chem Res
Publication of MX2019007719A publication Critical patent/MX2019007719A/es

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Abstract

Se proporciona un anticuerpo anti-receptor de transferrina humana o un análogo del mismo, en donde, en la región variable de cadena pesada del anticuerpo, (a) CDR1 comprende la secuencia de aminoácidos definida como SEQ ID NO: 62 o SEQ ID NO: 63, (b) CDR2 comprende la secuencia de aminoácidos definida como SEQ ID NO: 13 o SEQ ID NO: 14, y (c) CDR3 comprende la secuencia de aminoácidos definida como SEQ ID NO: 15 o SEQ ID NO: 16, y un análogo de las mismas.
MX2019007719A 2016-12-26 2017-12-26 Anticuerpo anti-receptor de transferrina humana novedoso capaz de penetrar la barrera hematoencefalica. MX2019007719A (es)

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